ATE456564T1 - Octahydrobenzimidazolon-verbindungen als analgetika - Google Patents

Octahydrobenzimidazolon-verbindungen als analgetika

Info

Publication number: ATE456564T1
Authority: AT; Austria
Prior art keywords: compounds; octahydrobenzimidazolone; analgesics; analgetics; formula
Prior art date: 2001-04-18

Application number

AT08011371T

Other languages

English (en)

Inventor

Richard R Goehring

Zhengming Chen

Donald Kyle

Sam Victory

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-18

Filing date

2002-04-18

Publication date

2010-02-15

2002-04-18 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE456564T1 publication Critical patent/ATE456564T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
229940035676 analgesics Drugs 0.000 title 1
239000000730 antalgic agent Substances 0.000 title 1
230000000202 analgesic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychiatry (AREA)
Hematology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT08011371T 2001-04-18 2002-04-18 Octahydrobenzimidazolon-verbindungen als analgetika ATE456564T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28466501P	2001-04-18	2001-04-18

Publications (1)

Publication Number	Publication Date
ATE456564T1 true ATE456564T1 (de)	2010-02-15

Family

ID=23091051

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT08011371T ATE456564T1 (de)	2001-04-18	2002-04-18	Octahydrobenzimidazolon-verbindungen als analgetika
AT02764243T ATE403431T1 (de)	2001-04-18	2002-04-18	Benzimidazolon-verbindungen

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02764243T ATE403431T1 (de)	2001-04-18	2002-04-18	Benzimidazolon-verbindungen

Country Status (13)

Country	Link
US (2)	US6872733B2 (de)
EP (3)	EP2172468A1 (de)
JP (1)	JP4401076B2 (de)
AT (2)	ATE456564T1 (de)
AU (1)	AU2002338424B2 (de)
CA (1)	CA2444489C (de)
CY (2)	CY1108456T1 (de)
DE (2)	DE60235274D1 (de)
DK (2)	DK1975164T3 (de)
ES (2)	ES2312616T3 (de)
PT (2)	PT1975164E (de)
SI (2)	SI1385518T1 (de)
WO (1)	WO2002085361A1 (de)

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DK1491212T3 (da)	2002-03-29	2012-10-29	Mitsubishi Tanabe Pharma Corp	Middel til behandling af søvnforstyrrelser
US20110008327A1 (en)	2004-03-29	2011-01-13	Cheng Jin Q	Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100028339A1 (en)	2004-03-29	2010-02-04	Cheng Jin Q	Compositions including triciribine and trastuzumab and methods of use thereof
US20100009929A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100173864A1 (en)	2004-03-29	2010-07-08	Cheng Jin Q	Compositions including triciribine and one or more platinum compounds and methods of use thereof
US20100009928A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and taxanes and methods of use thereof
EP2574341B1 (de)	2004-03-29	2017-03-29	University Of South Florida	Wirksame Behandlung von Tumoren und Krebs mit Triciribin-Phosphat
EA016286B1 (ru) *	2005-09-30	2012-03-30	Глэксо Груп Лимитед	Соединения, которые обладают активностью по отношению к рецепторам м, и их применения в медицине
JP5209481B2 (ja) *	2005-09-30	2013-06-12	グラクソグループリミテッド	Ｍ１受容体にて活性を有する化合物および医薬におけるそれらの使用
JP5209479B2 (ja) *	2005-09-30	2013-06-12	グラクソグループリミテッド	Ｍ１受容体にて活性を有するベンゾイミダゾロン類
CN1870631B (zh) *	2005-11-11	2010-04-14	华为技术有限公司	媒体网关的门控方法
TW200813018A (en) *	2006-06-09	2008-03-16	Astrazeneca Ab	Novel compounds
US20080051380A1 (en)	2006-08-25	2008-02-28	Auerbach Alan H	Methods and compositions for treating cancer
JP5462633B2 (ja)	2007-01-16	2014-04-02	パーデュー、ファーマ、リミテッド、パートナーシップ	複素環置換ピペリジン化合物とその使用
GB0706188D0 (en) *	2007-03-29	2007-05-09	Glaxo Group Ltd	Compounds
JP5554709B2 (ja) *	2007-08-31	2014-07-23	パーデュー、ファーマ、リミテッド、パートナーシップ	置換キノキサリンタイプピペリジン化合物とその使用
US8119661B2 (en)	2007-09-11	2012-02-21	Astrazeneca Ab	Piperidine derivatives and their use as muscarinic receptor modulators
GB0718415D0 (en) *	2007-09-20	2007-10-31	Glaxo Group Ltd	Compounds
ES2393849T7 (es)	2008-07-21	2015-01-28	Purdue Pharma Lp	Compuestos de piperidina puenteada, de tipo quinoxalina sustituida, y usos de los mismos
US10118927B2 (en)	2012-12-27	2018-11-06	Purdue Pharma L.P.	Substituted piperidin-4-amino-type compounds and uses thereof
US9951038B2 (en)	2012-12-27	2018-04-24	Purdue Pharma L.P.	Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
WO2014102594A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102588A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Indole and indoline-type piperidine compounds and uses thereof
MX2019001224A (es)	2016-07-29	2019-06-03	Janssen Pharmaceutica Nv	Metodos para tratar el cancer de prostata.

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2002
- 2002-04-18 WO PCT/US2002/012375 patent/WO2002085361A1/en not_active Ceased
- 2002-04-18 DE DE60235274T patent/DE60235274D1/de not_active Expired - Lifetime
- 2002-04-18 DK DK08011371.5T patent/DK1975164T3/da active
- 2002-04-18 SI SI200230749T patent/SI1385518T1/sl unknown
- 2002-04-18 EP EP10000601A patent/EP2172468A1/de not_active Withdrawn
- 2002-04-18 PT PT08011371T patent/PT1975164E/pt unknown
- 2002-04-18 EP EP08011371A patent/EP1975164B1/de not_active Expired - Lifetime
- 2002-04-18 SI SI200230894T patent/SI1975164T1/sl unknown
- 2002-04-18 EP EP02764243A patent/EP1385518B1/de not_active Expired - Lifetime
- 2002-04-18 ES ES02764243T patent/ES2312616T3/es not_active Expired - Lifetime
- 2002-04-18 AU AU2002338424A patent/AU2002338424B2/en not_active Ceased
- 2002-04-18 CA CA2444489A patent/CA2444489C/en not_active Expired - Fee Related
- 2002-04-18 PT PT02764243T patent/PT1385518E/pt unknown
- 2002-04-18 DE DE60228072T patent/DE60228072D1/de not_active Expired - Lifetime
- 2002-04-18 ES ES08011371T patent/ES2340441T3/es not_active Expired - Lifetime
- 2002-04-18 AT AT08011371T patent/ATE456564T1/de not_active IP Right Cessation
- 2002-04-18 AT AT02764243T patent/ATE403431T1/de not_active IP Right Cessation
- 2002-04-18 JP JP2002582934A patent/JP4401076B2/ja not_active Expired - Fee Related
- 2002-04-18 US US10/126,437 patent/US6872733B2/en not_active Expired - Lifetime
- 2002-04-18 DK DK02764243T patent/DK1385518T3/da active
2005
- 2005-03-28 US US11/091,229 patent/US20050192307A1/en not_active Abandoned
2008
- 2008-10-27 CY CY20081101210T patent/CY1108456T1/el unknown
2010
- 2010-04-14 CY CY20101100336T patent/CY1110000T1/el unknown

Also Published As

Publication number	Publication date
ATE403431T1 (de)	2008-08-15
US20030008886A1 (en)	2003-01-09
US6872733B2 (en)	2005-03-29
EP1385518B1 (de)	2008-08-06
EP1975164A2 (de)	2008-10-01
CY1110000T1 (el)	2012-05-23
CA2444489C (en)	2010-06-22
SI1385518T1 (sl)	2009-02-28
US20050192307A1 (en)	2005-09-01
EP2172468A1 (de)	2010-04-07
DE60235274D1 (de)	2010-03-18
DK1385518T3 (da)	2008-10-27
AU2002338424B2 (en)	2005-04-21
DK1975164T3 (da)	2010-05-25
SI1975164T1 (sl)	2010-05-31
EP1385518A4 (de)	2005-10-05
JP4401076B2 (ja)	2010-01-20
EP1975164B1 (de)	2010-01-27
EP1975164A3 (de)	2008-10-08
CY1108456T1 (el)	2012-05-23
JP2004531532A (ja)	2004-10-14
ES2312616T3 (es)	2009-03-01
EP1385518A1 (de)	2004-02-04
ES2340441T3 (es)	2010-06-02
PT1385518E (pt)	2008-10-07
CA2444489A1 (en)	2002-10-31
DE60228072D1 (de)	2008-09-18
PT1975164E (pt)	2010-04-20
WO2002085361A1 (en)	2002-10-31

Legal Events

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2010-07-15

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Publication of translation of european patent specification

Ref document number: 1975164

Country of ref document: EP

2012-01-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE456564T1 (de)	2010-02-15	Octahydrobenzimidazolon-verbindungen als analgetika
DE60229736D1 (de)	2008-12-18	Spiroinden- und spiroindan-verbindungen
ATE404528T1 (de)	2008-08-15	7,9 substituierte tetracyclinverbindungen
ES2172864T3 (es)	2002-10-01	2-metoxibenzofenonas fungicidas.
IL159418A0 (en)	2004-06-01	Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
DE60214392D1 (de)	2006-10-12	1,4-disubstituierte benzokondensierte cycloalkyl harnstoffverbindungen
DK1385515T3 (da)	2008-10-27	Spiropyrazole forbindelser
NO20024766D0 (no)	2002-10-03	Etyldiaminderivater
DE60232289D1 (de)	2009-06-25	Photopolymerisierbare Verbindungen
DE60039695D1 (de)	2008-09-11	Antifucoidan antikörper
EP1557407A4 (de)	2006-11-15	Neue alpha-ketoamidderivate und deren verwendung
ES2200689B1 (es)	2005-05-01	Compuestos de pirona y su uso.
BR0101556A (pt)	2003-03-25	Composto heterocìclico
TH42384A (th)	2001-01-10	อนุพันธ์ d-โปรไลน์