ATE260279T1 - Naphthyridin-derivate mit cytomegalovirus inhibierender wirkung - Google Patents

Naphthyridin-derivate mit cytomegalovirus inhibierender wirkung

Info

Publication number: ATE260279T1
Authority: AT; Austria
Prior art keywords: cytomegalovirus; inhibiting effect; naphthyridine derivatives; compounds; naphthyridine
Prior art date: 1996-03-15

Application number

AT97906955T

Other languages

English (en)

Inventor

Haolun Jin

Laval Chun Chan

Wei Wang

Tomislav Stefanac

Tarek S Mansour

Paul Nguyen-Ba

Jean-Francois Lavallee

Guy Falardeau

Original Assignee

Iaf Biochem Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-15

Filing date

1997-03-14

Publication date

2004-03-15

1997-03-14 Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int

2004-03-15 Application granted granted Critical

2004-03-15 Publication of ATE260279T1 publication Critical patent/ATE260279T1/de

Links

241000701022 Cytomegalovirus Species 0.000 title abstract 3
150000005054 naphthyridines Chemical class 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title 1
241000124008 Mammalia Species 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT97906955T 1996-03-15 1997-03-14 Naphthyridin-derivate mit cytomegalovirus inhibierender wirkung ATE260279T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9605437.4A GB9605437D0 (en)	1996-03-15	1996-03-15	Cytomegalovirus inhibiting compounds
PCT/CA1997/000182 WO1997034894A1 (en)	1996-03-15	1997-03-14	Naphthyridine derivatives and their analogues inhibiting cytomegalovirus

Publications (1)

Publication Number	Publication Date
ATE260279T1 true ATE260279T1 (de)	2004-03-15

Family

ID=10790420

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97906955T ATE260279T1 (de)	1996-03-15	1997-03-14	Naphthyridin-derivate mit cytomegalovirus inhibierender wirkung

Country Status (12)

Country	Link
EP (1)	EP0984967B1 (de)
JP (1)	JP2001515464A (de)
CN (1)	CN1069643C (de)
AT (1)	ATE260279T1 (de)
AU (1)	AU722650B2 (de)
BR (1)	BR9708068A (de)
CA (1)	CA2250320A1 (de)
DE (1)	DE69727838D1 (de)
GB (2)	GB9605437D0 (de)
TW (1)	TW480258B (de)
WO (1)	WO1997034894A1 (de)
ZA (1)	ZA972292B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9711257D0 (en) *	1997-05-30	1997-07-30	Smithkline Beecham Plc	Novel compounds
CN1283995A (zh)	1997-12-11	2001-02-14	生化制药有限公司	抗病毒化合物
US6340690B1 (en)	1999-02-22	2002-01-22	Bio-Chem Pharma Inc.	Antiviral methods using [1,8]naphthyridine derivatives
DE19912638A1 (de) *	1999-03-20	2000-09-21	Bayer Ag	Naphthylcarbonsäureamid-substituierte Sulfonamide
US6562822B2 (en)	2000-07-12	2003-05-13	Pharmacia & Upjohn Company	Heterocyle carboxamides as antiviral agents
US6559145B2 (en)	2000-07-12	2003-05-06	Pharmacia & Upjohn Company	Heterocycle carboxamides as antiviral agents
US6730682B2 (en)	2000-07-12	2004-05-04	Pharmacia & Upjohn Company	Heterocycle carboxamides as antiviral agents
AU2002218902A1 (en) *	2000-12-27	2002-07-08	Shire Biochem Inc.	Macrocyclic anti-viral compounds
EP1372648B1 (de)	2001-01-19	2006-03-15	Smithkline Beecham Corporation	Tie2 rezeptor-kinase-inhibitoren zur behandlung von angiogenen erkrankungen
WO2005033079A1 (ja) *	2003-09-30	2005-04-14	Eisai Co., Ltd.	ヘテロ環化合物を含有する新規な抗真菌剤
EP1833832A1 (de) *	2004-12-31	2007-09-19	GPC Biotech AG	Naphthyridinverbindungen als rock-inhibitoren
TWI385169B (zh)	2005-10-31	2013-02-11	Eisai R&D Man Co Ltd	經雜環取代之吡啶衍生物及含有彼之抗真菌劑
EP2065377B1 (de)	2006-09-21	2011-11-23	Eisai R&D Management Co., Ltd.	Durch einen heteroarylring substituiertes pyridinderivat und antipilzmittel, das dieses enthält
WO2008136279A1 (ja)	2007-04-27	2008-11-13	Eisai R & D Management Co., Ltd.	ヘテロ環置換ピリジン誘導体の塩またはその結晶
TW200841879A (en)	2007-04-27	2008-11-01	Eisai R&D Man Co Ltd	Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
US8258301B2 (en) *	2007-05-15	2012-09-04	Boehringer Ingelheim International Gmbh	Urotensin II receptor antagonists
US8513287B2 (en)	2007-12-27	2013-08-20	Eisai R&D Management Co., Ltd.	Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en)	2008-10-24	2012-05-29	Eisai R&D Management Co., Ltd	Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
CN104812387A (zh)	2012-11-20	2015-07-29	霍夫曼-拉罗奇有限公司	取代的1,6-萘啶

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4786644A (en) *	1987-11-27	1988-11-22	Hoechst-Roussel Pharmaceuticals Inc.	1-aryl-3-quinolinecarboxamide
JPH02237922A (ja) *	1989-01-24	1990-09-20	Green Cross Corp:The	抗ウィルス剤
AU5449590A (en) *	1989-04-28	1990-11-29	Daiichi Pharmaceutical Co., Ltd.	Anti-hiv drug
US4959363A (en) *	1989-06-23	1990-09-25	Sterling Drug Inc.	Quinolonecarboxamide compounds, their preparation and use as antivirals.
US5516784A (en) *	1991-08-13	1996-05-14	Schering Corporation	Anti-HIV (AIDS) agents
WO1994008456A1 (en) *	1992-10-21	1994-04-28	The Regents Of The University Of Michigan	Polysubstituted benzimidazoles as antiviral agents
DE4303657A1 (de) *	1993-02-09	1994-08-11	Bayer Ag	Neue Chinolon- und Naphthyridoncarbonsäurederivate
DE4331135A1 (de) *	1993-09-14	1995-03-16	Bayer Ag	Neue antiviral wirksame valinhaltige Pseudopeptide
US5543413A (en) *	1994-02-25	1996-08-06	Regents Of The University Of Michigan	Heterocyclic thioamides and related analogs as antiviral agents with a unique mode of action
EP0784470B1 (de) *	1994-10-03	2003-08-13	INFECTIO RECHERCHE Inc.	Liposomenzubereitungen zur behandlung von viruserkrankungen
WO1997004775A1 (en) *	1995-08-02	1997-02-13	Chiroscience Limited	Quinolones and their therapeutic use

1996
- 1996-03-15 GB GBGB9605437.4A patent/GB9605437D0/en active Pending
1997
- 1997-03-14 AU AU19187/97A patent/AU722650B2/en not_active Ceased
- 1997-03-14 WO PCT/CA1997/000182 patent/WO1997034894A1/en not_active Ceased
- 1997-03-14 GB GB9819782A patent/GB2326412A/en not_active Withdrawn
- 1997-03-14 EP EP97906955A patent/EP0984967B1/de not_active Expired - Lifetime
- 1997-03-14 AT AT97906955T patent/ATE260279T1/de not_active IP Right Cessation
- 1997-03-14 DE DE69727838T patent/DE69727838D1/de not_active Expired - Lifetime
- 1997-03-14 CN CN97194535A patent/CN1069643C/zh not_active Expired - Fee Related
- 1997-03-14 BR BR9708068-3A patent/BR9708068A/pt unknown
- 1997-03-14 CA CA002250320A patent/CA2250320A1/en not_active Abandoned
- 1997-03-14 JP JP53299797A patent/JP2001515464A/ja active Pending
- 1997-03-17 ZA ZA9702292A patent/ZA972292B/xx unknown
- 1997-03-19 TW TW086103467A patent/TW480258B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU1918797A (en)	1997-10-10
GB9605437D0 (en)	1996-05-15
BR9708068A (pt)	2000-01-04
ZA972292B (en)	1997-10-16
DE69727838D1 (de)	2004-04-01
EP0984967B1 (de)	2004-02-25
GB9819782D0 (en)	1998-11-04
JP2001515464A (ja)	2001-09-18
GB2326412A (en)	1998-12-23
EP0984967A1 (de)	2000-03-15
CN1218473A (zh)	1999-06-02
CA2250320A1 (en)	1997-09-25
CN1069643C (zh)	2001-08-15
AU722650B2 (en)	2000-08-10
TW480258B (en)	2002-03-21
WO1997034894A1 (en)	1997-09-25

Legal Events

Date	Code	Title	Description
2004-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69727838D1 (de)	2004-04-01	Naphthyridin-derivate mit cytomegalovirus inhibierender wirkung
ATE249219T1 (de)	2003-09-15	Antivirale verbindungen
NO20003233D0 (no)	2000-06-21	4-hydrokykinolin-3-karboksamider og hydraziner som antivirale midler
ATE231149T1 (de)	2003-02-15	(1,8)-naphthyridinderivate derivate mit antiviraler wirkung
DE69811062D1 (de)	2003-03-06	Polyaromatische antivirale zusammensetzungen
MX9102407A (es)	1994-05-31	4 arilpiperazinas y 4-arilpiperidinas novedosas.
DE69426904D1 (de)	2001-04-26	Phosphonat-Nukleotid Ester-Derivate
DK0425650T3 (da)	1995-12-27	Antiinflammatoriske 4-aminophenolderivater
ATE258930T1 (de)	2004-02-15	Dihydrobenzifurane
NO933611L (no)	1993-10-08	Anti-tumor- og anti-psoriatiske midler
ATE224372T1 (de)	2002-10-15	Substituierte 6-alkylphenanthridine
ATE242220T1 (de)	2003-06-15	Benzimidazolderivate mit dopaminerger wirkung
CA2144344A1 (en)	1994-03-31	Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents
WO2002051413A3 (en)	2002-10-10	Macrocyclic anti-viral compounds
NO972905L (no)	1997-08-18	Tienoksasinon-derivater anvendelige som antivirusmidler
ATE215935T1 (de)	2002-04-15	Heterozyklische verbidungen mit mmp und tnf inhibitorisher wirkung
ATE247655T1 (de)	2003-09-15	Dreifachsubstituierte thioxanthine
DE69213049D1 (de)	1996-10-02	Isoquinolinderivate
YU106191A (sh)	1994-01-20	Aminobenzodiazepini