ATE221086T1 - Photovernetztes hyaluronsäuregel und verfahren zu dessen herstellung - Google Patents

Photovernetztes hyaluronsäuregel und verfahren zu dessen herstellung

Info

Publication number
ATE221086T1
ATE221086T1 AT96938473T AT96938473T ATE221086T1 AT E221086 T1 ATE221086 T1 AT E221086T1 AT 96938473 T AT96938473 T AT 96938473T AT 96938473 T AT96938473 T AT 96938473T AT E221086 T1 ATE221086 T1 AT E221086T1
Authority
AT
Austria
Prior art keywords
hyaluronic acid
pct
date
acid gel
photo
Prior art date
Application number
AT96938473T
Other languages
English (en)
Inventor
Michinori Waki
Kenji Miyamoto
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of ATE221086T1 publication Critical patent/ATE221086T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
AT96938473T 1995-11-15 1996-11-14 Photovernetztes hyaluronsäuregel und verfahren zu dessen herstellung ATE221086T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31982595 1995-11-15
PCT/JP1996/003349 WO1997018244A1 (en) 1995-11-15 1996-11-14 Photocured cross-linked-hyaluronic acid gel and method of preparation thereof

Publications (1)

Publication Number Publication Date
ATE221086T1 true ATE221086T1 (de) 2002-08-15

Family

ID=18114635

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938473T ATE221086T1 (de) 1995-11-15 1996-11-14 Photovernetztes hyaluronsäuregel und verfahren zu dessen herstellung

Country Status (14)

Country Link
US (1) US6031017A (de)
EP (1) EP0861270B1 (de)
JP (1) JP3439481B2 (de)
KR (1) KR100509882B1 (de)
CN (1) CN1098863C (de)
AT (1) ATE221086T1 (de)
AU (1) AU722250B2 (de)
CA (1) CA2237192C (de)
DE (1) DE69622575T2 (de)
ES (1) ES2179215T3 (de)
HU (1) HU224697B1 (de)
NO (1) NO982212L (de)
RU (1) RU2197501C2 (de)
WO (1) WO1997018244A1 (de)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
DE60117502T2 (de) * 2000-12-19 2006-08-24 Seikagaku Corp. Photohärtbare Derivate von Hyaluronsäure, Verfahren zu deren Herstellung, vernetztes und photogehärtetes Derivat der Hyaluronsäure und diese enthaltendes medizinisches Material
JP4172176B2 (ja) * 2000-12-19 2008-10-29 生化学工業株式会社 光反応性ヒアルロン酸およびその製造方法ならびに光架橋ヒアルロン酸および医用材料
FR2819722B1 (fr) * 2001-01-19 2006-11-24 Corneal Ind Utilisation de l'acide hyaluronique ou d'au moins l'un de ses sels dans le cadre d'un traitemnet chirurgical de la presbytie
JP4135502B2 (ja) 2001-01-31 2008-08-20 生化学工業株式会社 架橋多糖スポンジ
US6673919B2 (en) 2001-03-30 2004-01-06 Chisso Cororation Chemically modified hyaluronic acid or salts thereof, and a process for producing thereof
EP1249247B1 (de) 2001-03-30 2007-02-28 Chisso Corporation Pharmazeutische Zusammensetzung zur Behandlung gynäkologischer Erkrankungen
JP2003052819A (ja) * 2001-08-10 2003-02-25 Seikagaku Kogyo Co Ltd 薬剤充填注射器包装物およびその滅菌または殺菌方法
ITPD20020064A1 (it) * 2002-03-12 2003-09-12 Fidia Advanced Biopolymers Srl Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem
KR20040009891A (ko) * 2002-07-26 2004-01-31 주식회사 엘지생명과학 히알루론산의 유도체 겔 및 그 제조방법
EP1534764B1 (de) * 2002-08-09 2014-07-16 Carnegie Mellon University Polymere, superweichelastomere und verfahren zur herstellung derselben
US8137688B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US6982298B2 (en) 2003-01-10 2006-01-03 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
DE602004032525D1 (de) 2003-03-11 2011-06-16 Seikagaku Kogyo Co Ltd Rstellungsverfahren dafür
JP2004323454A (ja) * 2003-04-25 2004-11-18 Chisso Corp 薬剤
DE602004027055D1 (de) * 2003-09-12 2010-06-17 Seikagaku Kogyo Co Ltd Polysaccharid-pseudoschwamm
US7893174B2 (en) * 2004-03-05 2011-02-22 Carnegie Mellon University Atom transfer radical polymerization process
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
CA2578678C (en) * 2004-09-15 2012-07-31 Seikagaku Corporation Photoreactive polysaccharide, photocrosslinked polysaccharide products, the method of making them and medical materials therefrom
US20060069063A1 (en) * 2004-09-27 2006-03-30 Yng-Jiin Wang Crosslinked polygalacturonic acid used for postsurgical tissue adhesion prevention
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
EP2664334B1 (de) * 2004-12-30 2015-03-04 Genzyme Corporation Therapien zur intraartikulären Viskosupplementation
JP2008546710A (ja) * 2005-06-15 2008-12-25 サーモディクス，インコーポレイティド 光活性化開始剤を含むマクロマー組成物
AU2006266741B2 (en) * 2005-07-06 2011-09-01 Seikagaku Corporation Drug-introduced photo-crosslinked hyaluronic acid derived gel
WO2007026362A2 (en) * 2005-09-02 2007-03-08 Colbar Lifescience Ltd. Cross-linked polysaccharide and protein matrices and methods for their preparation
KR101411067B1 (ko) 2005-10-12 2014-06-27 세이가가쿠 고교 가부시키가이샤 점막에 적용하는 작용제 및 그것의 제조 방법
JP5043364B2 (ja) * 2006-05-01 2012-10-10 生化学工業株式会社 多糖誘導体の製造方法
CN100389145C (zh) * 2006-09-29 2008-05-21 北京大学 含天然高分子的水凝胶及其辐射制备方法
JP5291621B2 (ja) 2006-12-06 2013-09-18 生化学工業株式会社 関節疾患に対する持続的治療効果を有する薬剤
WO2009029049A1 (en) * 2007-08-30 2009-03-05 National University Of Singapore A bone and/or dental cement composition and uses thereof
EP2249891B1 (de) 2008-02-13 2016-05-25 The Cleveland Clinic Foundation Molekulare verstärkung von extrazellulärer matrix und anwendungsverfahren
WO2009117737A2 (en) * 2008-03-21 2009-09-24 Biomimedica, Inc Methods, devices and compositions for adhering hydrated polymer implants to bone
US8410180B2 (en) 2008-04-30 2013-04-02 The Cleveland Clinic Foundation Methods to treat urinary incontinence
WO2010005992A1 (en) * 2008-07-07 2010-01-14 Biomimedica, Inc. Hydrophilic interpenetrating polymer networks derived from hydrophobic polymers
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
EP2323670A4 (de) 2008-08-05 2013-12-25 Biomimedica Inc Polyurethan-gepfropfte hydrogele
US20110229565A1 (en) 2008-09-17 2011-09-22 Karp Jeffrey M Drug Delivery Composition Comprising a Self-Assembled Gelator
ITRM20080636A1 (it) * 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
US8962764B2 (en) 2009-03-27 2015-02-24 Carnegie Mellon University Preparation of functional star macromolecules
WO2010138074A1 (en) * 2009-05-29 2010-12-02 Hilborn Joens Hyaluronic acid based delivery systems
JO3008B1 (ar) * 2009-08-13 2016-09-05 Seikagaku Kogyo Co Ltd تركيب صيدلي لتخفيف الألم
CN101716331B (zh) * 2009-12-16 2012-03-07 中山大学 利用支链淀粉-对硝基肉桂酸接枝物原位包埋蛋白类生物大分子的方法
EP2512354A4 (de) * 2009-12-18 2015-09-09 Biomimedica Inc Verfahren, vorrichtung und system zum schaben und formen eines gelenks
JP2013530785A (ja) * 2010-07-12 2013-08-01 シン・プーン・ファーマシューティカル・カンパニー・リミテッド 組織増大用充填組成物
US20130217829A1 (en) 2010-08-27 2013-08-22 David Myung "hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same"
EP2618821A4 (de) 2010-09-24 2014-08-13 Brigham & Womens Hospital Nanostrukturierte gele zur kontrollierten freisetzung verkapselter mittel
US9644042B2 (en) 2010-12-17 2017-05-09 Carnegie Mellon University Electrochemically mediated atom transfer radical polymerization
ITTO20110428A1 (it) * 2011-05-13 2012-11-14 Rottapharm Spa Esteri dell'acido ialuronico, loro preparazione ed uso in dermatologia
CN102225220A (zh) * 2011-06-14 2011-10-26 天津晶明新技术开发有限公司 眼科手术粘弹剂
US20140275420A1 (en) 2011-08-22 2014-09-18 Carnegie Mellon University Atom transfer radical polymerization under biologically compatible conditions
WO2013052105A2 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
AU2012340699A1 (en) 2011-11-21 2014-06-19 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
US9533297B2 (en) 2012-02-23 2017-01-03 Carnegie Mellon University Ligands designed to provide highly active catalyst complexes
CZ304267B6 (cs) * 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Fotoreaktivní derivát kyseliny hyaluronové, způsob jeho přípravy, 3D síťovaný derivát kyseliny hyaluronové, způsob jeho přípravy a použití
RU2513838C1 (ru) * 2013-02-21 2014-04-20 Общество с ограниченной ответственностью "ДЖИ-Групп" Гистоэквивалент-биопластический материал
KR101869988B1 (ko) * 2013-03-27 2018-06-21 주식회사 엘지화학 점탄성 히알루론산 가교물 제조용 조성물, 및 이를 이용하여 얻은 히알루론산 가교물
JPWO2015053282A1 (ja) * 2013-10-08 2017-03-09 キユーピー株式会社 カルボキシメチル基含有修飾ヒアルロン酸および／またはその塩の架橋物およびその製造方法
EP3085768A4 (de) 2013-12-18 2017-08-09 Japan Science And Technology Agency Struktur für tierzelle, verfahren zur trennung von tierzelle und verfahren zur anpassung der elastizität der oberfläche einer struktur für tierzelle
EP3167914B1 (de) * 2014-07-11 2021-09-29 Menicon Co., Ltd. Material zur sicherstellung der sichtbarkeit und vorrichtung zum entladen des materials zur sicherstellung der sichtbarkeit
US9982070B2 (en) 2015-01-12 2018-05-29 Carnegie Mellon University Aqueous ATRP in the presence of an activator regenerator
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
ES2864651T3 (es) * 2015-09-30 2021-10-14 Univ Jichi Medical Composición viscoelástica
KR20170090965A (ko) * 2016-01-29 2017-08-08 한미약품 주식회사 복합 히알루론산 가교물 및 그 제조방법
US10568840B2 (en) 2016-05-06 2020-02-25 The Brigham And Women's Hospital, Inc. Self assembled gels for controlled delivery of encapsulated agents to cartilage
JPWO2018079812A1 (ja) 2016-10-31 2019-09-19 キユーピー株式会社 ゲル組成物及びその製造方法
WO2018132582A1 (en) 2017-01-12 2018-07-19 Carnegie Mellon University Surfactant assisted formation of a catalyst complex for emulsion atom transfer radical polymerization processes
US11020410B2 (en) 2017-02-03 2021-06-01 The Brigham And Women's Hospital, Inc. Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof
CN106832439A (zh) * 2017-03-26 2017-06-13 广州市芯检康生物科技有限公司 一种用于全血成分保护的新型气凝胶多功能即用型复合材料及其制备方法
JP7211974B2 (ja) * 2017-05-08 2023-01-24 アリヴィオ セラピューティクス， インコーポレイテッド 増大した薬剤負荷および接着のためのナノ構造化ゲルの製剤
CN107469140B (zh) * 2017-08-14 2021-01-05 高鼎精细化工(昆山)有限公司 一种具抗菌功能的光动力学抗菌敷料、制备方法及应用
US12251397B2 (en) * 2018-02-06 2025-03-18 Regen Lab Sa Cross-linked hyaluronic acids and combinations with PRP/BMC
CA3092253C (en) 2018-02-28 2024-10-08 Mochida Pharmaceutical Co., Ltd. NEW PHOTOCROSSABLE ALGINIC ACID DERIVATIVE
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
CN108837299B (zh) * 2018-07-18 2020-08-07 武汉大学 一种智能调节血糖的微针贴片及其制备方法
EP3863602A1 (de) 2018-10-11 2021-08-18 Alivio Therapeutics, Inc. Nicht injizierbare hydrogelformulierungen zur intelligenten freisetzung
EP3884839B1 (de) * 2018-11-22 2026-01-28 Jichi Medical University Viskoelastische endoskopsichtfeldschutzzusammensetzung
BR112021010815A2 (pt) 2018-12-21 2021-08-31 Advanced Aesthetic Technologies, Inc. Polissacarídeos reticulados e métodos relacionados
CN110063758B (zh) * 2019-05-27 2024-06-18 博志生物科技(深圳)有限公司 一种紫外线光固化凝胶微创穿刺注射方法及系统
IT201900019724A1 (it) * 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
CN111617313B (zh) * 2020-04-29 2022-09-06 天津医科大学眼科医院 一种眼用线性凝胶在作为临床孔源性视网膜脱离药物方面中的应用
US20240269349A1 (en) 2021-09-09 2024-08-15 Sunbio Inc. Sol-gel conversion over time of 6-arm peg hydrogel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
CA2121129A1 (en) * 1991-10-29 1993-05-13 Patrick Soon-Shiong Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
JP2855307B2 (ja) * 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法

Also Published As

Publication number Publication date
HUP0000390A2 (hu) 2000-05-28
NO982212L (no) 1998-07-14
NO982212D0 (no) 1998-05-14
US6031017A (en) 2000-02-29
KR19990067621A (ko) 1999-08-25
DE69622575T2 (de) 2003-02-13
DE69622575D1 (de) 2002-08-29
KR100509882B1 (ko) 2006-01-27
CA2237192C (en) 2006-06-20
WO1997018244A1 (en) 1997-05-22
JPH11512778A (ja) 1999-11-02
CA2237192A1 (en) 1997-05-22
HK1015799A1 (en) 1999-10-22
HUP0000390A3 (en) 2000-09-28
AU7587296A (en) 1997-06-05
AU722250B2 (en) 2000-07-27
RU2197501C2 (ru) 2003-01-27
EP0861270A1 (de) 1998-09-02
EP0861270B1 (de) 2002-07-24
JP3439481B2 (ja) 2003-08-25
HU224697B1 (en) 2006-01-30
CN1207744A (zh) 1999-02-10
ES2179215T3 (es) 2003-01-16
CN1098863C (zh) 2003-01-15

Similar Documents

Publication Publication Date Title
DE69622575D1 (de) Photovernetztes hyaluronsäuregel und verfahren zu dessen herstellung
NZ300602A (en) Process for preparing mouldings (ie contact lenses) using cross linked polymers with bound photoinitiators in solution
DE59607301D1 (de) Verfahren zur Herstellung von photopolymeren Hochdruckplatten
ATE244790T1 (de) Tissueprodukte aus baumwoll-linter und verfahren zu ihrer herstellung
DE60025328D1 (de) Verfahren zur herstellung von mehrfach vernetzten hyaluronsäurederivaten
ATE249228T1 (de) Verwendung von polyallylamin-polymeren zur herstellung eines medikamentes zur behandlung von hypercholesterolemia
ATE180408T1 (de) Herstellung eines arzneimittels zur behandlung von augenentzündung durch blockierung von zelladhäsionsmolekulen
ATE188041T1 (de) Perfluoroalkylether enthaltendes polysiloxan and dessen herstellung und verwendung
ATE208389T1 (de) Verfahren zur herstellung von enantiomerenreinen tropasäureestern
DE69606495D1 (de) Verfahren zur Herstellung von depolymerisiertem Naturkautschuk
DE59505079D1 (de) Verfahren zur Herstellung von niedermolekularen Celluloseethern
DE60237520D1 (de) Glycoprotein sowie verfahren zu dessen herstellung
ATE238351T1 (de) Wasserlösliche sulfoalkylgruppenhaltige hydrophob modifizierte celluloseether, verfahren zu deren herstellung sowie deren verwendung als schutzkolloide bei polymerisationen
DE69517191D1 (de) Wasserlösliche derivate epipodophyllotoxine, verfahren zu ihrer herstellung, ihre verwendung als medikament und ihre verwendung zur herstellung eines antikrebsmittels
DE69808771D1 (de) Ein verfahren zur herstellung von tetraaza makrocyclen
DE69531496D1 (de) Alginatfasern, verfahren zur herstellung und verwendung
ATE236895T1 (de) Ringannelierte dihydropyrane, verfahren zur herstellung sowie deren verwendung
ATE216235T1 (de) Verwendung von cholinesterase-inhibitoren für die herstellung eines medikaments zur behandlung von xerostomie
ATE205473T1 (de) Neue borneolderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
BR9609654A (pt) Processo para preparar diretamente uma solução de formiator de celulose solução objeto de formiato de celulose ou de celulose regenerada montagem de reforço e artigo
DE69424415D1 (de) Verwendung von efaroxan und dessen derivaten zur herstellung eines arzneimittels zur behandlung parkinsonscher krankheit
DE69610045D1 (de) Verwendung eines Rohpflanzenextraktes zur Herstellung eines Arzneimittels zur Behandlung von HIV-Infektionen
DE50210977D1 (de) Verfahren zur herstellung eines biologischen gewebes unter verwendung einer kollagenunterlage und zugehöriges gewebekonstrukt
ATE188694T1 (de) Verfahren zur herstellung von benzopyranderivaten
DE69504188D1 (de) Verfahren zur herstellung von 5-amino-1,3-dioxanen