ATE223908T1 - Benzenderivat und pharmezeutische zusammensetzung - Google Patents
Benzenderivat und pharmezeutische zusammensetzungInfo
- Publication number
- ATE223908T1 ATE223908T1 AT95108406T AT95108406T ATE223908T1 AT E223908 T1 ATE223908 T1 AT E223908T1 AT 95108406 T AT95108406 T AT 95108406T AT 95108406 T AT95108406 T AT 95108406T AT E223908 T1 ATE223908 T1 AT E223908T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- nhr
- alkyl
- benzene derivative
- azole
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical class C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 4
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 150000001555 benzenes Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14227694 | 1994-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE223908T1 true ATE223908T1 (de) | 2002-09-15 |
Family
ID=15311600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95108406T ATE223908T1 (de) | 1994-06-01 | 1995-06-01 | Benzenderivat und pharmezeutische zusammensetzung |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US5696118A (de) |
| EP (1) | EP0685470B1 (de) |
| AT (1) | ATE223908T1 (de) |
| AU (1) | AU675035B2 (de) |
| CA (1) | CA2150610C (de) |
| DE (1) | DE69528110T2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2887179B2 (ja) * | 1996-05-17 | 1999-04-26 | 呉羽化学工業株式会社 | 芳香族化合物 |
| JPH10203981A (ja) * | 1997-01-21 | 1998-08-04 | Kureha Chem Ind Co Ltd | 心疾患改善剤 |
| CN101011390A (zh) * | 1999-01-26 | 2007-08-08 | 诺瓦提斯公司 | 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用 |
| US7063260B2 (en) * | 2003-03-04 | 2006-06-20 | Lightsmyth Technologies Inc | Spectrally-encoded labeling and reading |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE874443C (de) * | 1941-05-23 | 1953-04-23 | Theodor H Temmler | Verfahren zur Herstellung von Monoaminobenzolsulfoderivaten von Diaminen |
| CH302372A (de) * | 1951-08-21 | 1954-10-15 | Durand & Huguenin Ag | Verfahren zur Herstellung einer neuen Acetoacetylaminoverbindung. |
| FR1479207A (fr) * | 1962-04-20 | 1967-05-05 | Procédé de préparation des morpholides d'acides cycliques mono- et polyhydroxylés et des sels alcalins hydrosolubles de ces morpholides, et produits en résultant | |
| US3829487A (en) * | 1971-04-19 | 1974-08-13 | Merck & Co Inc | N-substituted-3,5-(trifluoromethyl or bromo)benzenesulfonamides |
| CH632628B (de) * | 1976-07-26 | Ciba Geigy Ag | Verfahren zur herstellung von benzofuranyl-benzimidazolen und deren verwendung als optische aufheller. | |
| DD205901A1 (de) * | 1982-06-22 | 1984-01-11 | Gerhard Kempter | Verfahren zur herstellung von 3-amino-benzen-sulfonyl-n-cycloimiden |
| FR2553414B1 (fr) * | 1983-10-18 | 1986-08-14 | Choay Sa | Nouveaux benzenesulfonamides n-cyclises, leur procede de preparation et leur utilisation comme substance active de compositions pharmaceutiques |
| ZA859186B (en) * | 1984-12-18 | 1986-08-27 | Daiichi Seiyaku Co | Aminobenzamide derivatives |
| IL95975A (en) * | 1989-10-24 | 1997-06-10 | Takeda Chemical Industries Ltd | N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them |
| JPH06335579A (ja) * | 1993-05-31 | 1994-12-06 | Juki Corp | ワーク搬送装置 |
-
1995
- 1995-05-31 CA CA002150610A patent/CA2150610C/en not_active Expired - Fee Related
- 1995-06-01 US US08/457,147 patent/US5696118A/en not_active Expired - Fee Related
- 1995-06-01 AU AU20428/95A patent/AU675035B2/en not_active Ceased
- 1995-06-01 AT AT95108406T patent/ATE223908T1/de not_active IP Right Cessation
- 1995-06-01 EP EP95108406A patent/EP0685470B1/de not_active Expired - Lifetime
- 1995-06-01 DE DE69528110T patent/DE69528110T2/de not_active Expired - Fee Related
-
1996
- 1996-08-23 US US08/702,116 patent/US5731310A/en not_active Expired - Fee Related
-
1997
- 1997-04-30 US US08/841,621 patent/US5739131A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69528110D1 (de) | 2002-10-17 |
| US5731310A (en) | 1998-03-24 |
| EP0685470A3 (de) | 1996-02-07 |
| AU2042895A (en) | 1996-01-04 |
| CA2150610A1 (en) | 1995-12-02 |
| CA2150610C (en) | 1999-08-17 |
| US5696118A (en) | 1997-12-09 |
| AU675035B2 (en) | 1997-01-16 |
| EP0685470A2 (de) | 1995-12-06 |
| US5739131A (en) | 1998-04-14 |
| DE69528110T2 (de) | 2003-01-16 |
| EP0685470B1 (de) | 2002-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |