DK1032557T3 - Fremgangsmåde til fremstilling af brommethyl-biphenylderivater - Google Patents

Fremgangsmåde til fremstilling af brommethyl-biphenylderivater

Info

Publication number: DK1032557T3
Authority: DK; Denmark
Prior art keywords: bromomethyl; preparation; biphenyl derivatives; formula; biphenyl
Prior art date: 1997-11-17

Application number

DK98954537T

Other languages

English (en)

Other versions

DK1032557T5 (da

Inventor

Michel Biard

Bertrand Castro

Original Assignee

Sanofi Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-17

Filing date

1998-11-09

Publication date

2004-01-19

1998-11-09 Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo

2004-01-19 Application granted granted Critical

2004-01-19 Publication of DK1032557T3 publication Critical patent/DK1032557T3/da

2004-03-08 Publication of DK1032557T5 publication Critical patent/DK1032557T5/da

Links

SEXZHJJUKFXNDY-UHFFFAOYSA-N 1-(bromomethyl)-2-phenylbenzene Chemical group BrCC1=CC=CC=C1C1=CC=CC=C1 SEXZHJJUKFXNDY-UHFFFAOYSA-N 0.000 title 1
HZQLUIZFUXNFHK-UHFFFAOYSA-N 1-(bromomethyl)-4-phenylbenzene Chemical group C1=CC(CBr)=CC=C1C1=CC=CC=C1 HZQLUIZFUXNFHK-UHFFFAOYSA-N 0.000 abstract 1
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
ZZLCFHIKESPLTH-UHFFFAOYSA-N 4-Methylbiphenyl Chemical group C1=CC(C)=CC=C1C1=CC=CC=C1 ZZLCFHIKESPLTH-UHFFFAOYSA-N 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
-1 alkali metal bromate Chemical class 0.000 abstract 1
SXDBWCPKPHAZSM-UHFFFAOYSA-M bromate Inorganic materials [O-]Br(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-M 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK98954537T 1997-11-17 1998-11-09 Fremgangsmåde til fremstilling af brommethyl-biphenylderivater DK1032557T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9714376A FR2771090B1 (fr)	1997-11-17	1997-11-17	Procede de preparation de derives de bromomethyl-biphenyle
PCT/FR1998/002383 WO1999025681A1 (fr)	1997-11-17	1998-11-09	Procede de preparation de derives de bromomethyl-biphenyle

Publications (2)

Publication Number	Publication Date
DK1032557T3 true DK1032557T3 (da)	2004-01-19
DK1032557T5 DK1032557T5 (da)	2004-03-08

Family

ID=9513439

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98954537T DK1032557T5 (da)	1997-11-17	1998-11-09	Fremgangsmåde til fremstilling af brommethyl-biphenylderivater

Country Status (15)

Country	Link
US (1)	US6214999B1 (da)
EP (1)	EP1032557B1 (da)
JP (1)	JP4546642B2 (da)
AT (1)	ATE249424T1 (da)
AU (1)	AU1160899A (da)
BR (1)	BR9814651B1 (da)
CA (1)	CA2310324C (da)
DE (1)	DE69818091T2 (da)
DK (1)	DK1032557T5 (da)
ES (1)	ES2207004T3 (da)
FR (1)	FR2771090B1 (da)
HU (1)	HU228640B1 (da)
NO (1)	NO327836B1 (da)
PT (1)	PT1032557E (da)
WO (1)	WO1999025681A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2299616T3 (es)	2002-06-12	2008-06-01	Sumitomo Chemical Company, Limited	Procedimiento para producir 4'-bromometil-2-cianobifelino.
US7641181B2 (en) *	2003-01-24	2010-01-05	Liquid Spring Technologies, Inc.	Distributed power suspension system
WO2004103947A1 (ja) *	2003-05-20	2004-12-02	Sumitomo Chemical Company, Limited	ブロモメチル置換芳香族カルボン酸エステル化合物の製造方法
CN1993355A (zh) *	2004-09-02	2007-07-04	特瓦制药工业有限公司	奥美沙坦酯的纯化方法
US20070054948A1 (en) *	2004-09-02	2007-03-08	Lilach Hedvati	Purification of olmesartan medoxomil
WO2006029057A1 (en) *	2004-09-02	2006-03-16	Teva Pharmaceutical Industries, Ltd.	Purification of olmesartan medoxomil
KR20080112424A (ko) *	2004-10-15	2008-12-24	테바 파마슈티컬 인더스트리즈 리미티드	텔미사르탄의 제조 방법
EP1716138A1 (en) *	2004-12-30	2006-11-02	Teva Pharmaceutical Industries Ltd	Process for preparing olmesartan medoxomil at ph higher than 2.5
CN101094850A (zh) *	2005-01-03	2007-12-26	特瓦制药工业有限公司	具有较低水平杂质的奥美沙坦酯
US20060258727A1 (en) *	2005-01-03	2006-11-16	Lilach Hedvati	Olmesartan medoxomil with reduced levels of impurities
WO2008078340A1 (en) *	2006-12-27	2008-07-03	Calyx Chemicals And Pharmaceuticals Ltd.	Process for the separation of 4-bromomethyl-2'-substituted biphenyls from 4,4,-dibromomethyl-2'-substituted biphenyls
HUP0900788A2 (en) *	2009-12-16	2011-11-28	Sanofi Aventis	Process for producing 4-bromomethyl-biphenyl derivatives
CN105399627A (zh) *	2015-10-22	2016-03-16	威特(湖南)药业有限公司	4’-溴甲基联苯-2-羧酸酯的合成方法
BR112018069438B1 (pt) *	2016-03-31	2022-07-05	Fujifilm Corporation	Método para produzir 5- (bromometil) -1-benzotiofeno
CN108164434A (zh) *	2017-12-27	2018-06-15	安徽太主科技发展有限公司	一种低成本4′-溴甲基-2-氰基联苯的制备方法
CN113816874B (zh) *	2021-10-30	2024-01-26	大连双硼医药化工有限公司	一种合成4-氰基-2-氟苄醇的工艺方法
WO2025177293A1 (en) *	2024-02-21	2025-08-28	Council Of Scientific & Industrial Research	An autonomous process for selective photo-bromination and nucleophilic substitution of sartan intermediates and their analogues

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8806584D0 (en) *	1988-03-19	1988-04-20	Interox Chemicals Ltd	Bromination
JPH06298683A (ja) *	1993-04-15	1994-10-25	Sankyo Co Ltd	光反応による４−（２−置換）フェニルベンジルブロミド類の製造法
JPH0859515A (ja) *	1994-08-12	1996-03-05	Sanko Kagaku Kogyo Kk	モノブロモメチル化芳香族化合物の製造方法
JP2928982B2 (ja) *	1994-10-27	1999-08-03	住化ファインケム株式会社	４’−ブロモメチル−２−シアノビフェニルの製造法
IT1291551B1 (it) *	1997-04-11	1999-01-11	Luso Farmaco Inst	Processo per la preparazione di composti 4-bromometil bifenilici

1997
- 1997-11-17 FR FR9714376A patent/FR2771090B1/fr not_active Expired - Lifetime
1998
- 1998-11-09 JP JP2000521065A patent/JP4546642B2/ja not_active Expired - Lifetime
- 1998-11-09 BR BRPI9814651-3A patent/BR9814651B1/pt not_active IP Right Cessation
- 1998-11-09 CA CA2310324A patent/CA2310324C/en not_active Expired - Lifetime
- 1998-11-09 AU AU11608/99A patent/AU1160899A/en not_active Abandoned
- 1998-11-09 WO PCT/FR1998/002383 patent/WO1999025681A1/fr not_active Ceased
- 1998-11-09 DK DK98954537T patent/DK1032557T5/da active
- 1998-11-09 HU HU0004251A patent/HU228640B1/hu unknown
- 1998-11-09 ES ES98954537T patent/ES2207004T3/es not_active Expired - Lifetime
- 1998-11-09 PT PT98954537T patent/PT1032557E/pt unknown
- 1998-11-09 DE DE69818091T patent/DE69818091T2/de not_active Expired - Lifetime
- 1998-11-09 EP EP98954537A patent/EP1032557B1/fr not_active Expired - Lifetime
- 1998-11-09 AT AT98954537T patent/ATE249424T1/de active
- 1998-11-09 US US09/554,566 patent/US6214999B1/en not_active Expired - Lifetime
2000
- 2000-05-16 NO NO20002530A patent/NO327836B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2771090B1 (fr)	2000-02-04
ATE249424T1 (de)	2003-09-15
EP1032557A1 (fr)	2000-09-06
DE69818091D1 (de)	2003-10-16
NO20002530D0 (no)	2000-05-16
BR9814651A (pt)	2000-10-03
NO327836B1 (no)	2009-10-05
ES2207004T3 (es)	2004-05-16
DK1032557T5 (da)	2004-03-08
HUP0004251A3 (en)	2003-05-28
JP2001523658A (ja)	2001-11-27
HU228640B1 (en)	2013-04-29
CA2310324C (en)	2010-01-26
FR2771090A1 (fr)	1999-05-21
US6214999B1 (en)	2001-04-10
CA2310324A1 (en)	1999-05-27
BR9814651B1 (pt)	2010-12-14
WO1999025681A1 (fr)	1999-05-27
HUP0004251A2 (hu)	2001-04-28
EP1032557B1 (fr)	2003-09-10
NO20002530L (no)	2000-07-17
DE69818091T2 (de)	2004-07-01
AU1160899A (en)	1999-06-07
JP4546642B2 (ja)	2010-09-15
PT1032557E (pt)	2004-02-27

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