ATE230271T1 - Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz - Google Patents

Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Info

Publication number
ATE230271T1
ATE230271T1 AT97906365T AT97906365T ATE230271T1 AT E230271 T1 ATE230271 T1 AT E230271T1 AT 97906365 T AT97906365 T AT 97906365T AT 97906365 T AT97906365 T AT 97906365T AT E230271 T1 ATE230271 T1 AT E230271T1
Authority
AT
Austria
Prior art keywords
outlet tube
enriched fraction
centrifuge
enriched
fraction
Prior art date
Application number
AT97906365T
Other languages
English (en)
Inventor
Peter Unger
Eric Westberg
Original Assignee
Gambro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Inc filed Critical Gambro Inc
Application granted granted Critical
Publication of ATE230271T1 publication Critical patent/ATE230271T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3698—Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT97906365T 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz ATE230271T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600713A SE9600713L (sv) 1996-02-26 1996-02-26 Metod för separering av celler, speciellt blodplättar och pås-set därför
PCT/SE1997/000257 WO1997030715A1 (en) 1996-02-26 1997-02-17 Method for separating cells, especially platelets, and bag assembly therefor

Publications (1)

Publication Number Publication Date
ATE230271T1 true ATE230271T1 (de) 2003-01-15

Family

ID=20401543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97906365T ATE230271T1 (de) 1996-02-26 1997-02-17 Yerfahren zur zellseparation, speziell für thrombozyten, sowie hierfür geeigneter beutelsatz

Country Status (8)

Country Link
US (2) US6315706B1 (de)
EP (1) EP0885007B1 (de)
JP (1) JP4112619B2 (de)
AT (1) ATE230271T1 (de)
AU (1) AU713297B2 (de)
DE (1) DE69718148T2 (de)
SE (1) SE9600713L (de)
WO (1) WO1997030715A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9600713L (sv) 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
SE9700495D0 (sv) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
DE19846535C2 (de) * 1998-10-09 2000-12-07 Westfalia Separator Ag Zentrifuge
SE516321C2 (sv) * 1999-05-31 2001-12-17 Gambro Inc Centrifug för behandling av blod och blodkomponenter
SE517032C2 (sv) 1999-10-26 2002-04-02 Gambro Inc Sätt och anordning för behandling av blod och blodkomponenter
US6890728B2 (en) * 2001-04-09 2005-05-10 Medtronic, Inc. Methods of isolating blood components using a microcentrifuge and uses thereof
EP1476208B1 (de) * 2002-02-01 2011-10-05 CaridianBCT, Inc. System zur entnahme und aufbereitung von vollblut
US7241281B2 (en) * 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US7211191B2 (en) * 2004-09-30 2007-05-01 Thermogenesis Corp. Blood component separation method and apparatus
CA2642653A1 (en) * 2002-04-16 2003-10-30 Gambro Bct, Inc. Blood component processing system, apparatus and method
WO2004018021A2 (en) * 2002-08-23 2004-03-04 Gambro, Inc. Methods and apparatuses for blood component separation
US7347932B2 (en) * 2003-08-25 2008-03-25 Gambro Bct, Inc. Apparatus and method for separating a volume of composite liquid into at least two components
US20070209708A1 (en) * 2004-06-22 2007-09-13 Gambro, Inc. Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it
EP2080531B1 (de) 2004-12-28 2015-09-02 Terumo BCT, Inc. Vorrichtung und Verfahren zur Trennung eines Volumens von Vollblut in mindestens drei Komponenten
US7442178B2 (en) * 2005-03-09 2008-10-28 Jacques Chammas Automated system and method for blood components separation and processing
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
US20100210441A1 (en) * 2005-06-22 2010-08-19 Caridianbct, Inc. Apparatus And Method For Separating Discrete Volumes Of A Composite Liquid
WO2007001739A1 (en) * 2005-06-22 2007-01-04 Gambro Bct, Inc. Apparatus and method for separating discrete volumes of a composite liquid
WO2007024518A2 (en) * 2005-08-22 2007-03-01 Gambro Inc. Apparatus and method for separating a composite liquid into at least two components
BRPI0708019A2 (pt) * 2006-01-30 2011-05-17 Gambro Bct Inc ajuste do ph em um método de sepração de sangue total
WO2007143386A2 (en) * 2006-06-07 2007-12-13 Gambro Bct, Inc. Apparatus and method for separating a composite liquid into at least two components
EP2206527B1 (de) * 2006-09-06 2016-01-27 Terumo BCT, Inc. Vorrichtung und Verfahren zur Trennung einer Flüssigverbindung in mindestens zwei Komponenten
US8016736B2 (en) * 2006-10-20 2011-09-13 Caridianbct Biotechnologies, Llc Methods for washing a red blood cell component and for removing prions therefrom
US20080147240A1 (en) * 2006-12-19 2008-06-19 Gambro Bct Inc. Apparatus for separating a composite liquid with process control on a centrifuge rotor
JP5405313B2 (ja) * 2006-12-20 2014-02-05 テルモ ビーシーティー、インコーポレーテッド 複合液体を少なくとも２つの成分に分離するための機器および方法
US20080234622A1 (en) * 2007-03-20 2008-09-25 Gambro Bct Inc. Methods and Systems for Preparing Blood Products
WO2008140561A1 (en) * 2007-05-14 2008-11-20 Caridianbct, Inc. Apparatus and method for separating a composite liquid into at least two components
US20090272701A1 (en) * 2008-05-02 2009-11-05 Caridianbct, Inc. Centrifuge Apparatus and Method for Selectively Reducing Forces on a Biologic Fluid
WO2010014330A2 (en) * 2008-07-31 2010-02-04 Caridianbct, Inc. Method and apparatus for determining the yield of at least one component
WO2011005411A1 (en) * 2009-07-06 2011-01-13 Caridianbct, Inc. Apparatus and method for automatically loading washing solution in a multi-unit blood processor
DE102010000752A1 (de) * 2010-01-08 2011-07-14 Andreas Hettich GmbH & Co. KG, 78532 Kassette und Systemteil, das in Zusammenwirkung mit der Kassette in einer Zentrifuge einsetzbar ist
CN102946890B (zh) * 2010-03-18 2017-03-08 塞恩根股份有限公司 通过减少净化血液或骨髓中的一些细胞群的系统
US8840535B2 (en) 2010-05-27 2014-09-23 Terumo Bct, Inc. Multi-unit blood processor with temperature sensing
WO2011156068A1 (en) 2010-06-07 2011-12-15 Caridianbct, Inc. Multi-unit blood processor with volume prediction
US9079194B2 (en) 2010-07-19 2015-07-14 Terumo Bct, Inc. Centrifuge for processing blood and blood components
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
WO2014160781A1 (en) 2013-03-26 2014-10-02 Alliance Partners Llc Biological fluids concentration assembly
US10004841B2 (en) 2013-12-09 2018-06-26 Michael C. Larson Blood purifier device and method
WO2015191632A1 (en) 2014-06-10 2015-12-17 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
AU2016338030A1 (en) * 2015-10-14 2018-04-26 Megakaryon Corporation Method for producing purified platelets
US10772916B2 (en) 2016-09-16 2020-09-15 Fenwal, Inc. Systems and methods for deriving and collecting platelet products
IT201900015707A1 (it) * 2019-09-05 2021-03-05 Emotec Srl "dispositivo medico ed apparato per la produzione, a circuito chiuso, di plasma ricco di piastrine e derivati, ad uso non trasfusionale"

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326458A (en) * 1965-05-28 1967-06-20 Harold T Meryman Container and process of storing blood
US3489145A (en) * 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
US3519201A (en) * 1968-05-07 1970-07-07 Us Health Education & Welfare Seal means for blood separator and the like
SE332906B (de) * 1969-08-11 1971-02-22 Aga Ab
JPS50107565A (de) * 1974-01-29 1975-08-25
US4010894A (en) * 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4419089A (en) * 1977-07-19 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Blood cell separator
US4387848A (en) * 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4386730A (en) * 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
SE412528B (sv) * 1978-07-25 1980-03-10 Separex Sa Centrifugrotor och kollaberbar separationsbehallare
JPS59500340A (ja) 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4530691A (en) * 1983-12-13 1985-07-23 Baxter Travenol Laboratories, Inc. Centrifuge with movable mandrel
AU7399787A (en) * 1986-05-16 1987-12-01 Omega Medicinteknik A.B. Method and apparatus for plasmapheresis
SE459791B (sv) 1986-05-16 1989-08-07 Omega Medicinteknik Ab Ringcentrifug
SE454413B (sv) * 1986-09-12 1988-05-02 Alfa Laval Separation Ab Centrifugalseparator med en rotor, vari ett bojligt organ strecker sig ett stycke lengs rotorns omkrets
SE458342B (sv) * 1987-07-06 1989-03-20 Alfa Laval Ab Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar
SE462015B (sv) 1987-09-15 1990-04-30 Omega Medicinteknik Ab Saett och anordning foer tvaettning av blodceller
DE3815645A1 (de) 1988-05-07 1989-11-16 Biotest Pharma Gmbh Verfahren zur herstellung eines reinen thrombozytenkonzentrates aus gesamtblut
US5116308A (en) * 1989-01-13 1992-05-26 Terumo Kabushiki Kaisha Apparatus for processing fluid and method of driving the same
US5209800A (en) * 1990-08-20 1993-05-11 Denco, Inc. Total containment welding of plastic tubes
SE9302369D0 (sv) * 1993-07-08 1993-07-08 Omega Medicinteknik Ab Paassystem avsett foer centrifugalseparationsamt an vaendning av detta paassystem
US5674173A (en) * 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
SE9600713L (sv) 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
SE9700495D0 (sv) * 1997-02-12 1997-02-12 Omega Medicinteknik Ab Metod och rundpåsesystem samt centrifug för behandling av blod
SE9701423D0 (sv) * 1997-04-16 1997-04-16 Omega Medicinteknik Ab Behållarset och anordning för blodseparation

Also Published As

Publication number Publication date
JP4112619B2 (ja) 2008-07-02
AU713297B2 (en) 1999-11-25
DE69718148T2 (de) 2003-10-02
EP0885007B1 (de) 2003-01-02
AU2107997A (en) 1997-09-10
US6855102B2 (en) 2005-02-15
US20020016244A1 (en) 2002-02-07
SE9600713D0 (sv) 1996-02-26
EP0885007A1 (de) 1998-12-23
US6315706B1 (en) 2001-11-13
SE9600713L (sv) 1997-10-17
WO1997030715A1 (en) 1997-08-28
DE69718148D1 (de) 2003-02-06
JP2001517200A (ja) 2001-10-02

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