ATE236251T1 - Anti-menschliche milchfettglobule humanisierte antikörper und verfahren zu ihrer herstellung - Google Patents
Anti-menschliche milchfettglobule humanisierte antikörper und verfahren zu ihrer herstellungInfo
- Publication number
- ATE236251T1 ATE236251T1 AT97200482T AT97200482T ATE236251T1 AT E236251 T1 ATE236251 T1 AT E236251T1 AT 97200482 T AT97200482 T AT 97200482T AT 97200482 T AT97200482 T AT 97200482T AT E236251 T1 ATE236251 T1 AT E236251T1
- Authority
- AT
- Austria
- Prior art keywords
- hams
- derived
- milk fat
- human milk
- globles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919120467A GB9120467D0 (en) | 1991-09-26 | 1991-09-26 | Anti-hmfg antibodies and process for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236251T1 true ATE236251T1 (de) | 2003-04-15 |
Family
ID=10701993
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97200482T ATE236251T1 (de) | 1991-09-26 | 1992-09-24 | Anti-menschliche milchfettglobule humanisierte antikörper und verfahren zu ihrer herstellung |
| AT92308680T ATE160362T1 (de) | 1991-09-26 | 1992-09-24 | Anti-menschliche milchfettglobule humanisierte antikörper |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92308680T ATE160362T1 (de) | 1991-09-26 | 1992-09-24 | Anti-menschliche milchfettglobule humanisierte antikörper |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6506881B1 (de) |
| EP (2) | EP0781845B1 (de) |
| JP (1) | JP3498957B2 (de) |
| AT (2) | ATE236251T1 (de) |
| AU (1) | AU666868B2 (de) |
| CA (1) | CA2095926C (de) |
| DE (2) | DE69232991T2 (de) |
| DK (1) | DK0781845T3 (de) |
| ES (1) | ES2108732T3 (de) |
| GB (1) | GB9120467D0 (de) |
| IL (1) | IL103269A (de) |
| NZ (1) | NZ244468A (de) |
| WO (1) | WO1993006231A1 (de) |
Families Citing this family (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1994011508A2 (en) * | 1992-11-13 | 1994-05-26 | Cancer Research Fund Of Contra Costa | Polypeptides with specificity for neoplasias, kit, and diagnostic, vaccination, and therapeutic methods |
| US6281335B1 (en) * | 1993-10-08 | 2001-08-28 | Coulter Corporation | Hybridoma and anti-KC-4 humanized monoclonal antibody |
| WO1994011509A2 (en) * | 1992-11-16 | 1994-05-26 | Cancer Research Fund Of Contra Costa | Peptides and anti-sense peptides with broad neoplastic specificity |
| US6074642A (en) * | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| US5773001A (en) * | 1994-06-03 | 1998-06-30 | American Cyanamid Company | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis |
| AU707159B2 (en) * | 1994-09-16 | 1999-07-01 | Cancer Research Fund Of Contra Costa | Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides |
| US5712374A (en) * | 1995-06-07 | 1998-01-27 | American Cyanamid Company | Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates |
| US7361336B1 (en) * | 1997-09-18 | 2008-04-22 | Ivan Bergstein | Methods of cancer therapy targeted against a cancer stem line |
| GB9812545D0 (en) | 1998-06-10 | 1998-08-05 | Celltech Therapeutics Ltd | Biological products |
| DE69942782D1 (de) | 1998-11-27 | 2010-10-28 | Ucb Sa | Zusammensetzungen und Verfahren zur Erhöhung der Knochenmineralisierung |
| US20040009535A1 (en) | 1998-11-27 | 2004-01-15 | Celltech R&D, Inc. | Compositions and methods for increasing bone mineralization |
| GB2360771A (en) * | 2000-03-28 | 2001-10-03 | Antisoma Res Ltd | Compounds for targeting |
| WO2001074905A1 (en) * | 2000-04-03 | 2001-10-11 | Antisoma Research Limited | Compounds for targeting |
| PT1283214E (pt) | 2000-04-21 | 2007-03-30 | Fuso Pharmaceutical Ind | Novas colectinas |
| GB0013810D0 (en) | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| AU2002251913A1 (en) * | 2001-02-02 | 2002-08-19 | Millennium Pharmaceuticals, Inc. | Hybrid antibodies and uses thereof |
| US6441163B1 (en) * | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| GB0124317D0 (en) | 2001-10-10 | 2001-11-28 | Celltech R&D Ltd | Biological products |
| WO2003099226A2 (en) | 2002-05-28 | 2003-12-04 | Celltech R & D Limited | Antibody peg positional isomers, compositions comprising same, and use thereof |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| JP5183484B2 (ja) | 2005-12-09 | 2013-04-17 | ユセベ ファルマ ソシエテ アノニム | ヒトｉｌ−６に対して特異性を有する抗体分子 |
| JP2009529917A (ja) | 2006-03-22 | 2009-08-27 | ヴァイラル ロジック システムズ テクノロジー コーポレーション | 標的ポリペプチドの同定方法および免疫学的疾患の治療のためのその使用 |
| US8377448B2 (en) | 2006-05-15 | 2013-02-19 | The Board Of Trustees Of The Leland Standford Junior University | CD47 related compositions and methods for treating immunological diseases and disorders |
| US20080118518A1 (en) * | 2006-09-07 | 2008-05-22 | Cirrito Thomas P | Cancer stem cell-targeted cancer therapy |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| US9226934B2 (en) * | 2008-06-02 | 2016-01-05 | The University Of Tokyo | Anti-cancer drug |
| EP2145901B1 (de) * | 2008-07-18 | 2012-11-14 | Technische Universität Braunschweig | Rekombinante anti-MUC1-Antikörper |
| EP2398498B1 (de) | 2009-02-17 | 2018-09-05 | UCB Biopharma SPRL | Für humanes ox40 spezifische antikörpermoleküle |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| ES2667258T3 (es) | 2009-09-10 | 2018-05-10 | Ucb Biopharma Sprl | Anticuerpos multivalentes |
| GB0920127D0 (en) | 2009-11-17 | 2009-12-30 | Ucb Pharma Sa | Antibodies |
| GB0920324D0 (en) | 2009-11-19 | 2010-01-06 | Ucb Pharma Sa | Antibodies |
| GB201000467D0 (en) | 2010-01-12 | 2010-02-24 | Ucb Pharma Sa | Antibodies |
| CA2791930A1 (en) | 2010-03-11 | 2011-09-15 | Kerry Louise Tyson | Pd-1 antibody |
| TW201134488A (en) | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| GB201005064D0 (en) | 2010-03-25 | 2010-05-12 | Ucb Pharma Sa | Biological products |
| ES2717883T3 (es) | 2010-03-25 | 2019-06-26 | Ucb Biopharma Sprl | Moléculas de DVD-LG estabilizadas con disulfuro |
| GB201012599D0 (en) | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Process for purifying proteins |
| GB201014033D0 (en) | 2010-08-20 | 2010-10-06 | Ucb Pharma Sa | Biological products |
| ME02734B (de) | 2011-01-14 | 2017-10-20 | Ucb Biopharma Sprl | Antikörpermodule zur bindung an il-17a und il-17f |
| US10752676B2 (en) | 2011-09-16 | 2020-08-25 | Ucb Biopharma Sprl | Neutralising antibodies to the major exotoxins TCDA and TCDB of Clostridium difficile |
| UA112203C2 (uk) | 2011-11-11 | 2016-08-10 | Юсб Фарма С.А. | Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини |
| GB201203051D0 (en) | 2012-02-22 | 2012-04-04 | Ucb Pharma Sa | Biological products |
| GB201203071D0 (en) | 2012-02-22 | 2012-04-04 | Ucb Pharma Sa | Biological products |
| GB201208370D0 (en) | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Antibodies |
| GB201223276D0 (en) | 2012-12-21 | 2013-02-06 | Ucb Pharma Sa | Antibodies and methods of producing same |
| GB201315487D0 (en) | 2013-08-30 | 2013-10-16 | Ucb Pharma Sa | Antibodies |
| GB201320066D0 (en) | 2013-11-13 | 2013-12-25 | Ucb Pharma Sa | Biological products |
| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| GB201411320D0 (en) | 2014-06-25 | 2014-08-06 | Ucb Biopharma Sprl | Antibody construct |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201506870D0 (en) | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
| GB201506869D0 (en) | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
| JP2018515082A (ja) | 2015-04-30 | 2018-06-14 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 代謝障害を処置するための抗ａｐ２抗体及び抗原結合剤 |
| GB201508180D0 (en) | 2015-05-13 | 2015-06-24 | Ucb Biopharma Sprl | Antibodies |
