ATE230278T1 - Mri-mittel zum nachweis von physiologischen mitteln - Google Patents

Mri-mittel zum nachweis von physiologischen mitteln

Info

Publication number
ATE230278T1
ATE230278T1 AT96917061T AT96917061T ATE230278T1 AT E230278 T1 ATE230278 T1 AT E230278T1 AT 96917061 T AT96917061 T AT 96917061T AT 96917061 T AT96917061 T AT 96917061T AT E230278 T1 ATE230278 T1 AT E230278T1
Authority
AT
Austria
Prior art keywords
detecting physiological
physiological agents
chelator
metal ion
mri means
Prior art date
Application number
AT96917061T
Other languages
English (en)
Inventor
Thomas Meade
Scott Fraser
Russell Jacobs
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of ATE230278T1 publication Critical patent/ATE230278T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT96917061T 1995-06-02 1996-06-03 Mri-mittel zum nachweis von physiologischen mitteln ATE230278T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46051195A 1995-06-02 1995-06-02
US08/486,968 US5707605A (en) 1995-06-02 1995-06-07 Magnetic resonance imaging agents for the detection of physiological agents
PCT/US1996/008548 WO1996038184A2 (en) 1995-06-02 1996-06-03 Magnetic resonance imaging agents for the detection of physiological agents

Publications (1)

Publication Number Publication Date
ATE230278T1 true ATE230278T1 (de) 2003-01-15

Family

ID=27039723

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96917061T ATE230278T1 (de) 1995-06-02 1996-06-03 Mri-mittel zum nachweis von physiologischen mitteln

Country Status (10)

Country Link
US (1) US5707605A (de)
EP (1) EP0831928B1 (de)
JP (1) JPH11506455A (de)
AT (1) ATE230278T1 (de)
AU (1) AU712899B2 (de)
CA (1) CA2222974C (de)
DE (1) DE69625595T2 (de)
ES (1) ES2189873T3 (de)
NO (1) NO975517L (de)
WO (1) WO1996038184A2 (de)

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Also Published As

Publication number Publication date
CA2222974A1 (en) 1996-12-05
EP0831928A2 (de) 1998-04-01
DE69625595T2 (de) 2003-11-27
NO975517D0 (no) 1997-12-01
US5707605A (en) 1998-01-13
CA2222974C (en) 2004-05-11
ES2189873T3 (es) 2003-07-16
EP0831928B1 (de) 2003-01-02
DE69625595D1 (de) 2003-02-06
AU712899B2 (en) 1999-11-18
JPH11506455A (ja) 1999-06-08
AU5975196A (en) 1996-12-18
WO1996038184A2 (en) 1996-12-05
WO1996038184A3 (en) 1997-03-13
NO975517L (no) 1998-01-19

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