ATE263769T1 - Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen - Google Patents

Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen

Info

Publication number: ATE263769T1
Authority: AT; Austria
Prior art keywords: cerebral; preventing; present; diseases; various
Prior art date: 1997-01-16

Application number

AT98900228T

Other languages

English (en)

Inventor

Hiroshi Nagase

Yoshifumi Imamura

Junichi Hirokawa

Susumu Matsuda

Yasushi Miyauchi

Original Assignee

Toray Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-16

Filing date

1998-01-13

Publication date

2004-04-15

1998-01-13 Application filed by Toray Industries filed Critical Toray Industries

2004-04-15 Application granted granted Critical

2004-04-15 Publication of ATE263769T1 publication Critical patent/ATE263769T1/de

Links

230000002490 cerebral effect Effects 0.000 title abstract 4
229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
208000018152 Cerebral disease Diseases 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
-1 hydroxy, methoxy Chemical group 0.000 abstract 2
210000002569 neuron Anatomy 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
230000000472 traumatic effect Effects 0.000 abstract 2
206010048962 Brain oedema Diseases 0.000 abstract 1
206010056677 Nerve degeneration Diseases 0.000 abstract 1
208000006011 Stroke Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
208000006752 brain edema Diseases 0.000 abstract 1
208000029028 brain injury Diseases 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002008 hemorrhagic effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000000302 ischemic effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
230000004770 neurodegeneration Effects 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98900228T 1997-01-16 1998-01-13 Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen ATE263769T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP582997		1997-01-16
PCT/JP1998/000092 WO1998031684A1 (en)	1997-01-16	1998-01-13	Indolomorphinane derivatives and remedies/preventives for cerebral disorders

Publications (1)

Publication Number	Publication Date
ATE263769T1 true ATE263769T1 (de)	2004-04-15

Family

ID=11621945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98900228T ATE263769T1 (de)	1997-01-16	1998-01-13	Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen

Country Status (12)

Country	Link
US (1)	US6156762A (de)
EP (1)	EP0894799B1 (de)
JP (1)	JP4110579B2 (de)
KR (1)	KR100557804B1 (de)
CN (1)	CN1117754C (de)
AT (1)	ATE263769T1 (de)
AU (1)	AU739367B2 (de)
DE (1)	DE69822937T2 (de)
ES (1)	ES2217533T3 (de)
NO (1)	NO984263L (de)
NZ (1)	NZ331769A (de)
WO (1)	WO1998031684A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19939044A1 (de) *	1999-08-18	2001-03-15	Gruenenthal Gmbh	Verwendung von Morphinanderivaten als Arzneimittel
CN1204139C (zh) *	1999-08-24	2005-06-01	东丽株式会社	神经性疼痛治疗剂
US6809104B2 (en)	2001-05-04	2004-10-26	Tularik Inc.	Fused heterocyclic compounds
US6858619B2 (en)	2001-05-04	2005-02-22	Amgen Inc.	Fused heterocyclic compounds
CN101134757A (zh)	2002-11-06	2008-03-05	安姆根有限公司	稠合杂环化合物
US20100172909A1 (en) *	2005-10-24	2010-07-08	Masahiro Nishibori	Cerebral edema suppressant
US8829020B2 (en)	2009-07-16	2014-09-09	Mallinckrodt Llc	Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
JPWO2016167318A1 (ja) *	2015-04-16	2018-02-08	学校法人北里研究所	記憶改善剤及びその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4680172A (en) *	1985-03-05	1987-07-14	Ciba-Geigy Corporation	Devices and methods for treating memory impairment
US4816586A (en) *	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
JPH03218313A (ja) *	1989-11-22	1991-09-25	Toray Ind Inc	脳細胞保護剤
JP2906654B2 (ja) *	1989-11-28	1999-06-21	東レ株式会社	免疫抑制剤及びその製造方法
US5223507A (en) *	1992-01-21	1993-06-29	G. D. Searle & Co.	Method of using opioid compounds as delta opioid selective agonist analgesics
US5225417A (en) *	1992-01-21	1993-07-06	G. D. Searle & Co.	Opioid agonist compounds
US5852030A (en) *	1992-09-29	1998-12-22	Toray Industries, Inc.	Indole derivatives, process for producing the same and medicinal uses of the same
KR100301093B1 (ko) *	1992-09-29	2001-10-22	히라이 가쯔히꼬	인돌유도체,그제조방법및그의약용도
AU674379B2 (en) *	1992-12-22	1996-12-19	Toray Industries, Inc.	Antitussive
KR100341950B1 (ko) *	1993-07-19	2002-11-29	도레이 가부시끼가이샤	뇌세포보호제
NZ268969A (en) *	1993-07-23	1997-06-24	Toray Industries	Morphinan derivatives and pharmaceutical compositions
SE9401728D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds II
SE9401727D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds I

1998
- 1998-01-13 AU AU53437/98A patent/AU739367B2/en not_active Ceased
- 1998-01-13 KR KR1019980707314A patent/KR100557804B1/ko not_active Expired - Fee Related
- 1998-01-13 NZ NZ331769A patent/NZ331769A/xx unknown
- 1998-01-13 JP JP53410198A patent/JP4110579B2/ja not_active Expired - Fee Related
- 1998-01-13 WO PCT/JP1998/000092 patent/WO1998031684A1/ja not_active Ceased
- 1998-01-13 CN CN98800291A patent/CN1117754C/zh not_active Expired - Fee Related
- 1998-01-13 US US09/142,794 patent/US6156762A/en not_active Expired - Fee Related
- 1998-01-13 ES ES98900228T patent/ES2217533T3/es not_active Expired - Lifetime
- 1998-01-13 AT AT98900228T patent/ATE263769T1/de not_active IP Right Cessation
- 1998-01-13 DE DE69822937T patent/DE69822937T2/de not_active Expired - Fee Related
- 1998-01-13 EP EP98900228A patent/EP0894799B1/de not_active Expired - Lifetime
- 1998-09-15 NO NO984263A patent/NO984263L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE69822937D1 (de)	2004-05-13
WO1998031684A1 (en)	1998-07-23
EP0894799B1 (de)	2004-04-07
ES2217533T3 (es)	2004-11-01
KR20000064618A (ko)	2000-11-06
NZ331769A (en)	2000-05-26
EP0894799A1 (de)	1999-02-03
EP0894799A4 (de)	2001-08-16
AU5343798A (en)	1998-08-07
CN1117754C (zh)	2003-08-13
CN1220668A (zh)	1999-06-23
KR100557804B1 (ko)	2006-06-20
JP4110579B2 (ja)	2008-07-02
NO984263D0 (no)	1998-09-15
NO984263L (no)	1998-11-13
DE69822937T2 (de)	2004-08-12
AU739367B2 (en)	2001-10-11
US6156762A (en)	2000-12-05

Similar Documents

Publication	Publication Date	Title
DE69716810D1 (de)	2002-12-12	2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
IL162214A (en)	2011-08-31	Pyridine derivatives and pharmaceutical compositions containing the same
PT1259489E (pt)	2006-08-31	Compostos azapoliciclicos condensados con arilo.
EA200000592A1 (ru)	2000-12-25	Азаполициклические соединения, конденсированные с арилом
DE69736441D1 (de)	2006-09-14	Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
BR9917038A (pt)	2002-04-02	Composto, composição farmacêutica, método de modulação da atividade receptora de quimocinas, método de tratamento ou prevenção de doenças inflamatórias, método de tratamento ou prevenção de asma e método de tratamento ou prevenção de disfunções inflamatórias
ATE272398T1 (de)	2004-08-15	Verwendung von ep4 rezeptorliganden zur behandlung von neuropathischen schmerz
BR0316723A (pt)	2005-10-18	Derivados de anilinopirazol úteis para o tratamento de diabetes
DE69834500D1 (de)	2006-06-14	Xanthinderivative zur behandlung von hirnischämie
EA200000996A1 (ru)	2001-06-25	Конденсированные с арилом азаполициклические соединения
ATE263769T1 (de)	2004-04-15	Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen
BR9503572A (pt)	1996-04-30	Composto composiçao farmaceutica e método de tratamento ou prevençao de uma doença
CA2256336A1 (en)	1998-10-08	Quinolinomorphinan derivative and medical use thereof
DE602004014115D1 (de)	2008-07-10	Neue amidderivate von 2,2,3,3-tetramethylcyclopropancarbonsäure
PT889044E (pt)	2005-01-31	Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central
ATE252546T1 (de)	2003-11-15	3-(3-hydroxyphenyl)-3-amino-propionamidderivate
ATE314339T1 (de)	2006-01-15	Polyhydroxyphenolderivate und mittel zur vorbeugung und therapie von knochen- und knorpelkrankheiten die diese enthalten
CA2249240A1 (en)	1998-07-23	Indolomorphinan derivative and agent for curing and preventing cerebral disorder
ATE242766T1 (de)	2003-06-15	Neue derivate von benzoylalkyl-1,2,3,6- tetrahydropyridinen
ATE265459T1 (de)	2004-05-15	Triazolpurin-derivate, medikamentzusammensetzungen, die diese enthalten und mittel, die affinität zum adenosin a3 rezeptor zeigen
CA2270026A1 (en)	1999-10-29	Substituted bicyclic derivatives for treating central nervous system disorders
TH101398A3 (th)	2010-05-26	การใช้ประโยชน์จากอนุพันธ์ไอโซไธอะโซลเป็นสารต่อต้านมะเร็ง

Legal Events

Date	Code	Title	Description
2004-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties