ATE255564T1 - Imidazolderivat - Google Patents
ImidazolderivatInfo
- Publication number
- ATE255564T1 ATE255564T1 AT95932231T AT95932231T ATE255564T1 AT E255564 T1 ATE255564 T1 AT E255564T1 AT 95932231 T AT95932231 T AT 95932231T AT 95932231 T AT95932231 T AT 95932231T AT E255564 T1 ATE255564 T1 AT E255564T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- imidazole derivative
- halogeno
- formula
- hydrogen
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000006823 (C1-C6) acyl group Chemical group 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxyiminomethyl Chemical group 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25749094 | 1994-09-26 | ||
| JP8469095 | 1995-03-15 | ||
| JP22720595 | 1995-08-12 | ||
| PCT/JP1995/001936 WO1996010019A1 (en) | 1994-09-26 | 1995-09-25 | Imidazole derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE255564T1 true ATE255564T1 (de) | 2003-12-15 |
Family
ID=27304632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95932231T ATE255564T1 (de) | 1994-09-26 | 1995-09-25 | Imidazolderivat |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5910506A (de) |
| EP (1) | EP0786455B1 (de) |
| JP (1) | JP3155009B2 (de) |
| KR (1) | KR100387157B1 (de) |
| CN (1) | CN1093535C (de) |
| AT (1) | ATE255564T1 (de) |
| BR (1) | BR9509024A (de) |
| CA (1) | CA2200316C (de) |
| DE (1) | DE69532245T2 (de) |
| DK (1) | DK0786455T3 (de) |
| ES (1) | ES2211917T3 (de) |
| FI (1) | FI971234A7 (de) |
| HU (1) | HUT77357A (de) |
| MX (1) | MX9702030A (de) |
| NO (1) | NO308739B1 (de) |
| PL (1) | PL183931B1 (de) |
| PT (1) | PT786455E (de) |
| RU (1) | RU2157368C2 (de) |
| TW (1) | TW401404B (de) |
| WO (1) | WO1996010019A1 (de) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6054591A (en) * | 1996-03-28 | 2000-04-25 | Shionogi & Co., Ltd. | Lymph-absorbable aryl substituted imidazole derivatives |
| MXPA98008158A (es) * | 1996-04-04 | 2002-02-08 | Shionogi & Co | Composicion anti-vih que contiene derivados de imidazol. |
| RU2188638C2 (ru) * | 1996-04-04 | 2002-09-10 | Шионоги Энд Ко., Лтд. | Анти-вич-композиция, содержащая имидазольные производные |
| DE69728180T2 (de) * | 1996-12-26 | 2005-03-17 | Shionogi & Co., Ltd. | Verfahren zur herstellung von carbamoylsubstituierten imidazolderivaten |
| EP0949249B1 (de) * | 1996-12-26 | 2005-07-13 | Shionogi & Co., Ltd. | Verfahren zur herstellung von imidazolderivaten |
| TWI232214B (en) | 1998-04-16 | 2005-05-11 | Shionogi & Co | Preparation of aryl sulfenyl halide |
| WO2000061109A1 (fr) | 1999-04-12 | 2000-10-19 | Shionogi & Co., Ltd. | Procede de production de composition medicamenteuse renfermant un compose medicamenteux hydrophobe basique |
| GB0016787D0 (en) * | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
| PL363321A1 (en) | 2001-01-31 | 2004-11-15 | Warner-Lambert Company Llc | Method for carbamoylating alcohols |
| DK1370539T3 (da) | 2001-02-23 | 2012-02-13 | Leuven K U Res & Dev | HIV-inhiberende N-aminoimidazolderivater |
| SI1762567T1 (sl) | 2001-04-10 | 2012-08-31 | Pfizer | Derivati pirazola za zdravljenje HIV-a |
| GB0113524D0 (en) * | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
| FR2825926A1 (fr) * | 2001-06-14 | 2002-12-20 | Sod Conseils Rech Applic | Derives d'imidazoles modulant les canaux sodiques |
| EP1501817A1 (de) * | 2002-04-23 | 2005-02-02 | F. Hoffmann-La Roche Ag | Imidazolinylmethyl aralkylsulfonamide |
| TW200408645A (en) | 2002-04-26 | 2004-06-01 | Gilead Sciences Inc | Non nucleoside reverse transcriptase inhibitors |
| TW200423930A (en) | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
| WO2004085406A1 (en) | 2003-03-24 | 2004-10-07 | F. Hoffmann-La Roche Ag | Benzyl-pyridazinons as reverse transcriptase inhibitors |
| US7452901B2 (en) | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
| EP1620109A2 (de) | 2003-04-25 | 2006-02-01 | Gilead Sciences, Inc. | Kinase inhbitor phosphonat konjugate |
| US7470724B2 (en) | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
| US7427636B2 (en) | 2003-04-25 | 2008-09-23 | Gilead Sciences, Inc. | Inosine monophosphate dehydrogenase inhibitory phosphonate compounds |
| US7432261B2 (en) | 2003-04-25 | 2008-10-07 | Gilead Sciences, Inc. | Anti-inflammatory phosphonate compounds |
| WO2004096285A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Anti-infective phosphonate conjugates |
| US7407965B2 (en) | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
| SG182849A1 (en) | 2003-04-25 | 2012-08-30 | Gilead Sciences Inc | Antiviral phosphonate analogs |
| WO2005002626A2 (en) | 2003-04-25 | 2005-01-13 | Gilead Sciences, Inc. | Therapeutic phosphonate compounds |
| WO2005016912A1 (en) * | 2003-08-19 | 2005-02-24 | Pfizer Inc. | An efficient microbial preparation of capravirine metabolites m4 and m5 |
| US7432273B2 (en) | 2003-10-24 | 2008-10-07 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
| WO2005042773A1 (en) | 2003-10-24 | 2005-05-12 | Gilead Sciences, Inc. | Methods and compositions for identifying therapeutic compounds |
| WO2005044279A1 (en) | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Purine nucleoside phosphonate conjugates |
| CA2548388A1 (en) * | 2003-12-15 | 2005-06-30 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| BRPI0417988A (pt) | 2003-12-22 | 2007-04-27 | Gilead Sciences Inc | análogos de fosfonato antivirais |
| EP1740550A1 (de) * | 2004-04-14 | 2007-01-10 | Pfizer Limited | Schwefelgebundene imidazolverbindungen zur behandlung von hiv |
| KR100749566B1 (ko) * | 2004-04-21 | 2007-08-16 | 이화여자대학교 산학협력단 | Alk5 및/또는 alk4 억제제로 유효한 2-피리딜이치환된 이미다졸 유도체 |
| US7893278B2 (en) * | 2004-06-17 | 2011-02-22 | Hoffman-La Roche Inc. | CIS-imidazolines |
| PT2258376T (pt) | 2004-07-27 | 2019-05-31 | Gilead Sciences Inc | Análogos fosfonatados de compostos inibidores do vih |
| JP4993407B2 (ja) | 2004-08-04 | 2012-08-08 | 大正製薬株式会社 | トリアゾール誘導体 |
| CA2592909A1 (en) * | 2005-01-06 | 2006-07-13 | Pfizer Limited | Imidazole derivatives as enzyme reverse transcriptase modulators |
| KR101139263B1 (ko) * | 2005-03-16 | 2012-05-16 | 에프. 호프만-라 로슈 아게 | 시스-2,4,5-트리아릴-이미다졸린 및 항암 약제로서의그의 용도 |
| CN101316823B (zh) * | 2005-12-01 | 2013-05-22 | 霍夫曼-拉罗奇有限公司 | 用作抗癌剂的作为p53和MDM2蛋白之间相互作用的抑制剂的2,4,5-三苯基咪唑啉衍生物 |
| PL1988083T3 (pl) | 2006-02-03 | 2014-08-29 | Taisho Pharmaceutical Co Ltd | Pochodna triazolowa |
| RU2395499C2 (ru) * | 2006-02-06 | 2010-07-27 | Тайсо Фармасьютикал Ко., Лтд. | Ингибитор связывания сфингозин-1-фосфата |
| US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
| US7994205B2 (en) * | 2006-03-31 | 2011-08-09 | Takeda Pharmaceutical Company Limited | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors |
| PE20080948A1 (es) * | 2006-07-25 | 2008-09-10 | Irm Llc | Derivados de imidazol como moduladores de la senda de hedgehog |
| DE602007013573D1 (de) | 2006-08-16 | 2011-05-12 | Hoffmann La Roche | Nicht-nukleosidische reverse-transkriptase-hemmer |
| ATE554070T1 (de) | 2007-08-01 | 2012-05-15 | Taisho Pharmaceutical Co Ltd | Hemmer der s1p1-bindung |
| TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
| JP5345140B2 (ja) * | 2007-09-28 | 2013-11-20 | 武田薬品工業株式会社 | プロトンポンプ阻害剤としての5員複素環化合物 |
| AU2008340422B2 (en) | 2007-12-21 | 2014-06-19 | F. Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
| BRPI0915878A2 (pt) | 2008-07-08 | 2015-11-03 | Gilead Sciences Inc | sais ou hidratos de compostos inibidores de hiv, seu uso e composição farmacêutica que os compreende |
| JP2012517479A (ja) * | 2009-02-12 | 2012-08-02 | エグゼリクシス, インコーポレイテッド | 糖尿病および肥満の処置においてtgr5アゴニストとして使用するためのトリアゾールおよびイミダゾール誘導体 |
| WO2010110378A1 (ja) | 2009-03-26 | 2010-09-30 | 武田薬品工業株式会社 | ピラゾール化合物 |
| EP2508511A1 (de) * | 2011-04-07 | 2012-10-10 | Laboratoire Biodim | Inhibitoren der Virenreplikation, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
| CA2879726A1 (en) * | 2012-07-24 | 2014-01-30 | Bial- Portela & Ca, S.A. | Urea compounds and their use as enzyme inhibitors |
| EP2716632A1 (de) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitoren der Virenreplikation, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
| EP2716639A1 (de) | 2012-10-05 | 2014-04-09 | Laboratoire Biodim | Inhibitoren der Virenreplikation, Verfahren zu deren Herstellung und deren therapeutische Verwendung |
| GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
| EP3381905A1 (de) * | 2017-03-30 | 2018-10-03 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Neuartige antivirale verbindungen |
| PT3661937T (pt) | 2017-08-01 | 2021-09-24 | Gilead Sciences Inc | Formas cristalinas de ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-il)-4-fluoro-2,5-dihidrofurano-2-il)oxi)metil)(fenoxi)fosforil)-l-alaninato de etil (gs-9131) para tratamento de infeções virais |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
| JPS63150266A (ja) * | 1986-12-12 | 1988-06-22 | Mitsui Petrochem Ind Ltd | ベンジルイミダゾ−ル誘導体 |
| JPH0283373A (ja) * | 1988-05-19 | 1990-03-23 | Nippon Soda Co Ltd | 5員環の複素環化合物及びその製造方法 |
| IL98319A (en) * | 1990-07-05 | 1997-04-15 | Roussel Uclaf | Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them |
| TW235963B (de) * | 1992-01-16 | 1994-12-11 | Shionogi & Co | |
| DE10230797C2 (de) * | 2001-07-16 | 2003-09-25 | Dieter Reif | Befestigungsklammer zur Verbindung von Holzbauteilen |
-
1995
- 1995-09-25 BR BR9509024A patent/BR9509024A/pt not_active IP Right Cessation
- 1995-09-25 AT AT95932231T patent/ATE255564T1/de not_active IP Right Cessation
- 1995-09-25 WO PCT/JP1995/001936 patent/WO1996010019A1/ja not_active Ceased
- 1995-09-25 KR KR1019970701989A patent/KR100387157B1/ko not_active Expired - Fee Related
- 1995-09-25 EP EP95932231A patent/EP0786455B1/de not_active Expired - Lifetime
- 1995-09-25 RU RU97106829/04A patent/RU2157368C2/ru not_active IP Right Cessation
- 1995-09-25 CA CA002200316A patent/CA2200316C/en not_active Expired - Fee Related
- 1995-09-25 MX MX9702030A patent/MX9702030A/es not_active IP Right Cessation
- 1995-09-25 FI FI971234A patent/FI971234A7/fi unknown
- 1995-09-25 DK DK95932231T patent/DK0786455T3/da active
- 1995-09-25 PT PT95932231T patent/PT786455E/pt unknown
- 1995-09-25 US US08/809,624 patent/US5910506A/en not_active Expired - Fee Related
- 1995-09-25 ES ES95932231T patent/ES2211917T3/es not_active Expired - Lifetime
- 1995-09-25 CN CN95195260A patent/CN1093535C/zh not_active Expired - Fee Related
- 1995-09-25 HU HU9701899A patent/HUT77357A/hu not_active Application Discontinuation
- 1995-09-25 JP JP51159896A patent/JP3155009B2/ja not_active Expired - Fee Related
- 1995-09-25 DE DE69532245T patent/DE69532245T2/de not_active Expired - Fee Related
- 1995-09-25 PL PL95320009A patent/PL183931B1/pl not_active IP Right Cessation
- 1995-09-29 TW TW084110183A patent/TW401404B/zh not_active IP Right Cessation
-
1997
- 1997-03-20 NO NO971306A patent/NO308739B1/no unknown
-
1998
- 1998-12-04 US US09/205,289 patent/US6147097A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0786455A4 (de) | 1998-12-30 |
| CA2200316C (en) | 2004-09-21 |
| EP0786455A1 (de) | 1997-07-30 |
| TW401404B (en) | 2000-08-11 |
| PL183931B1 (pl) | 2002-08-30 |
| RU2157368C2 (ru) | 2000-10-10 |
| CN1158609A (zh) | 1997-09-03 |
| DE69532245D1 (en) | 2004-01-15 |
| BR9509024A (pt) | 1997-09-30 |
| US6147097A (en) | 2000-11-14 |
| KR970706260A (ko) | 1997-11-03 |
| PL320009A1 (en) | 1997-09-01 |
| JP3155009B2 (ja) | 2001-04-09 |
| NO971306L (no) | 1997-05-21 |
| FI971234L (fi) | 1997-05-23 |
| PT786455E (pt) | 2004-02-27 |
| FI971234A0 (fi) | 1997-03-25 |
| CA2200316A1 (en) | 1996-04-04 |
| NO971306D0 (no) | 1997-03-20 |
| HUT77357A (hu) | 1998-03-30 |
| US5910506A (en) | 1999-06-08 |
| AU4788896A (en) | 1996-04-19 |
| WO1996010019A1 (en) | 1996-04-04 |
| DK0786455T3 (da) | 2004-03-29 |
| FI971234A7 (fi) | 1997-05-23 |
| CN1093535C (zh) | 2002-10-30 |
| ES2211917T3 (es) | 2004-07-16 |
| NO308739B1 (no) | 2000-10-23 |
| EP0786455B1 (de) | 2003-12-03 |
| DE69532245T2 (de) | 2004-09-16 |
| AU706095B2 (en) | 1999-06-10 |
| MX9702030A (es) | 1997-06-28 |
| KR100387157B1 (ko) | 2003-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0786455T3 (da) | Imidazolderivater | |
| NO179142C (no) | 3-benzyliden-1-karbamoyl-2-pyrrolidon-analoger | |
| EP0742216A3 (de) | Ringamide-Derivate | |
| ID29452A (id) | 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus | |
| NO974912L (no) | Pentacykliske forbindelser | |
| PT732928E (pt) | Metodo para a reducao dos niveis de colesterol serico com 2,6-dialquil-4-sililfenois | |
| ATE144530T1 (de) | Glutathionderivat | |
| ATE113030T1 (de) | Hydroxyalkancarbonsäure-derivate und deren verwendung. | |
| ATE176906T1 (de) | Benzolactam-derivate | |
| DK0601191T3 (da) | Hidtil ukendt tetracyklisk forbindelse | |
| DK0594329T3 (da) | Antimikrobielle midler, der omfatter polykvaternære ammoniumforbindelser | |
| EP0676399A4 (de) | Methotrexat-derivate. | |
| ATE318265T1 (de) | Amidin-derivate, ihre herstellung und verwendung als medikamenten | |
| ATE284379T1 (de) | Aminderivate | |
| BR9305092A (pt) | Processo para a preparação de derivados de 5-pirazolmercáptan, composto ditiocarbazato de etilideno, processo para a preparação de derivados do mesmo | |
| ES2077697T3 (es) | Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0786455 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |