ATE250927T1 - Diltiazem-formulierung mit gesteuerter freigabe - Google Patents

Diltiazem-formulierung mit gesteuerter freigabe

Info

Publication number
ATE250927T1
ATE250927T1 AT96910439T AT96910439T ATE250927T1 AT E250927 T1 ATE250927 T1 AT E250927T1 AT 96910439 T AT96910439 T AT 96910439T AT 96910439 T AT96910439 T AT 96910439T AT E250927 T1 ATE250927 T1 AT E250927T1
Authority
AT
Austria
Prior art keywords
diltiazem
polymeric
layer
coated
controlled release
Prior art date
Application number
AT96910439T
Other languages
English (en)
Inventor
Chih-Ming Chen
Original Assignee
Andrx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andrx Pharmaceuticals Inc filed Critical Andrx Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE250927T1 publication Critical patent/ATE250927T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96910439T 1995-03-24 1996-03-13 Diltiazem-formulierung mit gesteuerter freigabe ATE250927T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/409,449 US5567441A (en) 1995-03-24 1995-03-24 Diltiazem controlled release formulation
PCT/US1996/003399 WO1996029992A1 (en) 1995-03-24 1996-03-13 Diltiazem controlled release formulation

Publications (1)

Publication Number Publication Date
ATE250927T1 true ATE250927T1 (de) 2003-10-15

Family

ID=23620543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96910439T ATE250927T1 (de) 1995-03-24 1996-03-13 Diltiazem-formulierung mit gesteuerter freigabe

Country Status (11)

Country Link
US (2) US5567441A (de)
EP (1) EP0814780B1 (de)
JP (1) JP4381479B2 (de)
CN (1) CN1185104A (de)
AT (1) ATE250927T1 (de)
AU (1) AU697164B2 (de)
CA (1) CA2215378C (de)
DE (1) DE69630215T2 (de)
NZ (1) NZ305594A (de)
TW (1) TW404841B (de)
WO (1) WO1996029992A1 (de)

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* Cited by examiner, † Cited by third party
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AU697164B2 (en) 1998-10-01
DE69630215T2 (de) 2004-07-15
CA2215378A1 (en) 1996-10-03
JP4381479B2 (ja) 2009-12-09
NZ305594A (en) 1998-12-23
CA2215378C (en) 2008-09-16
EP0814780B1 (de) 2003-10-01
EP0814780A4 (de) 2000-03-15
US5834023A (en) 1998-11-10
CN1185104A (zh) 1998-06-17
TW404841B (en) 2000-09-11
WO1996029992A1 (en) 1996-10-03
JPH11502843A (ja) 1999-03-09
US5567441A (en) 1996-10-22
AU5363196A (en) 1996-10-16
DE69630215D1 (de) 2003-11-06
EP0814780A1 (de) 1998-01-07

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