DK0722457T3 - Forbindelser, der modificerer den serotoninerge transmission, og diagnostisk og terapeutisk anvendelse af sådanne forbindelser - Google Patents

Forbindelser, der modificerer den serotoninerge transmission, og diagnostisk og terapeutisk anvendelse af sådanne forbindelser

Info

Publication number: DK0722457T3
Authority: DK; Denmark
Prior art keywords: compounds; peptide; leu; diagnostic; modify
Prior art date: 1993-10-04

Application number

DK94929577T

Other languages

Danish (da)

English (en)

Inventor

Gilles Fillion

Jean-Claude Rousselle

Olivier Massot

Original Assignee

Pasteur Institut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-04

Filing date

1994-10-04

Publication date

2002-04-22

1993-10-04 Priority claimed from FR9311804A external-priority patent/FR2710916B1/fr

1994-06-09 Priority claimed from FR9407079A external-priority patent/FR2721030B1/fr

1994-06-09 Priority claimed from FR9407078A external-priority patent/FR2721029B1/fr

1994-10-04 Application filed by Pasteur Institut filed Critical Pasteur Institut

2002-04-22 Application granted granted Critical

2002-04-22 Publication of DK0722457T3 publication Critical patent/DK0722457T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 5
230000005540 biological transmission Effects 0.000 title 1
230000002295 serotoninergic effect Effects 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 6
230000007515 enzymatic degradation Effects 0.000 abstract 2
DCVYRWFAMZFSDA-ZLUOBGJFSA-N Ala-Ser-Ala Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O DCVYRWFAMZFSDA-ZLUOBGJFSA-N 0.000 abstract 1
IRMLZWSRWSGTOP-CIUDSAMLSA-N Leu-Ser-Ala Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O IRMLZWSRWSGTOP-CIUDSAMLSA-N 0.000 abstract 1
108091005804 Peptidases Proteins 0.000 abstract 1
239000004365 Protease Substances 0.000 abstract 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Motor Or Generator Cooling System (AREA)

DK94929577T 1993-10-04 1994-10-04 Forbindelser, der modificerer den serotoninerge transmission, og diagnostisk og terapeutisk anvendelse af sådanne forbindelser DK0722457T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR9311804A FR2710916B1 (fr)	1993-10-04	1993-10-04	Composés de nature peptidique ayant une activité modulatrice de la réponse sérotoninergique; applications diagnostiques et thérapeutiques.
FR9407079A FR2721030B1 (fr)	1994-06-09	1994-06-09	Composés modifiant la transmission sérotoninergique; applications diagnostiques et thérapeutiques.
FR9407078A FR2721029B1 (fr)	1994-06-09	1994-06-09	Composés modifiant la transmission sérotoninergique; applications diagnostiques et thérapeutiques.
PCT/FR1994/001158 WO1995009868A1 (fr)	1993-10-04	1994-10-04	Composes modifiant la transmission serotoninergique; applications diagnostiques et therapeutiques

Publications (1)

Publication Number	Publication Date
DK0722457T3 true DK0722457T3 (da)	2002-04-22

Family

ID=27252801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94929577T DK0722457T3 (da)	1993-10-04	1994-10-04	Forbindelser, der modificerer den serotoninerge transmission, og diagnostisk og terapeutisk anvendelse af sådanne forbindelser

Country Status (12)

Country	Link
US (1)	US6713443B1 (de)
EP (1)	EP0722457B1 (de)
JP (1)	JPH09503220A (de)
KR (1)	KR960704921A (de)
AT (1)	ATE211483T1 (de)
AU (1)	AU678298B2 (de)
CA (1)	CA2173460A1 (de)
DE (1)	DE69429582T2 (de)
DK (1)	DK0722457T3 (de)
ES (1)	ES2170105T3 (de)
PT (1)	PT722457E (de)
WO (1)	WO1995009868A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6759510B1 (en)	2000-06-30	2004-07-06	Becton, Dickinson And Company	Peptides for use in culture media
TWI328457B (en) *	2003-03-18	2010-08-11	Suntory Holdings Ltd	Angiotensin-converting enzyme inhibitory peptides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5647895B2 (de) *	1973-06-08	1981-11-12
RO80806A (ro)	1979-04-06	1983-02-01	De Forenede Bryggerier As,Dk	Procedeu pentru obtinerea enzimatica a peptidelor
US4793986A (en) *	1987-02-25	1988-12-27	Johnson Matthey, Inc.	Macromolecular platinum antitumor compounds
SE8803847A0 (sv)	1988-10-27	1990-04-28	Kabigen Ab	Neuromodulerande peptid
US5104854A (en) *	1989-02-01	1992-04-14	Washington University	Antiviral peptides
FR2657784A1 (fr)	1990-02-05	1991-08-09	Pasteur Institut	Facteur endogene cerebral, procede d'obtention et applications therapeutiques et diagnostiques.
JPH0421635A (ja) *	1990-05-16	1992-01-24	Suntory Ltd	アセトアルデヒドの毒性抑制剤およびアセトアルデヒドの毒性抑制に有効な飲食物

