ATE254455T1 - Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel - Google Patents

Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel

Info

Publication number: ATE254455T1
Authority: AT; Austria
Prior art keywords: water; mixable; pharmaceutical compositions; compositions containing; containing paclitaxel
Prior art date: 1998-10-30

Application number

AT99951559T

Other languages

English (en)

Inventor

Joseph Rubinfeld

Rajashree Joshi

Ashok Y Gore

Rajesh Shrotriya

Original Assignee

Supergen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-30

Filing date

1999-09-22

Publication date

2003-12-15

1999-09-22 Application filed by Supergen Inc filed Critical Supergen Inc

2003-12-15 Application granted granted Critical

2003-12-15 Publication of ATE254455T1 publication Critical patent/ATE254455T1/de

Links

229930012538 Paclitaxel Natural products 0.000 title abstract 2
229960001592 paclitaxel Drugs 0.000 title abstract 2
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
239000003125 aqueous solvent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT99951559T 1998-10-30 1999-09-22 Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel ATE254455T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/183,199 US6017948A (en)	1998-10-30	1998-10-30	Water-miscible pharmaceutical compositions
PCT/US1999/021990 WO2000025775A1 (en)	1998-10-30	1999-09-22	Water-miscible pharmaceutical compositions of paclitaxel

Publications (1)

Publication Number	Publication Date
ATE254455T1 true ATE254455T1 (de)	2003-12-15

Family

ID=22671864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99951559T ATE254455T1 (de)	1998-10-30	1999-09-22	Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel

Country Status (11)

Country	Link
US (1)	US6017948A (de)
EP (1)	EP1124549B1 (de)
JP (1)	JP2002528494A (de)
CN (1)	CN1178655C (de)
AT (1)	ATE254455T1 (de)
AU (1)	AU775158B2 (de)
CA (1)	CA2345697A1 (de)
DE (1)	DE69912983D1 (de)
IL (1)	IL142720A (de)
MX (1)	MXPA01004268A (de)
WO (1)	WO2000025775A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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US6774278B1 (en) *	1995-06-07	2004-08-10	Cook Incorporated	Coated implantable medical device
US6071952A (en) *	1998-12-02	2000-06-06	Mylan Pharmaceuticals, Inc.	Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
US6040330A (en) *	1999-01-08	2000-03-21	Bionumerik Pharmaceuticals, Inc.	Pharmaceutical formulations of taxanes
US6828346B2 (en) *	1999-10-25	2004-12-07	Supergen, Inc.	Methods for administration of paclitaxel
US6136846A (en)	1999-10-25	2000-10-24	Supergen, Inc.	Formulation for paclitaxel
CA2410632A1 (en)	2000-06-22	2001-12-27	David S. Garvey	Nitrosated and nitrosylated taxanes, compositions and methods of use
CA2440935A1 (en) *	2001-03-13	2002-09-19	Richard Liggins	Micellar drug delivery vehicles and precursors thereto and uses thereof
DE10115740A1 (de)	2001-03-26	2002-10-02	Ulrich Speck	Zubereitung für die Restenoseprophylaxe
DE60220519T2 (de)	2001-04-20	2007-09-27	The University Of British Columbia, Vancouver	Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe
US20030126788A1 (en) *	2001-11-07	2003-07-10	Colloid Tech. Inc.	Storage stable translucent flammable article
US6537985B1 (en)	2001-11-30	2003-03-25	Phoenix Scientific, Inc.	Antibiotic formulation and a method of making this formulation
PL368945A1 (en) *	2001-11-30	2005-04-04	Bristol-Myers Squibb Company	Paclitaxel solvates
ATE424187T1 (de) *	2002-07-15	2009-03-15	Alcon Inc	Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels
DE10244847A1 (de)	2002-09-20	2004-04-01	Ulrich Prof. Dr. Speck	Medizinische Vorrichtung zur Arzneimittelabgabe
EP1896040B1 (de)	2005-06-29	2012-08-01	Threshold Pharmaceuticals, Inc.	Phosphoramidat-alkylator-prodrugs
US9943490B2 (en)	2007-11-05	2018-04-17	The Trustees Of Princeton University	Composite flash-precipitated nanoparticles
WO2009087678A2 (en) *	2007-12-24	2009-07-16	Sun Pharma Advanced Research Company Limited	Nanodispersion
EP2350664B1 (de) *	2008-10-21	2021-05-19	ImmunoGenesis, Inc.	Behandlung von krebs anhand vom hypoxie-aktivierten promedikament th-302 in kombinatin mit docetaxel oder pemetrexed
EP2442805A4 (de)	2009-06-19	2012-11-21	Sun Pharma Advanced Res Co Ltd	Nanodispersion aus einem medikament und verfahren zu ihrer herstellung
US10842770B2 (en)	2010-05-03	2020-11-24	Teikoku Pharma Usa, Inc.	Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
WO2012092421A2 (en) *	2010-12-30	2012-07-05	Surmodics, Inc.	Composition for intravascular delivery of therapeutic composition
JO3685B1 (ar)	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN112972419B (zh) *	2019-12-02	2024-03-08	四川科伦药物研究院有限公司	一种白蛋白纳米药物组合物的制备方法

Family Cites Families (17)

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Publication number	Priority date	Publication date	Assignee	Title
IE74244B1 (en) *	1985-10-01	1997-07-16	Bimeda Res Dev Ltd	A process for preparing an antibiotic composition
US5034397A (en) *	1985-12-12	1991-07-23	Bristol-Myers Squibb Co.	Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone
US4772589A (en) *	1986-10-29	1988-09-20	Bristol-Myers	Etoposide solution in NMP
AU630469B2 (en) *	1989-05-26	1992-10-29	Abbott Laboratories	Injectable clarithromycin composition
US5082863A (en) *	1990-08-29	1992-01-21	Schering Corporation	Pharmaceutical composition of florfenicol
CA2086874E (en) *	1992-08-03	2000-01-04	Renzo Mauro Canetta	Methods for administration of taxol
EP0626171A1 (de) *	1993-05-26	1994-11-30	Winfried Dörnhöfer	Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
TW406020B (en) *	1993-09-29	2000-09-21	Bristol Myers Squibb Co	Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
ES2128761T3 (es) *	1994-09-01	1999-05-16	Upjohn Co	Formulacion de tirilazad con cosolvente para administracion parenteral.
AU4652596A (en) *	1995-01-09	1996-07-31	Atrix Laboratories, Inc.	Liquid polymer delivery system
US5681846A (en) *	1995-03-17	1997-10-28	Board Of Regents, The University Of Texas System	Extended stability formulations for paclitaxel
US5726181A (en) *	1995-06-05	1998-03-10	Bionumerik Pharmaceuticals, Inc.	Formulations and compositions of poorly water soluble camptothecin derivatives
EP0868183B1 (de) *	1995-12-21	2002-01-30	Pfizer Inc.	Injizierbare quinolonformulierungen
US5773422A (en) *	1996-01-29	1998-06-30	Komer; Gene	Avermectin formulation
US5877205A (en) *	1996-06-28	1999-03-02	Board Of Regents, The University Of Texas System	Parenteral paclitaxel in a stable non-toxic formulation
CA2211949A1 (en) *	1997-07-21	1999-01-29	David Farley Johnson	Nonaqueous compositions for parenteral administration
US5922754A (en) *	1998-10-02	1999-07-13	Abbott Laboratories	Pharmaceutical compositions containing paclitaxel

1998
- 1998-10-30 US US09/183,199 patent/US6017948A/en not_active Expired - Fee Related
1999
- 1999-09-22 MX MXPA01004268A patent/MXPA01004268A/es not_active IP Right Cessation
- 1999-09-22 DE DE69912983T patent/DE69912983D1/de not_active Expired - Lifetime
- 1999-09-22 JP JP2000579216A patent/JP2002528494A/ja active Pending
- 1999-09-22 CA CA002345697A patent/CA2345697A1/en not_active Abandoned
- 1999-09-22 AU AU63977/99A patent/AU775158B2/en not_active Ceased
- 1999-09-22 CN CNB998126624A patent/CN1178655C/zh not_active Expired - Fee Related
- 1999-09-22 AT AT99951559T patent/ATE254455T1/de not_active IP Right Cessation
- 1999-09-22 WO PCT/US1999/021990 patent/WO2000025775A1/en not_active Ceased
- 1999-09-22 EP EP99951559A patent/EP1124549B1/de not_active Expired - Lifetime
- 1999-09-22 IL IL14272099A patent/IL142720A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU6397799A (en)	2000-05-22
EP1124549A1 (de)	2001-08-22
IL142720A (en)	2005-03-20
DE69912983D1 (de)	2003-12-24
MXPA01004268A (es)	2002-06-04
EP1124549B1 (de)	2003-11-19
CA2345697A1 (en)	2000-05-11
AU775158B2 (en)	2004-07-22
US6017948A (en)	2000-01-25
CN1178655C (zh)	2004-12-08
WO2000025775A1 (en)	2000-05-11
JP2002528494A (ja)	2002-09-03
CN1368880A (zh)	2002-09-11
IL142720A0 (en)	2002-03-10

Legal Events

Date	Code	Title	Description
2004-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE254455T1 (de)	2003-12-15	Wassermischbare pharmazeutische zusammensetzungen enthaltend paclitaxel
DE50004352D1 (de)	2003-12-11	Farbmittelzubereitungen
BR0215405A (pt)	2005-01-25	Composições e processos de uso de collajolie
ITRM20020411A0 (it)	2002-08-01	Derivati dello spirobifluorene, loro preparazione e loro uso.
BR9915515B1 (pt)	2008-11-18	composiÇço curÁvel de multicomponentes.
WO2004045001A3 (en)	2004-09-23	Organic light emitting materials and devices
AU2001274078A1 (en)	2001-12-11	Prepolymeric (meth)acrylates with polycyclic or aromatic segments
NO20003930L (no)	2000-10-04	Sammensetninger som inneholder organiske forbindelser
BR0300500B1 (pt)	2013-03-05	composiÇço poliolefÍnica, processo para estabilizaÇço de uma poliolefina e uso de uma mistura.
SV2004001432A (es)	2004-02-24	2-tio-3,5-diciano-4-4fenil-6-aminopiridinas substituidas y su uso ref. lea 35 640-sv
NO20032252D0 (no)	2003-05-19	Piperazinylpyrazinforbindelser som agonist eller antagonist av serotonin 5HT-2-reseptor
DE59903442D1 (de)	2003-01-02	Azidfreie, gaserzeugende Zusammensetzung
WO2001087824A3 (en)	2002-04-11	7-substituted fused ring tetracycline compounds
EA199900373A2 (ru)	1999-12-29	Фармацевтические композиции
HRP20070374T3 (en)	2007-10-31	Formulations comprising ecteinascidin and a disaccharide
BR0317593A (pt)	2005-11-22	Formas de dosagem compreendendo um inibidor de cetp e um inibidor de hmg-coa reductase
AR028162A1 (es)	2003-04-30	Disponibilidad controlada de compuestos de formulacion, composiciones y metodos para el lavado que utilizan los mismos.
NO20031648L (no)	2003-06-04	Farmasöytiske lösninger av modafinilforbindelser
ECSP034531A (es)	2003-05-26	Derivados sustituidos de c-ciclohexilmetilamina
PA8577701A1 (es)	2004-02-07	Polipeptido t20 pegilado
ATE441626T1 (de)	2009-09-15	Azeotropähnliche zusammensetzungen und deren verwendung
ID21353A (id)	1999-05-27	Senyawa bi-aromatik yang terikat melalui radikal heteroetilena, serta komposisi farmasi dan kosmetik yang mengandungnya
HN2000000056A (es)	2001-02-02	Nuevas formas cristalinas de un antibiotico macrolido
EA200400670A1 (ru)	2004-10-28	Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи
EA200300128A1 (ru)	2003-08-28	Фармацевтические композиции, содержащие карбонат лития