ATE217906T1 - Methoden zur zielrichtung von dna - Google Patents
Methoden zur zielrichtung von dnaInfo
- Publication number
- ATE217906T1 ATE217906T1 AT92901270T AT92901270T ATE217906T1 AT E217906 T1 ATE217906 T1 AT E217906T1 AT 92901270 T AT92901270 T AT 92901270T AT 92901270 T AT92901270 T AT 92901270T AT E217906 T1 ATE217906 T1 AT E217906T1
- Authority
- AT
- Austria
- Prior art keywords
- dna molecule
- stranded dna
- strand
- double
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000008685 targeting Effects 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 8
- 102000053602 DNA Human genes 0.000 abstract 8
- 108020004682 Single-Stranded DNA Proteins 0.000 abstract 2
- 230000000295 complement effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000005215 recombination Methods 0.000 abstract 1
- 230000006798 recombination Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
- C12N2310/153—Nucleic acids forming more than 2 strands, e.g. TFOs with the aid of a protein, e.g. recombinase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61126890A | 1990-11-09 | 1990-11-09 | |
| US73374491A | 1991-07-24 | 1991-07-24 | |
| PCT/US1991/008200 WO1992008791A1 (en) | 1990-11-09 | 1991-11-08 | Method of targeting dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE217906T1 true ATE217906T1 (de) | 2002-06-15 |
Family
ID=27086477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92901270T ATE217906T1 (de) | 1990-11-09 | 1991-11-08 | Methoden zur zielrichtung von dna |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5460941A (de) |
| EP (1) | EP0556330B1 (de) |
| JP (1) | JP2739378B2 (de) |
| AT (1) | ATE217906T1 (de) |
| AU (1) | AU658386B2 (de) |
| CA (1) | CA2095624C (de) |
| DE (1) | DE69133018T2 (de) |
| WO (1) | WO1992008791A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020108136A1 (en) * | 1997-03-21 | 2002-08-08 | Sri | Transgenic animals produced by homologous sequence targeting |
| AU4115693A (en) * | 1992-04-24 | 1993-11-29 | Sri International | In vivo homologous sequence targeting in eukaryotic cells |
| US5861244A (en) * | 1992-10-29 | 1999-01-19 | Profile Diagnostic Sciences, Inc. | Genetic sequence assay using DNA triple strand formation |
| US5731411A (en) * | 1993-07-12 | 1998-03-24 | The United States Of America As Represented By The Department Of Health And Human Services | Promotion of homologous DNA pairing by RecA-derived peptides |
| WO1995009236A1 (en) * | 1993-09-28 | 1995-04-06 | The General Hospital Corporation | USING ANTISENSE OLIGONUCLEOTIDES TO MODULATE NERVE GROWTH AND TO REVERSE β/A4 AMYLOID-INDUCED MORPHOLOGY |
| US5965361A (en) * | 1993-12-28 | 1999-10-12 | Daikin Industries, Ltd. | In-situ hybridization method using RecA protein and RecA protein having marker or ligand for use in said method |
| US5780296A (en) * | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
| US5776744A (en) * | 1995-06-07 | 1998-07-07 | Yale University | Methods and compositions for effecting homologous recombination |
| JPH11509423A (ja) * | 1995-07-21 | 1999-08-24 | ザ ガヴァメント オヴ ザ ユナイテッド ステイツ オヴ アメリカ、リプレゼンティッド バイ ザ セクレタリー、ディパートメント オヴ ヘルス アンド ヒューマン サーヴィスィーズ | Ｒｅｃ支援ＤＮＡクローニング |
| JPH11513887A (ja) * | 1995-10-27 | 1999-11-30 | ランバーグ，エリオット，アール． | 特定のヌクレオチド配列の検出方法および組成物 |
| FR2757537B1 (fr) * | 1996-12-23 | 1999-03-19 | Genset Sa | Procede destine a l'elimination de sequences specifiques lors de la production de banques d'adn |
| US5948653A (en) | 1997-03-21 | 1999-09-07 | Pati; Sushma | Sequence alterations using homologous recombination |
| JPH11151100A (ja) * | 1997-11-19 | 1999-06-08 | Aisin Cosmos Kenkyusho:Kk | プローブによる核酸の検出方法 |
| WO1999037755A2 (en) * | 1997-12-11 | 1999-07-29 | Pangene Corporation | The use of consensus sequences for targeted homologous gene isolation and recombination in gene families |
| NL1009369C2 (nl) * | 1998-06-10 | 1999-12-13 | Stichting Tech Wetenschapp | Werkwijze voor het onderdrukken van de expressie van een gen. |
| JP4265028B2 (ja) * | 1999-04-14 | 2009-05-20 | アイシン精機株式会社 | 二本鎖ｄｎａの特異的切断方法およびそのためのキット |
| JP4465741B2 (ja) * | 1999-07-02 | 2010-05-19 | アイシン精機株式会社 | 二本鎖ｄｎａ断片の末端での連結 |
| US7045314B2 (en) * | 2000-04-04 | 2006-05-16 | Baxter International Inc. | Method for the production of bacterial toxins |
| US6686180B2 (en) * | 2000-04-04 | 2004-02-03 | Baxter International Inc. | Method for the production of bacterial toxins |
| US20020132350A1 (en) * | 2000-09-14 | 2002-09-19 | Pioneer Hi-Bred International, Inc. | Targeted genetic manipulation using Mu bacteriophage cleaved donor complex |
| JP4681129B2 (ja) * | 2001-01-19 | 2011-05-11 | 株式会社アイシン・コスモス研究所 | 核酸末端領域の非対称的修飾法 |
| EP1414840A4 (de) | 2001-03-27 | 2005-04-13 | Univ Delaware | Genomics-anwendungen für modifizierte oligonukleotide |
| US7468244B2 (en) | 2001-09-27 | 2008-12-23 | University Of Delaware | Polymorphism detection and separation |
| WO2003089587A2 (en) * | 2002-04-16 | 2003-10-30 | Promega Corporation | Method to enhance homologous recombination |
| JP4278412B2 (ja) | 2003-03-13 | 2009-06-17 | 株式会社アイシン・コスモス研究所 | 部分的なｄｎａ鎖の相同的組換えによる遺伝子除去方法および遺伝子取得方法 |
| CA2541177A1 (en) * | 2003-10-03 | 2005-09-22 | Promega Corporation | Vectors for directional cloning |
| US8293503B2 (en) | 2003-10-03 | 2012-10-23 | Promega Corporation | Vectors for directional cloning |
| EP3985125A1 (de) | 2004-06-01 | 2022-04-20 | Abbott Diagnostics Scarborough, Inc. | Rekombinase-polymerase-verstärkung |
| WO2016178207A1 (en) * | 2015-05-04 | 2016-11-10 | Ramot At Tel-Aviv University Ltd. | Methods and kits for fragmenting dna |
| CN110506203A (zh) | 2017-04-07 | 2019-11-26 | 塞奇科学股份有限公司 | 用于通过使用集成电泳dna纯化来检测遗传结构变异的系统和方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888274A (en) * | 1985-09-18 | 1989-12-19 | Yale University | RecA nucleoprotein filament and methods |
-
1991
- 1991-11-08 AT AT92901270T patent/ATE217906T1/de not_active IP Right Cessation
- 1991-11-08 WO PCT/US1991/008200 patent/WO1992008791A1/en not_active Ceased
- 1991-11-08 JP JP4501512A patent/JP2739378B2/ja not_active Expired - Fee Related
- 1991-11-08 EP EP92901270A patent/EP0556330B1/de not_active Expired - Lifetime
- 1991-11-08 CA CA002095624A patent/CA2095624C/en not_active Expired - Fee Related
- 1991-11-08 AU AU91116/91A patent/AU658386B2/en not_active Ceased
- 1991-11-08 DE DE69133018T patent/DE69133018T2/de not_active Expired - Fee Related
-
1993
- 1993-07-12 US US08/089,910 patent/US5460941A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0556330B1 (de) | 2002-05-22 |
| EP0556330A1 (de) | 1993-08-25 |
| AU658386B2 (en) | 1995-04-13 |
| CA2095624A1 (en) | 1992-05-10 |
| CA2095624C (en) | 2000-06-13 |
| US5460941A (en) | 1995-10-24 |
| JPH06500926A (ja) | 1994-01-27 |
| EP0556330A4 (en) | 1995-02-08 |
| JP2739378B2 (ja) | 1998-04-15 |
| DE69133018T2 (de) | 2003-01-02 |
| WO1992008791A1 (en) | 1992-05-29 |
| AU9111691A (en) | 1992-06-11 |
| DE69133018D1 (de) | 2002-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |