ATE228006T1 - Verwendung von vip zur erstellung eines medikamentes zur behandlung des endotoxischen schocks in säugetieren - Google Patents
Verwendung von vip zur erstellung eines medikamentes zur behandlung des endotoxischen schocks in säugetierenInfo
- Publication number
- ATE228006T1 ATE228006T1 AT99913324T AT99913324T ATE228006T1 AT E228006 T1 ATE228006 T1 AT E228006T1 AT 99913324 T AT99913324 T AT 99913324T AT 99913324 T AT99913324 T AT 99913324T AT E228006 T1 ATE228006 T1 AT E228006T1
- Authority
- AT
- Austria
- Prior art keywords
- vip
- mammals
- endotoxic shock
- medication
- create
- Prior art date
Links
- 206010014824 Endotoxic shock Diseases 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title abstract 2
- 206010040070 Septic Shock Diseases 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 102000055135 Vasoactive Intestinal Peptide Human genes 0.000 abstract 2
- 108010003205 Vasoactive Intestinal Peptide Proteins 0.000 abstract 2
- VBUWHHLIZKOSMS-RIWXPGAOSA-N invicorp Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=C(O)C=C1 VBUWHHLIZKOSMS-RIWXPGAOSA-N 0.000 abstract 2
- 239000012190 activator Substances 0.000 abstract 1
- 108060000200 adenylate cyclase Proteins 0.000 abstract 1
- 102000030621 adenylate cyclase Human genes 0.000 abstract 1
- 230000017074 necrotic cell death Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001173 tumoral effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Manufacture Of Tobacco Products (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009800814A ES2138561B1 (es) | 1998-04-17 | 1998-04-17 | Uso de los peptidos vip y pacap en el tratamiento del shock endotoxico en mamiferos. |
| PCT/ES1999/000101 WO1999053944A1 (es) | 1998-04-17 | 1999-04-16 | Metodo para el tratamiento del 'shock' endotoxico en mamiferos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228006T1 true ATE228006T1 (de) | 2002-12-15 |
Family
ID=8303495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99913324T ATE228006T1 (de) | 1998-04-17 | 1999-04-16 | Verwendung von vip zur erstellung eines medikamentes zur behandlung des endotoxischen schocks in säugetieren |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6429188B1 (de) |
| EP (1) | EP1002542B1 (de) |
| JP (1) | JP2002507224A (de) |
| AT (1) | ATE228006T1 (de) |
| AU (1) | AU3148699A (de) |
| CA (1) | CA2294980A1 (de) |
| DE (1) | DE69904010T2 (de) |
| ES (1) | ES2138561B1 (de) |
| PT (1) | PT1002542E (de) |
| WO (1) | WO1999053944A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60002143T2 (de) * | 1999-06-04 | 2004-03-18 | Universidad Complutense De Madrid | Behandlung autoimmunerkrankungen in säugern |
| WO2003096024A1 (en) * | 2002-05-08 | 2003-11-20 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with vasoactive intestinal peptide receptor 2 (vpac2) |
| US7547450B2 (en) * | 2002-10-24 | 2009-06-16 | Nestec Ltd. | Senior feline food |
| AU2003284678B2 (en) * | 2003-02-24 | 2006-02-23 | Morinaga Milk Industry Co., Ltd. | Interleukin 6 production inhibitor |
| US8841255B2 (en) | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
| CN101384272B (zh) | 2005-12-20 | 2013-05-01 | 杜克大学 | 用于递送具有增强的药理性质的活性剂的方法和组合物 |
| US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
| US8178495B2 (en) | 2008-06-27 | 2012-05-15 | Duke University | Therapeutic agents comprising a GLP-1 receptor agonist and elastin-like peptide |
| PL3311828T3 (pl) * | 2009-08-14 | 2021-11-22 | Phasebio Pharmaceuticals, Inc. | Zmodyfikowane wazoaktywne peptydy jelitowe |
| CA2873553C (en) | 2011-06-06 | 2020-01-28 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
| CA2947982C (en) | 2014-05-08 | 2022-11-29 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating cystic fibrosis |
| CA2976038A1 (en) | 2015-02-09 | 2016-08-18 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating muscle disease and disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6429221B1 (en) * | 1994-12-30 | 2002-08-06 | Celgene Corporation | Substituted imides |
-
1998
- 1998-04-17 ES ES009800814A patent/ES2138561B1/es not_active Expired - Fee Related
-
1999
- 1999-04-16 CA CA002294980A patent/CA2294980A1/en not_active Abandoned
- 1999-04-16 AT AT99913324T patent/ATE228006T1/de not_active IP Right Cessation
- 1999-04-16 JP JP55251999A patent/JP2002507224A/ja not_active Ceased
- 1999-04-16 US US09/446,352 patent/US6429188B1/en not_active Expired - Fee Related
- 1999-04-16 AU AU31486/99A patent/AU3148699A/en not_active Abandoned
- 1999-04-16 PT PT99913324T patent/PT1002542E/pt unknown
- 1999-04-16 EP EP99913324A patent/EP1002542B1/de not_active Expired - Lifetime
- 1999-04-16 WO PCT/ES1999/000101 patent/WO1999053944A1/es not_active Ceased
- 1999-04-16 DE DE69904010T patent/DE69904010T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2138561A1 (es) | 2000-01-01 |
| PT1002542E (pt) | 2003-04-30 |
| CA2294980A1 (en) | 1999-10-28 |
| EP1002542A1 (de) | 2000-05-24 |
| JP2002507224A (ja) | 2002-03-05 |
| ES2138561B1 (es) | 2000-07-01 |
| WO1999053944A1 (es) | 1999-10-28 |
| DE69904010T2 (de) | 2003-08-21 |
| DE69904010D1 (de) | 2003-01-02 |
| AU3148699A (en) | 1999-11-08 |
| US6429188B1 (en) | 2002-08-06 |
| EP1002542B1 (de) | 2002-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1002542 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |