ATE249424T1 - Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen - Google Patents

Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen

Info

Publication number
ATE249424T1
ATE249424T1 AT98954537T AT98954537T ATE249424T1 AT E249424 T1 ATE249424 T1 AT E249424T1 AT 98954537 T AT98954537 T AT 98954537T AT 98954537 T AT98954537 T AT 98954537T AT E249424 T1 ATE249424 T1 AT E249424T1
Authority
AT
Austria
Prior art keywords
bromomethyl
biphenyl compounds
producing derivatives
formula
biphenyl
Prior art date
Application number
AT98954537T
Other languages
English (en)
Inventor
Michel Biard
Bertrand Castro
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE249424T1 publication Critical patent/ATE249424T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98954537T 1997-11-17 1998-11-09 Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen ATE249424T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714376A FR2771090B1 (fr) 1997-11-17 1997-11-17 Procede de preparation de derives de bromomethyl-biphenyle
PCT/FR1998/002383 WO1999025681A1 (fr) 1997-11-17 1998-11-09 Procede de preparation de derives de bromomethyl-biphenyle

Publications (1)

Publication Number Publication Date
ATE249424T1 true ATE249424T1 (de) 2003-09-15

Family

ID=9513439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98954537T ATE249424T1 (de) 1997-11-17 1998-11-09 Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen

Country Status (15)

Country Link
US (1) US6214999B1 (de)
EP (1) EP1032557B1 (de)
JP (1) JP4546642B2 (de)
AT (1) ATE249424T1 (de)
AU (1) AU1160899A (de)
BR (1) BR9814651B1 (de)
CA (1) CA2310324C (de)
DE (1) DE69818091T2 (de)
DK (1) DK1032557T5 (de)
ES (1) ES2207004T3 (de)
FR (1) FR2771090B1 (de)
HU (1) HU228640B1 (de)
NO (1) NO327836B1 (de)
PT (1) PT1032557E (de)
WO (1) WO1999025681A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2299616T3 (es) 2002-06-12 2008-06-01 Sumitomo Chemical Company, Limited Procedimiento para producir 4'-bromometil-2-cianobifelino.
US7641181B2 (en) * 2003-01-24 2010-01-05 Liquid Spring Technologies, Inc. Distributed power suspension system
WO2004103947A1 (ja) * 2003-05-20 2004-12-02 Sumitomo Chemical Company, Limited ブロモメチル置換芳香族カルボン酸エステル化合物の製造方法
CN1993355A (zh) * 2004-09-02 2007-07-04 特瓦制药工业有限公司 奥美沙坦酯的纯化方法
US20070054948A1 (en) * 2004-09-02 2007-03-08 Lilach Hedvati Purification of olmesartan medoxomil
WO2006029057A1 (en) * 2004-09-02 2006-03-16 Teva Pharmaceutical Industries, Ltd. Purification of olmesartan medoxomil
KR20080112424A (ko) * 2004-10-15 2008-12-24 테바 파마슈티컬 인더스트리즈 리미티드 텔미사르탄의 제조 방법
EP1716138A1 (de) * 2004-12-30 2006-11-02 Teva Pharmaceutical Industries Ltd Verfahren zur herstellung von olmesartan-medoxomil bei einem ph-wert von über 2,5
CN101094850A (zh) * 2005-01-03 2007-12-26 特瓦制药工业有限公司 具有较低水平杂质的奥美沙坦酯
US20060258727A1 (en) * 2005-01-03 2006-11-16 Lilach Hedvati Olmesartan medoxomil with reduced levels of impurities
WO2008078340A1 (en) * 2006-12-27 2008-07-03 Calyx Chemicals And Pharmaceuticals Ltd. Process for the separation of 4-bromomethyl-2'-substituted biphenyls from 4,4,-dibromomethyl-2'-substituted biphenyls
HUP0900788A2 (en) * 2009-12-16 2011-11-28 Sanofi Aventis Process for producing 4-bromomethyl-biphenyl derivatives
CN105399627A (zh) * 2015-10-22 2016-03-16 威特(湖南)药业有限公司 4’-溴甲基联苯-2-羧酸酯的合成方法
BR112018069438B1 (pt) * 2016-03-31 2022-07-05 Fujifilm Corporation Método para produzir 5- (bromometil) -1-benzotiofeno
CN108164434A (zh) * 2017-12-27 2018-06-15 安徽太主科技发展有限公司 一种低成本4′-溴甲基-2-氰基联苯的制备方法
CN113816874B (zh) * 2021-10-30 2024-01-26 大连双硼医药化工有限公司 一种合成4-氰基-2-氟苄醇的工艺方法
WO2025177293A1 (en) * 2024-02-21 2025-08-28 Council Of Scientific & Industrial Research An autonomous process for selective photo-bromination and nucleophilic substitution of sartan intermediates and their analogues

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806584D0 (en) * 1988-03-19 1988-04-20 Interox Chemicals Ltd Bromination
JPH06298683A (ja) * 1993-04-15 1994-10-25 Sankyo Co Ltd 光反応による4−(2−置換)フェニルベンジルブロミド類の製造法
JPH0859515A (ja) * 1994-08-12 1996-03-05 Sanko Kagaku Kogyo Kk モノブロモメチル化芳香族化合物の製造方法
JP2928982B2 (ja) * 1994-10-27 1999-08-03 住化ファインケム株式会社 4’−ブロモメチル−2−シアノビフェニルの製造法
IT1291551B1 (it) * 1997-04-11 1999-01-11 Luso Farmaco Inst Processo per la preparazione di composti 4-bromometil bifenilici

Also Published As

Publication number Publication date
FR2771090B1 (fr) 2000-02-04
EP1032557A1 (de) 2000-09-06
DE69818091D1 (de) 2003-10-16
NO20002530D0 (no) 2000-05-16
BR9814651A (pt) 2000-10-03
NO327836B1 (no) 2009-10-05
ES2207004T3 (es) 2004-05-16
DK1032557T5 (da) 2004-03-08
HUP0004251A3 (en) 2003-05-28
JP2001523658A (ja) 2001-11-27
HU228640B1 (en) 2013-04-29
CA2310324C (en) 2010-01-26
FR2771090A1 (fr) 1999-05-21
US6214999B1 (en) 2001-04-10
CA2310324A1 (en) 1999-05-27
DK1032557T3 (da) 2004-01-19
BR9814651B1 (pt) 2010-12-14
WO1999025681A1 (fr) 1999-05-27
HUP0004251A2 (hu) 2001-04-28
EP1032557B1 (de) 2003-09-10
NO20002530L (no) 2000-07-17
DE69818091T2 (de) 2004-07-01
AU1160899A (en) 1999-06-07
JP4546642B2 (ja) 2010-09-15
PT1032557E (pt) 2004-02-27

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