ATE233544T1 - Aerosole als darreichungsform mit cfc-freiem treibmittel - Google Patents

Aerosole als darreichungsform mit cfc-freiem treibmittel

Info

Publication number: ATE233544T1
Authority: AT; Austria
Prior art keywords: cfc; aerosols; dosage form; free propellant; propellant
Prior art date: 1993-12-02

Application number

AT95903655T

Other languages

English (en)

Inventor

Akwete L Adjei

Pramod K Gupta

Lu Mou-Ying Fu

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-02

Filing date

1994-12-02

Publication date

2003-03-15

1994-12-02 Application filed by Abbott Lab filed Critical Abbott Lab

2003-03-15 Application granted granted Critical

2003-03-15 Publication of ATE233544T1 publication Critical patent/ATE233544T1/de

Links

239000000443 aerosol Substances 0.000 title abstract 2
239000003380 propellant Substances 0.000 title abstract 2
239000002552 dosage form Substances 0.000 title 1
238000004220 aggregation Methods 0.000 abstract 1
230000002776 aggregation Effects 0.000 abstract 1
KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 abstract 1
239000000084 colloidal system Substances 0.000 abstract 1
239000006184 cosolvent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000001681 protective effect Effects 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Otolaryngology (AREA)
Life Sciences & Earth Sciences (AREA)
Pulmonology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT95903655T 1993-12-02 1994-12-02 Aerosole als darreichungsform mit cfc-freiem treibmittel ATE233544T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16111593A	1993-12-02	1993-12-02
PCT/US1994/013791 WO1995015151A1 (en)	1993-12-02	1994-12-02	Aerosol drug formulations for use with non-cfc propellants

Publications (1)

Publication Number	Publication Date
ATE233544T1 true ATE233544T1 (de)	2003-03-15

Family

ID=22579887

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95903655T ATE233544T1 (de)	1993-12-02	1994-12-02	Aerosole als darreichungsform mit cfc-freiem treibmittel

Country Status (10)

Country	Link
US (1)	US5676931A (de)
EP (1)	EP0731688B1 (de)
JP (1)	JPH09506097A (de)
AT (1)	ATE233544T1 (de)
CA (1)	CA2176249C (de)
DE (1)	DE69432224T2 (de)
DK (1)	DK0731688T3 (de)
ES (1)	ES2193186T3 (de)
PT (1)	PT731688E (de)
WO (1)	WO1995015151A1 (de)

Families Citing this family (49)

