ATE221919T1 - In flüssiger form stabiler thiolaktivator - Google Patents

In flüssiger form stabiler thiolaktivator

Info

Publication number: ATE221919T1
Authority: AT; Austria
Prior art keywords: solution; liquid form; thiol activator; activator; thiol
Prior art date: 1994-05-06

Application number

AT95918415T

Other languages

English (en)

Inventor

Carrie J Lu

Frederick S Yein

Original Assignee

Beckman Coulter Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-06

Filing date

1995-05-05

Publication date

2002-08-15

1995-05-05 Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc

2002-08-15 Application granted granted Critical

2002-08-15 Publication of ATE221919T1 publication Critical patent/ATE221919T1/de

Links

150000003573 thiols Chemical class 0.000 title abstract 4
239000012190 activator Substances 0.000 title abstract 3
239000007788 liquid Substances 0.000 title 1
239000000243 solution Substances 0.000 abstract 3
102000004420 Creatine Kinase Human genes 0.000 abstract 1
108010042126 Creatine kinase Proteins 0.000 abstract 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 abstract 1
229930195725 Mannitol Natural products 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
239000000594 mannitol Substances 0.000 abstract 1
235000010355 mannitol Nutrition 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT95918415T 1994-05-06 1995-05-05 In flüssiger form stabiler thiolaktivator ATE221919T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23926094A	1994-04-20	1994-04-20
PCT/US1995/005702 WO1995030769A1 (en)	1994-05-06	1995-05-05	Liquid stable thiol activator

Publications (1)

Publication Number	Publication Date
ATE221919T1 true ATE221919T1 (de)	2002-08-15

Family

ID=22901361

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95918415T ATE221919T1 (de)	1994-05-06	1995-05-05	In flüssiger form stabiler thiolaktivator

Country Status (9)

Country	Link
US (1)	US5700653A (de)
EP (1)	EP0707658B1 (de)
JP (1)	JP3619865B2 (de)
AT (1)	ATE221919T1 (de)
AU (1)	AU692547B2 (de)
CA (1)	CA2165808A1 (de)
DE (1)	DE69527686T2 (de)
ES (1)	ES2180632T3 (de)
WO (1)	WO1995030769A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19755079A1 (de)	1997-12-11	1999-06-17	Roche Diagnostics Gmbh	Stabilisiertes Reagenz und Verfahren zur Bestimmung von Creatin-Kinase
US5908864A (en) *	1998-05-28	1999-06-01	Dymatize Enterprises	Creatine gel
DE59913906D1 (de)	1998-12-22	2006-11-23	Olympus Diagnostica Gmbh	Flüssigreagenz für den Nachweis von Kreatinkinase
AU2404500A (en) *	1999-01-08	2000-07-24	Medical Analysis Systems, Inc.	Compositions and methods for stabilizing thiol-containing biomolecules
US20060020035A1 (en) *	2004-03-11	2006-01-26	Oregon Health & Science University	Bone marrow protection with N-acetyl-L-cysteine
US8148356B2 (en)	2005-08-24	2012-04-03	Cumberland Pharmaceuticals, Inc.	Acetylcysteine composition and uses therefor
AU2011202871B2 (en) *	2005-08-24	2014-06-12	Cumberland Pharmaceuticals Inc.	Acetylcysteine composition and uses therefor
JP5468299B2 (ja) *	2009-05-15	2014-04-09	旭化成ファーマ株式会社	Ｉｍｐｄｈ含有組成物及びｉｍｐｄｈの安定化方法
CN105168135A (zh) *	2010-03-12	2015-12-23	博格有限责任公司	辅酶Q10(CoQ10)的静脉内制剂及其使用方法
US10973763B2 (en)	2011-06-17	2021-04-13	Berg Llc	Inhalable pharmaceutical compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2648759C3 (de) *	1976-10-27	1979-05-31	Boehringer Mannheim Gmbh, 6800 Mannheim	Stabilisierungsmittel für Enzyme
US4339533A (en) *	1980-07-30	1982-07-13	Technicon Instruments Corporation	Stabilization of creatine kinase (CK) and its application as a reference standard
US4883762A (en) *	1983-06-06	1989-11-28	Ciba Corning Diagnostics Corp.	Stabilized isoenzyme control products
JPS6188899A (ja) *	1984-10-05	1986-05-07	Unitika Ltd	クレアチンキナ−ゼ定量用試薬
JPS62104598A (ja) *	1985-11-01	1987-05-15	Yatoron:Kk	クレアチンキナ−ゼ測定用試薬
FR2610626B1 (fr) *	1987-02-09	1989-05-19	Oreal	Nouveau systeme anti-oxydant a base d'un ester d'ascorbyle stabilise, contenant en association au moins un agent complexant et au moins un thiol, et compositions contenant un tel systeme anti-oxydant
JPS63283600A (ja) *	1987-05-18	1988-11-21	Fuji Photo Film Co Ltd	クレアチンキナ−ゼ活性測定用分析要素
JPH0690202B2 (ja) *	1988-04-06	1994-11-14	ユニチカ株式会社	クレアチンキナーゼ活性測定用試薬およびそれを用いる測定方法
CA2028593C (en) *	1989-10-31	2007-08-21	Douglas R. Brandt	Stabilized enzyme compositions
IT1242642B (it) *	1990-04-17	1994-05-16	Alfa Wassermann Spa	Formulazioni iniettabili contenenti naproxen sale sodico.
US5192657A (en) *	1990-12-18	1993-03-09	Ortho Diagnostic Systems, Inc.	Stabilized proteolytic solution and reagent kit
JPH05111396A (ja) *	1991-07-17	1993-05-07	Oriental Yeast Co Ltd	クレアチンキナ−ゼの活性測定方法およびそれに用いる試薬
US5298406A (en) *	1992-09-14	1994-03-29	E. I. Du Pont De Nemours And Company	Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes

1995
- 1995-05-05 AU AU24367/95A patent/AU692547B2/en not_active Ceased
- 1995-05-05 ES ES95918415T patent/ES2180632T3/es not_active Expired - Lifetime
- 1995-05-05 DE DE69527686T patent/DE69527686T2/de not_active Expired - Fee Related
- 1995-05-05 JP JP52915095A patent/JP3619865B2/ja not_active Expired - Fee Related
- 1995-05-05 WO PCT/US1995/005702 patent/WO1995030769A1/en not_active Ceased
- 1995-05-05 CA CA002165808A patent/CA2165808A1/en not_active Abandoned
- 1995-05-05 EP EP95918415A patent/EP0707658B1/de not_active Expired - Lifetime
- 1995-05-05 AT AT95918415T patent/ATE221919T1/de not_active IP Right Cessation
- 1995-10-09 US US08/541,473 patent/US5700653A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0707658A1 (de)	1996-04-24
WO1995030769A1 (en)	1995-11-16
AU2436795A (en)	1995-11-29
CA2165808A1 (en)	1995-11-16
EP0707658B1 (de)	2002-08-07
US5700653A (en)	1997-12-23
AU692547B2 (en)	1998-06-11
DE69527686D1 (de)	2002-09-12
JPH09500027A (ja)	1997-01-07
DE69527686T2 (de)	2003-04-03
JP3619865B2 (ja)	2005-02-16
ES2180632T3 (es)	2003-02-16

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Legal Events

Date	Code	Title	Description
2003-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties