IL142720A - Water-miscible pharmaceutical compositions of paclitaxel - Google Patents
Water-miscible pharmaceutical compositions of paclitaxelInfo
- Publication number
- IL142720A IL142720A IL14272099A IL14272099A IL142720A IL 142720 A IL142720 A IL 142720A IL 14272099 A IL14272099 A IL 14272099A IL 14272099 A IL14272099 A IL 14272099A IL 142720 A IL142720 A IL 142720A
- Authority
- IL
- Israel
- Prior art keywords
- paclitaxel
- water
- pharmaceutical compositions
- miscible pharmaceutical
- miscible
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 2
- 229960001592 paclitaxel Drugs 0.000 title abstract 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 239000003125 aqueous solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/183,199 US6017948A (en) | 1998-10-30 | 1998-10-30 | Water-miscible pharmaceutical compositions |
| PCT/US1999/021990 WO2000025775A1 (en) | 1998-10-30 | 1999-09-22 | Water-miscible pharmaceutical compositions of paclitaxel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL142720A0 IL142720A0 (en) | 2002-03-10 |
| IL142720A true IL142720A (en) | 2005-03-20 |
Family
ID=22671864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14272099A IL142720A (en) | 1998-10-30 | 1999-09-22 | Water-miscible pharmaceutical compositions of paclitaxel |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6017948A (de) |
| EP (1) | EP1124549B1 (de) |
| JP (1) | JP2002528494A (de) |
| CN (1) | CN1178655C (de) |
| AT (1) | ATE254455T1 (de) |
| AU (1) | AU775158B2 (de) |
| CA (1) | CA2345697A1 (de) |
| DE (1) | DE69912983D1 (de) |
| IL (1) | IL142720A (de) |
| MX (1) | MXPA01004268A (de) |
| WO (1) | WO2000025775A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| US6071952A (en) * | 1998-12-02 | 2000-06-06 | Mylan Pharmaceuticals, Inc. | Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents |
| US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
| US6828346B2 (en) * | 1999-10-25 | 2004-12-07 | Supergen, Inc. | Methods for administration of paclitaxel |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| JP2004501143A (ja) | 2000-06-22 | 2004-01-15 | ニトロメド インコーポレーテッド | ニトロソ化およびニトロシル化タキサン、組成物および使用方法 |
| CA2440935A1 (en) * | 2001-03-13 | 2002-09-19 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| DE10115740A1 (de) | 2001-03-26 | 2002-10-02 | Ulrich Speck | Zubereitung für die Restenoseprophylaxe |
| EP1392254B1 (de) | 2001-04-20 | 2007-06-06 | The University of British Columbia | Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe |
| US20030126788A1 (en) * | 2001-11-07 | 2003-07-10 | Colloid Tech. Inc. | Storage stable translucent flammable article |
| US6537985B1 (en) | 2001-11-30 | 2003-03-25 | Phoenix Scientific, Inc. | Antibiotic formulation and a method of making this formulation |
| KR20050044621A (ko) * | 2001-11-30 | 2005-05-12 | 브리스톨-마이어스 스큅 컴퍼니 | 파클리탁셀 용매화물 |
| ATE424187T1 (de) * | 2002-07-15 | 2009-03-15 | Alcon Inc | Bioerodierbare folie zur abgabe eines ophthalmischen arzneimittels |
| DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
| AU2006263433B8 (en) | 2005-06-29 | 2011-06-09 | Immunogenesis, Inc. | Phosphoramidate alkylator prodrugs |
| US9943490B2 (en) * | 2007-11-05 | 2018-04-17 | The Trustees Of Princeton University | Composite flash-precipitated nanoparticles |
| DK2231144T3 (da) * | 2007-12-24 | 2014-10-13 | Sun Pharma Advanced Res Co Ltd | Nanodispersion |
| US8946275B2 (en) | 2008-10-21 | 2015-02-03 | Threshold Pharmaceuticals, Inc. | Treatment of cancer using hypoxia activated prodrugs |
| CA2765541A1 (en) | 2009-06-19 | 2010-12-23 | Sun Pharma Advanced Research Company Ltd. | Nanodispersion of a drug and process for its preparation |
| CA2798180A1 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| US20120172796A1 (en) | 2010-12-30 | 2012-07-05 | Chappa Ralph A | Composition for intravascular delivery of therapeutic composition |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CN112972419B (zh) * | 2019-12-02 | 2024-03-08 | 四川科伦药物研究院有限公司 | 一种白蛋白纳米药物组合物的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE74244B1 (en) * | 1985-10-01 | 1997-07-16 | Bimeda Res Dev Ltd | A process for preparing an antibiotic composition |
| US5034397A (en) * | 1985-12-12 | 1991-07-23 | Bristol-Myers Squibb Co. | Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone |
| US4772589A (en) * | 1986-10-29 | 1988-09-20 | Bristol-Myers | Etoposide solution in NMP |
| WO1990014094A1 (en) * | 1989-05-26 | 1990-11-29 | Abbott Laboratories | Injectable clarithromycin composition |
| US5082863A (en) * | 1990-08-29 | 1992-01-21 | Schering Corporation | Pharmaceutical composition of florfenicol |
| CA2086874E (en) * | 1992-08-03 | 2000-01-04 | Renzo Mauro Canetta | Methods for administration of taxol |
| EP0626171A1 (de) * | 1993-05-26 | 1994-11-30 | Winfried Dörnhöfer | Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere |
| TW406020B (en) * | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
| ATE175875T1 (de) * | 1994-09-01 | 1999-02-15 | Upjohn Co | Tirilazad parentale formulierung mit einem co- lösungsmittel |
| AU4652596A (en) * | 1995-01-09 | 1996-07-31 | Atrix Laboratories, Inc. | Liquid polymer delivery system |
| US5681846A (en) * | 1995-03-17 | 1997-10-28 | Board Of Regents, The University Of Texas System | Extended stability formulations for paclitaxel |
| US5726181A (en) * | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
| PL186795B1 (pl) * | 1995-12-21 | 2004-02-27 | Pfizer | Preparat farmaceutyczny zawierający danofloksacynę |
| US5773422A (en) * | 1996-01-29 | 1998-06-30 | Komer; Gene | Avermectin formulation |
| US5877205A (en) * | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
| CA2211949A1 (en) * | 1997-07-21 | 1999-01-29 | David Farley Johnson | Nonaqueous compositions for parenteral administration |
| US5922754A (en) * | 1998-10-02 | 1999-07-13 | Abbott Laboratories | Pharmaceutical compositions containing paclitaxel |
-
1998
- 1998-10-30 US US09/183,199 patent/US6017948A/en not_active Expired - Fee Related
-
1999
- 1999-09-22 CA CA002345697A patent/CA2345697A1/en not_active Abandoned
- 1999-09-22 MX MXPA01004268A patent/MXPA01004268A/es not_active IP Right Cessation
- 1999-09-22 WO PCT/US1999/021990 patent/WO2000025775A1/en not_active Ceased
- 1999-09-22 CN CNB998126624A patent/CN1178655C/zh not_active Expired - Fee Related
- 1999-09-22 IL IL14272099A patent/IL142720A/xx not_active IP Right Cessation
- 1999-09-22 EP EP99951559A patent/EP1124549B1/de not_active Expired - Lifetime
- 1999-09-22 AU AU63977/99A patent/AU775158B2/en not_active Ceased
- 1999-09-22 DE DE69912983T patent/DE69912983D1/de not_active Expired - Lifetime
- 1999-09-22 AT AT99951559T patent/ATE254455T1/de not_active IP Right Cessation
- 1999-09-22 JP JP2000579216A patent/JP2002528494A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01004268A (es) | 2002-06-04 |
| DE69912983D1 (de) | 2003-12-24 |
| EP1124549A1 (de) | 2001-08-22 |
| JP2002528494A (ja) | 2002-09-03 |
| ATE254455T1 (de) | 2003-12-15 |
| CN1368880A (zh) | 2002-09-11 |
| EP1124549B1 (de) | 2003-11-19 |
| IL142720A0 (en) | 2002-03-10 |
| CN1178655C (zh) | 2004-12-08 |
| WO2000025775A1 (en) | 2000-05-11 |
| AU775158B2 (en) | 2004-07-22 |
| AU6397799A (en) | 2000-05-22 |
| CA2345697A1 (en) | 2000-05-11 |
| US6017948A (en) | 2000-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |