ATE242242T1 - Derivate von imidazo(1,2-a)pyridin zur behandlung von gastrointestinalen krankheiten - Google Patents

Derivate von imidazo(1,2-a)pyridin zur behandlung von gastrointestinalen krankheiten

Info

Publication number
ATE242242T1
ATE242242T1 AT99944965T AT99944965T ATE242242T1 AT E242242 T1 ATE242242 T1 AT E242242T1 AT 99944965 T AT99944965 T AT 99944965T AT 99944965 T AT99944965 T AT 99944965T AT E242242 T1 ATE242242 T1 AT E242242T1
Authority
AT
Austria
Prior art keywords
imidazo
pyridine
derivatives
treatment
gastrointestinal diseases
Prior art date
Application number
AT99944965T
Other languages
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE242242T1 publication Critical patent/ATE242242T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99944965T 1998-08-21 1999-08-18 Derivate von imidazo(1,2-a)pyridin zur behandlung von gastrointestinalen krankheiten ATE242242T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802793A SE9802793D0 (sv) 1998-08-21 1998-08-21 New compounds
PCT/SE1999/001401 WO2000010999A2 (en) 1998-08-21 1999-08-18 New compounds

Publications (1)

Publication Number Publication Date
ATE242242T1 true ATE242242T1 (de) 2003-06-15

Family

ID=20412306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99944965T ATE242242T1 (de) 1998-08-21 1999-08-18 Derivate von imidazo(1,2-a)pyridin zur behandlung von gastrointestinalen krankheiten

Country Status (21)

Country Link
US (1) US6613775B1 (de)
EP (1) EP1105390B1 (de)
JP (1) JP2002523414A (de)
KR (1) KR20010072797A (de)
CN (1) CN1161355C (de)
AR (1) AR020225A1 (de)
AT (1) ATE242242T1 (de)
AU (1) AU770511B2 (de)
BR (1) BR9913102A (de)
CA (1) CA2339372A1 (de)
DE (1) DE69908608T2 (de)
DK (1) DK1105390T3 (de)
ES (1) ES2201769T3 (de)
IL (1) IL141165A0 (de)
MY (1) MY121387A (de)
NO (1) NO20010861L (de)
NZ (1) NZ509744A (de)
PT (1) PT1105390E (de)
SE (1) SE9802793D0 (de)
WO (1) WO2000010999A2 (de)
ZA (1) ZA200100911B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005026164A1 (en) * 2003-09-18 2005-03-24 Altana Pharma Ag Pharmacologically active imidazo[4,5-c]pyridines
KR20060099524A (ko) 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-ａ]피리딘유도체
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2575345A1 (en) * 2004-08-02 2006-02-09 Altana Pharma Ag 5-substituted 1h-pyrrolo[3,2-b]pyridines
KR101068355B1 (ko) * 2005-03-09 2011-09-28 주식회사유한양행 신규의 이미다조[1,2-ａ]피리딘 유도체 및 그의 제조방법
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
WO2006100119A1 (en) * 2005-03-24 2006-09-28 Glaxo Group Limited Derivatives of imidazo (1,2-a) pyridine useful as medicaments for treating gastrointestinal diseases
AU2010270797B2 (en) 2009-07-08 2015-03-19 Dermira (Canada), Inc. TOFA analogs useful in treating dermatological disorders or conditions
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers

Also Published As

Publication number Publication date
NO20010861D0 (no) 2001-02-20
HK1036274A1 (en) 2001-12-28
ZA200100911B (en) 2002-05-02
PT1105390E (pt) 2003-10-31
SE9802793D0 (sv) 1998-08-21
IL141165A0 (en) 2002-11-10
JP2002523414A (ja) 2002-07-30
ES2201769T3 (es) 2004-03-16
BR9913102A (pt) 2001-05-08
DE69908608T2 (de) 2004-04-29
WO2000010999A2 (en) 2000-03-02
CN1161355C (zh) 2004-08-11
WO2000010999A3 (en) 2000-06-02
EP1105390A2 (de) 2001-06-13
NO20010861L (no) 2001-04-10
US6613775B1 (en) 2003-09-02
AU5767899A (en) 2000-03-14
CA2339372A1 (en) 2000-03-02
KR20010072797A (ko) 2001-07-31
NZ509744A (en) 2003-05-30
MY121387A (en) 2006-01-28
EP1105390B1 (de) 2003-06-04
DK1105390T3 (da) 2003-09-22
CN1323308A (zh) 2001-11-21
DE69908608D1 (de) 2003-07-10
AR020225A1 (es) 2002-05-02
AU770511B2 (en) 2004-02-26

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