ATE268901T1 - Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen - Google Patents

Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen

Info

Publication number
ATE268901T1
ATE268901T1 AT00911667T AT00911667T ATE268901T1 AT E268901 T1 ATE268901 T1 AT E268901T1 AT 00911667 T AT00911667 T AT 00911667T AT 00911667 T AT00911667 T AT 00911667T AT E268901 T1 ATE268901 T1 AT E268901T1
Authority
AT
Austria
Prior art keywords
optical coherence
rapid
biological functions
coherence microscope
vivo visualization
Prior art date
Application number
AT00911667T
Other languages
English (en)
Inventor
June Iris Medford
Richard Campbell Haskell
Barbara Maria Hoeling
Daniel Carl Petersen
Ruye Wang
Mary Elizabeth Williams
Original Assignee
June Iris Medford
Richard Campbell Haskell
Barbara Maria Hoeling
Daniel Carl Petersen
Ruye Wang
Mary Elizabeth Williams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by June Iris Medford, Richard Campbell Haskell, Barbara Maria Hoeling, Daniel Carl Petersen, Ruye Wang, Mary Elizabeth Williams filed Critical June Iris Medford
Application granted granted Critical
Publication of ATE268901T1 publication Critical patent/ATE268901T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/04—Measuring microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24—Coupling light guides
    • G02B6/26—Optical coupling means
    • G02B6/28—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
    • G02B6/293—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means
    • G02B6/29346—Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means operating by wave or beam interference
    • G02B6/29349—Michelson or Michelson/Gires-Tournois configuration, i.e. based on splitting and interferometrically combining relatively delayed signals at a single beamsplitter

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT00911667T 1999-01-29 2000-01-28 Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen ATE268901T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11796399P 1999-01-29 1999-01-29
PCT/US2000/002313 WO2000045153A1 (en) 1999-01-29 2000-01-28 Optical coherence microscope and methods of use for rapid in vivo three-dimensional visualization of biological function

Publications (1)

Publication Number Publication Date
ATE268901T1 true ATE268901T1 (de) 2004-06-15

Family

ID=22375773

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00911667T ATE268901T1 (de) 1999-01-29 2000-01-28 Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen

Country Status (8)

Country Link
US (1) US6608717B1 (de)
EP (1) EP1147398B1 (de)
AT (1) ATE268901T1 (de)
AU (1) AU779717B2 (de)
CA (1) CA2361195A1 (de)
DE (1) DE60011389T2 (de)
ES (1) ES2222183T3 (de)
WO (1) WO2000045153A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7123364B2 (en) * 1998-02-25 2006-10-17 Battelle Energy Alliance, Llc Acoustic imaging microscope
US6795195B1 (en) * 1999-09-14 2004-09-21 Research Foundation Of State University Of New York System and method for tomographic imaging of dynamic properties of a scattering medium
AU7579300A (en) * 1999-09-14 2001-04-17 Research Foundation of State University of New York, Technology Transfer Office, The Method and system for imaging the dynamics of scattering medium
WO2002004889A1 (de) * 2000-07-07 2002-01-17 Robert Bosch Gmbh Interferometrische, kurzkohärente formmessvorrichtung für mehrere flächen (ventilsitz) durch mehrere referenzebenen
DE10042751A1 (de) * 2000-08-31 2002-03-14 Thomas Hellmuth System zur berührungslosen Vermessung der optischen Abbildungsqualität eines Auges
AU2002212105B2 (en) 2000-10-31 2006-06-08 Danmarks Tekniske Universitet Optical amplification in coherent optical frequency modulated continuous wave reflectometry
WO2002059562A2 (en) * 2001-01-26 2002-08-01 Colorado State University Research Foundation Analysis of gene expression and biological function using optical imaging
FR2834567B1 (fr) * 2002-01-07 2004-03-19 Centre Nat Rech Scient Procede et dispositif de visualisation microscopique a sondes locales d'un objet tridimensionnel
WO2004005973A2 (en) * 2002-07-09 2004-01-15 Luna Technologies Polarization diversity detection without a polarizing beam splitter
WO2004025379A2 (en) * 2002-09-12 2004-03-25 Nline Corporation Optical acquisition systems for direct-to-digital holography and holovision
US7369234B2 (en) * 2003-02-03 2008-05-06 Rudolph Technologies, Inc. Method of performing optical measurement on a sample
WO2004073501A2 (en) * 2003-02-20 2004-09-02 Gutin Mikhail Optical coherence tomography with 3d coherence scanning
US6943881B2 (en) * 2003-06-04 2005-09-13 Tomophase Corporation Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
US7263394B2 (en) * 2003-06-04 2007-08-28 Tomophase Corporation Coherence-gated optical glucose monitor
US7256894B2 (en) * 2003-10-20 2007-08-14 The Regents Of The University Of California Method and apparatus for performing second harmonic optical coherence tomography
JP3860162B2 (ja) * 2003-10-20 2006-12-20 大塚電子株式会社 位相変調型干渉法を用いた動的光散乱測定装置
ATE449319T1 (de) * 2004-08-11 2009-12-15 Max Planck Gesellschaft Verfahren und vorrichtung zur messung von wellenfronten
US8498681B2 (en) * 2004-10-05 2013-07-30 Tomophase Corporation Cross-sectional mapping of spectral absorbance features
US7970458B2 (en) * 2004-10-12 2011-06-28 Tomophase Corporation Integrated disease diagnosis and treatment system
US7388672B2 (en) * 2004-11-19 2008-06-17 Carl Ziess Meditec, Inc. High efficiency balanced detection interferometer
US7831298B1 (en) 2005-10-04 2010-11-09 Tomophase Corporation Mapping physiological functions of tissues in lungs and other organs
US20070265521A1 (en) * 2006-05-15 2007-11-15 Thomas Redel Integrated MRI and OCT system and dedicated workflow for planning, online guiding and monitoring of interventions using MRI in combination with OCT
CA2670273C (en) * 2006-11-20 2016-04-05 Grassroots Biotechnology, Inc. Plant growth and imaging devices and related methods and computer program products
US8217992B2 (en) * 2007-01-11 2012-07-10 The Jackson Laboratory Microscopic imaging techniques
EP1962079B1 (de) * 2007-02-21 2016-06-01 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
DE502007004384D1 (de) * 2007-02-21 2010-08-26 Agfa Healthcare Nv System und Verfahren zur optischen Kohärenztomographie
EP1962049B1 (de) * 2007-02-21 2015-12-23 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP2267403A3 (de) * 2007-02-21 2011-04-20 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP2339329A3 (de) * 2007-02-21 2012-04-04 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
EP1962080B1 (de) * 2007-02-21 2011-06-01 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962081B1 (de) * 2007-02-21 2016-09-14 Agfa HealthCare N.V. System zur optischen Kohärenztomographie
EP1962051A1 (de) * 2007-02-21 2008-08-27 Agfa HealthCare N.V. System und Verfahren zur optischen Kohärenztomographie
US7656538B2 (en) * 2007-02-27 2010-02-02 The Texas A&M University System Short-wavelength coherence tomography
US7706646B2 (en) * 2007-04-24 2010-04-27 Tomophase Corporation Delivering light via optical waveguide and multi-view optical probe head
EP2002784B1 (de) * 2007-06-11 2018-07-11 Canon Kabushiki Kaisha Bildgebungsgerät für intravitale Informationen
DE102007029822B4 (de) * 2007-06-28 2010-01-07 Siemens Ag Interferometer
WO2009108950A2 (en) * 2008-02-29 2009-09-03 Tomophase Corporation Temperature profile mapping and guided thermotherapy
US7772569B2 (en) * 2008-04-01 2010-08-10 The Jackson Laboratory 3D biplane microscopy
WO2009124569A1 (de) 2008-04-11 2009-10-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optisches kohärenztomographiesystem und optisches kohärenztomographieverfahren
EP2293714B1 (de) 2008-06-02 2014-08-13 Lightlab Imaging, Inc. Quantitative verfahren zur erfassung von gewebekennwerten auf bildern aus einer optischen kohärenztomographie
EP2226003B1 (de) * 2009-03-05 2015-05-06 Brainlab AG Medizintechnische Bildregistrierung mittels optischer Kohärenztomographie
JP5275880B2 (ja) * 2009-04-03 2013-08-28 株式会社トプコン 光画像計測装置
US8467858B2 (en) * 2009-04-29 2013-06-18 Tomophase Corporation Image-guided thermotherapy based on selective tissue thermal treatment
US9189728B2 (en) * 2009-07-23 2015-11-17 I-Property Holding Corp. Method for the authentication of dosage forms
EP2470886A4 (de) 2009-08-26 2016-11-02 Tomophase Inc Optische gewebeabbildung auf basis optischer frequenzdomänenabbildung
EP2550522B1 (de) 2010-03-23 2016-11-02 California Institute of Technology Hochauflösende optofluidische mikroskope für 2d- und 3d-bildgebung
WO2012058233A2 (en) 2010-10-26 2012-05-03 California Institute Of Technology Scanning projective lensless microscope system
US9569664B2 (en) * 2010-10-26 2017-02-14 California Institute Of Technology Methods for rapid distinction between debris and growing cells
US9643184B2 (en) 2010-10-26 2017-05-09 California Institute Of Technology e-Petri dishes, devices, and systems having a light detector for sampling a sequence of sub-pixel shifted projection images
WO2012119094A2 (en) 2011-03-03 2012-09-07 California Institute Of Technology Light guided pixel
EP2816388A4 (de) * 2012-02-15 2015-07-22 Olympus Corp Laserabtastende betrachtungsvorrichtung
JP6338955B2 (ja) * 2014-07-18 2018-06-06 株式会社日立ハイテクノロジーズ 細胞培養装置および画像解析装置
EP3838124A1 (de) 2014-12-12 2021-06-23 Lightlab Imaging, Inc. Systeme zur detektion und anzeige endovaskulärer merkmale
US10565774B2 (en) * 2015-09-03 2020-02-18 Siemens Healthcare Gmbh Visualization of surface-volume hybrid models in medical imaging
EP3538941B1 (de) 2016-11-10 2025-04-23 The Trustees of Columbia University in the City of New York Schnelles hochauflösendes bildgebungsverfahren für grosse proben
US10588514B1 (en) * 2019-04-29 2020-03-17 Hua Shang Vivo photon analysis system and method
CN110824688A (zh) * 2019-10-12 2020-02-21 江苏大学 一种基于相位成像生物细胞亚表面形态快速重建方法
JP7533024B2 (ja) * 2020-08-27 2024-08-14 セイコーエプソン株式会社 レーザー干渉計
JP7491142B2 (ja) * 2020-08-27 2024-05-28 セイコーエプソン株式会社 レーザー干渉計およびレーザー干渉計の制御方法
CN112577418B (zh) * 2020-11-26 2022-09-20 湖北爱默思智能检测装备有限公司 一种正交偏振分选光学采集装置及其应用
WO2025006004A1 (en) * 2023-06-26 2025-01-02 Conceivable Life Sciences Inc. Intelligent automated in vitro fertilization and intracytoplasmic sperm injection platform background
US12270646B2 (en) * 2022-08-23 2025-04-08 University Of Rochester Broadband interferometric confocal microscope
EP4731105A1 (de) 2023-06-26 2026-04-29 Conceivable Life Sciences, Inc. Intelligente automatisierte in-vitro-befruchtung und hintergrund einer intrazytoplasmischen spermainjektionsplattform

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321501A (en) 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US5570182A (en) * 1994-05-27 1996-10-29 Regents Of The University Of California Method for detection of dental caries and periodontal disease using optical imaging
WO1995033970A1 (en) * 1994-06-02 1995-12-14 Massachusetts Institute Of Technology Rotating cam for optical systems

Also Published As

Publication number Publication date
AU779717B2 (en) 2005-02-10
EP1147398A1 (de) 2001-10-24
CA2361195A1 (en) 2000-08-03
WO2000045153A1 (en) 2000-08-03
ES2222183T3 (es) 2005-02-01
WO2000045153A9 (en) 2001-09-27
AU3352900A (en) 2000-08-18
EP1147398B1 (de) 2004-06-09
DE60011389T2 (de) 2005-06-09
US6608717B1 (en) 2003-08-19
DE60011389D1 (de) 2004-07-15

Similar Documents

Publication Publication Date Title
ATE268901T1 (de) Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen
DE50214827D1 (de) Verfahren und Anordnung zur tiefenaufgelösten optischen Erfassung einer Probe
EP1154242A3 (de) Optischer Kodierer
NO973542L (no) Kontrastmedier for in vivo billeddannelse basert på lystransmisjon ved refleksjon
DE69920170D1 (de) Vorrichtung und verfahren zur modulation von gewebe
EP1269917A4 (de) Gerät und verfahren zur messung von biologischen informationen
EP1069600A4 (de) Belichtungsvorrichtung und -verfahren, und herstellungsverfahren einer solchen vorrichtung
EP1225432A3 (de) Wellenlängenkontrollgerät
FI901417A0 (fi) Foerfarande foer undersoekning av ytstruktur.
EP1393115A4 (de) Systeme und verfahren zum scannen einer probe mit einem lichtstrahl
ATE153777T1 (de) Optischer modulator
IL139958A0 (en) Method and device for opto-electrical acquisition of shapes by axial ellumination
DE69600033D1 (de) Verfahren zur Verwaltung eines optischen Ringes mit Wellenlängenmultiplex
ATE484765T1 (de) Vorrichtung und verfahren zur messung optischer eigenschaften eines objekts
DE69317874D1 (de) Verfahren und vorrichtung zur differentiellen messung von brechungsindizes und deren anwendung
DE50202406D1 (de) Verfahren zum Betreiben einer Lasergravureinrichtung
ATE475080T1 (de) Refraktometer und verfahren zur messung des brechungsindexes
DE69916598D1 (de) Vorrichtung zur breitbandigen diffraktiven streuung und assoziierte verfahren
DE60304222D1 (de) VERFAHREN ZUR MESSUNG VON KONTURVERuNDERUNGEN
ATE456022T1 (de) Verfahren zur interferenzmessung und vorrichtung zur interferenzmessung
DE69521382D1 (de) Gerät zur verstärkung der modulationsamplitude eines optischen strahls
EP0953863A3 (de) Modulator für analoge Anwendungen
DE59402236D1 (de) Lichtwellenleiter für faseroptische verstärker für den wellenlängenbereich um 1300 nm
DE69027514D1 (de) Optisches Gerät zur Detektion der Modulation eines Lichtstrahls
JPH10253531A5 (de)

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1147398

Country of ref document: EP

REN Ceased due to non-payment of the annual fee