ATE256462T1 - Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung - Google Patents

Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung

Info

Publication number
ATE256462T1
ATE256462T1 AT96935410T AT96935410T ATE256462T1 AT E256462 T1 ATE256462 T1 AT E256462T1 AT 96935410 T AT96935410 T AT 96935410T AT 96935410 T AT96935410 T AT 96935410T AT E256462 T1 ATE256462 T1 AT E256462T1
Authority
AT
Austria
Prior art keywords
production
water
pct
soluble vitamin
date mar
Prior art date
Application number
AT96935410T
Other languages
English (en)
Inventor
Hiroshi Ashida
Daisuke Izutsu
Akio Yamashita
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of ATE256462T1 publication Critical patent/ATE256462T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96935410T 1996-09-05 1996-10-23 Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung ATE256462T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23494096A JP4098376B2 (ja) 1996-09-05 1996-09-05 錠剤特性の優れた水溶性ビタミン組成物およびその製造法
PCT/JP1996/003079 WO1998009624A1 (fr) 1996-09-05 1996-10-23 Composition vitaminique hydrosoluble fournissant de remarquables comprimes et technique de production

Publications (1)

Publication Number Publication Date
ATE256462T1 true ATE256462T1 (de) 2004-01-15

Family

ID=16978662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96935410T ATE256462T1 (de) 1996-09-05 1996-10-23 Wasserlösliche vitaminzubereitung, zur herstellung ausgezeichneter tabletten undverfahren zu deren herstellung

Country Status (12)

Country Link
US (1) US5994324A (de)
EP (1) EP0974355B1 (de)
JP (1) JP4098376B2 (de)
KR (1) KR100441114B1 (de)
CN (1) CN1229356A (de)
AT (1) ATE256462T1 (de)
AU (1) AU7335696A (de)
DE (1) DE69631174T2 (de)
DK (1) DK0974355T3 (de)
ES (1) ES2213182T3 (de)
PT (1) PT974355E (de)
WO (1) WO1998009624A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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JP3419729B2 (ja) * 2000-03-16 2003-06-23 株式会社ファンケル 錠剤およびその製造方法
US6767899B1 (en) 2000-08-29 2004-07-27 Leiner Health Services Corp. Composition and method for treatment of conditions having an inflammatory component
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
CN1325049C (zh) * 2001-07-30 2007-07-11 Dsmip资产有限公司 含有表没食子儿茶素没食子酸酯的组合物
JP3980851B2 (ja) * 2001-08-30 2007-09-26 有限会社ゴトーコーポレーション 固型製剤、その製造方法、及び食品
KR100439979B1 (ko) * 2001-11-06 2004-07-12 샘즈바이오 주식회사 이중 코팅된 순수 비타민-씨 및 그를 함유하는 화장료 조성물과 화장료 조성물 제조방법
CA2470495A1 (en) * 2001-12-24 2003-07-17 Teva Pharmaceutical Industries Ltd. Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material, and process and tooling for producing it
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
KR20060135022A (ko) * 2004-04-14 2006-12-28 교와 핫꼬 고교 가부시끼가이샤 분기 사슬 아미노산을 함유하는 정제 및 그 제조 방법
CN100431515C (zh) * 2005-05-24 2008-11-12 浙江大学 稳定微粒化药物添加剂的制备方法
ZA200807571B (en) 2006-03-01 2009-08-26 Ethypharm Sa Crush-resistant tablets intended to prevent accidental misuse and unlawful diversion
WO2008046799A2 (de) * 2006-10-20 2008-04-24 Basf Aktiengesellschaft Preparation of granules of hydrophilic vitamins
JP2010024181A (ja) * 2008-07-18 2010-02-04 Takeda Chem Ind Ltd 固形製剤及びその製造方法
JP5733930B2 (ja) * 2009-09-09 2015-06-10 武田薬品工業株式会社 固形製剤
BR112012012999A2 (pt) * 2009-11-30 2019-04-02 Aptalis Pharmatech, Inc. Composição farmacêutica, e composição de tablete de desintegração oral (odt) outablete de dispersão rápida (rdt)
US10653632B2 (en) 2011-02-28 2020-05-19 Monash University Binder powders
CN107772478A (zh) * 2016-08-24 2018-03-09 南京逐陆医药科技有限公司 一种复合维生素片及其制备方法
JPWO2019013234A1 (ja) * 2017-07-11 2020-07-02 武田コンシューマーヘルスケア株式会社 ビタミンｂ１類を配合する固形製剤
CN113974171A (zh) * 2021-11-08 2022-01-28 北京素维生物科技有限公司 一种微水快溶组合物、微水快溶食品或药品以及其制备方法

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US3293132A (en) * 1963-03-25 1966-12-20 Merck & Co Inc Spray dried vitamin compositions and method of preparation
ZA739588B (en) * 1973-01-18 1974-11-27 Hoffmann La Roche Stabilized powder
JPS5114522A (en) * 1974-07-26 1976-02-05 Komatsu Mfg Co Ltd Kakyuenjinno kyufukajihaikishokukaizensochi
NL184308C (nl) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd Werkwijze voor het bereiden van l-ascorbienzuurgranules.
JPS58403B2 (ja) * 1975-07-24 1983-01-06 武田薬品工業株式会社 Ｌ− アスコルビンサンセイザイノ セイゾウホウ
DE2706660A1 (de) * 1977-02-17 1978-08-24 Merck Patent Gmbh Ascorbinsaeure enthaltende granulate und verfahren zu ihrer herstellung
JPS5555112A (en) * 1978-10-19 1980-04-22 Sumitomo Chem Co Ltd Preparation of biotin preparation rapidly soluble in water
JPS5749143A (en) * 1980-09-09 1982-03-20 Matsushita Electric Works Ltd Circuit breaker
JPS5759803A (en) * 1980-09-30 1982-04-10 Takeda Chem Ind Ltd Granule of l-sodium ascorbate, its preparation, and tablet comprising it
JPS5879917A (ja) * 1981-11-09 1983-05-13 Showa Denko Kk グリシン錠剤の成形方法
WO1985001877A1 (en) * 1983-10-24 1985-05-09 Basf Wyandotte Corporation A process for preparation spray-dried powders containing a water-soluble vitamin and powders prepared thereby
JPH0753663B2 (ja) * 1984-10-09 1995-06-07 武田薬品工業株式会社 チアミン塩の顆粒，その製造法および錠剤
DE3447422A1 (de) * 1984-12-24 1986-06-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von ascorbinsaeure-granulat
AU587863B2 (en) * 1985-10-07 1989-08-31 Basf Aktiengesellschaft Vitamin-containing granules and production thereof
JPH0761961B2 (ja) * 1986-06-24 1995-07-05 信越化学工業株式会社 被覆薬剤の製造方法
JPH01165519A (ja) * 1987-12-22 1989-06-29 Ohara Kako Kk 水溶性及び／又は脂溶性ビタミン粒状製剤及びその製造方法
JPH01296953A (ja) * 1988-05-24 1989-11-30 Freunt Ind Co Ltd ビタミンｃ組成物、それを添加した飼料およびその製造方法
JP2880243B2 (ja) * 1989-04-18 1999-04-05 武田薬品工業株式会社 アスコルビン酸カルシウム造粒物
JPH02282323A (ja) * 1989-04-21 1990-11-19 Shin Etsu Chem Co Ltd 徐放性錠剤の製造方法
EP0416773B1 (de) * 1989-08-31 1993-03-03 Takeda Chemical Industries, Ltd. Vitamin-B12-Zusammensetzung
US5236920A (en) * 1990-04-30 1993-08-17 Basf Corporation Granulated riboflavin product having high flowability, high riboflavin content
US5254551A (en) * 1990-04-30 1993-10-19 Kirk Paula S Flour fortification formulation comprising granulated riboflavin
US5000888A (en) * 1990-05-23 1991-03-19 Basf Corporation Process for spray drying riboflavin to produce a granulate product having low binder content
JP3119801B2 (ja) * 1995-09-28 2000-12-25 武田薬品工業株式会社 ビタミン含有組成物の安定化方法

Also Published As

Publication number Publication date
CN1229356A (zh) 1999-09-22
KR20000029837A (ko) 2000-05-25
DE69631174T2 (de) 2004-09-02
JPH1077224A (ja) 1998-03-24
US5994324A (en) 1999-11-30
WO1998009624A1 (fr) 1998-03-12
EP0974355B1 (de) 2003-12-17
PT974355E (pt) 2004-04-30
KR100441114B1 (ko) 2004-07-19
JP4098376B2 (ja) 2008-06-11
EP0974355A4 (de) 2000-12-20
DE69631174D1 (de) 2004-01-29
DK0974355T3 (da) 2004-04-19
ES2213182T3 (es) 2004-08-16
AU7335696A (en) 1998-03-26
EP0974355A1 (de) 2000-01-26

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