IL142720A - Water-miscible pharmaceutical compositions of paclitaxel - Google Patents

Water-miscible pharmaceutical compositions of paclitaxel

Info

Publication number: IL142720A
Authority: IL; Israel
Prior art keywords: paclitaxel; water; pharmaceutical compositions; miscible pharmaceutical; miscible
Prior art date: 1998-10-30

Application number

IL14272099A

Other languages

English (en)

Other versions

IL142720A0 (en

Original Assignee

Supergen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-30

Filing date

1999-09-22

Publication date

2005-03-20

1999-09-22 Application filed by Supergen Inc filed Critical Supergen Inc

2002-03-10 Publication of IL142720A0 publication Critical patent/IL142720A0/xx

2005-03-20 Publication of IL142720A publication Critical patent/IL142720A/xx

Links

229930012538 Paclitaxel Natural products 0.000 title abstract 2
229960001592 paclitaxel Drugs 0.000 title abstract 2
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
239000003125 aqueous solvent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

IL14272099A 1998-10-30 1999-09-22 Water-miscible pharmaceutical compositions of paclitaxel IL142720A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/183,199 US6017948A (en)	1998-10-30	1998-10-30	Water-miscible pharmaceutical compositions
PCT/US1999/021990 WO2000025775A1 (en)	1998-10-30	1999-09-22	Water-miscible pharmaceutical compositions of paclitaxel

Publications (2)

Publication Number	Publication Date
IL142720A0 IL142720A0 (en)	2002-03-10
IL142720A true IL142720A (en)	2005-03-20

Family

ID=22671864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14272099A IL142720A (en)	1998-10-30	1999-09-22	Water-miscible pharmaceutical compositions of paclitaxel

Country Status (11)

Country	Link
US (1)	US6017948A (de)
EP (1)	EP1124549B1 (de)
JP (1)	JP2002528494A (de)
CN (1)	CN1178655C (de)
AT (1)	ATE254455T1 (de)
AU (1)	AU775158B2 (de)
CA (1)	CA2345697A1 (de)
DE (1)	DE69912983D1 (de)
IL (1)	IL142720A (de)
MX (1)	MXPA01004268A (de)
WO (1)	WO2000025775A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6774278B1 (en) *	1995-06-07	2004-08-10	Cook Incorporated	Coated implantable medical device
US6071952A (en) *	1998-12-02	2000-06-06	Mylan Pharmaceuticals, Inc.	Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
US6040330A (en) *	1999-01-08	2000-03-21	Bionumerik Pharmaceuticals, Inc.	Pharmaceutical formulations of taxanes
US6828346B2 (en) *	1999-10-25	2004-12-07	Supergen, Inc.	Methods for administration of paclitaxel
US6136846A (en) *	1999-10-25	2000-10-24	Supergen, Inc.	Formulation for paclitaxel
CA2410632A1 (en)	2000-06-22	2001-12-27	David S. Garvey	Nitrosated and nitrosylated taxanes, compositions and methods of use
EP1418945A2 (de) *	2001-03-13	2004-05-19	Angiotech Pharmaceuticals, Inc.	Mizellare arzneimittelabgabe vehikel und ihre anwendungen
DE10115740A1 (de)	2001-03-26	2002-10-02	Ulrich Speck	Zubereitung für die Restenoseprophylaxe
JP2004532847A (ja)	2001-04-20	2004-10-28	ザユニヴァーシティオヴブリティッシュコロンビア	疎水性薬物のためのミセル薬物送達システム
US20030126788A1 (en) *	2001-11-07	2003-07-10	Colloid Tech. Inc.	Storage stable translucent flammable article
WO2003047508A2 (en) *	2001-11-30	2003-06-12	Bristol-Myers Squibb Company	Paclitaxel solvates
US6537985B1 (en)	2001-11-30	2003-03-25	Phoenix Scientific, Inc.	Antibiotic formulation and a method of making this formulation
PL206379B1 (pl) *	2002-07-15	2010-08-31	Alcon	Ulegająca bioerozji kompozycja do wytwarzania błony do dostarczania leków oftalmicznych i zastosowanie
DE10244847A1 (de)	2002-09-20	2004-04-01	Ulrich Prof. Dr. Speck	Medizinische Vorrichtung zur Arzneimittelabgabe
ZA200800314B (en)	2005-06-29	2009-09-30	Threshold Pharmaceuticals Inc	Phosphoramidate alkylator prodrugs
US9943490B2 (en) *	2007-11-05	2018-04-17	The Trustees Of Princeton University	Composite flash-precipitated nanoparticles
PL2231144T3 (pl) *	2007-12-24	2014-12-31	Sun Pharma Advanced Res Co Ltd	Nanodyspersja
WO2010048330A1 (en) *	2008-10-21	2010-04-29	Threshold Pharmaceuticals, Inc.	Treatment of cancer using hypoxia activated prodrugs
US8778364B2 (en)	2009-06-19	2014-07-15	Sun Pharma Advanced Research Company Ltd.	Nanodispersion of a drug and process for its preparation
JP5824511B2 (ja)	2010-05-03	2015-11-25	テイコクファーマユーエスエーインコーポレーテッド	非水タキサンプロエマルジョン配合物ならびにそれを調製および使用する方法
US20120172796A1 (en) *	2010-12-30	2012-07-05	Chappa Ralph A	Composition for intravascular delivery of therapeutic composition
JO3685B1 (ar)	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN112972419B (zh) *	2019-12-02	2024-03-08	四川科伦药物研究院有限公司	一种白蛋白纳米药物组合物的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE74244B1 (en) *	1985-10-01	1997-07-16	Bimeda Res Dev Ltd	A process for preparing an antibiotic composition
US5034397A (en) *	1985-12-12	1991-07-23	Bristol-Myers Squibb Co.	Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone
US4772589A (en) *	1986-10-29	1988-09-20	Bristol-Myers	Etoposide solution in NMP
JP2963537B2 (ja) *	1989-05-26	1999-10-18	アボツト・ラボラトリーズ	クラリトロマイシンの注射用組成物
US5082863A (en) *	1990-08-29	1992-01-21	Schering Corporation	Pharmaceutical composition of florfenicol
CA2086874E (en) *	1992-08-03	2000-01-04	Renzo Mauro Canetta	Methods for administration of taxol
EP0626171A1 (de) *	1993-05-26	1994-11-30	Winfried Dörnhöfer	Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
TW406020B (en) *	1993-09-29	2000-09-21	Bristol Myers Squibb Co	Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
DE69507493T2 (de) *	1994-09-01	1999-06-10	Upjohn Co	Tirilazad parentale formulierung mit einem co-lösungsmittel
AU4652596A (en) *	1995-01-09	1996-07-31	Atrix Laboratories, Inc.	Liquid polymer delivery system
US5681846A (en) *	1995-03-17	1997-10-28	Board Of Regents, The University Of Texas System	Extended stability formulations for paclitaxel
US5726181A (en) *	1995-06-05	1998-03-10	Bionumerik Pharmaceuticals, Inc.	Formulations and compositions of poorly water soluble camptothecin derivatives
CZ293747B6 (cs) *	1995-12-21	2004-07-14	Pfizer Inc.	Vodný farmaceutický roztok vhodný pro injekční podávání hostiteli a jeho použití
US5773422A (en) *	1996-01-29	1998-06-30	Komer; Gene	Avermectin formulation
US5877205A (en) *	1996-06-28	1999-03-02	Board Of Regents, The University Of Texas System	Parenteral paclitaxel in a stable non-toxic formulation
CA2211949A1 (en) *	1997-07-21	1999-01-29	David Farley Johnson	Nonaqueous compositions for parenteral administration
US5922754A (en) *	1998-10-02	1999-07-13	Abbott Laboratories	Pharmaceutical compositions containing paclitaxel

1998
- 1998-10-30 US US09/183,199 patent/US6017948A/en not_active Expired - Fee Related
1999
- 1999-09-22 JP JP2000579216A patent/JP2002528494A/ja active Pending
- 1999-09-22 AT AT99951559T patent/ATE254455T1/de not_active IP Right Cessation
- 1999-09-22 WO PCT/US1999/021990 patent/WO2000025775A1/en not_active Ceased
- 1999-09-22 AU AU63977/99A patent/AU775158B2/en not_active Ceased
- 1999-09-22 CA CA002345697A patent/CA2345697A1/en not_active Abandoned
- 1999-09-22 DE DE69912983T patent/DE69912983D1/de not_active Expired - Lifetime
- 1999-09-22 IL IL14272099A patent/IL142720A/xx not_active IP Right Cessation
- 1999-09-22 EP EP99951559A patent/EP1124549B1/de not_active Expired - Lifetime
- 1999-09-22 MX MXPA01004268A patent/MXPA01004268A/es not_active IP Right Cessation
- 1999-09-22 CN CNB998126624A patent/CN1178655C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MXPA01004268A (es)	2002-06-04
WO2000025775A1 (en)	2000-05-11
EP1124549B1 (de)	2003-11-19
IL142720A0 (en)	2002-03-10
AU6397799A (en)	2000-05-22
JP2002528494A (ja)	2002-09-03
AU775158B2 (en)	2004-07-22
ATE254455T1 (de)	2003-12-15
DE69912983D1 (de)	2003-12-24
CN1368880A (zh)	2002-09-11
EP1124549A1 (de)	2001-08-22
US6017948A (en)	2000-01-25
CA2345697A1 (en)	2000-05-11
CN1178655C (zh)	2004-12-08

Legal Events

Date	Code	Title
2005-09-25	FF	Patent granted
2005-09-25	KB	Patent renewed
2010-11-30	MM9K	Patent not in force due to non-payment of renewal fees

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