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JP3026841B2 (ja) *	1991-12-12	2000-03-27	グラクソ、グループ、リミテッド	医薬
JP4155594B2 (ja) *	1994-12-22	2008-09-24	アストラゼネカ・アクチエボラーグ	エアゾール製剤
US6039932A (en) *	1996-09-27	2000-03-21	3M Innovative Properties Company	Medicinal inhalation aerosol formulations containing budesonide
US6126919A (en)	1997-02-07	2000-10-03	3M Innovative Properties Company	Biocompatible compounds for pharmaceutical drug delivery systems
US6193954B1 (en)	1997-03-21	2001-02-27	Abbott Laboratories	Formulations for pulmonary delivery of dopamine agonists
US5891419A (en) *	1997-04-21	1999-04-06	Aeropharm Technology Limited	Environmentally safe flunisolide aerosol formulations for oral inhalation
US5891420A (en) *	1997-04-21	1999-04-06	Aeropharm Technology Limited	Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation
US6129905A (en) *	1997-04-21	2000-10-10	Aeropharm Technology, Inc.	Aerosol formulations containing a sugar as a dispersant
US6284225B1 (en) *	1997-09-29	2001-09-04	Helene Curtis, Inc.	Propellant compositions comprising a hydrofluorocarbon and a hydrocarbon
US20060165606A1 (en) *	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6221378B1 (en)	1998-02-10	2001-04-24	Generex Pharmaceuticals Incorporated	Mixed micellar delivery system and method of preparation
US7070799B1 (en) *	1998-02-10	2006-07-04	Generex Pharmaceuticals, Inc.	Method for administering insulin to the buccal region
US6350458B1 (en)	1998-02-10	2002-02-26	Generex Pharmaceuticals Incorporated	Mixed micellar drug deliver system and method of preparation
US6458338B1 (en) *	1998-09-22	2002-10-01	Aeropharm Technology Incorporated	Amino acid stabilized medicinal aerosol formulations
US6136294C1 (en) *	1998-09-22	2002-09-24	Aeropharm Technology Inc	Amino acid stabilized medical aerosol formulation
CN1150895C (zh)	1998-11-13	2004-05-26	杰格研究股份公司	用于吸入给药的干粉
US20070212422A1 (en) *	1999-11-10	2007-09-13	Manfred Keller	Dry powder for inhalation
US6294153B1 (en)	1998-12-21	2001-09-25	Generex Pharmaceuticals, Inc.	Aerosol pharmaceutical formulation for pulmonary and nasal delivery
US6350432B1 (en)	1999-03-19	2002-02-26	Generex Pharmaceuticals Incorporated	Pressurized container having an aerosolized pharmaceutical composition
AU5936400A (en)	1999-06-04	2000-12-28	Delrx Pharmaceutical Corporation	Formulations comprising dehydrated particles of pharmaceutical agents and process for preparing the same
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt)	2000-05-10	2014-12-16	Novartis Ag	Pós à base de fosfolípidos para administração de fármacos
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US20030003057A1 (en) *	2000-07-07	2003-01-02	Jeffry Weers	Methods for administering leuprolide by inhalation
WO2002007672A2 (en) *	2000-07-19	2002-01-31	Aeropharm Technology, Inc.	A medicinal aerosol formulation
CN100496608C (zh) *	2001-03-30	2009-06-10	洁垢技术有限公司	药用气溶胶制剂
TWI324518B (en) *	2001-12-19	2010-05-11	Nektar Therapeutics	Pulmonary delivery of aminoglycosides
EP1458354A1 (de) *	2001-12-21	2004-09-22	3M Innovative Properties Company	Ionenpaarkomplexe enthaltende medizinische aerosolzusammensetzung
EP1458357B1 (de) *	2001-12-21	2009-03-04	3M Innovative Properties Company	Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff
CA2470498A1 (en) *	2001-12-21	2003-07-24	3M Innovative Properties Company	Medicinal aerosol compositions with an amide and/or ester containing excipient compound
GB0226274D0 (en) *	2002-11-11	2002-12-18	Medpharm Ltd	Metered dose inhalation preparations
US20040242729A1 (en) *	2003-05-30	2004-12-02	3M Innovative Properties Company	Stabilized particle dispersions containing surface-modified inorganic nanoparticles
US7459146B2 (en)	2003-05-30	2008-12-02	3M Innovative Properties Company	Stabilized aerosol dispersions
GB0323684D0 (en)	2003-10-09	2003-11-12	Jagotec Ag	Improvements in or relating to organic compounds
GB0328630D0 (en) *	2003-12-10	2004-01-14	Medpharm Ltd	Metered dose inhalation preparations
HUE026152T2 (en)	2004-04-23	2016-05-30	Philip Morris Products Sa	Aerosol Generator and Method for Aerosol Production
WO2007008427A2 (en) *	2005-07-08	2007-01-18	Xemplar Pharmaceuticals, Llc	Aerosol compositions and methods
GB0518769D0 (en)	2005-09-14	2005-10-19	Medpharm Ltd	Topical formulations
US20070286814A1 (en) *	2006-06-12	2007-12-13	Medispray Laboratories Pvt. Ltd.	Stable aerosol pharmaceutical formulations
GB0614621D0 (en)	2006-07-24	2006-08-30	3M Innovative Properties Co	Metered dose dispensers
GB0620700D0 (en)	2006-10-19	2006-11-29	3M Innovative Properties Co	Metered dose valves and dispensers
PT2435025T (pt)	2009-05-29	2016-11-11	Pearl Therapeutics Inc	Administração, por via respiratória, de agentes activos
US8815258B2 (en)	2009-05-29	2014-08-26	Pearl Therapeutics, Inc.	Compositions, methods and systems for respiratory delivery of two or more active agents
GB0918149D0 (en)	2009-10-16	2009-12-02	Jagotec Ag	Improved medicinal aerosol formulation
GB201118188D0 (en)	2011-10-21	2011-12-07	3M Innovative Properties Co	Manufacture of medicinal aerosol canisters
GB201210580D0 (en)	2012-06-14	2012-08-01	3M Innovative Properties Co	Metered dose dispensing valve
GB201221063D0 (en)	2012-11-23	2013-01-09	3M Innovative Properties Co	Metered dose dispensing valve
JP6454323B2 (ja)	2013-03-15	2019-01-16	パールセラピューティクス，インコーポレイテッド	粒子状結晶性材料のコンディショニングのための方法及びシステム
GB201306984D0 (en) *	2013-04-17	2013-05-29	Mexichem Amanco Holding Sa	Composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5225183A (en) *	1988-12-06	1993-07-06	Riker Laboratories, Inc.	Medicinal aerosol formulations
IL97065A (en) *	1990-02-02	1994-01-25	Fisons Plc	Repellent preparations for aerosol
CA2083821A1 (en) *	1990-06-28	1991-12-29	Keith A. Johnson	Aerosol drug formulations
JP2854974B2 (ja) *	1990-06-29	1999-02-10	フアイソンズ・ピーエルシー	加圧エアロゾル組成物
US5230884A (en) *	1990-09-11	1993-07-27	University Of Wales College Of Cardiff	Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations
GB9024366D0 (en) *	1990-11-09	1991-01-02	Glaxo Group Ltd	Medicaments
US5182097A (en) *	1991-02-14	1993-01-26	Virginia Commonwealth University	Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5202110A (en) *	1992-01-22	1993-04-13	Virginia Commonwealth University	Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants

1994
- 1994-12-02 JP JP7515752A patent/JPH09506097A/ja not_active Ceased
- 1994-12-02 DK DK95903655T patent/DK0731688T3/da active
- 1994-12-02 PT PT95903655T patent/PT731688E/pt unknown
- 1994-12-02 AT AT95903655T patent/ATE233544T1/de active
- 1994-12-02 CA CA2176249A patent/CA2176249C/en not_active Expired - Lifetime
- 1994-12-02 WO PCT/US1994/013791 patent/WO1995015151A1/en not_active Ceased
- 1994-12-02 ES ES95903655T patent/ES2193186T3/es not_active Expired - Lifetime
- 1994-12-02 DE DE69432224T patent/DE69432224T2/de not_active Expired - Lifetime
- 1994-12-02 EP EP95903655A patent/EP0731688B1/de not_active Expired - Lifetime
1996
- 1996-05-15 US US08/655,275 patent/US5676931A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1995015151A1 (en)	1995-06-08
JPH09506097A (ja)	1997-06-17
EP0731688B1 (de)	2003-03-05
EP0731688A1 (de)	1996-09-18
ES2193186T3 (es)	2003-11-01
DE69432224D1 (de)	2003-04-10
DK0731688T3 (da)	2003-06-23
CA2176249A1 (en)	1995-06-08
PT731688E (pt)	2003-07-31
CA2176249C (en)	2010-06-01
US5676931A (en)	1997-10-14
DE69432224T2 (de)	2003-12-04

Legal Events

Date

Code

Title

Description

2003-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0731688

Country of ref document: EP

Publication	Publication Date	Title
DE69432224D1 (de)	2003-04-10	Aerosole als darreichungsform mit cfc-freiem treibmittel
WO1996040089A3 (en)	1997-01-23	Aerosol drug formulations containing vegetable oils
ATE162072T1 (de)	1998-01-15	Kleine partikeln enthaltende arzneistoffzusammensetzung
DE69231992D1 (de)	2001-09-13	Fluorchlorkohlenwasserstofffreie Aerosolformulierungen
DK0616525T3 (da)	1996-01-08	Medikamenter
GEP20012462B (en)	2001-06-25	Composition for Aerosol Inhaler, Aerosol Inhaler and Method for Filling with the Composition
SE0002643D0 (sv)	2000-07-13	Microparticle inhalation formulations
AU4260496A (en)	1996-07-03	Propellant mixture for aerosol formulation
EA199900991A1 (ru)	2000-08-28	Медицинские аэрозольные препараты
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