ATE238331T1 - Neue hydroxyderivate von tylosin und verfahren zu deren herstellung - Google Patents

Neue hydroxyderivate von tylosin und verfahren zu deren herstellung

Info

Publication number: ATE238331T1
Authority: AT; Austria
Prior art keywords: tylosine; production; hydroxy derivatives; new hydroxy; present
Prior art date: 1998-09-10

Application number

AT99117654T

Other languages

English (en)

Inventor

Amalija Narandja

Nevenka Lopotar

Zoran Mandic

Original Assignee

Pliva Pharm & Chem Works

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-10

Filing date

1999-09-07

Publication date

2003-05-15

1999-09-07 Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE238331T1 publication Critical patent/ATE238331T1/de

Links

238000000034 method Methods 0.000 title abstract 2
-1 HYDROXY DERIVATIVES OF TYLOSINE Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
230000003197 catalytic effect Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
238000006146 oximation reaction Methods 0.000 abstract 1
WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Seasonings (AREA)
Steroid Compounds (AREA)

AT99117654T 1998-09-10 1999-09-07 Neue hydroxyderivate von tylosin und verfahren zu deren herstellung ATE238331T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HR980496A HRP980496B1 (en)	1998-09-10	1998-09-10	New thilozine hydroxy derivatives and a process for the preparation thereof

Publications (1)

Publication Number	Publication Date
ATE238331T1 true ATE238331T1 (de)	2003-05-15

Family

ID=10946806

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99117654T ATE238331T1 (de)	1998-09-10	1999-09-07	Neue hydroxyderivate von tylosin und verfahren zu deren herstellung

Country Status (19)

Country	Link
US (1)	US6211348B1 (de)
EP (1)	EP0985679B8 (de)
JP (1)	JP2000086691A (de)
CN (1)	CN1150202C (de)
AT (1)	ATE238331T1 (de)
BG (1)	BG64561B1 (de)
CA (1)	CA2281496C (de)
CZ (1)	CZ294935B6 (de)
DE (1)	DE69907101T2 (de)
DK (1)	DK0985679T3 (de)
ES (1)	ES2198102T3 (de)
HR (1)	HRP980496B1 (de)
HU (1)	HUP9903063A2 (de)
NO (1)	NO312839B1 (de)
PL (1)	PL195483B1 (de)
RU (1)	RU2220149C2 (de)
SI (1)	SI0985679T1 (de)
SK (1)	SK284841B6 (de)
UA (1)	UA66355C2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7247617B2 (en)	2004-07-13	2007-07-24	Kosan Biosciences Incorporated	Sixteen-member macrolide antiinfective agents
WO2006073172A1 (ja) *	2005-01-07	2006-07-13	Meiji Seika Kaisha, Ltd.	12-オキシ-13-アミノ含有16員環マクロライド誘導体及びその製造法
FR2891835B1 (fr) *	2005-10-11	2007-12-14	Alchimer Sa	Procede de modification de surfaces de polymeres, notamment d'hydroxylation de surfaces de polymeres, et produits tels qu'obtenus
CN117510561B (zh) *	2023-11-30	2024-04-02	中国农业科学院饲料研究所	一种泰乐菌素衍生物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BG32649A1 (en) *	1981-03-26	1982-09-15	Kirov	Method for obtaining of antibiotic tilozine
AU551142B2 (en) *	1981-07-09	1986-04-17	Zaidan Hojin Biseibutsu Kagaku Kenkyukai	Tylosin derivatives
US4454314A (en) *	1982-08-02	1984-06-12	Pfizer Inc.	Antibacterial mycaminosyl tylonolide and related macrolide derivatives
EP0265735B1 (de) *	1986-10-22	1991-01-16	Ferag AG	Verfahren und Vorrichtung zum Übernehmen von gefalzten Druckereierzeugnissen von Druckmaschinen
SI8710674B (sl) *	1987-04-14	1998-06-30	Pliva	Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina
DE4200145A1 (de) *	1992-01-07	1993-07-08	Kali Chemie Pharma Gmbh	7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP3063943B2 (ja) *	1992-02-26	2000-07-12	明治製菓株式会社	血漿中において抗菌活性の持続する新規１６員環マクロリド誘導体及びその合成中間体とそれらの製造法
HRP950449A2 (en) *	1995-08-14	1997-12-31	Nevenka Lopotar	Derivatives of 12, 13-epoxy-tylosin and processes of manufacture thereof
HRP960509A2 (en) *	1996-10-30	1998-06-30	Pliva Pharm & Chem Works	Novel polyhydro tylosin derivatives and a process for the preparation thereof

1998
- 1998-09-10 HR HR980496A patent/HRP980496B1/xx not_active IP Right Cessation
1999
- 1999-09-06 CZ CZ19993154A patent/CZ294935B6/cs not_active IP Right Cessation
- 1999-09-07 DK DK99117654T patent/DK0985679T3/da active
- 1999-09-07 SI SI9930319T patent/SI0985679T1/xx unknown
- 1999-09-07 AT AT99117654T patent/ATE238331T1/de not_active IP Right Cessation
- 1999-09-07 ES ES99117654T patent/ES2198102T3/es not_active Expired - Lifetime
- 1999-09-07 DE DE69907101T patent/DE69907101T2/de not_active Expired - Lifetime
- 1999-09-07 EP EP99117654A patent/EP0985679B8/de not_active Expired - Lifetime
- 1999-09-09 NO NO19994366A patent/NO312839B1/no unknown
- 1999-09-09 RU RU99119585/04A patent/RU2220149C2/ru not_active IP Right Cessation
- 1999-09-09 UA UA99095030A patent/UA66355C2/uk unknown
- 1999-09-09 CA CA002281496A patent/CA2281496C/en not_active Expired - Fee Related
- 1999-09-10 US US09/393,322 patent/US6211348B1/en not_active Expired - Fee Related
- 1999-09-10 CN CNB991220617A patent/CN1150202C/zh not_active Expired - Fee Related
- 1999-09-10 HU HU9903063A patent/HUP9903063A2/hu unknown
- 1999-09-10 BG BG103726A patent/BG64561B1/bg unknown
- 1999-09-10 JP JP11256906A patent/JP2000086691A/ja active Pending
- 1999-09-10 SK SK1241-99A patent/SK284841B6/sk unknown
- 1999-09-10 PL PL335362A patent/PL195483B1/pl unknown

Also Published As

Publication number	Publication date
UA66355C2 (en)	2004-05-17
DE69907101T2 (de)	2004-04-08
HRP980496A2 (en)	2000-04-30
HRP980496B1 (en)	2007-03-31
RU2220149C2 (ru)	2003-12-27
HUP9903063A2 (hu)	2000-03-28
DK0985679T3 (da)	2003-08-11
NO994366L (no)	2000-03-13
CN1150202C (zh)	2004-05-19
CN1250054A (zh)	2000-04-12
JP2000086691A (ja)	2000-03-28
NO312839B1 (no)	2002-07-08
DE69907101D1 (de)	2003-05-28
CZ294935B6 (cs)	2005-04-13
CZ315499A3 (cs)	2000-04-12
NO994366D0 (no)	1999-09-09
CA2281496A1 (en)	2000-03-10
SI0985679T1 (en)	2003-10-31
EP0985679B8 (de)	2003-09-03
ES2198102T3 (es)	2004-01-16
EP0985679A1 (de)	2000-03-15
BG103726A (en)	2000-12-29
PL335362A1 (en)	2000-03-13
EP0985679B1 (de)	2003-04-23
BG64561B1 (bg)	2005-07-29
US6211348B1 (en)	2001-04-03
CA2281496C (en)	2005-11-01
SK124199A3 (en)	2000-12-11
SK284841B6 (sk)	2005-12-01
PL195483B1 (pl)	2007-09-28

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2004-03-15

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2009-06-15

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