ATE238291T1 - Benzopyran-derivate - Google Patents

Benzopyran-derivate

Info

Publication number: ATE238291T1
Authority: AT; Austria
Prior art keywords: polyfluoroalkoxy; alkyl; benzopyran derivatives; cf3so2o; conh2
Prior art date: 1999-10-18

Application number

AT00975868T

Other languages

English (en)

Inventor

Amedeo Leonardi

Gianni Motta

Carlo Riva

Giorgio Sironi

Original Assignee

Recordati Chem Pharm

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-18

Filing date

2000-10-16

Publication date

2003-05-15

2000-10-16 Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238291T1 publication Critical patent/ATE238291T1/de

Links

150000001562 benzopyrans Chemical class 0.000 title abstract 3
230000000694 effects Effects 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
239000000674 adrenergic antagonist Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000004466 alkoxycarbonylamino group Chemical group 0.000 abstract 1
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
102000030619 alpha-1 Adrenergic Receptor Human genes 0.000 abstract 1
108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
230000000414 obstructive effect Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
210000001635 urinary tract Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Saccharide Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

AT00975868T 1999-10-18 2000-10-16 Benzopyran-derivate ATE238291T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1999MI002174A IT1314192B1 (it)	1999-10-18	1999-10-18	Derivati benzopiranici
PCT/EP2000/010143 WO2001029022A1 (en)	1999-10-18	2000-10-16	Benzopyran derivatives

Publications (1)

Publication Number	Publication Date
ATE238291T1 true ATE238291T1 (de)	2003-05-15

Family

ID=11383798

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00975868T ATE238291T1 (de)	1999-10-18	2000-10-16	Benzopyran-derivate

Country Status (10)

Country	Link
EP (1)	EP1222183B1 (de)
JP (1)	JP2003512366A (de)
AT (1)	ATE238291T1 (de)
AU (1)	AU1384701A (de)
DE (1)	DE60002357T2 (de)
DK (1)	DK1222183T3 (de)
ES (1)	ES2197123T3 (de)
IT (1)	IT1314192B1 (de)
PT (1)	PT1222183E (de)
WO (1)	WO2001029022A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR0212824A (pt) *	2001-09-27	2004-10-13	Pharmacia Ab	Composição farmacêutica

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP930210A2 (en) *	1992-02-25	1995-06-30	Recordati Chem Pharm	Heterobicyclic compounds and pharmaceutical preparations containing them
AU9256498A (en) *	1997-08-01	1999-02-22	Recordati S.A. Chemical And Pharmaceutical Company	1,4-disubstituted piperazines
IT1293807B1 (it) *	1997-08-01	1999-03-10	Recordati Chem Pharm	Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico

1999
- 1999-10-18 IT IT1999MI002174A patent/IT1314192B1/it active
2000
- 2000-10-16 PT PT00975868T patent/PT1222183E/pt unknown
- 2000-10-16 AU AU13847/01A patent/AU1384701A/en not_active Abandoned
- 2000-10-16 EP EP00975868A patent/EP1222183B1/de not_active Expired - Lifetime
- 2000-10-16 WO PCT/EP2000/010143 patent/WO2001029022A1/en not_active Ceased
- 2000-10-16 AT AT00975868T patent/ATE238291T1/de not_active IP Right Cessation
- 2000-10-16 DE DE60002357T patent/DE60002357T2/de not_active Expired - Fee Related
- 2000-10-16 DK DK00975868T patent/DK1222183T3/da active
- 2000-10-16 JP JP2001531822A patent/JP2003512366A/ja active Pending
- 2000-10-16 ES ES00975868T patent/ES2197123T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU1384701A (en)	2001-04-30
JP2003512366A (ja)	2003-04-02
EP1222183A1 (de)	2002-07-17
ITMI992174A1 (it)	2001-04-18
WO2001029022A1 (en)	2001-04-26
DE60002357D1 (de)	2003-05-28
ES2197123T3 (es)	2004-01-01
IT1314192B1 (it)	2002-12-06
PT1222183E (pt)	2003-08-29
EP1222183B1 (de)	2003-04-23
ITMI992174A0 (it)	1999-10-18
DK1222183T3 (da)	2003-08-11
DE60002357T2 (de)	2004-02-12

Legal Events

Date

Code

Title

Description

2003-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1222183

Country of ref document: EP

2005-07-15

REN

Ceased due to non-payment of the annual fee

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