NO984263L - Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse - Google Patents

Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse

Info

Publication number: NO984263L
Authority: NO; Norway
Prior art keywords: cerebral; preventing; present; derivative; diseases
Prior art date: 1997-01-16

Application number

NO984263A

Other languages

English (en)

Norwegian (no)

Other versions

NO984263D0 (no

Inventor

Hiroshi Nagase

Yoshifumi Imamura

Junichi Hirokawa

Susumu Matsuda

Yasushi Miyauchi

Original Assignee

Toray Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-16

Filing date

1998-09-15

Publication date

1998-11-13

1998-09-15 Application filed by Toray Industries filed Critical Toray Industries

1998-09-15 Publication of NO984263D0 publication Critical patent/NO984263D0/no

1998-11-13 Publication of NO984263L publication Critical patent/NO984263L/no

Links

206010008129 cerebral palsy Diseases 0.000 title 1
230000002265 prevention Effects 0.000 title 1
208000018152 Cerebral disease Diseases 0.000 abstract 4
230000002490 cerebral effect Effects 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
-1 hydroxy, methoxy Chemical group 0.000 abstract 2
210000002569 neuron Anatomy 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
230000000472 traumatic effect Effects 0.000 abstract 2
206010048962 Brain oedema Diseases 0.000 abstract 1
206010056677 Nerve degeneration Diseases 0.000 abstract 1
208000006011 Stroke Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
208000006752 brain edema Diseases 0.000 abstract 1
208000029028 brain injury Diseases 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002008 hemorrhagic effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000000302 ischemic effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
230000004770 neurodegeneration Effects 0.000 abstract 1
208000015122 neurodegenerative disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO984263A 1997-01-16 1998-09-15 Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse NO984263L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP582997		1997-01-16
PCT/JP1998/000092 WO1998031684A1 (en)	1997-01-16	1998-01-13	Indolomorphinane derivatives and remedies/preventives for cerebral disorders

Publications (2)

Publication Number	Publication Date
NO984263D0 NO984263D0 (no)	1998-09-15
NO984263L true NO984263L (no)	1998-11-13

Family

ID=11621945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO984263A NO984263L (no)	1997-01-16	1998-09-15	Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse

Country Status (12)

Country	Link
US (1)	US6156762A (de)
EP (1)	EP0894799B1 (de)
JP (1)	JP4110579B2 (de)
KR (1)	KR100557804B1 (de)
CN (1)	CN1117754C (de)
AT (1)	ATE263769T1 (de)
AU (1)	AU739367B2 (de)
DE (1)	DE69822937T2 (de)
ES (1)	ES2217533T3 (de)
NO (1)	NO984263L (de)
NZ (1)	NZ331769A (de)
WO (1)	WO1998031684A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19939044A1 (de) *	1999-08-18	2001-03-15	Gruenenthal Gmbh	Verwendung von Morphinanderivaten als Arzneimittel
DE60039444D1 (de) *	1999-08-24	2008-08-21	Toray Industries	Heilmittel für neuropathischen schmerz und versuchstier-modelle des neuropathischen schmerzes
WO2002089729A2 (en)	2001-05-04	2002-11-14	Tularik Inc.	Fused heterocyclic compounds
US6809104B2 (en)	2001-05-04	2004-10-26	Tularik Inc.	Fused heterocyclic compounds
WO2004043958A1 (en)	2002-11-06	2004-05-27	Amgen Inc.	Fused heterocyclic compounds
US20100172909A1 (en) *	2005-10-24	2010-07-08	Masahiro Nishibori	Cerebral edema suppressant
WO2011009020A2 (en)	2009-07-16	2011-01-20	Mallinckrodt Inc.	Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
WO2016167318A1 (ja) *	2015-04-16	2016-10-20	学校法人北里研究所	記憶改善剤及びその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4680172A (en) *	1985-03-05	1987-07-14	Ciba-Geigy Corporation	Devices and methods for treating memory impairment
US4816586A (en) *	1987-07-29	1989-03-28	Regents Of The University Of Minnesota	Delta opioid receptor antagonists
JPH03218313A (ja) *	1989-11-22	1991-09-25	Toray Ind Inc	脳細胞保護剤
JP2906654B2 (ja) *	1989-11-28	1999-06-21	東レ株式会社	免疫抑制剤及びその製造方法
US5223507A (en) *	1992-01-21	1993-06-29	G. D. Searle & Co.	Method of using opioid compounds as delta opioid selective agonist analgesics
US5225417A (en) *	1992-01-21	1993-07-06	G. D. Searle & Co.	Opioid agonist compounds
US5852030A (en) *	1992-09-29	1998-12-22	Toray Industries, Inc.	Indole derivatives, process for producing the same and medicinal uses of the same
JP3605825B2 (ja) *	1992-09-29	2004-12-22	東レ株式会社	インドール誘導体，その製造方法およびその医薬用途
CA2130457A1 (en) *	1992-12-22	1994-07-07	Hiroshi Nagase	Antitussive
EP0661283B1 (de) *	1993-07-19	1998-10-21	Toray Industries, Inc.	Wirkstoff zum schutze von gehirnzellen
EP0663401B1 (de) *	1993-07-23	2000-06-07	Toray Industries, Inc.	Morphinan-derivate und ihre medizinische verwendung
SE9401727D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds I
SE9401728D0 (sv) *	1994-05-18	1994-05-18	Astra Ab	New compounds II

1998
- 1998-01-13 EP EP98900228A patent/EP0894799B1/de not_active Expired - Lifetime
- 1998-01-13 CN CN98800291A patent/CN1117754C/zh not_active Expired - Fee Related
- 1998-01-13 ES ES98900228T patent/ES2217533T3/es not_active Expired - Lifetime
- 1998-01-13 JP JP53410198A patent/JP4110579B2/ja not_active Expired - Fee Related
- 1998-01-13 DE DE69822937T patent/DE69822937T2/de not_active Expired - Fee Related
- 1998-01-13 WO PCT/JP1998/000092 patent/WO1998031684A1/ja not_active Ceased
- 1998-01-13 AU AU53437/98A patent/AU739367B2/en not_active Ceased
- 1998-01-13 NZ NZ331769A patent/NZ331769A/xx unknown
- 1998-01-13 US US09/142,794 patent/US6156762A/en not_active Expired - Fee Related
- 1998-01-13 KR KR1019980707314A patent/KR100557804B1/ko not_active Expired - Fee Related
- 1998-01-13 AT AT98900228T patent/ATE263769T1/de not_active IP Right Cessation
- 1998-09-15 NO NO984263A patent/NO984263L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0894799A4 (de)	2001-08-16
AU739367B2 (en)	2001-10-11
CN1117754C (zh)	2003-08-13
EP0894799B1 (de)	2004-04-07
ATE263769T1 (de)	2004-04-15
US6156762A (en)	2000-12-05
DE69822937T2 (de)	2004-08-12
NO984263D0 (no)	1998-09-15
ES2217533T3 (es)	2004-11-01
NZ331769A (en)	2000-05-26
WO1998031684A1 (en)	1998-07-23
JP4110579B2 (ja)	2008-07-02
AU5343798A (en)	1998-08-07
KR20000064618A (ko)	2000-11-06
EP0894799A1 (de)	1999-02-03
DE69822937D1 (de)	2004-05-13
CN1220668A (zh)	1999-06-23
KR100557804B1 (ko)	2006-06-20

Legal Events

Date	Code	Title	Description
2004-12-06	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
ATE227293T1 (de)	2002-11-15	2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one
PT1259489E (pt)	2006-08-31	Compostos azapoliciclicos condensados con arilo.
EA200000592A1 (ru)	2000-12-25	Азаполициклические соединения, конденсированные с арилом
CA2335285A1 (en)	1999-12-23	Bicyclic piperidine and piperazine compounds having 5-ht6 receptor affinity
FI935529A0 (fi)	1993-12-09	Aminometylensubstituerade icke-aromatiska heterocykliska foereningar
NO306464B1 (no)	1999-11-08	Benzimidazolforbindelser, farmasöytiske preparater som omfatter slike forbindelser, samt anvendelse av forbindelsene for fremstilling av medikamenter
FR2723091B1 (fr)	1996-11-08	Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
ATE272398T1 (de)	2004-08-15	Verwendung von ep4 rezeptorliganden zur behandlung von neuropathischen schmerz
IL106670A0 (en)	1993-12-08	Substituted benzylamino nitrogen containing non-aromatic heterocycles
EP0915094A4 (de)	2004-09-22	Morphinanderivate und ihre medizinische Anwendung
DE69920923D1 (de)	2004-11-11	Anthranilsäurederivate
NO972726D0 (no)	1997-06-13	Tricykliske forbindelser
DE69834500D1 (de)	2006-06-14	Xanthinderivative zur behandlung von hirnischämie
NO984263D0 (no)	1998-09-15	Indolomorfinan-derivat og middel for herding og forebygging av cerebral forstyrrelse
ATE243209T1 (de)	2003-07-15	Tetrahydro gamma-carboline
EP0604354A3 (de)	1995-02-08	Antidepressiv und gegen die Parkinsonsche Krankheit wirkende Verbindungen.
AU8998298A (en)	1999-04-12	Compounds having (2.2.1)bicyclo skeleton
ES2103374T3 (es)	1997-09-16	Derivados de carboxamido-(1,2n)-carbociclo-2-aminotetralina.
FI935799A0 (fi)	1993-12-22	Arylsubstituerade heterocykliska foereningar
DK0648762T3 (da)	2001-07-30	Bicykliske forbindelser som excitatoriske aminosyrereceptorantagonister
CA2256336A1 (en)	1998-10-08	Quinolinomorphinan derivative and medical use thereof
CA2249240A1 (en)	1998-07-23	Indolomorphinan derivative and agent for curing and preventing cerebral disorder
DE3663947D1 (en)	1989-07-20	New indole derivatives, the production and uses thereof
FI842533A0 (fi)	1984-06-21	Hexahydropyrrolo/2,1-a/isokinolin- derivat.
ATE252546T1 (de)	2003-11-15	3-(3-hydroxyphenyl)-3-amino-propionamidderivate