ATE239485T1 - Ophthalmische pharmazeutische zubereitung die n- acetylcystein und polyvinylalkohol enthält - Google Patents
Ophthalmische pharmazeutische zubereitung die n- acetylcystein und polyvinylalkohol enthältInfo
- Publication number
- ATE239485T1 ATE239485T1 AT93100278T AT93100278T ATE239485T1 AT E239485 T1 ATE239485 T1 AT E239485T1 AT 93100278 T AT93100278 T AT 93100278T AT 93100278 T AT93100278 T AT 93100278T AT E239485 T1 ATE239485 T1 AT E239485T1
- Authority
- AT
- Austria
- Prior art keywords
- acetylcysteine
- polyvinyl alcohol
- pharmaceutical preparation
- ophthalmic pharmaceutical
- preparation containing
- Prior art date
Links
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title abstract 2
- 239000004372 Polyvinyl alcohol Substances 0.000 title abstract 2
- 229960004308 acetylcysteine Drugs 0.000 title abstract 2
- 229920002451 polyvinyl alcohol Polymers 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 abstract 1
- 206010013774 Dry eye Diseases 0.000 abstract 1
- 208000009319 Keratoconjunctivitis Sicca Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920074A IT1258781B (it) | 1992-01-16 | 1992-01-16 | Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239485T1 true ATE239485T1 (de) | 2003-05-15 |
Family
ID=11361572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93100278T ATE239485T1 (de) | 1992-01-16 | 1993-01-11 | Ophthalmische pharmazeutische zubereitung die n- acetylcystein und polyvinylalkohol enthält |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5510101A (de) |
| EP (1) | EP0551848B1 (de) |
| JP (1) | JP3443128B2 (de) |
| AT (1) | ATE239485T1 (de) |
| AU (1) | AU653091B2 (de) |
| CA (1) | CA2087420C (de) |
| DE (1) | DE69332939T2 (de) |
| ES (1) | ES2197146T3 (de) |
| IT (1) | IT1258781B (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2350715A1 (en) * | 1999-08-09 | 2001-04-12 | Webb-Waring Institute For Biomedical Research | A method for the treatment of ocular oxidative stress |
| US7022315B2 (en) * | 2000-04-26 | 2006-04-04 | Oregon Health & Science University | Administration of a thiol-based chemoprotectant compound |
| EP1609468A3 (de) * | 2000-11-22 | 2006-01-25 | Rxkinetix, Inc. | Eine Zusammensetzung auf der Basis eines Schwefel enthaltenden Antioxidans wie dessen Verwendung zur Herstellung eines Medikaments für die Behandlung von Mucositis |
| FR2819186A1 (fr) * | 2001-01-10 | 2002-07-12 | L M D | Cystine-voie orale-syndrome de l'oeil sec |
| ITRM20010438A1 (it) * | 2001-07-23 | 2003-01-23 | Farmigea Spa | Preparato oftalmico a base di n-acetilcisteina per il trattamento della sindrome dell'occhio secco. |
| GB0123115D0 (en) * | 2001-09-26 | 2001-11-14 | Pharma Sol Int Ltd | Saline solutions for clinical use |
| US20050118261A1 (en) * | 2003-06-12 | 2005-06-02 | Oien Hal J. | Compositions and methods of administering doxepin to mucosal tissue |
| US20070077303A1 (en) * | 2005-09-30 | 2007-04-05 | Azaam Alli | Methods for providing oxidatively stable ophthalmic compositions |
| CA2635603C (en) * | 2005-11-30 | 2016-01-19 | Endo Pharmaceuticals Inc. | Treatment of xerostomia |
| SG10202003901UA (en) | 2005-12-13 | 2020-05-28 | Incyte Holdings Corp | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors |
| KR20150036210A (ko) | 2007-06-13 | 2015-04-07 | 인사이트 코포레이션 | 야누스 키나제 억제제(R)―3―(4―(7H―피롤로[2,3-d]피리미딘―4―일)―1H―피라졸―1―일)―3―사이클로펜틸프로판니트릴의 염 |
| CL2009001884A1 (es) * | 2008-10-02 | 2010-05-14 | Incyte Holdings Corp | Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco. |
| AR076794A1 (es) | 2009-05-22 | 2011-07-06 | Incyte Corp | Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen |
| SI2432472T1 (sl) * | 2009-05-22 | 2019-11-29 | Incyte Holdings Corp | 3-(4-(7H-pirolo(2,3-d)pirimidin-4-il)-1H-pirazol-1-il)oktan- ali heptan-nitril kot inhibitorji JAK |
| TW201113285A (en) * | 2009-09-01 | 2011-04-16 | Incyte Corp | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| EP3354652B1 (de) | 2010-03-10 | 2020-05-06 | Incyte Holdings Corporation | Piperidin-4-yl azetidin-derivate als jak1-inhibitoren |
| PE20130216A1 (es) | 2010-05-21 | 2013-02-27 | Incyte Corp | Formulacion topica para un inhibidor de jak |
| PE20140146A1 (es) | 2010-11-19 | 2014-02-06 | Incyte Corp | Derivados de pirrolopiridina y pirrolopirimidina sustituidos con ciclobutilo como inhibidores de jak |
| US9034884B2 (en) | 2010-11-19 | 2015-05-19 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors |
| CN103797010B (zh) | 2011-06-20 | 2016-02-24 | 因塞特控股公司 | 作为jak抑制剂的氮杂环丁烷基苯基、吡啶基或吡嗪基甲酰胺衍生物 |
| TW201313721A (zh) | 2011-08-18 | 2013-04-01 | Incyte Corp | 作為jak抑制劑之環己基氮雜環丁烷衍生物 |
| UA111854C2 (uk) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | Способи і проміжні сполуки для отримання інгібіторів jak |
| TW201406761A (zh) | 2012-05-18 | 2014-02-16 | Incyte Corp | 做爲jak抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物 |
| PH12020551186B1 (en) | 2012-11-15 | 2024-03-20 | Incyte Holdings Corp | Sustained-release dosage forms of ruxolitinib |
| RS62867B1 (sr) | 2013-03-06 | 2022-02-28 | Incyte Holdings Corp | Postupci i intermedijeri za dobijanje inhibitora jak |
| SMT202000315T1 (it) | 2013-08-07 | 2020-07-08 | Incyte Corp | Forme di dosaggio a rilascio prolungato per un inibitore di jak1 |
| EP3139903B1 (de) | 2014-05-07 | 2019-07-03 | Croma-Pharma Gesellschaft m.b.H. | Wässrige opthalmische lösung und verfahren zur behandlung von trockenem augensyndrom |
| US9498467B2 (en) | 2014-05-30 | 2016-11-22 | Incyte Corporation | Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1 |
| KR20180066240A (ko) | 2015-10-30 | 2018-06-18 | 크로마-파르마 게젤샤프트 엠.베.하. | 무균 수성 안과용 액제의 치료적 용도 |
| RU2741912C2 (ru) | 2015-10-30 | 2021-01-29 | Крома-Фарма Гезелльшафт М.Б.Х. | Применение в терапии стерильного водного офтальмологического раствора |
| EP3600272A4 (de) * | 2017-03-29 | 2021-01-13 | Azura Ophthalmics Ltd. | Mittel zur erhöhung der lipidsekretion der meibomdrüse |
| WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| SG11202007164UA (en) | 2018-01-30 | 2020-08-28 | Incyte Corp | Processes for preparing (1 -(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one) |
| SMT202400306T1 (it) | 2018-03-30 | 2024-09-16 | Incyte Corp | Trattamento dell'idrosadenite suppurativa utilizzando inibitori di jak. |
| US20220409526A1 (en) * | 2019-11-08 | 2022-12-29 | Retina Foundation Of The Southwest | Compounds and implants for treating ocular disorders |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4120949A (en) * | 1977-10-05 | 1978-10-17 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4131651A (en) * | 1977-10-25 | 1978-12-26 | Barnes-Hind Pharmaceuticals, Inc. | Treatment of dry eye |
| US4409205A (en) * | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| BE901885A (fr) * | 1985-03-06 | 1985-07-01 | Bruschettini Srl | Composition pharmaceutique sous forme de lotion ophtalmique et son procede de preparation. |
| US4883658A (en) * | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
| IT1249047B (it) * | 1991-02-21 | 1995-02-11 | Zambon Spa | Composizione farmaceutica per il trattamento della cataratta |
| NZ242358A (en) * | 1991-05-10 | 1994-03-25 | Allergan Inc | Use of thiol compounds to inhibit deposits on a contact lens |
-
1992
- 1992-01-16 IT ITMI920074A patent/IT1258781B/it active IP Right Grant
-
1993
- 1993-01-11 EP EP93100278A patent/EP0551848B1/de not_active Expired - Lifetime
- 1993-01-11 AU AU31136/93A patent/AU653091B2/en not_active Ceased
- 1993-01-11 ES ES93100278T patent/ES2197146T3/es not_active Expired - Lifetime
- 1993-01-11 AT AT93100278T patent/ATE239485T1/de not_active IP Right Cessation
- 1993-01-11 DE DE69332939T patent/DE69332939T2/de not_active Expired - Fee Related
- 1993-01-15 CA CA002087420A patent/CA2087420C/en not_active Expired - Fee Related
- 1993-01-18 JP JP00615293A patent/JP3443128B2/ja not_active Expired - Fee Related
-
1994
- 1994-03-17 US US08/214,232 patent/US5510101A/en not_active Expired - Fee Related
- 1994-06-03 US US08/253,587 patent/US5488069A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU653091B2 (en) | 1994-09-15 |
| ITMI920074A0 (it) | 1992-01-16 |
| ES2197146T3 (es) | 2004-01-01 |
| DE69332939T2 (de) | 2004-04-01 |
| CA2087420C (en) | 2004-04-20 |
| CA2087420A1 (en) | 1993-07-17 |
| US5510101A (en) | 1996-04-23 |
| AU3113693A (en) | 1993-07-22 |
| ITMI920074A1 (it) | 1993-07-16 |
| JP3443128B2 (ja) | 2003-09-02 |
| EP0551848B1 (de) | 2003-05-07 |
| JPH069383A (ja) | 1994-01-18 |
| US5488069A (en) | 1996-01-30 |
| EP0551848A1 (de) | 1993-07-21 |
| DE69332939D1 (de) | 2003-06-12 |
| IT1258781B (it) | 1996-02-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE239485T1 (de) | Ophthalmische pharmazeutische zubereitung die n- acetylcystein und polyvinylalkohol enthält | |
| RU94040170A (ru) | Изохинолины | |
| AU659444B2 (en) | Intermediates for the manufacture of 6-fluoro-1, 4-dihydro-4-oxoquinoline carboxylic acids | |
| DK153687A (da) | Laegemiddel-adsorbater og deres fremstilling | |
| OA09123A (fr) | Composition pharmaceutique pour la prévention des maladies sexuellement transmissibles. | |
| RU94041223A (ru) | Средство для лечения мотонейроновых заболеваний | |
| ES2057124T3 (es) | Producto terapeutico para el tratamiento de estados peri- o post-menopausicos. | |
| NO890259L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive etylfenoksyacetamider. | |
| DE69326539D1 (de) | Zytotoxische arzneimittel therapie | |
| RU93045145A (ru) | Замещенные производные циклогексана и их применение для лечения заболеваний, содержащее их лекарственное средство | |
| EP0235589A3 (en) | Use of quinolone and naphthyridine antibiotics for the manufacture of ophthalmic medicaments | |
| IT1231107B (it) | Procedimento e dispositivo per la fabbricazione di lattine mediante stiramento. | |
| FI945000A0 (fi) | Menetelmä (S)-amino-1-substituoitujen pyrrolidiinien valmistamiseksi | |
| NO175307C (no) | Analogifremgangsmåte for fremstilling av nye terapeutisk aktive 3,3'-ditiobis(propionsyrer) | |
| NZ250300A (en) | Asymmetric pyrrolidine derivatives | |
| AU3709289A (en) | Strontium salt | |
| IT9020968A0 (it) | Metodi e composizioni farmaceutiche per il trattamento di malattie oftalmiche | |
| ATE172114T1 (de) | Pharmazeutische zusammensetzung, die carbachol und andere cholinerge substanzen enthält | |
| NO881884L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive pyrrolidin-derivater. | |
| ITMI922296A0 (it) | Procedimento per la preparazione di antibiotici beta-lattamici sterili | |
| IL89401A0 (en) | Medicaments containing 1,4-dihydropyridine derivatives for the treatment of alcohol addiction | |
| BR9302809A (pt) | Composto,processo para sua preparacao,processo de purificacao dos compostos,medicmanto,emprego e processo para a preparacao de um agente anti-tumoral | |
| AU7379587A (en) | Pharmaceutical formulation for the treatment of bacterial infections | |
| AU6600190A (en) | Therapeutic compositions; methods for treatment of hiv infections | |
| AU2776389A (en) | Beta-lactam antibiotics, processes for their preparation and their use as and in medicaments |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0551848 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |