ATE252531T1 - E-2-(4-(chloro-1,2-diphenylbut-1- enyl)phenoxy)ethanol und pharmazeutische zusammensetzungen davon - Google Patents

E-2-(4-(chloro-1,2-diphenylbut-1- enyl)phenoxy)ethanol und pharmazeutische zusammensetzungen davon

Info

Publication number: ATE252531T1
Authority: AT; Austria
Prior art keywords: diphenylbut; enyl; phenoxy; chloro; ethanol
Prior art date: 1998-02-19

Application number

AT99904899T

Other languages

English (en)

Inventor

Marja-Liisa Soedervall

Arja Kalapudas

Antti Viitanen

Eero Maentylae

Original Assignee

Orion Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-19

Filing date

1999-02-19

Publication date

2003-11-15

1999-02-19 Application filed by Orion Corp filed Critical Orion Corp

2003-11-15 Application granted granted Critical

2003-11-15 Publication of ATE252531T1 publication Critical patent/ATE252531T1/de

Links

LUMKNAVTFCDUIE-WCWDXBQESA-N 2-[4-[(e)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]ethanol Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(/CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-WCWDXBQESA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT99904899T 1998-02-19 1999-02-19 E-2-(4-(chloro-1,2-diphenylbut-1- enyl)phenoxy)ethanol und pharmazeutische zusammensetzungen davon ATE252531T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9803521.5A GB9803521D0 (en)	1998-02-19	1998-02-19	New compounds and pharmaceutical compositions thereof
PCT/FI1999/000137 WO1999042427A1 (en)	1998-02-19	1999-02-19	E-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol and pharmaceutical compositions thereof

Publications (1)

Publication Number	Publication Date
ATE252531T1 true ATE252531T1 (de)	2003-11-15

Family

ID=10827263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99904899T ATE252531T1 (de)	1998-02-19	1999-02-19	E-2-(4-(chloro-1,2-diphenylbut-1- enyl)phenoxy)ethanol und pharmazeutische zusammensetzungen davon

Country Status (33)

Country	Link
US (1)	US6395785B1 (de)
EP (1)	EP1056701B1 (de)
JP (1)	JP2002503713A (de)
KR (1)	KR100755918B1 (de)
CN (1)	CN1161314C (de)
AR (1)	AR014961A1 (de)
AT (1)	ATE252531T1 (de)
AU (1)	AU755798B2 (de)
BG (1)	BG64471B1 (de)
BR (1)	BR9907688A (de)
CA (1)	CA2321122C (de)
CZ (1)	CZ294315B6 (de)
DE (1)	DE69912247T2 (de)
DK (1)	DK1056701T3 (de)
EA (1)	EA002919B1 (de)
EE (1)	EE04233B1 (de)
ES (1)	ES2211038T3 (de)
GB (1)	GB9803521D0 (de)
GE (1)	GEP20022794B (de)
HR (1)	HRP20000545A2 (de)
HU (1)	HUP0101354A3 (de)
ID (1)	ID26857A (de)
IL (1)	IL137214A (de)
NO (1)	NO325595B1 (de)
NZ (1)	NZ505637A (de)
PL (1)	PL193315B1 (de)
PT (1)	PT1056701E (de)
RS (1)	RS49660B (de)
SK (1)	SK285940B6 (de)
TR (1)	TR200002037T2 (de)
UA (1)	UA57132C2 (de)
WO (1)	WO1999042427A1 (de)
ZA (1)	ZA991232B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1705169A3 (de) *	1999-11-16	2006-11-15	Hormos Medical Ltd.	Triphenylalkenderivate und ihre Anwendung als selektive Modulatoren des Östrogenrezeptors
TW593256B (en) *	1999-11-16	2004-06-21	Hormos Medical Oy Ltd	Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US20040248989A1 (en)	2003-06-05	2004-12-09	Risto Santti	Method for the treatment or prevention of lower urinary tract symptoms
MX2008014825A (es)	2006-05-22	2008-12-01	Hormos Medical Ltd	Moduladores selectivos del receptor de estrogeno o inhibidores de aromatasa para tratar prostatitis cronica no bacteriana.
WO2008099060A2 (en) *	2007-02-14	2008-08-21	Hormos Medical Ltd	Methods for the preparation of fispemifene from ospemifene
PL2121553T3 (pl)	2007-02-14	2012-11-30	Hormos Medical Ltd	Sposób wytwarzania cennych terapeutycznie pochodnych trifenylobutenu
EP2526080B1 (de)	2010-01-19	2014-03-26	Cambrex Karlskoga AB	Neue verfahren zur herstellung von benzophenonderivaten
US9321712B2 (en)	2012-10-19	2016-04-26	Fermion Oy	Process for the preparation of ospemifene
WO2014060640A1 (en) *	2012-10-19	2014-04-24	Fermion Oy	A process for the preparation of ospemifene
CN104030896A (zh) *	2013-03-07	2014-09-10	天津药物研究院	一种简易去除欧司哌米芬特异杂质的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2126576B (en)	1982-06-25	1985-06-19	Farmos Group Limited	Alkane and alkene derivatives
GB9418067D0 (en) *	1994-09-07	1994-10-26	Orion Yhtymae Oy	Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en) *	1996-03-04	1996-05-01	Orion Yhtymae Oy	Serum cholesterol lowering agent

1998
- 1998-02-19 GB GBGB9803521.5A patent/GB9803521D0/en not_active Ceased
1999
- 1999-02-16 ZA ZA9901232A patent/ZA991232B/xx unknown
- 1999-02-16 AR ARP990100642A patent/AR014961A1/es active IP Right Grant
- 1999-02-19 EE EEP200000473A patent/EE04233B1/xx not_active IP Right Cessation
- 1999-02-19 HU HU0101354A patent/HUP0101354A3/hu unknown
- 1999-02-19 ID IDW20001841A patent/ID26857A/id unknown
- 1999-02-19 BR BR9907688-8A patent/BR9907688A/pt not_active Application Discontinuation
- 1999-02-19 WO PCT/FI1999/000137 patent/WO1999042427A1/en not_active Ceased
- 1999-02-19 AT AT99904899T patent/ATE252531T1/de not_active IP Right Cessation
- 1999-02-19 CZ CZ20002927A patent/CZ294315B6/cs not_active IP Right Cessation
- 1999-02-19 IL IL13721499A patent/IL137214A/xx unknown
- 1999-02-19 CN CNB998030139A patent/CN1161314C/zh not_active Expired - Fee Related
- 1999-02-19 DE DE69912247T patent/DE69912247T2/de not_active Expired - Fee Related
- 1999-02-19 GE GEAP19995553A patent/GEP20022794B/en unknown
- 1999-02-19 CA CA002321122A patent/CA2321122C/en not_active Expired - Fee Related
- 1999-02-19 NZ NZ505637A patent/NZ505637A/xx unknown
- 1999-02-19 RS YUP-510/00A patent/RS49660B/sr unknown
- 1999-02-19 PT PT99904899T patent/PT1056701E/pt unknown
- 1999-02-19 JP JP2000532381A patent/JP2002503713A/ja active Pending
- 1999-02-19 ES ES99904899T patent/ES2211038T3/es not_active Expired - Lifetime
- 1999-02-19 SK SK1205-2000A patent/SK285940B6/sk unknown
- 1999-02-19 PL PL342445A patent/PL193315B1/pl unknown
- 1999-02-19 DK DK99904899T patent/DK1056701T3/da active
- 1999-02-19 UA UA2000095331A patent/UA57132C2/uk unknown
- 1999-02-19 EA EA200000851A patent/EA002919B1/ru not_active IP Right Cessation
- 1999-02-19 TR TR2000/02037T patent/TR200002037T2/xx unknown
- 1999-02-19 AU AU25244/99A patent/AU755798B2/en not_active Ceased
- 1999-02-19 KR KR1020007008982A patent/KR100755918B1/ko not_active Expired - Fee Related
- 1999-02-19 US US09/601,612 patent/US6395785B1/en not_active Expired - Fee Related
- 1999-02-19 EP EP99904899A patent/EP1056701B1/de not_active Expired - Lifetime
- 1999-02-19 HR HR20000545A patent/HRP20000545A2/xx not_active Application Discontinuation
2000
- 2000-08-07 NO NO20003987A patent/NO325595B1/no unknown
- 2000-08-28 BG BG104713A patent/BG64471B1/bg unknown

Also Published As

Publication number	Publication date
HUP0101354A2 (hu)	2002-03-28
DE69912247D1 (de)	2003-11-27
KR20010040985A (ko)	2001-05-15
CA2321122C (en)	2008-02-12
EP1056701A1 (de)	2000-12-06
ID26857A (id)	2001-02-15
CN1291178A (zh)	2001-04-11
CZ20002927A3 (cs)	2000-12-13
IL137214A0 (en)	2001-07-24
EE04233B1 (et)	2004-02-16
GB9803521D0 (en)	1998-04-15
DE69912247T2 (de)	2004-07-29
AU755798B2 (en)	2002-12-19
PT1056701E (pt)	2004-03-31
EA002919B1 (ru)	2002-10-31
GEP20022794B (en)	2002-09-25
WO1999042427A1 (en)	1999-08-26
CA2321122A1 (en)	1999-08-26
TR200002037T2 (tr)	2001-02-21
DK1056701T3 (da)	2004-02-02
AR014961A1 (es)	2001-04-11
BG104713A (bg)	2001-03-30
SK12052000A3 (sk)	2001-01-18
SK285940B6 (sk)	2007-11-02
YU51000A (sh)	2002-11-15
CZ294315B6 (cs)	2004-11-10
IL137214A (en)	2005-05-17
UA57132C2 (uk)	2003-06-16
BG64471B1 (bg)	2005-04-30
US6395785B1 (en)	2002-05-28
HRP20000545A2 (en)	2001-02-28
PL342445A1 (en)	2001-06-04
CN1161314C (zh)	2004-08-11
ZA991232B (en)	1999-09-17
JP2002503713A (ja)	2002-02-05
PL193315B1 (pl)	2007-01-31
NO325595B1 (no)	2008-06-23
RS49660B (sr)	2007-09-21
KR100755918B1 (ko)	2007-09-06
NO20003987L (no)	2000-08-07
AU2524499A (en)	1999-09-06
HUP0101354A3 (en)	2002-05-28
BR9907688A (pt)	2000-11-14
EP1056701B1 (de)	2003-10-22
ES2211038T3 (es)	2004-07-01
NO20003987D0 (no)	2000-08-07
EE200000473A (et)	2001-12-17
NZ505637A (en)	2002-10-25
EA200000851A1 (ru)	2001-02-26

Legal Events

Date

Code

Title

Description

2004-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1056701

Country of ref document: EP

2007-07-15

EEIH

Change in the person of patent owner

2009-11-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FR2775596B1 (fr)	2004-12-24	Nouvelles compositions pharmaceutiques
EE200100391A (et)	2002-10-15	Peptidüül-heterotsüklilised ketoonid, nende kasutamine ja farmatseutiline kompositsioon
FI991485L (fi)	2000-12-31	Uusi farmaseuttinen koostumus
ZA200206905B (en)	2003-08-26	Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same.
ATE228823T1 (de)	2002-12-15	Pharmazeutische aerosolformulierung
EE05193B1 (et)	2009-08-17	Ravimkompositsioonid, mis p?hinevad tiotroopiumbromiidil ja salmeteroolil
EE9900018A (et)	1999-08-16	Asendatud püridiinid, nende kasutamine ja farmatseutilised kompositsioonid
PL355433A1 (pl)	2004-04-19	Indolinony podstawione w pozycji 6, ich wytwarzanie oraz ich zastosowanie w kompozycjach farmaceutycznych
IL152448A0 (en)	2003-05-29	3-nitrogen-6, 7-dioxygen steroid derivatives and pharmaceutical compositions containing the same
NO20010078D0 (no)	2001-01-05	Fenoksyeddiksyrederivat og farmasöytisk sammensetning omfattende det samme
DE69807420D1 (de)	2002-10-02	Pharmazeutische aerosolzusammensetzung
IL150849A0 (en)	2003-02-12	Piperzine and piperidine derivatives and pharmaceutical compositions containg the same
ZA200007299B (en)	2002-04-24	Pharmaceutical compositions and uses for androst-5-ene-3β, 17β-diol.
EE05000B1 (et)	2008-04-15	2'-asendatud 1,1'-bifenüül-2-karboksamiidid, nende kasutamine ja farmatseutilised preparaadid
EE200000225A (et)	2001-06-15	Arüüloksüalküüldialküülamiinid, nende valmistamismeetodid ja farmatseutiline kompositsioon
HUP0202781A3 (en)	2003-10-28	Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use
ZA200308221B (en)	2004-09-29	Pharmaceutical compositions for oral and topical administration.
IL144895A0 (en)	2002-06-30	Pharmaceutical compositions comprising benzaldehyde derivatives and several such new compounds
IL145012A0 (en)	2002-06-30	Fluorine substituted triarylmethane derivatives and pharmaceutical compositions containing the same
ATE252531T1 (de)	2003-11-15	E-2-(4-(chloro-1,2-diphenylbut-1- enyl)phenoxy)ethanol und pharmazeutische zusammensetzungen davon
FR2802423B1 (fr)	2005-03-25	Compositions pharmaceutiques
HUP0203275A3 (en)	2003-11-28	1-cyclic amino-alkylcyclohexane compounds, pharmaceutical compositions thereof, and their use as anticonvulsants
FR2797444B1 (fr)	2003-02-07	Compositions pharmaceutiques comprenant des 4-quinolones
FR2779145B1 (fr)	2004-07-30	Nouvelles compositions pharmaceutiques
NO20014692D0 (no)	2001-09-27	3-amidinobenzensulfonamidderivater, medisinske sammensetninger inneholdende slike samt intermediater vedfremstillingen derav