ATE231862T1 - Tetrahydropyridoether - Google Patents

Tetrahydropyridoether

Info

Publication number
ATE231862T1
ATE231862T1 AT99948776T AT99948776T ATE231862T1 AT E231862 T1 ATE231862 T1 AT E231862T1 AT 99948776 T AT99948776 T AT 99948776T AT 99948776 T AT99948776 T AT 99948776T AT E231862 T1 ATE231862 T1 AT E231862T1
Authority
AT
Austria
Prior art keywords
tetrahydropyridoether
naphthyridine
imidazo
methoxyethoxy
tetrahydro
Prior art date
Application number
AT99948776T
Other languages
English (en)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Ernst Sturm
Joerg Senn-Bilfinger
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE231862T1 publication Critical patent/ATE231862T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99948776T 1998-09-23 1999-09-17 Tetrahydropyridoether ATE231862T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
PCT/EP1999/006899 WO2000017200A1 (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Publications (1)

Publication Number Publication Date
ATE231862T1 true ATE231862T1 (de) 2003-02-15

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948776T ATE231862T1 (de) 1998-09-23 1999-09-17 Tetrahydropyridoether

Country Status (31)

Country Link
US (4) US6436953B1 (de)
EP (1) EP1115725B1 (de)
JP (1) JP4145492B2 (de)
KR (1) KR100668400B1 (de)
CN (2) CN100506821C (de)
AT (1) ATE231862T1 (de)
AU (1) AU763463B2 (de)
BG (1) BG65195B1 (de)
BR (1) BR9914044A (de)
CA (1) CA2344251A1 (de)
CZ (1) CZ292335B6 (de)
DE (1) DE69905178T2 (de)
DK (1) DK1115725T3 (de)
EA (1) EA005377B1 (de)
EE (1) EE04677B1 (de)
ES (1) ES2191464T3 (de)
GE (1) GEP20032926B (de)
HK (1) HK1038360B (de)
HR (1) HRP20010224A2 (de)
HU (1) HUP0102990A3 (de)
ID (1) ID28896A (de)
IL (2) IL142063A0 (de)
NO (1) NO317304B1 (de)
NZ (1) NZ510610A (de)
PL (1) PL193616B1 (de)
PT (1) PT1115725E (de)
RS (1) RS50145B (de)
SI (1) SI1115725T1 (de)
SK (1) SK285165B6 (de)
TR (1) TR200100805T2 (de)
WO (1) WO2000017200A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE04677B1 (et) 1998-09-23 2006-08-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahdropridoeetrid, nende kasutamine ja ravim
JP2002542248A (ja) * 1999-04-17 2002-12-10 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ハロアルコキシイミダゾナフチリジン
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
MXPA02009549A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Imidazopiridinas triciclicas.
KR100860627B1 (ko) * 2000-03-29 2008-09-29 니코메드 게엠베하 이미다조피리딘 유도체의 프로드러그
PL360412A1 (en) * 2000-10-25 2004-09-06 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
EP1370261A2 (de) * 2001-03-08 2003-12-17 AstraZeneca AB Neue verwendung
US6927292B2 (en) 2001-08-02 2005-08-09 Altana Pharma Ag Tricyclic epoxides
NZ531433A (en) * 2001-08-03 2005-09-30 Altana Pharma Ag Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders
WO2003014120A1 (en) * 2001-08-03 2003-02-20 Altana Pharma Ag Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
HRP20040834A2 (en) 2002-02-15 2005-06-30 Altana Pharma Ag Tricyclic n-acyl compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1506016A2 (de) * 2002-05-07 2005-02-16 ALTANA Pharma AG Neue kombination von reversiblen protonenpumpenhemmern und atemwegstherapeutika zur behandlung von atemwegserkrankungen
CA2506027A1 (en) 2002-11-19 2004-06-03 Altana Pharma Ag 8-substituted imidazopyridines
ES2312844T3 (es) 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
BR0316752A (pt) * 2002-12-20 2005-10-25 Altana Pharma Ag Silil éteres
BRPI0407541A (pt) * 2003-02-17 2006-02-14 Altana Pharma Ag combinações e uso de compostos farmaceuticamente ativos selecionados
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
JP2006528231A (ja) * 2003-05-27 2006-12-14 アルタナ ファルマ アクチエンゲゼルシャフト プロトンポンプ阻害剤と胃腸運動性を変更する化合物との医薬品組合せ物
BRPI0414046A (pt) * 2003-08-29 2006-10-24 Dynogen Pharmaceuticals Inc método de tratamento de um distúrbio de motilidade gastrintestinal, de tratamento de "gerd", de "gerd" noturno, composição farmacêutica, kit que compreende um composto e método para aumentar a motilidade esofágica em um paciente
AU2004271744B2 (en) 2003-09-16 2010-07-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
EP1682133A1 (de) * 2003-11-03 2006-07-26 AstraZeneca AB Imidazo-1,2-a-pyridin-derivate zur behandlung von beschwerdefreiem gastroösophagealem reflux
EP1697358A1 (de) 2003-12-19 2006-09-06 Altana Pharma AG Zwischenprodukte für die darstellung tricyclischer dihydropyranoimidazopyridinderivate
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
MX2007002214A (es) 2004-09-03 2007-05-07 Yuhan Corp Derivados de pirrolo[3,2-c]piridina y procesos para su preparacion.
KR100958828B1 (ko) 2004-09-03 2010-05-24 주식회사유한양행 피롤로[3,2-b]피리딘 유도체 및 그의 제조방법
DK1784404T3 (da) 2004-09-03 2012-02-13 Yuhan Corp Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP2080513A1 (de) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoether zur Behandlung von AMD
EP2452680B1 (de) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Säurepumpenantagonist zur behandlung von mit unnormalen magen-darm-bewegungen assoziierten erkrankungen
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
WO2013187727A1 (en) * 2012-06-15 2013-12-19 Bio-Pharm Solutions Co., Ltd. Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same
EP3054949A1 (de) 2013-10-08 2016-08-17 Katairo GmbH Tetrahydropyridoether zur behandlung von morbus stargardt

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
KR890701585A (ko) * 1987-07-16 1989-12-21 헤르베르크 슈키·울리히 볼프 새로운 디아졸
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
NZ290819A (en) * 1994-07-28 1998-06-26 Byk Gulden Lomberg Chem Fab Acyl 8-benzyloxy- or 8-benzylaminoimidazopyridines
AU740578B2 (en) * 1997-03-24 2001-11-08 Altana Pharma Ag Tetrahydropyrido compounds
EP0971922B1 (de) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyridoverbindungen
EE04677B1 (et) 1998-09-23 2006-08-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahdropridoeetrid, nende kasutamine ja ravim

Also Published As

Publication number Publication date
AU763463B2 (en) 2003-07-24
SK3992001A3 (en) 2001-12-03
HUP0102990A3 (en) 2002-09-30
SK285165B6 (sk) 2006-07-07
NO317304B1 (no) 2004-10-04
ES2191464T3 (es) 2003-09-01
EE200100172A (et) 2002-06-17
RS50145B (sr) 2009-03-25
NZ510610A (en) 2003-07-25
NO20011243D0 (no) 2001-03-12
SI1115725T1 (en) 2003-06-30
HK1038360A1 (en) 2002-03-15
US20040162310A1 (en) 2004-08-19
CN1560055A (zh) 2005-01-05
CN100506821C (zh) 2009-07-01
US7393860B1 (en) 2008-07-01
GEP20032926B (en) 2003-03-25
KR20010075223A (ko) 2001-08-09
BG105270A (en) 2001-11-30
US7105676B2 (en) 2006-09-12
CZ292335B6 (cs) 2003-09-17
HRP20010224A2 (en) 2002-04-30
AU6192099A (en) 2000-04-10
CZ20011082A3 (cs) 2001-09-12
IL142063A0 (en) 2002-03-10
WO2000017200A1 (en) 2000-03-30
DE69905178D1 (de) 2003-03-06
DK1115725T3 (da) 2003-06-23
TR200100805T2 (tr) 2001-08-21
NO20011243L (no) 2001-03-12
PL346617A1 (en) 2002-02-25
IL142063A (en) 2007-10-31
CN1155598C (zh) 2004-06-30
EP1115725B1 (de) 2003-01-29
HK1038360B (en) 2003-05-16
CA2344251A1 (en) 2000-03-30
EA005377B1 (ru) 2005-02-24
KR100668400B1 (ko) 2007-01-17
BG65195B1 (bg) 2007-06-29
CN1319101A (zh) 2001-10-24
ID28896A (id) 2001-07-12
EE04677B1 (et) 2006-08-15
YU21401A (sh) 2004-03-12
JP2002526499A (ja) 2002-08-20
JP4145492B2 (ja) 2008-09-03
US6696460B2 (en) 2004-02-24
EP1115725A1 (de) 2001-07-18
EA200100315A1 (ru) 2001-10-22
US6436953B1 (en) 2002-08-20
BR9914044A (pt) 2001-12-04
PL193616B1 (pl) 2007-02-28
US20020169320A1 (en) 2002-11-14
HUP0102990A2 (hu) 2002-01-28
DE69905178T2 (de) 2003-07-17
PT1115725E (pt) 2003-06-30

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