1994
- 1994-10-04 US US08/624,618 patent/US6713443B1/en not_active Expired - Fee Related
- 1994-10-04 AT AT94929577T patent/ATE211483T1/de not_active IP Right Cessation
- 1994-10-04 JP JP7510646A patent/JPH09503220A/ja active Pending
- 1994-10-04 DE DE69429582T patent/DE69429582T2/de not_active Expired - Fee Related
- 1994-10-04 CA CA002173460A patent/CA2173460A1/fr not_active Abandoned
- 1994-10-04 KR KR1019960701742A patent/KR960704921A/ko not_active Withdrawn
- 1994-10-04 WO PCT/FR1994/001158 patent/WO1995009868A1/fr not_active Ceased
- 1994-10-04 DK DK94929577T patent/DK0722457T3/da active
- 1994-10-04 ES ES94929577T patent/ES2170105T3/es not_active Expired - Lifetime
- 1994-10-04 AU AU78579/94A patent/AU678298B2/en not_active Ceased
- 1994-10-04 EP EP94929577A patent/EP0722457B1/de not_active Expired - Lifetime
- 1994-10-04 PT PT94929577T patent/PT722457E/pt unknown

Also Published As

Publication number	Publication date
PT722457E (pt)	2002-06-28
CA2173460A1 (fr)	1995-04-13
EP0722457A1 (de)	1996-07-24
US6713443B1 (en)	2004-03-30
DE69429582D1 (de)	2002-02-07
AU7857994A (en)	1995-05-01
KR960704921A (ko)	1996-10-09
DE69429582T2 (de)	2002-08-22
ES2170105T3 (es)	2002-08-01
WO1995009868A1 (fr)	1995-04-13
AU678298B2 (en)	1997-05-22
ATE211483T1 (de)	2002-01-15
JPH09503220A (ja)	1997-03-31
EP0722457B1 (de)	2002-01-02

Publication	Publication Date	Title
ES8802129A1 (es)	1988-04-01	Procedimiento para preparar un analogo polipeptido inhibidorde resina
EP1502949A4 (de)	2006-03-15	Antimikrobielles polypeptid und nutzung davon
DK0728148T3 (da)	1999-09-27	Forbedrede immunogene sammensætninger mod humant gastrin 17
ATE284962T1 (de)	2005-01-15	Subtilisin varianten
MX9605357A (es)	1997-12-31	Variantes de subtilisina bpn' que tiene absorcion reducida e hidrolisis incrementada.
EP1571199A3 (de)	2006-01-11	Reinigungsmittel enthaltend mehrfach substituierte protease Varianten
ATE116365T1 (de)	1995-01-15	Mutante einer nicht menschlichen carbonyl- hydrolase, für diese kodierende dns-sequenzen und vektoren und durch diese vektoren transformierte wirte.
MY113806A (en)	2002-05-31	Antiparasitic marcfortines and paraherquamides
CA2111645A1 (en)	1994-06-18	Fibrinogen fragment e peptides and antibodies thereto
ES2140082T3 (es)	2000-02-16	Composiciones peptidicas con actividad de tipo factor de crecimiento.
CA2214395A1 (en)	1996-09-19	Proteinase k variants having decreased adsorption and increased hydrolysis
CA2214579A1 (en)	1996-09-19	Subtilisin dy variants having decreased adsorption and increased hydrolysis
EP1006126A3 (de)	2000-10-25	Peptide mit osteogener Aktivität
DK0722457T3 (da)	2002-04-22	Forbindelser, der modificerer den serotoninerge transmission, og diagnostisk og terapeutisk anvendelse af sådanne forbindelser
DE69722618D1 (en)	2003-07-10	Peptide
CA2166692A1 (en)	1995-02-02	Novel 9-n-bicyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines
NZ303588A (en)	1999-02-25	Mpl ligand analogs having one or more changed glycosylation sites uses for these ligand analogs and dna sequences encoding them
MX9706846A (es)	1997-11-29	Variantes de termitasa que tienen adsorcion reducida e hidrolisis incrementada.
CA2077606A1 (en)	1993-04-10	Inhibited 141b
ATE215123T1 (de)	2002-04-15	Or-1, ein wais-rezeptor der nuklearen rezeptoren familie
AU7655994A (en)	1995-03-22	Cloning of a member of the serine-threonine-kinase family
ATE86260T1 (de)	1993-03-15	Peptid-molekuele, wirksam gegen gram-positive keime.
TH17162A (th)	1995-12-14	สารผสมฟอกจากที่ประกอบด้วยเอนไซม์โพรทีเอส