ATE213410T1 - Diclofenac/gamma-cyclodextrin klathrat komponente - Google Patents
Diclofenac/gamma-cyclodextrin klathrat komponenteInfo
- Publication number
- ATE213410T1 ATE213410T1 AT97919309T AT97919309T ATE213410T1 AT E213410 T1 ATE213410 T1 AT E213410T1 AT 97919309 T AT97919309 T AT 97919309T AT 97919309 T AT97919309 T AT 97919309T AT E213410 T1 ATE213410 T1 AT E213410T1
- Authority
- AT
- Austria
- Prior art keywords
- diclofenac
- pct
- gamma
- date
- cyclodextrin
- Prior art date
Links
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001259 diclofenac Drugs 0.000 title abstract 3
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 title abstract 2
- 229940080345 gamma-cyclodextrin Drugs 0.000 title abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229940126701 oral medication Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nanotechnology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Crystallography & Structural Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9600758A HUP9600758A2 (en) | 1996-03-27 | 1996-03-27 | Diclofenac composition of diminished gastrointestinal irritation and enhanced biological resorption |
| PCT/EP1997/001595 WO1997035568A2 (en) | 1996-03-27 | 1997-03-27 | Diclofenac/gamma-cyclodextrin inclusion compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE213410T1 true ATE213410T1 (de) | 2002-03-15 |
Family
ID=89993834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97919309T ATE213410T1 (de) | 1996-03-27 | 1997-03-27 | Diclofenac/gamma-cyclodextrin klathrat komponente |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6071964A (de) |
| EP (1) | EP0893994B1 (de) |
| JP (1) | JP2000507258A (de) |
| CN (1) | CN1217658A (de) |
| AT (1) | ATE213410T1 (de) |
| AU (1) | AU713902B2 (de) |
| BR (1) | BR9708280A (de) |
| CA (1) | CA2250009A1 (de) |
| DE (1) | DE69710574D1 (de) |
| HU (1) | HUP9600758A2 (de) |
| PL (1) | PL329036A1 (de) |
| WO (1) | WO1997035568A2 (de) |
| ZA (1) | ZA972707B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2379854B (en) * | 2001-09-19 | 2006-04-19 | Walcom Animal Science | Dairy cow feed and the use thereof |
| WO2003049753A1 (en) * | 2001-12-13 | 2003-06-19 | Council Of Scientific And Industrial Research | Bioavailability enhancing activity of zingiber officinale linn and its extracts/fractions thereof |
| US20090215735A1 (en) * | 2002-02-25 | 2009-08-27 | Alcon, Inc. | Topical solution formulations containing a corticosteroid and a cyclodextrin |
| CN1232539C (zh) * | 2002-05-10 | 2005-12-21 | 刘云清 | 有机药物与倍他环糊精衍生物的配合物及其制备方法 |
| US20070232567A1 (en) * | 2006-03-28 | 2007-10-04 | Curtis Wright | Formulations Of Low Dose Non-Steroidal Anti-Inflammatory Drugs And Beta-Cyclodextrin |
| CN101410123A (zh) | 2006-03-28 | 2009-04-15 | 杰佛林制药公司 | 低剂量的双氯芬酸和β－环糊精的制剂 |
| JP2009196922A (ja) * | 2008-02-21 | 2009-09-03 | Glovia:Kk | 徐放性フェルラ酸製剤 |
| EP2254555A4 (de) * | 2008-02-27 | 2013-10-09 | Reddys Lab Ltd Dr | Aprepitantformen mit erhöhter löslichkeit und pharmazeutische zusammensetzungen daraus |
| EP2422818A3 (de) * | 2010-08-27 | 2013-01-16 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Verfahren zur Herstellung eines Diclofenac-Cyclodextrin Konjugates |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5984821A (ja) * | 1982-11-04 | 1984-05-16 | Teikoku Chem Ind Corp Ltd | 徐溶化組成物 |
| IT1227626B (it) * | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| IT1241417B (it) * | 1990-03-06 | 1994-01-14 | Vectorpharma Int | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione |
| IT1243342B (it) * | 1990-07-13 | 1994-06-10 | Farcon Ag | Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria |
| IT1247529B (it) * | 1991-04-24 | 1994-12-17 | Poli Ind Chimica Spa | Composizioni farmaceutiche in forma di schiuma per somministrazione intravaginale, cutanea e orale |
| DE69231457T2 (de) * | 1991-06-21 | 2001-05-23 | Takeda Chemical Industries Ltd | Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate |
| DE4207922A1 (de) * | 1992-03-13 | 1993-09-23 | Pharmatech Gmbh | Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung |
| JPH08511009A (ja) * | 1993-06-08 | 1996-11-19 | チバ−ガイギー アクチェンゲゼルシャフト | ジクロフェナックを含有する経口固体剤形の製造方法 |
| IT1264696B1 (it) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
| IL111184A (en) * | 1993-10-08 | 2000-08-13 | Farmarc Nederland B V Of Cito | Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin |
| ZA949182B (en) * | 1993-12-02 | 1995-07-26 | South African Druggists Ltd | Pharmaceutical composition |
-
1996
- 1996-03-27 HU HU9600758A patent/HUP9600758A2/hu unknown
-
1997
- 1997-03-27 ZA ZA9702707A patent/ZA972707B/xx unknown
- 1997-03-27 WO PCT/EP1997/001595 patent/WO1997035568A2/en not_active Ceased
- 1997-03-27 AU AU23829/97A patent/AU713902B2/en not_active Ceased
- 1997-03-27 PL PL97329036A patent/PL329036A1/xx unknown
- 1997-03-27 US US09/155,298 patent/US6071964A/en not_active Expired - Fee Related
- 1997-03-27 BR BR9708280A patent/BR9708280A/pt unknown
- 1997-03-27 CN CN97194134A patent/CN1217658A/zh active Pending
- 1997-03-27 AT AT97919309T patent/ATE213410T1/de not_active IP Right Cessation
- 1997-03-27 EP EP97919309A patent/EP0893994B1/de not_active Expired - Lifetime
- 1997-03-27 JP JP9534053A patent/JP2000507258A/ja active Pending
- 1997-03-27 CA CA002250009A patent/CA2250009A1/en not_active Abandoned
- 1997-03-27 DE DE69710574T patent/DE69710574D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1217658A (zh) | 1999-05-26 |
| EP0893994A2 (de) | 1999-02-03 |
| HUP9600758A2 (en) | 1998-03-02 |
| DE69710574D1 (de) | 2002-03-28 |
| CA2250009A1 (en) | 1997-10-02 |
| PL329036A1 (en) | 1999-03-01 |
| WO1997035568A3 (en) | 1997-12-04 |
| JP2000507258A (ja) | 2000-06-13 |
| WO1997035568A2 (en) | 1997-10-02 |
| EP0893994B1 (de) | 2002-02-20 |
| AU713902B2 (en) | 1999-12-16 |
| BR9708280A (pt) | 1999-08-03 |
| HU9600758D0 (en) | 1996-05-28 |
| US6071964A (en) | 2000-06-06 |
| ZA972707B (en) | 1997-10-22 |
| AU2382997A (en) | 1997-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |