ATE213742T1 - Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität - Google Patents

Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität

Info

Publication number
ATE213742T1
ATE213742T1 AT96927035T AT96927035T ATE213742T1 AT E213742 T1 ATE213742 T1 AT E213742T1 AT 96927035 T AT96927035 T AT 96927035T AT 96927035 T AT96927035 T AT 96927035T AT E213742 T1 ATE213742 T1 AT E213742T1
Authority
AT
Austria
Prior art keywords
growth hormone
inhibiting activity
pct
somatostatin analogs
cyclic somatostatin
Prior art date
Application number
AT96927035T
Other languages
English (en)
Inventor
Romano Deghenghi
Original Assignee
Romano Deghenghi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romano Deghenghi filed Critical Romano Deghenghi
Application granted granted Critical
Publication of ATE213742T1 publication Critical patent/ATE213742T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT96927035T 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität ATE213742T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001670A IT1277391B1 (it) 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita
PCT/EP1996/003149 WO1997005167A1 (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone

Publications (1)

Publication Number Publication Date
ATE213742T1 true ATE213742T1 (de) 2002-03-15

Family

ID=11372091

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96927035T ATE213742T1 (de) 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität

Country Status (14)

Country Link
US (1) US5962409A (de)
EP (1) EP0842193B1 (de)
JP (1) JPH11510147A (de)
KR (1) KR100321448B1 (de)
AT (1) ATE213742T1 (de)
AU (1) AU6700996A (de)
BR (1) BR9609801A (de)
CA (1) CA2227980A1 (de)
DE (1) DE69619530T2 (de)
DK (1) DK0842193T3 (de)
ES (1) ES2171704T3 (de)
IT (1) IT1277391B1 (de)
PT (1) PT842193E (de)
WO (1) WO1997005167A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579967B1 (en) 1999-12-14 2003-06-17 The Salk Institute For Biological Studies Receptor-selective somatostatin analogs
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
CN1317031C (zh) * 2005-09-14 2007-05-23 上海第二医科大学附属新华医院 增强实体肿瘤细胞化疗敏感性的高效混合制剂
PT2275103E (pt) 2005-11-21 2014-07-24 Novartis Ag Inibidores de mtor para o tratamento de tumores endócrinos
WO2013032012A1 (ja) * 2011-09-04 2013-03-07 株式会社糖鎖工学研究所 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
EP0588905A1 (de) * 1991-06-03 1994-03-30 Mallinckrodt Medical, Inc. Radioaktiv markierte somatostatinderivate, ihre herstellung und verwendung
JPH07500259A (ja) * 1991-06-06 1995-01-12 ソマネチックス　コーポレイション 光学式大脳酸素濃度計

Also Published As

Publication number Publication date
ES2171704T3 (es) 2002-09-16
BR9609801A (pt) 1999-07-06
US5962409A (en) 1999-10-05
KR19990035961A (ko) 1999-05-25
IT1277391B1 (it) 1997-11-10
PT842193E (pt) 2002-06-28
DK0842193T3 (da) 2002-04-29
WO1997005167A1 (en) 1997-02-13
ITMI951670A0 (it) 1995-07-28
DE69619530T2 (de) 2002-08-08
KR100321448B1 (ko) 2002-07-31
CA2227980A1 (en) 1997-02-13
AU6700996A (en) 1997-02-26
ITMI951670A1 (it) 1997-01-28
HK1008225A1 (en) 1999-05-07
JPH11510147A (ja) 1999-09-07
DE69619530D1 (de) 2002-04-04
EP0842193B1 (de) 2002-02-27
EP0842193A1 (de) 1998-05-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee