ATE262317T1 - Multilamellare anzneistoffabgabesysteme - Google Patents

Multilamellare anzneistoffabgabesysteme

Info

Publication number
ATE262317T1
ATE262317T1 AT95916160T AT95916160T ATE262317T1 AT E262317 T1 ATE262317 T1 AT E262317T1 AT 95916160 T AT95916160 T AT 95916160T AT 95916160 T AT95916160 T AT 95916160T AT E262317 T1 ATE262317 T1 AT E262317T1
Authority
AT
Austria
Prior art keywords
argent
multilamellar
delivery systems
hydrophobic
hydrophilic
Prior art date
Application number
AT95916160T
Other languages
English (en)
Inventor
George W Belenduik
Edward M Rudnic
John A Mccarty
Original Assignee
Shire Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Lab Inc filed Critical Shire Lab Inc
Application granted granted Critical
Publication of ATE262317T1 publication Critical patent/ATE262317T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95916160T 1994-04-07 1995-04-07 Multilamellare anzneistoffabgabesysteme ATE262317T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/224,340 US5447729A (en) 1994-04-07 1994-04-07 Multilamellar drug delivery systems
PCT/US1995/004036 WO1995027479A1 (en) 1994-04-07 1995-04-07 Multilamellar drug delivery systems

Publications (1)

Publication Number Publication Date
ATE262317T1 true ATE262317T1 (de) 2004-04-15

Family

ID=22840237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916160T ATE262317T1 (de) 1994-04-07 1995-04-07 Multilamellare anzneistoffabgabesysteme

Country Status (10)

Country Link
US (1) US5447729A (de)
EP (1) EP0754031B1 (de)
JP (1) JPH09511744A (de)
AT (1) ATE262317T1 (de)
AU (1) AU695053B2 (de)
CA (1) CA2187202C (de)
DE (1) DE69532753T2 (de)
ES (1) ES2217278T3 (de)
MX (1) MX9604490A (de)
WO (1) WO1995027479A1 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
DE69535127T2 (de) * 1994-03-18 2007-02-15 Supernus Pharmaceuticals, Inc. Emulgierte arzneistoffabgabesysteme
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6395303B1 (en) * 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5653987A (en) * 1995-05-16 1997-08-05 Modi; Pankaj Liquid formulations for proteinic pharmaceuticals
US5883103A (en) * 1995-06-07 1999-03-16 Shire Laboratories Inc. Oral acyclovir delivery
WO1997002815A1 (fr) * 1995-07-07 1997-01-30 Nippon Kayaku Kabushiki Kaisha Composition de flutamide
US5593682A (en) * 1995-12-29 1997-01-14 Eastman Chemical Company Skin treating composition
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
US6440980B1 (en) * 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
CA2275604A1 (en) * 1997-01-03 1998-07-09 Kenneth Iain Cumming Sustained release cisapride mini-tablet formulation
GB2321455A (en) 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US5922352A (en) * 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
AU1508899A (en) * 1997-12-02 1999-06-16 Chong Kun Dang Corporation Pharmaceutical composition comprising cyclosporin solid-state microemulsion
US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
GB9726916D0 (en) 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
DE19814014A1 (de) * 1997-12-19 1999-09-30 Krewel Meuselbach Gmbh Arzneipflanzentrockenextrakte
US6017545A (en) * 1998-02-10 2000-01-25 Modi; Pankaj Mixed micellar delivery system and method of preparation
US7070799B1 (en) * 1998-02-10 2006-07-04 Generex Pharmaceuticals, Inc. Method for administering insulin to the buccal region
US6221378B1 (en) 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
US6184196B1 (en) 1998-05-27 2001-02-06 University Of Iowa Research Foundation Sucrose based surfactants and methods thereof
ITMI981528A1 (it) * 1998-07-03 2000-01-03 Recordati Ind Chimica E Farma Formulazioni topiche di aciclovir
TR200200562T2 (tr) 1999-06-14 2002-05-21 Cosmo S.P.A Vücutta kontrollü şekilde salgılanabilen ve nahoş tadı önleyebilen ağızdan alınmaya mahsus farmasötik bileşimler
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
US6747058B1 (en) 1999-08-20 2004-06-08 Unimed Pharmaceuticals, Inc. Stable composition for inhalation therapy comprising delta-9-tetrahydrocannabinol and semiaqueous solvent therefor
US7648696B2 (en) * 1999-08-20 2010-01-19 Unimed Pharmaceuticals, Llc Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US7220430B2 (en) * 2000-01-27 2007-05-22 Tanabe Seiyaku Co., Ltd. Sustained-release preparation and process for producing the same
US6596306B1 (en) * 2000-07-07 2003-07-22 David Ho Sue San Ho Drug delivery system:formulation for fat-soluble drugs
AU1167702A (en) * 2000-10-11 2002-04-22 Cephalon Inc Compositions comprising modafinil compounds
US6524615B2 (en) * 2001-02-21 2003-02-25 Kos Pharmaceuticals, Incorporated Controlled release pharmaceutical composition
US20030143272A1 (en) * 2001-03-14 2003-07-31 Waterman Kenneth C. Pharmaceutical tablet and process for making thereof
EP1436006A4 (de) * 2001-10-16 2006-06-07 Avanir Pharmaceuticals Virushemmung mit n-docosanol
FR2839645B1 (fr) * 2002-05-15 2005-08-05 Backert Marie Elisabeth Cuine Systeme multilamellaire pour l'administration de substances actives (en particulier des medicaments) par ingestion par la voie orale
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
HUE031092T2 (en) * 2003-07-17 2017-07-28 Banner Life Sciences Llc Controlled release preparations
US7456306B2 (en) 2003-07-28 2008-11-25 Mallinckrodt Inc Stearate composition and method of production thereof
CA2569964A1 (en) * 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
US20060088591A1 (en) * 2004-10-22 2006-04-27 Jinghua Yuan Tablets from a poorly compressible substance
MX2007007038A (es) * 2004-12-09 2008-03-07 Insys Therapeutics Inc Formulacion de dronabinol en temperatura ambiente.
US20060240108A1 (en) * 2005-04-26 2006-10-26 Bernard Bobby L Cellulosic films incorporating a pharmaceutically acceptable plasticizer with enhanced wettability
US9743680B2 (en) 2005-10-14 2017-08-29 Wild Flavors, Inc. Microemulsions for use in food and beverage products
WO2007050724A2 (en) * 2005-10-26 2007-05-03 Banner Pharmacaps, Inc. Lipophilic vehicle-based dual controlled release matrix system as capsule fill
CN101360485B (zh) * 2005-10-26 2013-04-17 班纳制药公司 作为胶囊填充物的基于亲水性载体的双重控释基质系统
US9265724B2 (en) 2005-11-07 2016-02-23 Ram B. Murty Oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
WO2008019146A2 (en) * 2006-08-04 2008-02-14 Insys Therapeutics Inc. Aqueous dronabinol formulations
US20090181080A1 (en) * 2007-08-06 2009-07-16 Insys Therapeutics Inc. Oral cannabinnoid liquid formulations and methods of treatment
US8394391B2 (en) * 2007-08-31 2013-03-12 University Of Utah Research Foundation Drug delivery vehicle that mimics viral properties
WO2009042114A2 (en) 2007-09-21 2009-04-02 The Johns Hopkins University Phenazine derivatives and uses thereof
EP2044932A1 (de) * 2007-10-04 2009-04-08 Laboratorios del Dr. Esteve S.A. Mechanische Schutzschicht für feste Darreichungsformen
JP5568093B2 (ja) * 2008-12-18 2014-08-06 ビーエーエスエフ ソシエタス・ヨーロピア 農薬粒子と両親媒性物質とを含む水性分散液
NZ599344A (en) 2009-09-25 2015-02-27 Reddy’S Lab Ltd Dr Formulations comprising triptan compounds
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
WO2012033478A1 (en) * 2010-09-07 2012-03-15 Murty Pharmaceuticals, Inc. An improved oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
JP6339940B2 (ja) 2011-12-20 2018-06-06 ビョーメ バイオサイエンシズ ピーブイティー．リミテッド 真菌感染症の治療用の局所用オイル組成物
KR101814895B1 (ko) * 2013-06-04 2018-01-04 바이옴 바이오사이언스 피브이티. 엘티디. 코팅된 입자 및 이를 포함하는 조성물

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202888A (en) * 1976-07-12 1980-05-13 Kali-Chemie Pharma Gmbh. Readily enterally absorbable pharmaceutical compositions of cardiac glycosides and preparation thereof
JPS5940137B2 (ja) * 1976-10-14 1984-09-28 武田薬品工業株式会社 経口投与用医薬組成物
GB2009698B (en) * 1977-12-13 1982-05-26 British Petroleum Co Preparation of emulsions
JPS5498318A (en) * 1978-01-10 1979-08-03 Kali Chemie Pharma Gmbh Intestinally dosing and highly absorbable preparation of respiration difficult medicene and production thereof
JPS54122719A (en) * 1978-03-16 1979-09-22 Sankyo Co Ltd Carcinostatic agent for oral administration
JPS557228A (en) * 1978-06-29 1980-01-19 Lion Corp Enzyme preparation
JPS5612309A (en) * 1979-07-11 1981-02-06 Kyowa Hakko Kogyo Co Ltd Oral drug containing ubidecarenone
JPS5618914A (en) * 1979-07-25 1981-02-23 Eisai Co Ltd Ubidecarenone composition having good absorbability
JPS5913717A (ja) * 1982-07-16 1984-01-24 Asahi Chem Ind Co Ltd エマルジヨン製剤
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
JPS60215633A (ja) * 1984-04-11 1985-10-29 Terumo Corp 腸管吸収性ウロキナ−ゼリポソ−ム組成物
JPS61221131A (ja) * 1985-03-28 1986-10-01 Eisai Co Ltd 吸収促進したユビデカレノン含有組成物
JPH0629180B2 (ja) * 1986-06-16 1994-04-20 エーザイ株式会社 吸収性の改良されたメナテトレノン含有組成物
IL88083A (en) * 1987-11-06 1992-11-15 Tanabe Seiyaku Co Controlled release pharmaceutical dosage form and its preparation
JPH07552B2 (ja) * 1987-11-06 1995-01-11 田辺製薬株式会社 持効性製剤
US5350741A (en) * 1988-07-30 1994-09-27 Kanji Takada Enteric formulations of physiologically active peptides and proteins
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
DE69011618T2 (de) * 1989-05-11 1994-12-15 Chugai Pharmaceutical Co Ltd Mundzubereitung zur verabreichung an bestimmter stelle des darmes.

Also Published As

Publication number Publication date
MX9604490A (es) 1997-11-29
ES2217278T3 (es) 2004-11-01
EP0754031A4 (de) 2000-01-19
CA2187202A1 (en) 1995-10-19
AU2276095A (en) 1995-10-30
DE69532753T2 (de) 2005-01-27
WO1995027479A1 (en) 1995-10-19
EP0754031B1 (de) 2004-03-24
EP0754031A1 (de) 1997-01-22
DE69532753D1 (de) 2004-04-29
JPH09511744A (ja) 1997-11-25
AU695053B2 (en) 1998-08-06
US5447729A (en) 1995-09-05
CA2187202C (en) 2000-11-21

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties