ATE221872T1 - Herstellung von tri-iodo-benzol-verbindungen - Google Patents

Herstellung von tri-iodo-benzol-verbindungen

Info

Publication number: ATE221872T1
Authority: AT; Austria
Prior art keywords: agent; added; temperature; range; iodo
Prior art date: 1997-05-23

Application number

AT98922944T

Other languages

English (en)

Inventor

Dick Malthe-Soerenssen

Ole Magne Homestad

Britt Sterud

Original Assignee

Nycomed Imaging As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-23

Filing date

1998-05-22

Publication date

2002-08-15

1998-05-22 Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE221872T1 publication Critical patent/ATE221872T1/de

Links

RIWAPWDHHMWTRA-UHFFFAOYSA-N 1,2,3-triiodobenzene Chemical class IC1=CC=CC(I)=C1I RIWAPWDHHMWTRA-UHFFFAOYSA-N 0.000 title 1
239000003795 chemical substances by application Substances 0.000 abstract 4
XFDUHJPVQKIXHO-UHFFFAOYSA-N 3-aminobenzoic acid Chemical class NC1=CC=CC(C(O)=O)=C1 XFDUHJPVQKIXHO-UHFFFAOYSA-N 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 2
239000012336 iodinating agent Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
239000012736 aqueous medium Substances 0.000 abstract 1
239000012431 aqueous reaction media Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052740 iodine Inorganic materials 0.000 abstract 1
239000011630 iodine Substances 0.000 abstract 1
-1 iodine halide Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Glass Compositions (AREA)
Iron Core Of Rotating Electric Machines (AREA)

AT98922944T 1997-05-23 1998-05-22 Herstellung von tri-iodo-benzol-verbindungen ATE221872T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9710725.4A GB9710725D0 (en)	1997-05-23	1997-05-23	Process
PCT/GB1998/001488 WO1998052908A1 (en)	1997-05-23	1998-05-22	Preparation of tri-iodo benzene compounds

Publications (1)

Publication Number	Publication Date
ATE221872T1 true ATE221872T1 (de)	2002-08-15

Family

ID=10812987

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98922944T ATE221872T1 (de)	1997-05-23	1998-05-22	Herstellung von tri-iodo-benzol-verbindungen

Country Status (17)

Country	Link
US (1)	US6274762B1 (de)
EP (1)	EP0984922B1 (de)
JP (1)	JP4039700B2 (de)
KR (1)	KR100544932B1 (de)
CN (1)	CN1152854C (de)
AT (1)	ATE221872T1 (de)
AU (1)	AU7540498A (de)
BR (1)	BR9809658A (de)
CA (1)	CA2290529A1 (de)
CZ (1)	CZ296389B6 (de)
DE (1)	DE69807073T2 (de)
ES (1)	ES2183366T3 (de)
GB (1)	GB9710725D0 (de)
IL (1)	IL133099A0 (de)
NO (1)	NO327489B1 (de)
PT (1)	PT984922E (de)
WO (1)	WO1998052908A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100355710C (zh) *	2005-12-15	2007-12-19	上海交通大学	芳烃碘代物的制备方法
EP2243767A1 (de) *	2009-04-21	2010-10-27	Bracco Imaging S.p.A	Verfahren zur Iodierung aromatischer Verbindungen
US20110021834A1 (en) *	2009-07-21	2011-01-27	Ge Healthcare As	Continuous process of preparing intermediate for non-ionic x-ray contrast agents
US20110020238A1 (en) *	2009-07-21	2011-01-27	Ge Healthcare As	Stabilizing aqueous solution of iodine chloride by adding sodium chloride
US7863484B1 (en)	2009-07-21	2011-01-04	Ge Healthcare As	Method for reducing aminoisophthalic acid bisamide related impurities in preparation of non-ionic X-ray contrast agents
EP2277846A1 (de)	2009-07-21	2011-01-26	GE Healthcare AS	Erhalt freien Iods bei der Herstellung von wässrigem Iodchlorid durch Zugabe von Iodid
US20110021833A1 (en) *	2009-07-21	2011-01-27	Ge Healthcare As	Crystallization of an intermediate for synthesizing non-ionic x-ray contrast agents
JP5754842B2 (ja) *	2011-03-02	2015-07-29	株式会社東邦アーステック	ｐ−ヨードフェノールの製造方法
US9382194B2 (en)	2011-10-31	2016-07-05	Imax Diagnostic Imaging Holding Limited	Iodination process for the preparation of 3, 5-disubstituted-2, 4, 6-triiodo aromatic amines compounds
CN103086915A (zh) *	2011-10-31	2013-05-08	上海海神化学生物科技有限公司	制备3,5-二取代-2,4,6-三碘代芳香胺类化合物的碘化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3145197A (en) *	1961-06-26	1964-08-18	Mallinckrodt Chemical Works	5-acetamido-nu-alkyl-2, 4, 6-trhodoiso-phthalamic acid compounds
SE348727B (de) *	1969-07-08	1972-09-11	Pharmacia Ab
GB1466852A (en) *	1973-05-18	1977-03-09	Nyegaard & Co As	Iodination process
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
US4125599A (en) *	1976-08-19	1978-11-14	Mallinckrodt, Inc.	X-ray contrast agents
FR2614299B1 (fr) *	1987-04-23	1989-08-18	Guerbet Sa	Composes diamino benzeniques iodes, leur procede de preparation et produits de contraste les contenant.
EP0408654B1 (de) *	1988-04-06	1995-05-24	Mallinckrodt, Inc.	Verfahren zur herstellung von 2,4,6-triiodo-5-amino-n-alkyl-isophthalsäure
US5013865A (en) *	1988-04-06	1991-05-07	Mallinckrodt, Inc.	Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds

1997
- 1997-05-23 GB GBGB9710725.4A patent/GB9710725D0/en active Pending
1998
- 1998-05-22 WO PCT/GB1998/001488 patent/WO1998052908A1/en not_active Ceased
- 1998-05-22 BR BR9809658-3A patent/BR9809658A/pt not_active IP Right Cessation
- 1998-05-22 EP EP98922944A patent/EP0984922B1/de not_active Expired - Lifetime
- 1998-05-22 CZ CZ0417299A patent/CZ296389B6/cs not_active IP Right Cessation
- 1998-05-22 IL IL13309998A patent/IL133099A0/xx unknown
- 1998-05-22 CN CNB988053209A patent/CN1152854C/zh not_active Expired - Lifetime
- 1998-05-22 AT AT98922944T patent/ATE221872T1/de not_active IP Right Cessation
- 1998-05-22 ES ES98922944T patent/ES2183366T3/es not_active Expired - Lifetime
- 1998-05-22 KR KR1019997010788A patent/KR100544932B1/ko not_active Expired - Lifetime
- 1998-05-22 CA CA002290529A patent/CA2290529A1/en not_active Abandoned
- 1998-05-22 JP JP55013798A patent/JP4039700B2/ja not_active Expired - Lifetime
- 1998-05-22 DE DE69807073T patent/DE69807073T2/de not_active Expired - Lifetime
- 1998-05-22 PT PT98922944T patent/PT984922E/pt unknown
- 1998-05-22 AU AU75404/98A patent/AU7540498A/en not_active Abandoned
1999
- 1999-11-12 US US09/432,632 patent/US6274762B1/en not_active Expired - Lifetime
- 1999-11-19 NO NO19995675A patent/NO327489B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9809658A (pt)	2000-07-11
EP0984922A1 (de)	2000-03-15
IL133099A0 (en)	2001-03-19
GB9710725D0 (en)	1997-07-16
US6274762B1 (en)	2001-08-14
EP0984922B1 (de)	2002-08-07
DE69807073D1 (de)	2002-09-12
CN1152854C (zh)	2004-06-09
CZ417299A3 (cs)	2000-05-17
WO1998052908A1 (en)	1998-11-26
KR100544932B1 (ko)	2006-01-24
AU7540498A (en)	1998-12-11
DE69807073T2 (de)	2003-10-09
ES2183366T3 (es)	2003-03-16
CA2290529A1 (en)	1998-11-26
PT984922E (pt)	2002-12-31
KR20010012824A (ko)	2001-02-26
JP2001526677A (ja)	2001-12-18
NO327489B1 (no)	2009-07-13
CZ296389B6 (cs)	2006-03-15
JP4039700B2 (ja)	2008-01-30
NO995675D0 (no)	1999-11-19
CN1257476A (zh)	2000-06-21
NO995675L (no)	1999-11-19

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Legal Events

Date	Code	Title	Description
2003-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties