ATE218133T1 - Verfahren zum ausgewähltem schutz von baccatinderivaten und ihre verwendung für die synthese von taxanen - Google Patents

Verfahren zum ausgewähltem schutz von baccatinderivaten und ihre verwendung für die synthese von taxanen

Info

Publication number
ATE218133T1
ATE218133T1 AT96944097T AT96944097T ATE218133T1 AT E218133 T1 ATE218133 T1 AT E218133T1 AT 96944097 T AT96944097 T AT 96944097T AT 96944097 T AT96944097 T AT 96944097T AT E218133 T1 ATE218133 T1 AT E218133T1
Authority
AT
Austria
Prior art keywords
derivatives
taxans
baccatine
synthesis
selected protection
Prior art date
Application number
AT96944097T
Other languages
English (en)
Inventor
Luc Chanteloup
Bruno Chauveau
Christine Corbin
Robert Dhal
Guen Sonia Le
Arnaud Lamy
Antoine Leze
Jean-Pierre Robin
Original Assignee
Seripharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seripharm filed Critical Seripharm
Application granted granted Critical
Publication of ATE218133T1 publication Critical patent/ATE218133T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT96944097T 1995-12-27 1996-12-27 Verfahren zum ausgewähltem schutz von baccatinderivaten und ihre verwendung für die synthese von taxanen ATE218133T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9515557A FR2743074B1 (fr) 1995-12-27 1995-12-27 Procede de protection selective des derives de la baccatine et son utilisation dans la synthese des taxanes
PCT/FR1996/002097 WO1997024345A1 (fr) 1995-12-27 1996-12-27 Procede de protection selective des derives de la baccatine et son utilisation dans la synthese des taxanes

Publications (1)

Publication Number Publication Date
ATE218133T1 true ATE218133T1 (de) 2002-06-15

Family

ID=9486008

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96944097T ATE218133T1 (de) 1995-12-27 1996-12-27 Verfahren zum ausgewähltem schutz von baccatinderivaten und ihre verwendung für die synthese von taxanen

Country Status (25)

Country Link
US (1) US6180802B1 (de)
EP (1) EP0889885B1 (de)
JP (1) JP4068663B2 (de)
KR (1) KR100510017B1 (de)
CN (3) CN1243745C (de)
AT (1) ATE218133T1 (de)
AU (1) AU716876B2 (de)
BR (1) BR9612242A (de)
CA (1) CA2238889C (de)
CZ (1) CZ20191998A3 (de)
DE (1) DE69621463T2 (de)
DK (1) DK0889885T3 (de)
ES (1) ES2177825T3 (de)
FR (1) FR2743074B1 (de)
HK (2) HK1044765B (de)
HU (1) HUP0000508A3 (de)
IL (2) IL125049A (de)
NO (1) NO982719L (de)
NZ (1) NZ325323A (de)
PL (1) PL327581A1 (de)
PT (1) PT889885E (de)
RU (1) RU2162844C2 (de)
SK (1) SK88498A3 (de)
TR (1) TR199801232T2 (de)
WO (1) WO1997024345A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0875508T1 (en) * 1997-05-02 2004-04-30 Pharmachemie B.V. Method for the preparation of baccatin III and derivatives thereof from 10-deacetylbaccatin III
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
RU2437875C2 (ru) * 2006-03-21 2011-12-27 Др. Редди'С Лабораторис Лтд. Полиморфы доцетаксела и способы их получения
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
CN101835769A (zh) * 2007-08-22 2010-09-15 6570763加拿大有限公司 将9-二氢-13-乙酰基浆果赤霉素ⅲ转化为多烯紫杉醇或太平洋紫杉醇的方法
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
CN115260130A (zh) * 2022-07-07 2022-11-01 上海卓鼎生物技术有限公司 一种10-脱乙酰基紫杉醇的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601676B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
IL127598A (en) * 1994-01-28 2003-04-10 Upjohn Co Process for preparing isotaxol analogs

Also Published As

Publication number Publication date
CN1206412A (zh) 1999-01-27
AU716876B2 (en) 2000-03-09
CA2238889A1 (fr) 1997-07-10
HK1044765A1 (en) 2002-11-01
HUP0000508A2 (en) 2000-07-28
CN1243745C (zh) 2006-03-01
CN1356325A (zh) 2002-07-03
KR19990076733A (ko) 1999-10-15
IL138769A (en) 2006-04-10
NO982719D0 (no) 1998-06-12
SK88498A3 (en) 1998-11-04
CZ20191998A3 (cs) 1998-09-16
TR199801232T2 (xx) 1998-09-21
NO982719L (no) 1998-06-12
HK1047099A1 (en) 2003-02-07
CA2238889C (fr) 2008-06-10
CN1244567C (zh) 2006-03-08
IL125049A (en) 2003-10-31
JP2000502696A (ja) 2000-03-07
PT889885E (pt) 2002-10-31
DK0889885T3 (da) 2002-09-16
US6180802B1 (en) 2001-01-30
HUP0000508A3 (en) 2001-05-28
FR2743074A1 (fr) 1997-07-04
KR100510017B1 (ko) 2005-12-16
RU2162844C2 (ru) 2001-02-10
IL125049A0 (en) 1999-01-26
HK1044765B (zh) 2006-09-29
DE69621463D1 (de) 2002-07-04
NZ325323A (en) 1999-11-29
EP0889885A1 (de) 1999-01-13
CN1090625C (zh) 2002-09-11
CN1356326A (zh) 2002-07-03
HK1047099B (zh) 2006-09-29
EP0889885B1 (de) 2002-05-29
ES2177825T3 (es) 2002-12-16
FR2743074B1 (fr) 1998-03-27
AU1381597A (en) 1997-07-28
JP4068663B2 (ja) 2008-03-26
PL327581A1 (en) 1998-12-21
DE69621463T2 (de) 2002-11-28
WO1997024345A1 (fr) 1997-07-10
BR9612242A (pt) 1999-07-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee