ATE216690T1 - Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten - Google Patents

Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten

Info

Publication number
ATE216690T1
ATE216690T1 AT97930607T AT97930607T ATE216690T1 AT E216690 T1 ATE216690 T1 AT E216690T1 AT 97930607 T AT97930607 T AT 97930607T AT 97930607 T AT97930607 T AT 97930607T AT E216690 T1 ATE216690 T1 AT E216690T1
Authority
AT
Austria
Prior art keywords
asymmetric hydrogenation
pct
derivative
derivatives
compound
Prior art date
Application number
AT97930607T
Other languages
English (en)
Inventor
Francois Mathey
Frederic Robin
Francois Mercier
Michel Spagnol
Original Assignee
Rhodia Chimie Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Chimie Sa filed Critical Rhodia Chimie Sa
Application granted granted Critical
Publication of ATE216690T1 publication Critical patent/ATE216690T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT97930607T 1996-06-28 1997-06-27 Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten ATE216690T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9608060A FR2750423B1 (fr) 1996-06-28 1996-06-28 Procede d'hydrogenation asymetrique d'un compose cetonique
PCT/FR1997/001154 WO1998000375A1 (fr) 1996-06-28 1997-06-27 Procede d'hydrogenation asymetrique d'un compose cetonique et derive

Publications (1)

Publication Number Publication Date
ATE216690T1 true ATE216690T1 (de) 2002-05-15

Family

ID=9493517

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97930607T ATE216690T1 (de) 1996-06-28 1997-06-27 Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten

Country Status (9)

Country Link
US (1) US6166257A (de)
EP (1) EP0912467B1 (de)
JP (1) JP2000513370A (de)
AT (1) ATE216690T1 (de)
DE (1) DE69712204T2 (de)
ES (1) ES2173460T3 (de)
FR (1) FR2750423B1 (de)
NO (1) NO312363B1 (de)
WO (1) WO1998000375A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743921B2 (en) * 2002-01-24 2004-06-01 Dsm Catalytica Pharmaceuticals, Inc. Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds
US20040030199A1 (en) * 2002-01-29 2004-02-12 Maughon Robert R. Process for reducing alpha-haloketones to secondary alpha-haloalcohols
PT2361924E (pt) 2004-09-09 2014-03-13 Teva Pharma Processo para a preparação de misturas de acetato de glatirâmero trifluoroacetiílico utilizando ácido bromídrico purificado
EP2009776A1 (de) * 2007-06-26 2008-12-31 Austriamicrosystems AG Auf- und Abwärtstaktregler und zugehöriges Verfahren
BRPI0907343A8 (pt) * 2008-04-17 2017-05-23 United Phosphorus Ltd Hidrogenação de iminas
WO2010032136A1 (en) 2008-09-19 2010-03-25 University Technologies International Expeditious synthesis of gibberllin a5 and esters thereof
US8410176B2 (en) 2009-12-29 2013-04-02 Mapi Pharma Ltd. Intermediate compounds and processes for the preparation of tapentadol and related compounds
US9614443B2 (en) 2014-07-24 2017-04-04 Qorvo Us, Inc. Smooth transitioning buck-boost DC-DC converter
US11427543B2 (en) 2016-07-19 2022-08-30 The General Hospital Corporation Compounds for targeting cancer stem cells
ES2933278T3 (es) 2018-05-01 2023-02-03 Dow Global Technologies Llc Concentrados emulsionables

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758107A (nl) * 1969-11-05 1971-04-28 Shell Int Research Werkwijze ter bereiding van 9-carboxymethyl- 9- fosfabicyclononanen en alkalimetaalzouten daarvan
US4996361A (en) * 1987-07-30 1991-02-26 The University Of British Columbia Process for the preparation of optically active secondary arylamines
DE4001019A1 (de) * 1990-01-16 1991-07-18 Degussa Verfahren zur asymmetrischen hydrierung von (alpha)-ketocarbonylverbindungen zu optisch aktiven (alpha)-hydroxycarbonylverbindungen
US5250731A (en) * 1992-03-17 1993-10-05 E. I. Du Pont De Nemours And Company Preparation of optically active hydrazines and amines
FR2693190B1 (fr) * 1992-07-02 1994-09-23 Elf Aquitaine Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO.
DK0647648T3 (da) * 1993-10-08 1999-09-27 Hoffmann La Roche Optisk aktive phosphorforbindelser
RU2150464C1 (ru) * 1994-02-02 2000-06-10 Новартис Аг Способ гидрогенизации иминов и способ получения амина
WO1996020202A1 (fr) * 1994-12-28 1996-07-04 Rhone-Poulenc Chimie Diphosphines optiquement actives, leur preparation par dedoublement du melange racemique
DE19620023C2 (de) * 1996-05-17 2001-03-08 Celanese Chem Europe Gmbh Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane
EP0810903B1 (de) * 1995-11-22 1999-05-26 Firmenich Sa Rutheniumkatalysatoren und deren verwendung zur asymmetrischen cyclopentenonhydrierung

Also Published As

Publication number Publication date
EP0912467A1 (de) 1999-05-06
DE69712204T2 (de) 2002-11-21
NO986124D0 (no) 1998-12-23
NO312363B1 (no) 2002-04-29
US6166257A (en) 2000-12-26
WO1998000375A1 (fr) 1998-01-08
JP2000513370A (ja) 2000-10-10
FR2750423B1 (fr) 1998-08-14
FR2750423A1 (fr) 1998-01-02
DE69712204D1 (de) 2002-05-29
ES2173460T3 (es) 2002-10-16
NO986124L (no) 1999-03-01
EP0912467B1 (de) 2002-04-24

Similar Documents

Publication Publication Date Title
ATE216690T1 (de) Verfahren zur asymmetrischen hydrierung von ketonverbindungen und ihren derivaten
DE59309554D1 (de) Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
ATE198983T1 (de) Verfahren zur inhibierung von aldh-i zur behandlung von alkoholabhaengigkeit oder- missbrauch
ES2123910T3 (es) Composiciones que contienen sales anfoteras de alfa-hidroxiacidos y monocaprilato de glicerol.
DE59900903D1 (de) Katalysator, umfassend einen komplex eines metalls der viii. nebengruppe auf basis eines zweizähnigen phosphonitliganden und verfahren zur herstellung von nitrilen
ATE226953T1 (de) 3-,8-substituierte deuteroporphyrinderivate, diese enthaltende pharmazeutische mittel und verfahren zu ihrer herstellung
DE59500517D1 (de) Mittel zur steigerung der haltbarkeit von schlachttierkörpern
ATE153649T1 (de) Arylpropionsäurederivat, verfahren zu seiner herstellung und seine verwendung als analgetikum
NO972155D0 (no) Fremgangsmåte og opplösning for dannelse av et konversjonsbelegg på en metalloverflate
DK0989973T3 (da) Chalconer med antiproliferativ aktivitet
ATE190843T1 (de) Zubereitungen zur behandlung von impotenz, die ein alpha-1 inhibitor und ein alpha-2 inhibitor enthalten
DE69307706D1 (de) Verfahren zur enantioselektiven hydrierung der carbonylgruppe unter verwendung von ruthenium komplexen mit biphosphineliganden
MD902B2 (ro) Procedeu de obţinere a benzenilor substituiţi, a acidului sulfobenzenic, a derivaţilor lor şi peocedeu de obţinere a N, N'-urelori substituite
ATE211479T1 (de) Chirale ferrocene
ATE259239T1 (de) Trockenextrakt aus der hennapflanze, verfahren zu dessen herstellung und dessen verwendung
ATE70821T1 (de) Verfahren zur herstellung von aldehyd- oder ketonverbindungen sowie nach diesem verfahren erhaltene aldehyde und ketone.
ATE229819T1 (de) Pseudopolyrotaxane
ATE203162T1 (de) Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4- aza-5 alpha-androst-1-en-3-one
DE69004041D1 (de) Verfahren für die Behandlung von neuem oder gebrauchtem Graphitpulver zur Verbesserung seiner Effektivität als Träger für katalytische Metalle.
ATE128871T1 (de) Verfahren zur behandlung von thrombocytopenie und dafür geeignete pharmazeutische zusammensetzungen.
DE59704392D1 (de) Verfahren zur hydroformylierung von olefinen im zweiphasensystem
ATE215368T1 (de) Verwendung von forskolin oder diese enthaltende extrakte zur herstellung eines medikaments für die behandlung von alkoholsucht
BR9711744A (pt) Processo de prepara-Æo de um lcool opticamente ativo
DE59706904D1 (de) Verfahren zur herstellung von ivermectin
DE69808607D1 (de) Verfahren zur verwendung von cyclooxygenase-2 hemmern zur behandlung und vorbeugung der demenz

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee