ATE253917T1 - Nrihydroxstilbene enthaltende produkte und deren derivate und verfahren zur deren herstellung und ihre verwendung - Google Patents
Nrihydroxstilbene enthaltende produkte und deren derivate und verfahren zur deren herstellung und ihre verwendungInfo
- Publication number
- ATE253917T1 ATE253917T1 AT99967471T AT99967471T ATE253917T1 AT E253917 T1 ATE253917 T1 AT E253917T1 AT 99967471 T AT99967471 T AT 99967471T AT 99967471 T AT99967471 T AT 99967471T AT E253917 T1 ATE253917 T1 AT E253917T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- methods
- nrihydroxistilbenes
- production
- products
- Prior art date
Links
- 239000000203 mixture Substances 0.000 abstract 3
- LXOPCHVYWBGPND-UHFFFAOYSA-N 4-(2-phenylethenyl)benzene-1,2,3-triol Chemical class OC1=C(O)C(O)=CC=C1C=CC1=CC=CC=C1 LXOPCHVYWBGPND-UHFFFAOYSA-N 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000003125 aqueous solvent Substances 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/217,642 US6361815B1 (en) | 1998-12-21 | 1998-12-21 | Products comprising trihydroxystilbenes and derivatives thereof and methods for their manufacture and use |
| PCT/US1999/030425 WO2000037021A2 (en) | 1998-12-21 | 1999-12-21 | Products comprising trihydroxystilbenes and derivatives thereof and methods for their manufacture and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE253917T1 true ATE253917T1 (de) | 2003-11-15 |
Family
ID=22811901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99967471T ATE253917T1 (de) | 1998-12-21 | 1999-12-21 | Nrihydroxstilbene enthaltende produkte und deren derivate und verfahren zur deren herstellung und ihre verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6361815B1 (de) |
| EP (1) | EP1140097B1 (de) |
| AT (1) | ATE253917T1 (de) |
| AU (1) | AU2374100A (de) |
| CA (1) | CA2394949A1 (de) |
| DE (1) | DE69912839T2 (de) |
| ES (1) | ES2211219T3 (de) |
| WO (1) | WO2000037021A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1317033B1 (it) * | 2000-05-30 | 2003-05-26 | Istituto Di Medicina Speriment | Metodo di estrazione di prodotti ad attivita' farmaceutica da piantespermatofite, prodotti cosi' ottenuti e loro impiego in medicina, in |
| KR100515066B1 (ko) * | 2002-04-22 | 2005-09-14 | 한국생명공학연구원 | 박새로부터 분리한 타이로시네이즈 저해활성을 가지는화합물 및 이를 포함하는 피부미백제 |
| US7977049B2 (en) * | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| US20060025337A1 (en) * | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| JP2007530417A (ja) | 2003-07-01 | 2007-11-01 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 細胞及び生物の寿命及びストレス応答を操作するための組成物 |
| US8017634B2 (en) | 2003-12-29 | 2011-09-13 | President And Fellows Of Harvard College | Compositions for treating obesity and insulin resistance disorders |
| US20050171027A1 (en) | 2003-12-29 | 2005-08-04 | President And Fellows Of Harvard College | Compositions for treating or preventing obesity and insulin resistance disorders |
| BRPI0402260B1 (pt) * | 2004-06-15 | 2015-02-18 | Botica Com Farmaceutica Ltda | Composição para produtos de higiene, cosméticos e perfumes. |
| US20060084085A1 (en) * | 2004-06-16 | 2006-04-20 | Sinclair David A | Methods and compositions for modulating Bax-mediated apoptosis |
| EP1843745A1 (de) * | 2005-02-04 | 2007-10-17 | Peter Heger | Dosierungsformen hydroxystilben-haltiger wirkstoffe zur behandlung klimakterischer beschwerden |
| EP1843758B1 (de) | 2005-02-04 | 2014-09-24 | Peter Heger | Verwendung einer hydroxystilben-haltigen wirkstoffkombination zur behandlung von prostatakrebs und/oder von luts |
| WO2006138418A2 (en) * | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| WO2007110883A1 (en) | 2006-03-28 | 2007-10-04 | Council Of Scientific & Industrial Research | A single step microwave induced process for the preparation of substituted stilbenes and its analogs |
| CN102300578A (zh) * | 2008-12-01 | 2011-12-28 | 延寿有限责任公司 | 用于改变健康、安康和寿命的方法和组合物 |
| US20100215769A1 (en) * | 2009-02-24 | 2010-08-26 | Pero Ronald W | Natural occurring nutrient supplement compositions and methods of treatment using same by improving resistance to DNA damage, enhancing DNA repair and stimulating immune function wherein metabolic competition is avoided |
| WO2010113005A2 (en) | 2009-03-27 | 2010-10-07 | Council Of Scientific & Industrial Research | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation |
| WO2013003112A1 (en) | 2011-06-27 | 2013-01-03 | The Jackson Laboratory | Methods and compositions for treatment of cancer and autoimmune disease |
| WO2013149258A2 (en) | 2012-03-30 | 2013-10-03 | Charles Drew University of Medicine and Science | Compositions and methods for treating or preventing metabolic syndrome disorders |
| TW201702218A (zh) | 2014-12-12 | 2017-01-16 | 美國杰克森實驗室 | 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS609455A (ja) | 1983-06-27 | 1985-01-18 | Osaka Chem Lab | 特定たで科植物から抽出されたスチルベン化合物を主要成分とする食品 |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| US6238673B1 (en) * | 1996-09-20 | 2001-05-29 | The Howard Foundation | Method of producing high flavonol content polyphenol compositions |
| CN1055859C (zh) * | 1997-04-16 | 2000-08-30 | 中国人民解放军空军总医院 | 芪类化合物及其衍生物在制备内皮素拮抗剂中的应用 |
| US6008260A (en) * | 1998-01-09 | 1999-12-28 | Pharmascience | Cancer chemopreventative composition and method |
| US6022901A (en) * | 1998-05-13 | 2000-02-08 | Pharmascience Inc. | Administration of resveratrol to prevent or treat restenosis following coronary intervention |
| FR2795965B1 (fr) * | 1999-07-08 | 2002-12-27 | Actichem | Procede de fabrication d'un extrait naturel de la vigne concentre en reseratrol et produits |
-
1998
- 1998-12-21 US US09/217,642 patent/US6361815B1/en not_active Expired - Lifetime
-
1999
- 1999-12-21 EP EP99967471A patent/EP1140097B1/de not_active Expired - Lifetime
- 1999-12-21 AT AT99967471T patent/ATE253917T1/de not_active IP Right Cessation
- 1999-12-21 AU AU23741/00A patent/AU2374100A/en not_active Abandoned
- 1999-12-21 ES ES99967471T patent/ES2211219T3/es not_active Expired - Lifetime
- 1999-12-21 WO PCT/US1999/030425 patent/WO2000037021A2/en not_active Ceased
- 1999-12-21 DE DE69912839T patent/DE69912839T2/de not_active Expired - Fee Related
- 1999-12-21 CA CA002394949A patent/CA2394949A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000037021A2 (en) | 2000-06-29 |
| ES2211219T3 (es) | 2004-07-01 |
| WO2000037021A3 (en) | 2000-09-08 |
| DE69912839D1 (de) | 2003-12-18 |
| EP1140097A2 (de) | 2001-10-10 |
| CA2394949A1 (en) | 2000-06-29 |
| US6361815B1 (en) | 2002-03-26 |
| EP1140097B1 (de) | 2003-11-12 |
| AU2374100A (en) | 2000-07-12 |
| DE69912839T2 (de) | 2004-11-11 |
| EP1140097A4 (de) | 2002-05-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |