ATE255589T1 - Kristallin form i von clarithromycin - Google Patents

Kristallin form i von clarithromycin

Info

Publication number: ATE255589T1
Authority: AT; Austria
Prior art keywords: clarithromycin; crystalline form; methylerythromycin; antiobiotic; novel
Prior art date: 1996-07-29

Application number

AT97934307T

Other languages

English (en)

Inventor

Jih-Hua Liu

David A Riley

Stephen G Spanton

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-29

Filing date

1997-07-25

Publication date

2003-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24736505&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE255589(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-07-25 Application filed by Abbott Lab filed Critical Abbott Lab

2003-12-15 Application granted granted Critical

2003-12-15 Publication of ATE255589T1 publication Critical patent/ATE255589T1/de

Links

AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 2
229960002626 clarithromycin Drugs 0.000 title abstract 2
238000000034 method Methods 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
239000013078 crystal Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT97934307T 1996-07-29 1997-07-25 Kristallin form i von clarithromycin ATE255589T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/681,723 US5858986A (en)	1996-07-29	1996-07-29	Crystal form I of clarithromycin
PCT/US1997/013128 WO1998004573A1 (en)	1996-07-29	1997-07-25	Crystal form i of clarithromycin

Publications (1)

Publication Number	Publication Date
ATE255589T1 true ATE255589T1 (de)	2003-12-15

Family

ID=24736505

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97934307T ATE255589T1 (de)	1996-07-29	1997-07-25	Kristallin form i von clarithromycin

Country Status (18)

Country	Link
US (1)	US5858986A (de)
EP (1)	EP0915898B1 (de)
JP (2)	JP2000515894A (de)
KR (1)	KR100498800B1 (de)
CN (2)	CN1216892C (de)
AT (1)	ATE255589T1 (de)
AU (1)	AU3739797A (de)
BR (1)	BR9710768A (de)
CA (2)	CA2258606C (de)
CZ (1)	CZ294446B6 (de)
DE (1)	DE69726577T2 (de)
DK (1)	DK0915898T3 (de)
ES (1)	ES2173056T3 (de)
IL (1)	IL127581A (de)
NZ (1)	NZ333380A (de)
PT (1)	PT915898E (de)
TR (1)	TR199900083T2 (de)
WO (1)	WO1998004573A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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US5945405A (en) *	1997-01-17	1999-08-31	Abbott Laboratories	Crystal form O of clarithromycin
KR100377159B1 (ko) *	1998-09-09	2003-08-19	한미약품공업 주식회사	잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법
GB9827355D0 (en) *	1998-12-11	1999-02-03	Biochemie Sa	Organic compounds
AU4942800A (en) *	1999-06-11	2001-01-02	Ranbaxy Laboratories Limited	Novel amorphous form of clarithromycin
KR100336447B1 (ko) *	1999-11-24	2002-05-15	민경윤	클라리스로마이신의 개선된 제조방법
US6627743B1 (en)	1999-12-03	2003-09-30	Abbott Laboratories	6-O-methylerythromycin A crystal form III
AU783055B2 (en) *	1999-12-16	2005-09-22	Teva Pharmaceutical Industries Ltd.	Processes for preparing clarithromycin polymorphs and novel polymorph IV
RU2002118308A (ru)	2000-01-11	2004-02-20	Тева Фамэситикл Индастрис Лтд. (Il)	Способы получения полиморфных модификаций кларитромицина
US6544555B2 (en) *	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
US6565882B2 (en) *	2000-02-24	2003-05-20	Advancis Pharmaceutical Corp	Antibiotic composition with inhibitor
HUP0302466A2 (hu) *	2000-02-29	2003-11-28	Teva Pharmaceutical Industries Ltd.	Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
ATE297941T1 (de) *	2000-03-15	2005-07-15	Hanmi Pharm Ind Co Ltd	Verfahren zur herstellung von einer kristallinen form ii von clarythromycin
BR0109544A (pt) *	2000-03-28	2003-06-10	Biochemie Gmbh	Partìculas granuladas com sabor ocultado
KR20000037126A (ko) *	2000-04-08	2000-07-05	김용규	6-메틸 에리스로마이신 ａ의 제조방법
US6541014B2 (en) *	2000-10-13	2003-04-01	Advancis Pharmaceutical Corp.	Antiviral product, use and formulation thereof
MXPA03003146A (es) *	2000-10-13	2004-12-06	Advancis Pharmaceuticals	Derivados de eritromicina de liberacion prolongada.
US20020068078A1 (en) *	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
US20020197314A1 (en) *	2001-02-23	2002-12-26	Rudnic Edward M.	Anti-fungal composition
KR100408848B1 (ko) *	2001-03-12	2003-12-06	주식회사 씨트리	클래리스로마이신의 정제방법
CN100427498C (zh) *	2003-03-02	2008-10-22	王凌峰	克拉霉素a型结晶
CA2533358C (en) *	2003-07-21	2014-03-11	Advancis Pharmaceutical Corporation	Antibiotic product, use and formulation thereof
AU2004258953B2 (en) *	2003-07-21	2011-02-10	Shionogi, Inc.	Antibiotic product, use and formulation thereof
WO2005009365A2 (en) *	2003-07-21	2005-02-03	Advancis Pharmaceutical Corporation	Antibiotic product, use and formulation thereof
US8758820B2 (en) *	2003-08-11	2014-06-24	Shionogi Inc.	Robust pellet
JP2007502294A (ja) *	2003-08-12	2007-02-08	アドバンシスファーマスーティカルコーポレイション	抗生物質製剤、その使用法及び作成方法
US8246996B2 (en) *	2003-08-29	2012-08-21	Shionogi Inc.	Antibiotic product, use and formulation thereof
JP2007513869A (ja) *	2003-09-15	2007-05-31	アドバンシスファーマスーティカルコーポレイション	抗生物質製剤、その使用法及び作成方法
WO2005061524A2 (en) *	2003-12-22	2005-07-07	Ranbaxy Laboratories Limited	Process for the preparation of form ii clarithromycin
JP2007517039A (ja) *	2003-12-24	2007-06-28	アドバンシスファーマスーティカルコーポレイション	変性放出製剤の吸収増強
US8715727B2 (en) *	2004-07-02	2014-05-06	Shionogi Inc.	Tablet for pulsed delivery
US20060111560A1 (en) *	2004-11-01	2006-05-25	Glenmark Pharmaceuticals Limited	Process for the preparation of crystalline form II of clarithromycin
CA2614412A1 (en) *	2005-07-07	2007-01-18	Elan Pharma International, Limited	Nanoparticulate clarithromycin formulations
WO2007036951A2 (en) *	2005-08-31	2007-04-05	Alembic Limited	Process to obtain 6-o-methylerythromycin a (clarithromycin)_form ii
US8778924B2 (en) *	2006-12-04	2014-07-15	Shionogi Inc.	Modified release amoxicillin products
US8357394B2 (en)	2005-12-08	2013-01-22	Shionogi Inc.	Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en)	2006-05-05	2012-10-30	Shionogi Inc.	Pharmaceutical compositions and methods for improved bacterial eradication
DE102007016367A1 (de)	2007-04-03	2008-10-09	Grünenthal GmbH	Polymorph von Clarithromycin (Form V)
WO2009023191A2 (en) *	2007-08-09	2009-02-19	Teva Pharmaceutical Industries Ltd.	An improved process for the preparation of clarithromycin
EP2030613A1 (de)	2007-08-17	2009-03-04	Abbott GmbH & Co. KG	Herstellung von Zusammensetzungen mit hauptsächlich nichtkristallinen eingebetteten Makrolid-Antibiotika
CN101525360B (zh) *	2008-03-06	2012-10-10	刘力	大环内酯类有机酸盐的水合物及其制备和用途
CN101812102B (zh) *	2009-02-21	2015-09-02	王凌峰	6-o-甲基红霉素a晶型v
CN102532222B (zh) *	2010-12-21	2015-06-17	北大方正集团有限公司	一种麦迪霉素的结晶方法
US9119769B2 (en)	2011-12-30	2015-09-01	The Curators Of The University Of Missouri	Method for transforming pharmaceutical crystal forms
CN102942607A (zh) *	2012-11-28	2013-02-27	宁夏启元药业有限公司	一种复合溶剂结晶红霉素的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4331803A (en)	1980-06-04	1982-05-25	Taisho Pharmaceutical Co., Ltd.	Novel erythromycin compounds
JPS5782400A (en) *	1980-11-12	1982-05-22	Taisho Pharmaceut Co Ltd	Erythromycin derivative
JPS60214796A (ja) *	1984-04-06	1985-10-28	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja)	1984-10-26	1986-05-22	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) *	1985-03-18	1987-06-02	Taisho Pharmaceutical Co., Ltd.	Method for selective methylation of erythromycin a derivatives
DE3782994T2 (de)	1986-09-18	1993-04-08	Taisho Pharma Co Ltd	Erythromycin-a-derivate und verfahren zu ihrer herstellung.
JPH0755958B2 (ja) *	1986-10-03	1995-06-14	大正製薬株式会社	エリスロマイシンａ誘導体の製造方法
KR960000434B1 (ko) *	1986-12-17	1996-01-06	다이쇼 세이야꾸 가부시끼가이샤	에리스로마이신 a유도체 및 그의 제조 방법
JP2526951B2 (ja) *	1986-12-17	1996-08-21	大正製薬株式会社	エリスロマイシンａ誘導体およびその製造方法
JP2782793B2 (ja) *	1988-06-15	1998-08-06	大正製薬株式会社	エリスロマイシンａ誘導体およびその製造方法
US5872229A (en) *	1995-11-21	1999-02-16	Abbott Laboratories	Process for 6-O-alkylation of erythromycin derivatives
US5719272A (en)	1996-04-02	1998-02-17	Abbott Laboratories	2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5837829A (en)	1996-04-02	1998-11-17	Abbott Laboratories	9-oximesilyl erythromycin a derivatives

1996
- 1996-07-29 US US08/681,723 patent/US5858986A/en not_active Expired - Lifetime
1997
- 1997-07-25 JP JP10509015A patent/JP2000515894A/ja active Pending
- 1997-07-25 DE DE69726577T patent/DE69726577T2/de not_active Revoked
- 1997-07-25 ES ES97934307T patent/ES2173056T3/es not_active Expired - Lifetime
- 1997-07-25 AT AT97934307T patent/ATE255589T1/de not_active IP Right Cessation
- 1997-07-25 IL IL12758197A patent/IL127581A/en not_active IP Right Cessation
- 1997-07-25 CA CA002258606A patent/CA2258606C/en not_active Expired - Lifetime
- 1997-07-25 NZ NZ333380A patent/NZ333380A/xx not_active IP Right Cessation
- 1997-07-25 CN CN971968195A patent/CN1216892C/zh not_active Expired - Lifetime
- 1997-07-25 AU AU37397/97A patent/AU3739797A/en not_active Abandoned
- 1997-07-25 CA CA002627035A patent/CA2627035A1/en not_active Abandoned
- 1997-07-25 BR BR9710768A patent/BR9710768A/pt not_active Application Discontinuation
- 1997-07-25 WO PCT/US1997/013128 patent/WO1998004573A1/en not_active Ceased
- 1997-07-25 EP EP97934307A patent/EP0915898B1/de not_active Revoked
- 1997-07-25 PT PT97934307T patent/PT915898E/pt unknown
- 1997-07-25 DK DK97934307T patent/DK0915898T3/da active
- 1997-07-25 TR TR1999/00083T patent/TR199900083T2/xx unknown
- 1997-07-25 KR KR10-1999-7000715A patent/KR100498800B1/ko not_active Expired - Fee Related
- 1997-07-25 CZ CZ199999A patent/CZ294446B6/cs not_active IP Right Cessation
- 1997-07-25 CN CNA2005100859158A patent/CN1754884A/zh active Pending
2009
- 2009-12-10 JP JP2009280116A patent/JP5290136B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR20000029644A (ko)	2000-05-25
DE69726577D1 (en)	2004-01-15
US5858986A (en)	1999-01-12
CN1754884A (zh)	2006-04-05
DE69726577T2 (de)	2004-11-04
TR199900083T2 (xx)	1999-04-21
BR9710768A (pt)	1999-08-17
PT915898E (pt)	2004-02-27
CN1216892C (zh)	2005-08-31
ES2173056T3 (es)	2004-06-16
DK0915898T3 (da)	2004-02-16
JP2010090156A (ja)	2010-04-22
WO1998004573A1 (en)	1998-02-05
CA2627035A1 (en)	1998-02-05
AU3739797A (en)	1998-02-20
IL127581A (en)	2004-06-20
CA2258606A1 (en)	1998-02-05
CA2258606C (en)	2003-05-27
EP0915898A1 (de)	1999-05-19
KR100498800B1 (ko)	2005-07-01
CZ9999A3 (cs)	1999-05-12
CZ294446B6 (cs)	2005-01-12
EP0915898B1 (de)	2003-12-03
NZ333380A (en)	2000-01-28
JP5290136B2 (ja)	2013-09-18
ES2173056T1 (es)	2002-10-16
CN1229411A (zh)	1999-09-22
JP2000515894A (ja)	2000-11-28
IL127581A0 (en)	1999-10-28

Legal Events

Date

Code

Title

Description

2004-09-15

UEP

Publication of translation of european patent specification

Ref document number: 0915898

Country of ref document: EP

2006-03-15

RZN

Patent revoked

Publication	Publication Date	Title
ATE255589T1 (de)	2003-12-15	Kristallin form i von clarithromycin
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