| CN113940996A (zh) | 2015-05-27 | 2022-01-18 | Ucb生物制药私人有限公司 | 用于治疗神经系统疾病的方法 |
| MA41670A1 (fr) | 2015-07-06 | 2018-05-31 | Ucb Biopharma Sprl | Anticorps se liant a tau |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| RU2754683C2 (ru) | 2015-10-27 | 2021-09-06 | Юсб Биофарма Срл | Способы лечения с использованием анти-il-17a антител |
| GB201521393D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201522394D0 (en) | 2015-12-18 | 2016-02-03 | Ucb Biopharma Sprl | Antibodies |
| WO2017213695A1 (en) | 2016-06-07 | 2017-12-14 | The Brigham And Women's Hospital, Inc. | Compositions and methods relating to t peripheral helper cells in autoantibody-associated conditions |
| GB201610198D0 (en) | 2016-06-10 | 2016-07-27 | Ucb Biopharma Sprl | Anti-ige antibodies |
| SG10201913858WA (en) | 2016-08-26 | 2020-03-30 | Agency Science Tech & Res | Macrophage stimulating protein receptor (or ron - recepteur d' origine nantais) antibodies and uses thereof |
| GB201616596D0 (en) | 2016-09-29 | 2016-11-16 | Nascient Limited | Epitope and antibodies |
| GB201621635D0 (en) | 2016-12-19 | 2017-02-01 | Ucb Biopharma Sprl | Crystal structure |
| WO2018183366A1 (en) | 2017-03-28 | 2018-10-04 | Syndax Pharmaceuticals, Inc. | Combination therapies of csf-1r or csf-1 antibodies and a t-cell engaging therapy |
| JP7537874B2 (ja) | 2017-05-19 | 2024-08-21 | シンダックス ファーマシューティカルズ， インコーポレイテッド | 併用療法 |
| GB201802486D0 (en) | 2018-02-15 | 2018-04-04 | Ucb Biopharma Sprl | Methods |
| PT3806898T (pt) | 2018-06-18 | 2025-12-02 | UCB Biopharma SRL | Antagonista de gremlin-1 para utilização no tratamento do cancro |
| KR20260014044A (ko) | 2018-10-16 | 2026-01-29 | 유씨비 바이오파마 에스알엘 | 중증근무력증의 치료 방법 |
| EP3947457A1 (de) | 2019-03-26 | 2022-02-09 | ASLAN Pharmaceuticals Pte Ltd | Behandlung mit verwendung von anti-il-13r-antikörper oder bindefragment davon |
| GB201919058D0 (en) | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Multi-specific antibodies |
| GB201919062D0 (en) | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Antibody |
| GB201919061D0 (en) | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Multi-specific antibody |
| GB202001447D0 (en) | 2020-02-03 | 2020-03-18 | Ucb Biopharma Sprl | Antibodies |
| JP2023547795A (ja) | 2020-10-15 | 2023-11-14 | ユーシービー バイオファルマ エスアールエル | Ｃｄ４５を多量体化する結合分子 |
| WO2022089767A1 (en) | 2020-11-02 | 2022-05-05 | UCB Biopharma SRL | Use of anti-trem1 neutralizing antibodies for the treatment of motor neuron neurodegenerative disorders |
| KR20230118128A (ko) | 2020-12-07 | 2023-08-10 | 유씨비 바이오파마 에스알엘 | 인터루킨-22에 대한 항체 |
| EP4255926A1 (de) | 2020-12-07 | 2023-10-11 | UCB Biopharma SRL | Multispezifische antikörper und antikörperkombinationen |
| WO2022186772A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
| WO2022186773A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF IN AN ALLERGIC POPULATION |
| EP4067381A1 (de) | 2021-04-01 | 2022-10-05 | Julius-Maximilians-Universität Würzburg | Neue tnfr2-bindende moleküle |
| JP2024516305A (ja) | 2021-05-03 | 2024-04-12 | ユーシービー バイオファルマ エスアールエル | 抗体 |
| GB202111905D0 (en) | 2021-08-19 | 2021-10-06 | UCB Biopharma SRL | Antibodies |
| WO2023048650A1 (en) | 2021-09-27 | 2023-03-30 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF PRURITIS EMPLOYING ANTI-IL13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
| WO2023048651A1 (en) | 2021-09-27 | 2023-03-30 | Aslan Pharmaceuticals Pte Ltd | Method for treatment of moderate to severe atoptic dematitis |
| GB202115122D0 (en) | 2021-10-21 | 2021-12-08 | Dualyx Nv | Binding molecules targeting IL-2 receptor |
| WO2023075702A1 (en) | 2021-10-29 | 2023-05-04 | Aslan Pharmaceuticals Pte Ltd | Anti-il-13r antibody formulation |
| WO2023140780A1 (en) | 2022-01-24 | 2023-07-27 | Aslan Pharmaceuticals Pte Ltd. | Method of treating inflammatory disease |
| TW202337905A (zh) | 2022-02-23 | 2023-10-01 | 新加坡商亞獅康私人有限公司 | 抗il13r抗體之糖基化形式 |
| GB202210679D0 (en) | 2022-07-21 | 2022-09-07 | Dualyx Nv | Binding molecules targeting il-12rb2 |
| EP4590335A1 (de) | 2022-08-26 | 2025-07-30 | ASLAN Pharmaceuticals Pte Ltd | Hochkonzentrierte anti-il13r-antikörperformulierung |
| EP4594352A1 (de) | 2022-09-06 | 2025-08-06 | ASLAN Pharmaceuticals Pte Ltd | Behandlung von schlafverlust oder schlafstörung bei dermatitispatienten |
| GB202318820D0 (en) | 2023-12-08 | 2024-01-24 | UCB Biopharma SRL | Antibodies |
| WO2025238133A1 (en) | 2024-05-17 | 2025-11-20 | UCB Biopharma SRL | Multispecific antibody with binding specificity for il-11 and il-17 |
| WO2025238135A2 (en) | 2024-05-17 | 2025-11-20 | UCB Biopharma SRL | Antibody with binding specificity for il-11 |
| WO2026027660A1 (en) | 2024-08-02 | 2026-02-05 | UCB Biopharma SRL | Formulations of anti-gremlin-1 antibodies |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2584293B1 (fr) * | 1985-07-04 | 1989-03-17 | Ire Celltarg Sa | Anticorps utiles comme agents de pilotage et conjugues les incorporant |
| GB8607679D0 (en) * | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| IL162181A (en) * | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| IL115770A (en) * | 1989-04-14 | 1999-03-12 | American Cyanamid Co | Substituted disulfides of formula q-sp-ss-w their preparation and use for inhibiting the growth of tumours and for treating bacterial infections |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
-
1991
- 1991-09-26 GB GB919120467A patent/GB9120467D0/en active Pending
-
1992
- 1992-09-24 WO PCT/GB1992/001759 patent/WO1993006231A1/en not_active Ceased
- 1992-09-24 DE DE69232991T patent/DE69232991T2/de not_active Expired - Lifetime
- 1992-09-24 AU AU25983/92A patent/AU666868B2/en not_active Expired
- 1992-09-24 JP JP50593493A patent/JP3498957B2/ja not_active Expired - Lifetime
- 1992-09-24 DK DK97200482T patent/DK0781845T3/da active
- 1992-09-24 AT AT97200482T patent/ATE236251T1/de not_active IP Right Cessation
- 1992-09-24 ES ES92308680T patent/ES2108732T3/es not_active Expired - Lifetime
- 1992-09-24 EP EP97200482A patent/EP0781845B1/de not_active Expired - Lifetime
- 1992-09-24 AT AT92308680T patent/ATE160362T1/de not_active IP Right Cessation
- 1992-09-24 EP EP92308680A patent/EP0534742B1/de not_active Expired - Lifetime
- 1992-09-24 DE DE69223206T patent/DE69223206T2/de not_active Expired - Lifetime
- 1992-09-24 IL IL103269A patent/IL103269A/en not_active IP Right Cessation
- 1992-09-24 CA CA002095926A patent/CA2095926C/en not_active Expired - Lifetime
- 1992-09-24 NZ NZ244468A patent/NZ244468A/en unknown
-
1995
- 1995-05-25 US US08/450,809 patent/US6506881B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9120467D0 (en) | 1991-11-06 |
| JPH06505399A (ja) | 1994-06-23 |
| WO1993006231A1 (en) | 1993-04-01 |
| CA2095926A1 (en) | 1993-03-27 |
| AU666868B2 (en) | 1996-02-29 |
| EP0781845B1 (de) | 2003-04-02 |
| US6506881B1 (en) | 2003-01-14 |
| IL103269A (en) | 1998-01-04 |
| DE69232991D1 (de) | 2003-05-08 |
| IL103269A0 (en) | 1993-02-21 |
| AU2598392A (en) | 1993-04-27 |
| JP3498957B2 (ja) | 2004-02-23 |
| NZ244468A (en) | 1994-11-25 |
| DE69223206T2 (de) | 1998-06-25 |
| ATE160362T1 (de) | 1997-12-15 |
| DE69223206D1 (de) | 1998-01-02 |
| EP0781845A2 (de) | 1997-07-02 |
| DE69232991T2 (de) | 2004-01-15 |
| EP0534742A1 (de) | 1993-03-31 |
| EP0781845A3 (de) | 1997-07-09 |
| EP0534742B1 (de) | 1997-11-19 |
| DK0781845T3 (da) | 2003-06-16 |
| ES2108732T3 (es) | 1998-01-01 |
| CA2095926C (en) | 2002-07-16 |
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