DK0970083T3 - 7a-heterocykylsubstituerede hexahydro-1H-pyrolizin-forbindelser, der er nyttige til styring af kemisk synaptisk transmission - Google Patents

7a-heterocykylsubstituerede hexahydro-1H-pyrolizin-forbindelser, der er nyttige til styring af kemisk synaptisk transmission

Info

Publication number
DK0970083T3
DK0970083T3 DK98907359T DK98907359T DK0970083T3 DK 0970083 T3 DK0970083 T3 DK 0970083T3 DK 98907359 T DK98907359 T DK 98907359T DK 98907359 T DK98907359 T DK 98907359T DK 0970083 T3 DK0970083 T3 DK 0970083T3
Authority
DK
Denmark
Prior art keywords
pyrolizine
heterocycle
compounds useful
synaptic transmission
controlling chemical
Prior art date
Application number
DK98907359T
Other languages
English (en)
Inventor
James T Wasicak
David S Garvey
Mark W Holladay
Keith B Ryther
Nan-Horng Lin
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0970083T3 publication Critical patent/DK0970083T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK98907359T 1997-02-19 1998-02-05 7a-heterocykylsubstituerede hexahydro-1H-pyrolizin-forbindelser, der er nyttige til styring af kemisk synaptisk transmission DK0970083T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/802,978 US5733912A (en) 1997-02-19 1997-02-19 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
PCT/US1998/002032 WO1998037082A1 (en) 1997-02-19 1998-02-05 7a-HETEROCYCLE-SUBSTITUTED HEXAHYDRO-1H-PYRROLIZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION

Publications (1)

Publication Number Publication Date
DK0970083T3 true DK0970083T3 (da) 2003-08-11

Family

ID=25185234

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98907359T DK0970083T3 (da) 1997-02-19 1998-02-05 7a-heterocykylsubstituerede hexahydro-1H-pyrolizin-forbindelser, der er nyttige til styring af kemisk synaptisk transmission

Country Status (15)

Country Link
US (1) US5733912A (da)
EP (1) EP0970083B1 (da)
JP (1) JP2001512479A (da)
AR (1) AR011148A1 (da)
AT (1) ATE237618T1 (da)
AU (1) AU6318898A (da)
CA (1) CA2281800A1 (da)
CO (1) CO4920251A1 (da)
DE (1) DE69813536T2 (da)
DK (1) DK0970083T3 (da)
ES (1) ES2196548T3 (da)
PT (1) PT970083E (da)
TW (1) TW513425B (da)
WO (1) WO1998037082A1 (da)
ZA (1) ZA981301B (da)

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MY145722A (en) 2000-04-27 2012-03-30 Abbott Lab Diazabicyclic central nervous system active agents
US20030162770A1 (en) 2002-02-22 2003-08-28 Davis Bonnie M. Use of modulators of nicotinic receptors for treatment of cognitive dysfunction
US7432009B2 (en) * 2002-04-03 2008-10-07 3M Innovative Properties Company Lamination apparatus and methods
DK1519939T5 (da) 2002-07-05 2011-01-24 Targacept Inc N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf
JP2008510711A (ja) * 2004-08-20 2008-04-10 ターガセプト，インコーポレイテッド 嗜癖治療におけるｎ−アリールジアザスピラ環状化合物の使用
CN101044134A (zh) * 2004-09-20 2007-09-26 塔加西普特公司 具有烟碱性胆碱能受体活性的氮杂螺烯和氮杂螺烷化合物
US8378109B2 (en) * 2004-12-07 2013-02-19 The Regents Of The University Of California Labeled ALPHA4BETA2 ligands and methods therefor
US9029557B2 (en) 2004-12-07 2015-05-12 The Regents Of The University Of California Labeled A4B2 ligands and methods therefor
DE102006050794A1 (de) * 2006-10-27 2008-04-30 Bayer Cropscience Ag Verwendung 7A-substituierter Hexahydro-1H-pyrrolizinverbindungen zur Bekämpfung tierischer Schädlinge
WO2014097150A1 (en) 2012-12-17 2014-06-26 Ranbaxy Laboratories Limited Process for the preparation of tofacitinib and intermediates thereof
JP6114841B2 (ja) 2013-02-28 2017-04-12 ダーミラ， インク．Ｄｅｒｍｉｒａ， Ｉｎｃ． グリコピロレート塩
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
JP7050165B2 (ja) 2018-02-26 2022-04-07 ギリアード サイエンシーズ， インコーポレイテッド Ｈｂｖ複製阻害剤としての置換ピロリジン化合物

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Also Published As

Publication number Publication date
WO1998037082A1 (en) 1998-08-27
CA2281800A1 (en) 1998-08-27
EP0970083A1 (en) 2000-01-12
TW513425B (en) 2002-12-11
AU6318898A (en) 1998-09-09
ATE237618T1 (de) 2003-05-15
AR011148A1 (es) 2000-08-02
HK1026416A1 (en) 2000-12-15
CO4920251A1 (es) 2000-05-29
ES2196548T3 (es) 2003-12-16
PT970083E (pt) 2003-09-30
US5733912A (en) 1998-03-31
DE69813536T2 (de) 2004-02-19
DE69813536D1 (de) 2003-05-22
EP0970083B1 (en) 2003-04-16
ZA981301B (en) 1998-08-28
JP2001512479A (ja) 2001-08-21

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