ATE216690T1 - Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten - Google Patents
Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivatenInfo
- Publication number
- ATE216690T1 ATE216690T1 AT97930607T AT97930607T ATE216690T1 AT E216690 T1 ATE216690 T1 AT E216690T1 AT 97930607 T AT97930607 T AT 97930607T AT 97930607 T AT97930607 T AT 97930607T AT E216690 T1 ATE216690 T1 AT E216690T1
- Authority
- AT
- Austria
- Prior art keywords
- asymmetric hydrogenation
- pct
- derivative
- derivatives
- compound
- Prior art date
Links
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- -1 KETONE COMPOUNDS Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- VURFVHCLMJOLKN-UHFFFAOYSA-N diphosphane Chemical compound PP VURFVHCLMJOLKN-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000004696 coordination complex Chemical class 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
- C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9608060A FR2750423B1 (fr) | 1996-06-28 | 1996-06-28 | Procede d'hydrogenation asymetrique d'un compose cetonique |
| PCT/FR1997/001154 WO1998000375A1 (fr) | 1996-06-28 | 1997-06-27 | Procede d'hydrogenation asymetrique d'un compose cetonique et derive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE216690T1 true ATE216690T1 (de) | 2002-05-15 |
Family
ID=9493517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97930607T ATE216690T1 (de) | 1996-06-28 | 1997-06-27 | Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6166257A (de) |
| EP (1) | EP0912467B1 (de) |
| JP (1) | JP2000513370A (de) |
| AT (1) | ATE216690T1 (de) |
| DE (1) | DE69712204T2 (de) |
| ES (1) | ES2173460T3 (de) |
| FR (1) | FR2750423B1 (de) |
| NO (1) | NO312363B1 (de) |
| WO (1) | WO1998000375A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743921B2 (en) * | 2002-01-24 | 2004-06-01 | Dsm Catalytica Pharmaceuticals, Inc. | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds |
| US20040030199A1 (en) * | 2002-01-29 | 2004-02-12 | Maughon Robert R. | Process for reducing alpha-haloketones to secondary alpha-haloalcohols |
| PT2361924E (pt) | 2004-09-09 | 2014-03-13 | Teva Pharma | Processo para a preparação de misturas de acetato de glatirâmero trifluoroacetiílico utilizando ácido bromídrico purificado |
| EP2009776A1 (de) * | 2007-06-26 | 2008-12-31 | Austriamicrosystems AG | Auf- und Abwärtstaktregler und zugehöriges Verfahren |
| BRPI0907343A8 (pt) * | 2008-04-17 | 2017-05-23 | United Phosphorus Ltd | Hidrogenação de iminas |
| WO2010032136A1 (en) | 2008-09-19 | 2010-03-25 | University Technologies International | Expeditious synthesis of gibberllin a5 and esters thereof |
| US8410176B2 (en) | 2009-12-29 | 2013-04-02 | Mapi Pharma Ltd. | Intermediate compounds and processes for the preparation of tapentadol and related compounds |
| US9614443B2 (en) | 2014-07-24 | 2017-04-04 | Qorvo Us, Inc. | Smooth transitioning buck-boost DC-DC converter |
| US11427543B2 (en) | 2016-07-19 | 2022-08-30 | The General Hospital Corporation | Compounds for targeting cancer stem cells |
| ES2933278T3 (es) | 2018-05-01 | 2023-02-03 | Dow Global Technologies Llc | Concentrados emulsionables |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758107A (nl) * | 1969-11-05 | 1971-04-28 | Shell Int Research | Werkwijze ter bereiding van 9-carboxymethyl- 9- fosfabicyclononanen en alkalimetaalzouten daarvan |
| US4996361A (en) * | 1987-07-30 | 1991-02-26 | The University Of British Columbia | Process for the preparation of optically active secondary arylamines |
| DE4001019A1 (de) * | 1990-01-16 | 1991-07-18 | Degussa | Verfahren zur asymmetrischen hydrierung von (alpha)-ketocarbonylverbindungen zu optisch aktiven (alpha)-hydroxycarbonylverbindungen |
| US5250731A (en) * | 1992-03-17 | 1993-10-05 | E. I. Du Pont De Nemours And Company | Preparation of optically active hydrazines and amines |
| FR2693190B1 (fr) * | 1992-07-02 | 1994-09-23 | Elf Aquitaine | Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO. |
| DK0647648T3 (da) * | 1993-10-08 | 1999-09-27 | Hoffmann La Roche | Optisk aktive phosphorforbindelser |
| RU2150464C1 (ru) * | 1994-02-02 | 2000-06-10 | Новартис Аг | Способ гидрогенизации иминов и способ получения амина |
| WO1996020202A1 (fr) * | 1994-12-28 | 1996-07-04 | Rhone-Poulenc Chimie | Diphosphines optiquement actives, leur preparation par dedoublement du melange racemique |
| DE19620023C2 (de) * | 1996-05-17 | 2001-03-08 | Celanese Chem Europe Gmbh | Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane |
| EP0810903B1 (de) * | 1995-11-22 | 1999-05-26 | Firmenich Sa | Rutheniumkatalysatoren und deren verwendung zur asymmetrischen cyclopentenonhydrierung |
-
1996
- 1996-06-28 FR FR9608060A patent/FR2750423B1/fr not_active Expired - Fee Related
-
1997
- 1997-06-27 DE DE69712204T patent/DE69712204T2/de not_active Expired - Fee Related
- 1997-06-27 JP JP10503880A patent/JP2000513370A/ja active Pending
- 1997-06-27 EP EP97930607A patent/EP0912467B1/de not_active Expired - Lifetime
- 1997-06-27 ES ES97930607T patent/ES2173460T3/es not_active Expired - Lifetime
- 1997-06-27 WO PCT/FR1997/001154 patent/WO1998000375A1/fr not_active Ceased
- 1997-06-27 US US09/202,665 patent/US6166257A/en not_active Expired - Fee Related
- 1997-06-27 AT AT97930607T patent/ATE216690T1/de not_active IP Right Cessation
-
1998
- 1998-12-23 NO NO19986124A patent/NO312363B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0912467A1 (de) | 1999-05-06 |
| DE69712204T2 (de) | 2002-11-21 |
| NO986124D0 (no) | 1998-12-23 |
| NO312363B1 (no) | 2002-04-29 |
| US6166257A (en) | 2000-12-26 |
| WO1998000375A1 (fr) | 1998-01-08 |
| JP2000513370A (ja) | 2000-10-10 |
| FR2750423B1 (fr) | 1998-08-14 |
| FR2750423A1 (fr) | 1998-01-02 |
| DE69712204D1 (de) | 2002-05-29 |
| ES2173460T3 (es) | 2002-10-16 |
| NO986124L (no) | 1999-03-01 |
| EP0912467B1 (de) | 2002-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |