ATE231559T1 - Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte - Google Patents

Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte

Info

Publication number: ATE231559T1
Authority: AT; Austria
Prior art keywords: nucleic acids; array; rna transcripts; oligonucleotide probes; hybridization
Prior art date: 1995-09-15

Application number

AT96931598T

Other languages

English (en)

Inventor

David J Lockhart

Eugene L Brown

Gordon Wong

Mark Chee

Thomas R Gingeras

Michael P Mittmann

Robert J Lipshutz

Stephen P A Fodor

Chunwei Wang

Original Assignee

Affymetrix Inc A Delaware Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-15

Filing date

1996-09-13

Publication date

2003-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24108589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE231559(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-09-13 Application filed by Affymetrix Inc A Delaware Corp filed Critical Affymetrix Inc A Delaware Corp

2003-02-15 Application granted granted Critical

2003-02-15 Publication of ATE231559T1 publication Critical patent/ATE231559T1/de

Links

108091034117 Oligonucleotide Proteins 0.000 title abstract 5
238000001514 detection method Methods 0.000 title 1
238000009396 hybridization Methods 0.000 title 1
108020004707 nucleic acids Proteins 0.000 abstract 8
150000007523 nucleic acids Chemical class 0.000 abstract 8
102000039446 nucleic acids Human genes 0.000 abstract 8
108020005187 Oligonucleotide Probes Proteins 0.000 abstract 3
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 3
238000000034 method Methods 0.000 abstract 3
239000002751 oligonucleotide probe Substances 0.000 abstract 3
239000000523 sample Substances 0.000 abstract 3
230000000295 complement effect Effects 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
238000012544 monitoring process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

AT96931598T 1995-09-15 1996-09-13 Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte ATE231559T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/529,115 US6040138A (en)	1995-09-15	1995-09-15	Expression monitoring by hybridization to high density oligonucleotide arrays
PCT/US1996/014839 WO1997010365A1 (en)	1995-09-15	1996-09-13	Expression monitoring by hybridization to high density oligonucleotide arrays

Publications (1)

Publication Number	Publication Date
ATE231559T1 true ATE231559T1 (de)	2003-02-15

Family

ID=24108589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96931598T ATE231559T1 (de)	1995-09-15	1996-09-13	Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte

Country Status (8)

Country	Link
US (6)	US6040138A (de)
EP (1)	EP0853679B1 (de)
JP (1)	JPH11512293A (de)
AT (1)	ATE231559T1 (de)
AU (1)	AU7073496A (de)
CA (1)	CA2232047A1 (de)
DE (1)	DE69625920T2 (de)
WO (1)	WO1997010365A1 (de)

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1995
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1996
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- 1996-09-13 AU AU70734/96A patent/AU7073496A/en not_active Abandoned
- 1996-09-13 EP EP96931598A patent/EP0853679B1/de not_active Revoked
- 1996-09-13 AT AT96931598T patent/ATE231559T1/de not_active IP Right Cessation
- 1996-09-13 DE DE69625920T patent/DE69625920T2/de not_active Expired - Lifetime
- 1996-09-13 WO PCT/US1996/014839 patent/WO1997010365A1/en not_active Ceased
- 1996-09-13 JP JP9512174A patent/JPH11512293A/ja not_active Withdrawn
1998
- 1998-12-14 US US09/212,004 patent/US6410229B1/en not_active Expired - Lifetime
2001
- 2001-08-22 US US09/935,365 patent/US6548257B2/en not_active Expired - Lifetime
2003
- 2003-01-28 US US10/353,792 patent/US6927032B2/en not_active Expired - Fee Related
2004
- 2004-11-23 US US10/998,518 patent/US20050158746A1/en not_active Abandoned
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US6548257B2 (en)	2003-04-15
US20050202500A1 (en)	2005-09-15
US20020012940A1 (en)	2002-01-31
EP0853679B1 (de)	2003-01-22
US20030215841A1 (en)	2003-11-20
US20050158746A1 (en)	2005-07-21
DE69625920D1 (de)	2003-02-27
HK1015416A1 (en)	1999-10-15
US6040138A (en)	2000-03-21
CA2232047A1 (en)	1997-03-20
AU7073496A (en)	1997-04-01
US6927032B2 (en)	2005-08-09
EP0853679A1 (de)	1998-07-22
US6410229B1 (en)	2002-06-25
JPH11512293A (ja)	1999-10-26
DE69625920T2 (de)	2003-10-30
WO1997010365A1 (en)	1997-03-20

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