ATE233758T1 - Ethylthiophen-thioharnstoff-derivate und ihre verwendung - Google Patents
Ethylthiophen-thioharnstoff-derivate und ihre verwendungInfo
- Publication number
- ATE233758T1 ATE233758T1 AT00941686T AT00941686T ATE233758T1 AT E233758 T1 ATE233758 T1 AT E233758T1 AT 00941686 T AT00941686 T AT 00941686T AT 00941686 T AT00941686 T AT 00941686T AT E233758 T1 ATE233758 T1 AT E233758T1
- Authority
- AT
- Austria
- Prior art keywords
- ethylthiophene
- drug
- thiourea derivatives
- thiourea
- hiv
- Prior art date
Links
- -1 ETHYLTHIOPHENE-THIOUREA DERIVATIVES Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 102100034343 Integrase Human genes 0.000 abstract 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- IKSDOGDJZGKXBF-UHFFFAOYSA-N ethylthiourea;thiophene Chemical compound C=1C=CSC=1.CCNC(N)=S IKSDOGDJZGKXBF-UHFFFAOYSA-N 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/338,685 US6124324A (en) | 1999-06-23 | 1999-06-23 | Thiophene-ethyl thiourea compounds and use |
| PCT/US2000/017361 WO2000078755A1 (en) | 1999-06-23 | 2000-06-23 | Thiophene-ethyl thiourea compounds and use in the treatment of hiv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233758T1 true ATE233758T1 (de) | 2003-03-15 |
Family
ID=23325726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00941686T ATE233758T1 (de) | 1999-06-23 | 2000-06-23 | Ethylthiophen-thioharnstoff-derivate und ihre verwendung |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6124324A (de) |
| EP (1) | EP1194427B1 (de) |
| JP (1) | JP2003502423A (de) |
| KR (1) | KR20020012287A (de) |
| CN (1) | CN1196697C (de) |
| AT (1) | ATE233758T1 (de) |
| AU (2) | AU6539900A (de) |
| BR (1) | BR0009102A (de) |
| CA (1) | CA2375261A1 (de) |
| DE (1) | DE60001581T2 (de) |
| ES (1) | ES2195905T3 (de) |
| IL (1) | IL144874A0 (de) |
| MX (1) | MXPA01009283A (de) |
| WO (2) | WO2000078756A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002032873A1 (en) * | 2000-10-18 | 2002-04-25 | Parker Hughes Institute | Phenoxyethyl-thiourea-pyridine compounds and their use for the treatment of hiv-infections |
| SE0100733D0 (sv) | 2001-03-05 | 2001-03-05 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| SE0102867D0 (sv) | 2001-08-28 | 2001-08-28 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| US7642277B2 (en) | 2002-12-04 | 2010-01-05 | Boehringer Ingelheim International Gmbh | Non-nucleoside reverse transcriptase inhibitors |
| WO2022107450A1 (ja) * | 2020-11-17 | 2022-05-27 | パナソニックＩｐマネジメント株式会社 | 固体電解質、電池および固体電解質の製造方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686428A (en) * | 1989-04-07 | 1997-11-11 | Aktiebolaget Astra | Pharmaceutical composition |
| US5593993A (en) * | 1991-08-02 | 1997-01-14 | Medivir Ab | Method for inhibition of HIV related viruses |
| IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds |
-
1999
- 1999-06-23 US US09/338,685 patent/US6124324A/en not_active Expired - Fee Related
-
2000
- 2000-06-15 AU AU65399/00A patent/AU6539900A/en not_active Abandoned
- 2000-06-15 WO PCT/US2000/040203 patent/WO2000078756A1/en not_active Ceased
- 2000-06-23 AT AT00941686T patent/ATE233758T1/de not_active IP Right Cessation
- 2000-06-23 CA CA002375261A patent/CA2375261A1/en not_active Abandoned
- 2000-06-23 AU AU56358/00A patent/AU5635800A/en not_active Abandoned
- 2000-06-23 BR BR0009102-2A patent/BR0009102A/pt not_active Application Discontinuation
- 2000-06-23 JP JP2001504921A patent/JP2003502423A/ja not_active Withdrawn
- 2000-06-23 KR KR1020017016434A patent/KR20020012287A/ko not_active Withdrawn
- 2000-06-23 MX MXPA01009283A patent/MXPA01009283A/es unknown
- 2000-06-23 CN CNB008091129A patent/CN1196697C/zh not_active Expired - Fee Related
- 2000-06-23 WO PCT/US2000/017361 patent/WO2000078755A1/en not_active Ceased
- 2000-06-23 DE DE60001581T patent/DE60001581T2/de not_active Expired - Fee Related
- 2000-06-23 IL IL14487400A patent/IL144874A0/xx unknown
- 2000-06-23 ES ES00941686T patent/ES2195905T3/es not_active Expired - Lifetime
- 2000-06-23 EP EP00941686A patent/EP1194427B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2195905T3 (es) | 2003-12-16 |
| KR20020012287A (ko) | 2002-02-15 |
| WO2000078755A1 (en) | 2000-12-28 |
| IL144874A0 (en) | 2002-06-30 |
| EP1194427A1 (de) | 2002-04-10 |
| BR0009102A (pt) | 2002-01-08 |
| JP2003502423A (ja) | 2003-01-21 |
| WO2000078756A1 (en) | 2000-12-28 |
| MXPA01009283A (es) | 2002-04-10 |
| AU6539900A (en) | 2001-01-09 |
| CN1356997A (zh) | 2002-07-03 |
| CA2375261A1 (en) | 2000-12-28 |
| AU5635800A (en) | 2001-01-09 |
| DE60001581D1 (de) | 2003-04-10 |
| DE60001581T2 (de) | 2004-02-19 |
| US6124324A (en) | 2000-09-26 |
| CN1196697C (zh) | 2005-04-13 |
| EP1194427B1 (de) | 2003-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |