ATE234296T1 - Verfahren zur herstellung von (8-chloro-3,10- dibromo-6,11-dihydro-5h-benzo(5,6) cyclohepta(1,2-b)pyridin-11-yl)-1-piperidin - Google Patents

Verfahren zur herstellung von (8-chloro-3,10- dibromo-6,11-dihydro-5h-benzo(5,6) cyclohepta(1,2-b)pyridin-11-yl)-1-piperidin

Info

Publication number
ATE234296T1
ATE234296T1 AT99931864T AT99931864T ATE234296T1 AT E234296 T1 ATE234296 T1 AT E234296T1 AT 99931864 T AT99931864 T AT 99931864T AT 99931864 T AT99931864 T AT 99931864T AT E234296 T1 ATE234296 T1 AT E234296T1
Authority
AT
Austria
Prior art keywords
formula
producing
cyclohepta
dibromo
benzo
Prior art date
Application number
AT99931864T
Other languages
English (en)
Inventor
F George Njoroge
Bancha Vibulbhan
Viyyoor M Girijavallabhan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE234296T1 publication Critical patent/ATE234296T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B35/00Reactions without formation or introduction of functional groups containing hetero atoms, involving a change in the type of bonding between two carbon atoms already directly linked
    • C07B35/02Reduction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00Racemisation; Complete or partial inversion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99931864T 1998-07-02 1999-07-01 Verfahren zur herstellung von (8-chloro-3,10- dibromo-6,11-dihydro-5h-benzo(5,6) cyclohepta(1,2-b)pyridin-11-yl)-1-piperidin ATE234296T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10936598A 1998-07-02 1998-07-02
PCT/US1999/014122 WO2000001689A1 (en) 1998-07-02 1999-07-01 Process for producing (8- chloro-3,10- dibromo-6,11- dihydro- 5h-benzo [5,6]cyclohepta [1,2-b]pyridin-11-yl)- 1-piperidine

Publications (1)

Publication Number Publication Date
ATE234296T1 true ATE234296T1 (de) 2003-03-15

Family

ID=22327275

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99931864T ATE234296T1 (de) 1998-07-02 1999-07-01 Verfahren zur herstellung von (8-chloro-3,10- dibromo-6,11-dihydro-5h-benzo(5,6) cyclohepta(1,2-b)pyridin-11-yl)-1-piperidin

Country Status (8)

Country Link
EP (1) EP1091954B1 (de)
JP (1) JP2002519419A (de)
AT (1) ATE234296T1 (de)
AU (1) AU4828299A (de)
CA (1) CA2335967A1 (de)
DE (1) DE69905891T2 (de)
ES (1) ES2190227T3 (de)
WO (1) WO2000001689A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7892840B2 (en) 2008-12-30 2011-02-22 Medtronic Minimed, Inc. Media compositions for eluting compounds from matrices and methods for making and using them
US8372646B1 (en) 2009-12-21 2013-02-12 Medtronic Minimed, Inc. Terpene media compositions for eluting compounds from matrices and methods for making and using them
FR3156046A1 (fr) * 2023-12-01 2025-06-06 Finorga Procédé de production d’un composé chimique atropoisomère

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL125062A (en) * 1995-12-22 2003-11-23 Schering Corp Tricyclic amides and pharmaceutical compositions containing them for inhibition of g-protein function and for treatment of proliferative diseases
IN187248B (de) * 1997-06-17 2002-03-09 Schering Corp

Also Published As

Publication number Publication date
DE69905891D1 (de) 2003-04-17
JP2002519419A (ja) 2002-07-02
ES2190227T3 (es) 2003-07-16
DE69905891T2 (de) 2003-11-20
CA2335967A1 (en) 2000-01-13
EP1091954A1 (de) 2001-04-18
AU4828299A (en) 2000-01-24
EP1091954B1 (de) 2003-03-12
WO2000001689A1 (en) 2000-01-13

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