ATE220556T1 - Die verwendung von lactoperoxidase, einem peroxiddonor und thiocyanat zur herstellung eines medikaments zur behandlung einer infektion mit helicobacter pylori - Google Patents

Die verwendung von lactoperoxidase, einem peroxiddonor und thiocyanat zur herstellung eines medikaments zur behandlung einer infektion mit helicobacter pylori

Info

Publication number: ATE220556T1
Authority: AT; Austria
Prior art keywords: pct; lactoperoxidase; thiocyanate; helicobacter pylori; medication
Prior art date: 1996-01-23

Application number

AT97901880T

Other languages

English (en)

Inventor

Carl Olof Claesson

Gustaf Lindewald

Original Assignee

Semper Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-23

Filing date

1997-01-22

Publication date

2002-08-15

1997-01-22 Application filed by Semper Ab filed Critical Semper Ab

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE220556T1 publication Critical patent/ATE220556T1/de

Links

108010023244 Lactoperoxidase Proteins 0.000 title abstract 2
102000045576 Lactoperoxidases Human genes 0.000 title abstract 2
ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 title abstract 2
ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 title abstract 2
229940057428 lactoperoxidase Drugs 0.000 title abstract 2
150000002978 peroxides Chemical class 0.000 title abstract 2
206010019375 Helicobacter infections Diseases 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
230000000844 anti-bacterial effect Effects 0.000 abstract 2
241000590002 Helicobacter pylori Species 0.000 abstract 1
102000010445 Lactoferrin Human genes 0.000 abstract 1
108010063045 Lactoferrin Proteins 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 1
229940078795 lactoferrin Drugs 0.000 abstract 1
235000021242 lactoferrin Nutrition 0.000 abstract 1
230000000069 prophylactic effect Effects 0.000 abstract 1
210000002784 stomach Anatomy 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
- C12Y101/03004—Glucose oxidase (1.1.3.4)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01007—Peroxidase (1.11.1.7), i.e. horseradish-peroxidase

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Dairy Products (AREA)
Confectionery (AREA)
Medicinal Preparation (AREA)

AT97901880T 1996-01-23 1997-01-22 Die verwendung von lactoperoxidase, einem peroxiddonor und thiocyanat zur herstellung eines medikaments zur behandlung einer infektion mit helicobacter pylori ATE220556T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9600233A SE506529C2 (sv)	1996-01-23	1996-01-23	Användning av ett laktoperoxidassystem för framställning av ett läkemedel mot Helicobacter pylori
PCT/SE1997/000098 WO1997026908A1 (en)	1996-01-23	1997-01-22	Use of lactoperoxidase, a peroxide donor and thiocyanate for the manufacture of a medicament for treating helicobacter pylori infection

Publications (1)

Publication Number	Publication Date
ATE220556T1 true ATE220556T1 (de)	2002-08-15

Family

ID=20401114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97901880T ATE220556T1 (de)	1996-01-23	1997-01-22	Die verwendung von lactoperoxidase, einem peroxiddonor und thiocyanat zur herstellung eines medikaments zur behandlung einer infektion mit helicobacter pylori

Country Status (9)

Country	Link
US (1)	US6149908A (de)
EP (1)	EP1007086B1 (de)
JP (1)	JP2000509367A (de)
AT (1)	ATE220556T1 (de)
AU (1)	AU731221B2 (de)
CA (1)	CA2243708C (de)
DE (1)	DE69714083T2 (de)
SE (1)	SE506529C2 (de)
WO (1)	WO1997026908A1 (de)

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US20110229438A1 (en)	2008-10-09	2011-09-22	Anadys Pharmaceuticals, Inc.	Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
JP2009215301A (ja) *	2009-04-27	2009-09-24	Morinaga Milk Ind Co Ltd	プロテアーゼ阻害剤
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JP5306537B2 (ja) *	2010-02-24	2013-10-02	森永乳業株式会社	昆布抽出物を有効成分とする抗菌補助剤、抗菌組成物、及び飲食品
US10640464B2 (en)	2011-01-03	2020-05-05	The William M. Yarbrough Foundation	Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases
US11279674B2 (en)	2011-01-03	2022-03-22	The William M. Yarbrough Foundation	Isothiocyanate functional surfactant and associated method of use
US8933119B2 (en)	2011-01-03	2015-01-13	The William M. Yarbrough Foundation	Method for treating phytophotodermatitis
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US10441561B2 (en)	2012-07-26	2019-10-15	The William M. Yanbrough Foundation	Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer
US10434082B2 (en)	2012-07-26	2019-10-08	The William M. Yarbrough Foundation	Isothiocyanate functional compounds augmented with secondary antineoplastic medicaments and associated methods for treating neoplasms
US9949943B2 (en)	2012-07-26	2018-04-24	The William M. Yarbrough Foundation	Method for treating neurodegenerative diseases
WO2014018874A1 (en)	2012-07-26	2014-01-30	The William M. Yarbrough Foundation	Method for treating skin cancer
US10080734B2 (en)	2012-07-26	2018-09-25	The William M. Yarbrough Foundation	Method for treating autism and other neurodevelopmental disorders
US10434081B2 (en)	2012-07-26	2019-10-08	The William M. Yarbrough Foundation	Inhibitors of macrophage migration inhibitory factor
US10335387B2 (en)	2012-07-26	2019-07-02	The William M. Yarbrough Foundation	Method for treating infectious diseases with isothiocyanate functional compounds
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1996
- 1996-01-23 SE SE9600233A patent/SE506529C2/sv not_active IP Right Cessation
1997
- 1997-01-22 US US09/117,029 patent/US6149908A/en not_active Expired - Fee Related
- 1997-01-22 EP EP97901880A patent/EP1007086B1/de not_active Expired - Lifetime
- 1997-01-22 WO PCT/SE1997/000098 patent/WO1997026908A1/en not_active Ceased
- 1997-01-22 AU AU15627/97A patent/AU731221B2/en not_active Ceased
- 1997-01-22 CA CA002243708A patent/CA2243708C/en not_active Expired - Fee Related
- 1997-01-22 AT AT97901880T patent/ATE220556T1/de not_active IP Right Cessation
- 1997-01-22 DE DE69714083T patent/DE69714083T2/de not_active Expired - Fee Related
- 1997-01-22 JP JP9526782A patent/JP2000509367A/ja active Pending

Also Published As

Publication number	Publication date
EP1007086B1 (de)	2002-07-17
WO1997026908A1 (en)	1997-07-31
CA2243708A1 (en)	1997-07-31
SE506529C2 (sv)	1997-12-22
SE9600233L (sv)	1997-07-24
DE69714083D1 (de)	2002-08-22
JP2000509367A (ja)	2000-07-25
CA2243708C (en)	2007-04-24
US6149908A (en)	2000-11-21
SE9600233D0 (sv)	1996-01-23
AU1562797A (en)	1997-08-20
DE69714083T2 (de)	2003-03-27
AU731221B2 (en)	2001-03-29
EP1007086A1 (de)	2000-06-14

Legal Events

Date	Code	Title	Description
2003-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE220556T1 (de)	2002-08-15	Die verwendung von lactoperoxidase, einem peroxiddonor und thiocyanat zur herstellung eines medikaments zur behandlung einer infektion mit helicobacter pylori
ATE256475T1 (de)	2004-01-15	Verwendung von follistatin zur herstellung eines arzneimittels zur behandlung von muskuläre krankheiten
DE69527052D1 (de)	2002-07-18	Verwendung von Wasser mit verringertem Deuterium-Gehalt zur Herstellung von hygienischen und kosmetischen Präparaten
DE59610355D1 (de)	2003-05-22	Medizinisches implantat
ATE174797T1 (de)	1999-01-15	Formulierung und verwendung von mikroorganismen zur behandlung von vieh
MY113059A (en)	2001-11-30	Controlled-release dosage forms of azithromycin
DE69533593D1 (de)	2004-11-04	Zubereitungen zur behandlung von gastrointestinalen störungen, welche arabinogalactan und polyphenole von larix enthalten.
DE69526937D1 (de)	2002-07-11	Verwendung von methanbisphosphonsäurederivaten zur behandlung von aufgelockerten prothesen
ATE173578T1 (de)	1998-12-15	Implantierbare formkörper zur verabreichung von wirkstoffen an pflanzen
ATE77751T1 (de)	1992-07-15	Mittel zur behandlung von knochenkrankheiten.
DE59605959D1 (de)	2000-11-09	Verwendung von Immunglobulin-Präparationen zur Herstellung eines Medikaments zur oralen Verabreichung zur Behandlung und Prophylaxe chronischer Schmerzzustände
ATE131064T1 (de)	1995-12-15	Behandlung zur ermässigung von ödem und muskelschäden.
ATE106736T1 (de)	1994-06-15	Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes.
DE59107536D1 (de)	1996-04-18	Arzneimittel zur behandlung von hyperlipidämie und/oder atherosklerose
ATE190839T1 (de)	2000-04-15	Verwendung von prodelphidinen zur behandlung von arthrose
DE69516110D1 (de)	2000-05-11	Verwendung von riluzol zur behandlung mitochondrialer erkrankungen
DE50100833D1 (de)	2003-11-27	Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure und / oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
ATE197545T1 (de)	2000-12-15	Verwendung von aspirin zur herstellung eines arzneimittels zur verbesserung fer blutperfusion des uterus
ATE207353T1 (de)	2001-11-15	Verwendung von benzydamin zur behandlung von krankheitszuständen, die durch tnf verursacht werden
DE69124382D1 (de)	1997-03-06	Authentischen igf-1 und hypokalorische menge von nährstoffen enthaltendes produkt und dessen verwendung zur behandlung kataboler zustände
ATE291353T1 (de)	2005-04-15	Verwendung von milchsaürebakterien bei der herstellung von fermentierten milchprodukten zur behandlung von verringerten immunitätsebenen
DE3476968D1 (en)	1989-04-13	Vaccine and process for its preparation
FR2782641B1 (fr)	2002-05-10	Medicament homeopathique comprenant un ou plusieurs composants de la nacre
Grad	1972	Science investigates laying on of hands
RU4473U1 (ru)	1997-07-16	Приспособление для санации женщин с массивной микробной обсемененностью грудного молока