ATE220064T1 - C2-taxan-derivate sowie diese enthaltende arzneimittel - Google Patents

C2-taxan-derivate sowie diese enthaltende arzneimittel

Info

Publication number: ATE220064T1
Authority: AT; Austria
Prior art keywords: products containing; medicinal products; taxan derivatives; derivatives; taxan
Prior art date: 1993-01-29

Application number

AT94907959T

Other languages

English (en)

Inventor

Robert Holton

Chunlin Tao

Original Assignee

Univ Florida State

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-29

Filing date

1994-01-28

Publication date

2002-07-15

1993-01-29 Priority claimed from US08/010,798 external-priority patent/US5399726A/en

1994-01-28 Application filed by Univ Florida State filed Critical Univ Florida State

2002-07-15 Application granted granted Critical

2002-07-15 Publication of ATE220064T1 publication Critical patent/ATE220064T1/de

Links

229940126601 medicinal product Drugs 0.000 title 1
125000001424 substituent group Chemical group 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003368 amide group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 nitro, amino Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

AT94907959T 1993-01-29 1994-01-28 C2-taxan-derivate sowie diese enthaltende arzneimittel ATE220064T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/010,798 US5399726A (en)	1993-01-29	1993-01-29	Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US3485293A	1993-03-22	1993-03-22
US9471593A	1993-07-20	1993-07-20
PCT/US1994/001223 WO1994017052A1 (en)	1993-01-29	1994-01-28	C2 taxane derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
ATE220064T1 true ATE220064T1 (de)	2002-07-15

Family

ID=27359309

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT94907959T ATE220064T1 (de)	1993-01-29	1994-01-28	C2-taxan-derivate sowie diese enthaltende arzneimittel
AT94909517T ATE217870T1 (de)	1993-01-29	1994-01-31	Verfahren zur herstell ung von baccatin iii- analogen, verbindungen mit neuen funktionellen gruppen an c2 und c4

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT94909517T ATE217870T1 (de)	1993-01-29	1994-01-31	Verfahren zur herstell ung von baccatin iii- analogen, verbindungen mit neuen funktionellen gruppen an c2 und c4

Country Status (13)

Country	Link
EP (2)	EP0681573B1 (de)
JP (2)	JP3452928B2 (de)
CN (1)	CN1125061C (de)
AT (2)	ATE220064T1 (de)
AU (2)	AU685778B2 (de)
CA (2)	CA2155013C (de)
DE (2)	DE69430902T2 (de)
DK (1)	DK0681573T3 (de)
ES (1)	ES2176237T3 (de)
IL (1)	IL108444A0 (de)
PT (1)	PT681573E (de)
TW (2)	TW360646B (de)
WO (2)	WO1994017052A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5710287A (en)	1991-09-23	1998-01-20	Florida State University	Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
IL108443A0 (en) *	1993-01-29	1994-04-12	Univ Florida State	C7 taxane derivatives and pharmaceutical compositions containing them
FR2702212B1 (fr) *	1993-03-02	1995-04-07	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5677470A (en) *	1994-06-28	1997-10-14	Tanabe Seiyaku Co., Ltd.	Baccatin derivatives and processes for preparing the same
FR2723094A1 (fr) *	1994-07-26	1996-02-02	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2162759A1 (en) *	1994-11-17	1996-05-18	Kenji Tsujihara	Baccatin derivatives and processes for preparing the same
EP0868422A1 (de) *	1996-09-24	1998-10-07	Marigen S.A.	Ultramikroemulsionen aus spontan dispergierbaren konzentraten mit antitumoral und antiviral wirksamen estern von baccatin-iii-verbindungen
EP1067923A4 (de) *	1997-12-31	2002-11-13	Bristol Myers Squibb Co	2-aroyl-4-acyl paclitaxel (taxol) analoge
ITMI20021921A1 (it) *	2002-09-10	2004-03-11	Indena Spa	Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
KR20070013300A (ko) *	2004-05-14	2007-01-30	이뮤노젠 아이엔씨	박카틴 ⅲ 화합물의 합성 방법
US20130090484A1 (en) *	2011-10-11	2013-04-11	Scinopharm Taiwan Ltd.	Process for making an intermediate of cabazitaxel
CN104250235B (zh) *	2014-09-24	2016-10-05	江苏红豆杉药业有限公司	一种紫杉醇的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4942184A (en) *	1988-03-07	1990-07-17	The United States Of America As Represented By The Department Of Health And Human Services	Water soluble, antineoplastic derivatives of taxol

1994
- 1994-01-26 IL IL10844494A patent/IL108444A0/xx unknown
- 1994-01-28 AU AU61327/94A patent/AU685778B2/en not_active Ceased
- 1994-01-28 AT AT94907959T patent/ATE220064T1/de not_active IP Right Cessation
- 1994-01-28 WO PCT/US1994/001223 patent/WO1994017052A1/en not_active Ceased
- 1994-01-28 CA CA002155013A patent/CA2155013C/en not_active Expired - Fee Related
- 1994-01-28 DE DE69430902T patent/DE69430902T2/de not_active Expired - Fee Related
- 1994-01-28 EP EP94907959A patent/EP0681573B1/de not_active Expired - Lifetime
- 1994-01-28 JP JP51740094A patent/JP3452928B2/ja not_active Expired - Fee Related
- 1994-01-28 DK DK94907959T patent/DK0681573T3/da active
- 1994-01-28 ES ES94907959T patent/ES2176237T3/es not_active Expired - Lifetime
- 1994-01-28 PT PT94907959T patent/PT681573E/pt unknown
- 1994-01-29 CN CN94101158A patent/CN1125061C/zh not_active Expired - Fee Related
- 1994-01-31 CA CA002155014A patent/CA2155014C/en not_active Expired - Fee Related
- 1994-01-31 AT AT94909517T patent/ATE217870T1/de not_active IP Right Cessation
- 1994-01-31 AU AU62340/94A patent/AU684268B2/en not_active Ceased
- 1994-01-31 EP EP94909517A patent/EP0681575B1/de not_active Expired - Lifetime
- 1994-01-31 DE DE69430661T patent/DE69430661T2/de not_active Expired - Fee Related
- 1994-01-31 WO PCT/US1994/001099 patent/WO1994017051A1/en not_active Ceased
- 1994-01-31 JP JP51738694A patent/JP3741715B2/ja not_active Expired - Fee Related
- 1994-04-18 TW TW083103421A patent/TW360646B/zh not_active IP Right Cessation
- 1994-05-12 TW TW083104292A patent/TW402598B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0681575B1 (de)	2002-05-22
CN1101346A (zh)	1995-04-12
JP3452928B2 (ja)	2003-10-06
EP0681575A1 (de)	1995-11-15
IL108444A0 (en)	1994-04-12
DE69430661T2 (de)	2002-10-24
EP0681573A4 (de)	1995-12-06
CA2155013A1 (en)	1994-08-04
AU6132794A (en)	1994-08-15
AU685778B2 (en)	1998-01-29
WO1994017052A1 (en)	1994-08-04
JPH08506326A (ja)	1996-07-09
AU6234094A (en)	1994-08-15
WO1994017051A1 (en)	1994-08-04
DE69430902D1 (de)	2002-08-08
EP0681573B1 (de)	2002-07-03
TW360646B (en)	1999-06-11
CN1125061C (zh)	2003-10-22
CA2155014A1 (en)	1994-08-04
DE69430661D1 (de)	2002-06-27
DE69430902T2 (de)	2002-10-24
AU684268B2 (en)	1997-12-11
EP0681573A1 (de)	1995-11-15
CA2155014C (en)	2007-06-26
CA2155013C (en)	2006-04-11
JP3741715B2 (ja)	2006-02-01
PT681573E (pt)	2002-11-29
TW402598B (en)	2000-08-21
ATE217870T1 (de)	2002-06-15
DK0681573T3 (da)	2002-10-28
EP0681575A4 (de)	1995-12-13
ES2176237T3 (es)	2002-12-01
JPH10502327A (ja)	1998-03-03

Legal Events

Date	Code	Title	Description
2002-10-15	UEP	Publication of translation of european patent specification
2008-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
TR199800825T2 (xx)	1998-08-21	Farnesil protein transferini inhibe eden (imidazol-5-il) metil-2-kinolinon t�revleri.
FI914723A0 (fi)	1991-10-07	17b-substituerade 4-aza-5a-androstan -3-jon-derivat och foerfarande foer framstaellning av desamma.
TR200101969T2 (tr)	2001-10-22	Enflamasyon tedavisi için sübstitüe edilmiş benzopiran analogları.
TR199901174T2 (xx)	1999-08-23	Yeni heterosiklilmetil-ikameli pirazol t�revleri.
IL123002A0 (en)	1998-08-16	1-Phenyl-2- phenylacetoxy- ethanone derivatives
CY1108610T1 (el)	2014-04-09	Πεπτιδια της il-2 και παραγωγα αυτων και χρηση αυτων ως θεραπευτικοι παραγοντες
ATE197672T1 (de)	2000-12-15	Arzneimittel gegen nervöse erkrankungen
PT741716E (pt)	2002-12-31	Analogos de delta 12,13-iso-taxol sua utilizacao anti-neoplasica e composicoes farmaceuticas que os contem
DK0815087T3 (da)	2002-03-11	Trisubstituerede phenylderivater
ATE220064T1 (de)	2002-07-15	C2-taxan-derivate sowie diese enthaltende arzneimittel
PT929565E (pt)	2002-10-31	Esteres de nitrato de compostos corticoides e suas aplicacoes farmaceuticas
FI952734A0 (fi)	1995-06-05	2-Amino-6-A-propyyli-amino-4,5,6,7-tetrahydrobentsotiatsolin (Pramipexolin) käyttö lääkeaineena, jolla on antidepressiivinen vaikutus
ES2122637T3 (es)	1998-12-16	Derivados de tiazolidina, su preparacion y los medicamentos que les contienen.
DE69432404D1 (de)	2003-05-08	C7-Taxan-Derivate sowie diese enthaltende Arzneimittel
ATE207076T1 (de)	2001-11-15	Ara-c derivate
FI930171A0 (fi)	1993-01-15	Piperidinfoereningar, framstaellning och anvaendning av dessa
FR2361361A1 (fr)	1978-03-10	Nouveaux derives du cyclopentane et medicaments contenant ces substances
BG98238A (bg)	1995-02-28	Заместени бензотиазолови производни,получаванетоим и приложението им като хербициди
NO20020914D0 (no)	2002-02-25	Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
ES2118248T3 (es)	1998-09-16	Esteres y amidas de 9-cloro-prostaglandina y su empleo para preparar medicamentos.
PT1000067E (pt)	2003-03-31	Tiazolobenzo-heterociclos sua preparacao e medicamentos que os contem
UY24915A1 (es)	2000-12-29	Derivados de benzoxazindiona, aplicación de los mismos y medicamentos que los contienen
FR2707496B1 (fr)	1995-09-22	Compositions pharmaceutiques antiradicalaires et/ou antilipoperoxydantes et/ou hépatotropes.
AR005866A1 (es)	1999-07-21	Composicion farmaceutica antioxidante
JPS52100439A (en)	1977-08-23	Omega-(arysulfonamido)alkylamines