ATE237618T1 - 7a-substituierte hexahydro-1h- pyrrolizinverbindungen verwendbar zur kontrolle von chemische synaptische übertragung - Google Patents

7a-substituierte hexahydro-1h- pyrrolizinverbindungen verwendbar zur kontrolle von chemische synaptische übertragung

Info

Publication number
ATE237618T1
ATE237618T1 AT98907359T AT98907359T ATE237618T1 AT E237618 T1 ATE237618 T1 AT E237618T1 AT 98907359 T AT98907359 T AT 98907359T AT 98907359 T AT98907359 T AT 98907359T AT E237618 T1 ATE237618 T1 AT E237618T1
Authority
AT
Austria
Prior art keywords
synaptic transmission
compounds usable
controlling chemical
chemical synaptic
substituted hexahydro
Prior art date
Application number
AT98907359T
Other languages
English (en)
Inventor
James T Wasicak
David S Garvey
Mark W Holladay
Nan-Horng Lin
Keith B Ryther
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE237618T1 publication Critical patent/ATE237618T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT98907359T 1997-02-19 1998-02-05 7a-substituierte hexahydro-1h- pyrrolizinverbindungen verwendbar zur kontrolle von chemische synaptische übertragung ATE237618T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/802,978 US5733912A (en) 1997-02-19 1997-02-19 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
PCT/US1998/002032 WO1998037082A1 (en) 1997-02-19 1998-02-05 7a-HETEROCYCLE-SUBSTITUTED HEXAHYDRO-1H-PYRROLIZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION

Publications (1)

Publication Number Publication Date
ATE237618T1 true ATE237618T1 (de) 2003-05-15

Family

ID=25185234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98907359T ATE237618T1 (de) 1997-02-19 1998-02-05 7a-substituierte hexahydro-1h- pyrrolizinverbindungen verwendbar zur kontrolle von chemische synaptische übertragung

Country Status (15)

Country Link
US (1) US5733912A (de)
EP (1) EP0970083B1 (de)
JP (1) JP2001512479A (de)
AR (1) AR011148A1 (de)
AT (1) ATE237618T1 (de)
AU (1) AU6318898A (de)
CA (1) CA2281800A1 (de)
CO (1) CO4920251A1 (de)
DE (1) DE69813536T2 (de)
DK (1) DK0970083T3 (de)
ES (1) ES2196548T3 (de)
PT (1) PT970083E (de)
TW (1) TW513425B (de)
WO (1) WO1998037082A1 (de)
ZA (1) ZA981301B (de)

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PT1519939E (pt) 2002-07-05 2010-02-10 Targacept Inc Compostos n-arildiazaspirocíclicos e métodos para a sua preparação e utilização
JP2008510711A (ja) * 2004-08-20 2008-04-10 ターガセプト，インコーポレイテッド 嗜癖治療におけるｎ−アリールジアザスピラ環状化合物の使用
AU2005287037A1 (en) * 2004-09-20 2006-03-30 Targacept, Inc. Azaspiroalkene and azaspiroalkane compounds with nicotinic cholinergic receptor activity
US9029557B2 (en) 2004-12-07 2015-05-12 The Regents Of The University Of California Labeled A4B2 ligands and methods therefor
US8378109B2 (en) * 2004-12-07 2013-02-19 The Regents Of The University Of California Labeled ALPHA4BETA2 ligands and methods therefor
DE102006050794A1 (de) * 2006-10-27 2008-04-30 Bayer Cropscience Ag Verwendung 7A-substituierter Hexahydro-1H-pyrrolizinverbindungen zur Bekämpfung tierischer Schädlinge
EP2935216B1 (de) 2012-12-17 2018-06-27 Sun Pharmaceutical Industries Limited Verfahren zur herstellung von tofacitinib und zwischenprodukten davon
NZ710740A (en) 2013-02-28 2020-06-26 Dermira Inc Glycopyrrolate salts
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
JP7050165B2 (ja) 2018-02-26 2022-04-07 ギリアード サイエンシーズ， インコーポレイテッド Ｈｂｖ複製阻害剤としての置換ピロリジン化合物

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Also Published As

Publication number Publication date
AR011148A1 (es) 2000-08-02
PT970083E (pt) 2003-09-30
DK0970083T3 (da) 2003-08-11
JP2001512479A (ja) 2001-08-21
ZA981301B (en) 1998-08-28
EP0970083B1 (de) 2003-04-16
EP0970083A1 (de) 2000-01-12
DE69813536D1 (de) 2003-05-22
CA2281800A1 (en) 1998-08-27
WO1998037082A1 (en) 1998-08-27
DE69813536T2 (de) 2004-02-19
US5733912A (en) 1998-03-31
TW513425B (en) 2002-12-11
CO4920251A1 (es) 2000-05-29
AU6318898A (en) 1998-09-09
HK1026416A1 (en) 2000-12-15
ES2196548T3 (es) 2003-12-16

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