ATE456564T1 - Octahydrobenzimidazolon-verbindungen als analgetika - Google Patents

Octahydrobenzimidazolon-verbindungen als analgetika

Info

Publication number: ATE456564T1
Authority: AT; Austria
Prior art keywords: compounds; octahydrobenzimidazolone; analgesics; analgetics; formula
Prior art date: 2001-04-18

Application number

AT08011371T

Other languages

English (en)

Inventor

Richard R Goehring

Zhengming Chen

Donald Kyle

Sam Victory

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-18

Filing date

2002-04-18

Publication date

2010-02-15

2002-04-18 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE456564T1 publication Critical patent/ATE456564T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
229940035676 analgesics Drugs 0.000 title 1
239000000730 antalgic agent Substances 0.000 title 1
230000000202 analgesic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT08011371T 2001-04-18 2002-04-18 Octahydrobenzimidazolon-verbindungen als analgetika ATE456564T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28466501P	2001-04-18	2001-04-18

Publications (1)

Publication Number	Publication Date
ATE456564T1 true ATE456564T1 (de)	2010-02-15

Family

ID=23091051

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT02764243T ATE403431T1 (de)	2001-04-18	2002-04-18	Benzimidazolon-verbindungen
AT08011371T ATE456564T1 (de)	2001-04-18	2002-04-18	Octahydrobenzimidazolon-verbindungen als analgetika

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT02764243T ATE403431T1 (de)	2001-04-18	2002-04-18	Benzimidazolon-verbindungen

Country Status (13)

Country	Link
US (2)	US6872733B2 (de)
EP (3)	EP1385518B1 (de)
JP (1)	JP4401076B2 (de)
AT (2)	ATE403431T1 (de)
AU (1)	AU2002338424B2 (de)
CA (1)	CA2444489C (de)
CY (2)	CY1108456T1 (de)
DE (2)	DE60235274D1 (de)
DK (2)	DK1385518T3 (de)
ES (2)	ES2340441T3 (de)
PT (2)	PT1385518E (de)
SI (2)	SI1385518T1 (de)
WO (1)	WO2002085361A1 (de)

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US20110008327A1 (en)	2004-03-29	2011-01-13	Cheng Jin Q	Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100028339A1 (en)	2004-03-29	2010-02-04	Cheng Jin Q	Compositions including triciribine and trastuzumab and methods of use thereof
US20100009928A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and taxanes and methods of use thereof
US20100009929A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
MXPA06011219A (es)	2004-03-29	2007-05-08	Univ South Florida	Tratamiento efectivo de tumores y cancer con triciribina y compuestos relacionados.
US20100173864A1 (en)	2004-03-29	2010-07-08	Cheng Jin Q	Compositions including triciribine and one or more platinum compounds and methods of use thereof
WO2007036711A1 (en) *	2005-09-30	2007-04-05	Glaxo Group Limited	BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT Ml RECEPTOR
US8283364B2 (en) *	2005-09-30	2012-10-09	Glaxo Group Limited	Compounds which have activity at M1 receptor and their uses in medicine
WO2007036718A2 (en) *	2005-09-30	2007-04-05	Glaxo Group Limited	Compounds which have activity at m1 receptor and their uses in medicine
CN1870631B (zh) *	2005-11-11	2010-04-14	华为技术有限公司	媒体网关的门控方法
TW200813018A (en) *	2006-06-09	2008-03-16	Astrazeneca Ab	Novel compounds
US20080051380A1 (en)	2006-08-25	2008-02-28	Auerbach Alan H	Methods and compositions for treating cancer
EP2397477B1 (de) *	2007-01-16	2014-03-05	Purdue Pharma LP	Heterocyclisch-substituierte Piperidinverbindungen und Verwendungen davon
GB0706188D0 (en) *	2007-03-29	2007-05-09	Glaxo Group Ltd	Compounds
MY150602A (en) *	2007-08-31	2014-01-30	Purdue Pharma Lp	Subtituted-quinoxaline-type piperidine compounds and the uses thereof
US8119661B2 (en)	2007-09-11	2012-02-21	Astrazeneca Ab	Piperidine derivatives and their use as muscarinic receptor modulators
GB0718415D0 (en) *	2007-09-20	2007-10-31	Glaxo Group Ltd	Compounds
KR101333660B1 (ko)	2008-07-21	2013-11-27	시오노기세이야쿠가부시키가이샤	치환-퀴녹살린-형 가교-피페리딘 화합물 및 그의 용도
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WO2014102588A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Indole and indoline-type piperidine compounds and uses thereof
WO2014102594A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Substituted benzimidazole-type piperidine compounds and uses thereof
US10118927B2 (en)	2012-12-27	2018-11-06	Purdue Pharma L.P.	Substituted piperidin-4-amino-type compounds and uses thereof
UA124972C2 (uk)	2016-07-29	2021-12-22	Янссен Фармацевтика Нв	Способи лікування раку передміхурової залози

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2002
- 2002-04-18 EP EP02764243A patent/EP1385518B1/de not_active Expired - Lifetime
- 2002-04-18 ES ES08011371T patent/ES2340441T3/es not_active Expired - Lifetime
- 2002-04-18 SI SI200230749T patent/SI1385518T1/sl unknown
- 2002-04-18 DK DK02764243T patent/DK1385518T3/da active
- 2002-04-18 EP EP10000601A patent/EP2172468A1/de not_active Withdrawn
- 2002-04-18 ES ES02764243T patent/ES2312616T3/es not_active Expired - Lifetime
- 2002-04-18 US US10/126,437 patent/US6872733B2/en not_active Expired - Lifetime
- 2002-04-18 DE DE60235274T patent/DE60235274D1/de not_active Expired - Lifetime
- 2002-04-18 JP JP2002582934A patent/JP4401076B2/ja not_active Expired - Fee Related
- 2002-04-18 WO PCT/US2002/012375 patent/WO2002085361A1/en not_active Ceased
- 2002-04-18 CA CA2444489A patent/CA2444489C/en not_active Expired - Fee Related
- 2002-04-18 PT PT02764243T patent/PT1385518E/pt unknown
- 2002-04-18 AT AT02764243T patent/ATE403431T1/de not_active IP Right Cessation
- 2002-04-18 PT PT08011371T patent/PT1975164E/pt unknown
- 2002-04-18 DK DK08011371.5T patent/DK1975164T3/da active
- 2002-04-18 AT AT08011371T patent/ATE456564T1/de not_active IP Right Cessation
- 2002-04-18 SI SI200230894T patent/SI1975164T1/sl unknown
- 2002-04-18 EP EP08011371A patent/EP1975164B1/de not_active Expired - Lifetime
- 2002-04-18 DE DE60228072T patent/DE60228072D1/de not_active Expired - Lifetime
- 2002-04-18 AU AU2002338424A patent/AU2002338424B2/en not_active Ceased
2005
- 2005-03-28 US US11/091,229 patent/US20050192307A1/en not_active Abandoned
2008
- 2008-10-27 CY CY20081101210T patent/CY1108456T1/el unknown
2010
- 2010-04-14 CY CY20101100336T patent/CY1110000T1/el unknown

Also Published As

Publication number	Publication date
SI1975164T1 (sl)	2010-05-31
EP1975164A3 (de)	2008-10-08
DE60228072D1 (de)	2008-09-18
CY1108456T1 (el)	2012-05-23
EP1975164B1 (de)	2010-01-27
JP2004531532A (ja)	2004-10-14
PT1385518E (pt)	2008-10-07
US6872733B2 (en)	2005-03-29
CY1110000T1 (el)	2012-05-23
US20030008886A1 (en)	2003-01-09
EP2172468A1 (de)	2010-04-07
DE60235274D1 (de)	2010-03-18
AU2002338424B2 (en)	2005-04-21
EP1385518A4 (de)	2005-10-05
US20050192307A1 (en)	2005-09-01
PT1975164E (pt)	2010-04-20
CA2444489A1 (en)	2002-10-31
ATE403431T1 (de)	2008-08-15
WO2002085361A1 (en)	2002-10-31
EP1385518B1 (de)	2008-08-06
DK1975164T3 (da)	2010-05-25
JP4401076B2 (ja)	2010-01-20
ES2312616T3 (es)	2009-03-01
ES2340441T3 (es)	2010-06-02
DK1385518T3 (da)	2008-10-27
EP1385518A1 (de)	2004-02-04
SI1385518T1 (sl)	2009-02-28
EP1975164A2 (de)	2008-10-01
CA2444489C (en)	2010-06-22

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2010-07-15

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2012-01-15

REN

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Publication	Publication Date	Title
DE60235274D1 (de)	2010-03-18	Octahydrobenzimidazolon-Verbindungen als Analgetika
DK1385514T5 (da)	2009-03-09	Spiroinden- og spiroindanforbindelser
ATE404528T1 (de)	2008-08-15	7,9 substituierte tetracyclinverbindungen
DE69803907D1 (de)	2002-03-28	Fungizide 2-Methoxybenzophenone
ZA200309887B (en)	2004-07-20	Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents.
DE60214392D1 (de)	2006-10-12	1,4-disubstituierte benzokondensierte cycloalkyl harnstoffverbindungen
DK1385515T3 (da)	2008-10-27	Spiropyrazole forbindelser
NO20024766D0 (no)	2002-10-03	Etyldiaminderivater
ATE431328T1 (de)	2009-05-15	Photopolymerisierbare verbindungen
DE60039695D1 (de)	2008-09-11	Antifucoidan antikörper
EP1557407A4 (de)	2006-11-15	Neue alpha-ketoamidderivate und deren verwendung
ES2200689B1 (es)	2005-05-01	Compuestos de pirona y su uso.
BR0101556A (pt)	2003-03-25	Composto heterocìclico