ATE268901T1 - Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen - Google Patents

Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen

Info

Publication number
ATE268901T1
ATE268901T1 AT00911667T AT00911667T ATE268901T1 AT E268901 T1 ATE268901 T1 AT E268901T1 AT 00911667 T AT00911667 T AT 00911667T AT 00911667 T AT00911667 T AT 00911667T AT E268901 T1 ATE268901 T1 AT E268901T1
Authority
AT
Austria
Prior art keywords
optical coherence
rapid
biological functions
coherence microscope
vivo visualization
Prior art date
Application number
AT00911667T
Other languages
English (en)
Inventor
June Iris Medford
Richard Campbell Haskell
Barbara Maria Hoeling
Daniel Carl Petersen
Ruye Wang
Mary Elizabeth Williams
Original Assignee
June Iris Medford
Richard Campbell Haskell
Barbara Maria Hoeling
Daniel Carl Petersen
Ruye Wang
Mary Elizabeth Williams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by June Iris Medford, Richard Campbell Haskell, Barbara Maria Hoeling, Daniel Carl Petersen, Ruye Wang, Mary Elizabeth Williams filed Critical June Iris Medford
Application granted granted Critical
Publication of ATE268901T1 publication Critical patent/ATE268901T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/04—Measuring microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24—Coupling light guides
    • G02B6/26—Optical coupling means
    • G02B6/28—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
    • G02B6/293—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means
    • G02B6/29346—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means operating by wave or beam interference
    • G02B6/29349—Michelson or Michelson/Gires-Tournois configuration, i.e. based on splitting and interferometrically combining relatively delayed signals at a single beamsplitter

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT00911667T 1999-01-29 2000-01-28 Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen ATE268901T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11796399P 1999-01-29 1999-01-29
PCT/US2000/002313 WO2000045153A1 (en) 1999-01-29 2000-01-28 Optical coherence microscope and methods of use for rapid in vivo three-dimensional visualization of biological function

Publications (1)

Publication Number Publication Date
ATE268901T1 true ATE268901T1 (de) 2004-06-15

Family

ID=22375773

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00911667T ATE268901T1 (de) 1999-01-29 2000-01-28 Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen

Country Status (8)

Country Link
US (1) US6608717B1 (de)
EP (1) EP1147398B1 (de)
AT (1) ATE268901T1 (de)
AU (1) AU779717B2 (de)
CA (1) CA2361195A1 (de)
DE (1) DE60011389T2 (de)
ES (1) ES2222183T3 (de)
WO (1) WO2000045153A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7123364B2 (en) * 1998-02-25 2006-10-17 Battelle Energy Alliance, Llc Acoustic imaging microscope
EP1221034B1 (de) * 1999-09-14 2013-05-22 The Research Foundation of State University of New York Verfahren und vorrichtung zur abbildung der dynamik eines streuenden mediums
US6795195B1 (en) * 1999-09-14 2004-09-21 Research Foundation Of State University Of New York System and method for tomographic imaging of dynamic properties of a scattering medium
EP1311801B1 (de) * 2000-07-07 2005-09-14 Robert Bosch Gmbh Interferometrische, kurzkohärente formmessvorrichtung für mehrere flächen ( ventilsitz ) durch mehrere referenzebenen
DE10042751A1 (de) * 2000-08-31 2002-03-14 Thomas Hellmuth System zur berührungslosen Vermessung der optischen Abbildungsqualität eines Auges
ATE437350T1 (de) * 2000-10-31 2009-08-15 Univ Danmarks Tekniske Optische verstärkung bei der kohärenten optischen frequenzmodulierten dauer-reflektometrie
WO2002059562A2 (en) * 2001-01-26 2002-08-01 Colorado State University Research Foundation Analysis of gene expression and biological function using optical imaging
FR2834567B1 (fr) * 2002-01-07 2004-03-19 Centre Nat Rech Scient Procede et dispositif de visualisation microscopique a sondes locales d'un objet tridimensionnel
US7379168B2 (en) * 2002-07-09 2008-05-27 Luna Innovations Incorporated Polarization diversity detection without a polarizing beam splitter
WO2004025379A2 (en) * 2002-09-12 2004-03-25 Nline Corporation Optical acquisition systems for direct-to-digital holography and holovision
US7369234B2 (en) * 2003-02-03 2008-05-06 Rudolph Technologies, Inc. Method of performing optical measurement on a sample
US7474407B2 (en) * 2003-02-20 2009-01-06 Applied Science Innovations Optical coherence tomography with 3d coherence scanning
US7263394B2 (en) * 2003-06-04 2007-08-28 Tomophase Corporation Coherence-gated optical glucose monitor
US6943881B2 (en) * 2003-06-04 2005-09-13 Tomophase Corporation Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
US7256894B2 (en) * 2003-10-20 2007-08-14 The Regents Of The University Of California Method and apparatus for performing second harmonic optical coherence tomography
JP3860162B2 (ja) * 2003-10-20 2006-12-20 大塚電子株式会社 位相変調型干渉法を用いた動的光散乱測定装置
ATE449319T1 (de) * 2004-08-11 2009-12-15 Max Planck Gesellschaft Verfahren und vorrichtung zur messung von wellenfronten
US8498681B2 (en) * 2004-10-05 2013-07-30 Tomophase Corporation Cross-sectional mapping of spectral absorbance features
US7970458B2 (en) * 2004-10-12 2011-06-28 Tomophase Corporation Integrated disease diagnosis and treatment system
US7388672B2 (en) * 2004-11-19 2008-06-17 Carl Ziess Meditec, Inc. High efficiency balanced detection interferometer
US7831298B1 (en) 2005-10-04 2010-11-09 Tomophase Corporation Mapping physiological functions of tissues in lungs and other organs
US20070265521A1 (en) * 2006-05-15 2007-11-15 Thomas Redel Integrated MRI and OCT system and dedicated workflow for planning, online guiding and monitoring of interventions using MRI in combination with OCT
WO2008063587A1 (en) 2006-11-20 2008-05-29 Grassroots Biotechnology Plant growth and imaging devices and related methods and computer program products
US8217992B2 (en) * 2007-01-11 2012-07-10 The Jackson Laboratory Microscopic imaging techniques
EP1962082A1 (de) * 2007-02-21 2008-08-27 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
ATE474205T1 (de) * 2007-02-21 2010-07-15 Agfa Healthcare Nv System und verfahren zur optischen kohärenztomographie
EP1962050B1 (de) 2007-02-21 2015-12-23 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie sowie Verfahren zur Kalibrierung eines solchen Systems
EP1962081B1 (de) * 2007-02-21 2016-09-14 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962049B1 (de) * 2007-02-21 2015-12-23 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP1962079B1 (de) * 2007-02-21 2016-06-01 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP2365316B1 (de) * 2007-02-21 2014-10-22 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962051A1 (de) * 2007-02-21 2008-08-27 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
WO2008106540A2 (en) * 2007-02-27 2008-09-04 The Texas A & M University System Short-wavelength coherence tomography
US7706646B2 (en) 2007-04-24 2010-04-27 Tomophase Corporation Delivering light via optical waveguide and multi-view optical probe head
EP2002784B1 (de) * 2007-06-11 2018-07-11 Canon Kabushiki Kaisha Bildgebungsgerät für intravitale Informationen
DE102007029822B4 (de) * 2007-06-28 2010-01-07 Siemens Ag Interferometer
WO2009108950A2 (en) * 2008-02-29 2009-09-03 Tomophase Corporation Temperature profile mapping and guided thermotherapy
US7772569B2 (en) * 2008-04-01 2010-08-10 The Jackson Laboratory 3D biplane microscopy
WO2009124569A1 (de) 2008-04-11 2009-10-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optisches kohärenztomographiesystem und optisches kohärenztomographieverfahren
JP2011521747A (ja) 2008-06-02 2011-07-28 ライトラブ イメージング， インコーポレイテッド 光コヒーレンストモグラフィ画像から組織特徴を取得する定量的方法
EP2226003B1 (de) * 2009-03-05 2015-05-06 Brainlab AG Medizintechnische Bildregistrierung mittels optischer Kohärenztomographie
JP5275880B2 (ja) * 2009-04-03 2013-08-28 株式会社トプコン 光画像計測装置
US8467858B2 (en) * 2009-04-29 2013-06-18 Tomophase Corporation Image-guided thermotherapy based on selective tissue thermal treatment
US9189728B2 (en) * 2009-07-23 2015-11-17 I-Property Holding Corp. Method for the authentication of dosage forms
EP2470886A4 (de) 2009-08-26 2016-11-02 Tomophase Inc Optische gewebeabbildung auf basis optischer frequenzdomänenabbildung
CN102792151B (zh) 2010-03-23 2015-11-25 加州理工学院 用于2d和3d成像的超分辨率光流体显微镜
US9643184B2 (en) 2010-10-26 2017-05-09 California Institute Of Technology e-Petri dishes, devices, and systems having a light detector for sampling a sequence of sub-pixel shifted projection images
US9569664B2 (en) * 2010-10-26 2017-02-14 California Institute Of Technology Methods for rapid distinction between debris and growing cells
US9426429B2 (en) 2010-10-26 2016-08-23 California Institute Of Technology Scanning projective lensless microscope system
EP2681601A4 (de) 2011-03-03 2014-07-23 California Inst Of Techn Lichtleiterpixel
EP2816388A4 (de) * 2012-02-15 2015-07-22 Olympus Corp Laserabtastende betrachtungsvorrichtung
JP6338955B2 (ja) * 2014-07-18 2018-06-06 株式会社日立ハイテクノロジーズ 細胞培養装置および画像解析装置
US9940723B2 (en) 2014-12-12 2018-04-10 Lightlab Imaging, Inc. Systems and methods to detect and display endovascular features
US10565774B2 (en) * 2015-09-03 2020-02-18 Siemens Healthcare Gmbh Visualization of surface-volume hybrid models in medical imaging
EP3538941B1 (de) 2016-11-10 2025-04-23 The Trustees of Columbia University in the City of New York Schnelles hochauflösendes bildgebungsverfahren für grosse proben
US10588514B1 (en) * 2019-04-29 2020-03-17 Hua Shang Vivo photon analysis system and method
CN110824688A (zh) * 2019-10-12 2020-02-21 江苏大学 一种基于相位成像生物细胞亚表面形态快速重建方法
JP7491142B2 (ja) * 2020-08-27 2024-05-28 セイコーエプソン株式会社 レーザー干渉計およびレーザー干渉計の制御方法
JP7533024B2 (ja) * 2020-08-27 2024-08-14 セイコーエプソン株式会社 レーザー干渉計
CN112577418B (zh) * 2020-11-26 2022-09-20 湖北爱默思智能检测装备有限公司 一种正交偏振分选光学采集装置及其应用
WO2025006004A1 (en) * 2023-06-26 2025-01-02 Conceivable Life Sciences Inc. Intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform background
US12270646B2 (en) * 2022-08-23 2025-04-08 University Of Rochester Broadband interferometric confocal microscope
US12226125B2 (en) 2023-06-26 2025-02-18 Conceivable Life Sciences Inc. Autonomous vitrification in an intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321501A (en) 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US5570182A (en) * 1994-05-27 1996-10-29 Regents Of The University Of California Method for detection of dental caries and periodontal disease using optical imaging
WO1995033970A1 (en) * 1994-06-02 1995-12-14 Massachusetts Institute Of Technology Rotating cam for optical systems

Also Published As

Publication number Publication date
AU779717B2 (en) 2005-02-10
CA2361195A1 (en) 2000-08-03
EP1147398B1 (de) 2004-06-09
WO2000045153A9 (en) 2001-09-27
AU3352900A (en) 2000-08-18
ES2222183T3 (es) 2005-02-01
WO2000045153A1 (en) 2000-08-03
EP1147398A1 (de) 2001-10-24
DE60011389D1 (de) 2004-07-15
US6608717B1 (en) 2003-08-19
DE60011389T2 (de) 2005-06-09

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