ATE269340T1 - Thiazolopyrimidine und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität - Google Patents

Thiazolopyrimidine und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität

Info

Publication number
ATE269340T1
ATE269340T1 AT01906447T AT01906447T ATE269340T1 AT E269340 T1 ATE269340 T1 AT E269340T1 AT 01906447 T AT01906447 T AT 01906447T AT 01906447 T AT01906447 T AT 01906447T AT E269340 T1 ATE269340 T1 AT E269340T1
Authority
AT
Austria
Prior art keywords
thiazolopyrimidines
modulators
chemokine receptor
receptor activity
compounds
Prior art date
Application number
AT01906447T
Other languages
English (en)
Inventor
Roger Bonnert
Peter Cage
Fraser Hunt
Robert Jewell
Iain Walters
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE269340T1 publication Critical patent/ATE269340T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01906447T 2000-02-11 2001-02-07 Thiazolopyrimidine und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität ATE269340T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0003025A GB2359081A (en) 2000-02-11 2000-02-11 Pharmaceutically active thiazolopyrimidines
PCT/SE2001/000247 WO2001058907A1 (en) 2000-02-11 2001-02-07 Thiazolopyrimidines and their use as modulators of chemokine receptor activity

Publications (1)

Publication Number Publication Date
ATE269340T1 true ATE269340T1 (de) 2004-07-15

Family

ID=9885290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906447T ATE269340T1 (de) 2000-02-11 2001-02-07 Thiazolopyrimidine und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität

Country Status (8)

Country Link
US (1) US6958343B2 (de)
EP (1) EP1257556B1 (de)
JP (1) JP2003522192A (de)
AT (1) ATE269340T1 (de)
AU (1) AU2001234273A1 (de)
DE (1) DE60103856T2 (de)
GB (1) GB2359081A (de)
WO (1) WO2001058907A1 (de)

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JP2003522191A (ja) * 2000-02-11 2003-07-22 アストラゼネカ・アクチエボラーグ ケモカイン受容体活性のモジュレーターとしてのピリミジン化合物およびそれらの使用
GB2359078A (en) * 2000-02-11 2001-08-15 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
GB2359551A (en) * 2000-02-23 2001-08-29 Astrazeneca Uk Ltd Pharmaceutically active pyrimidine derivatives
SE0003828D0 (sv) 2000-10-20 2000-10-20 Astrazeneca Ab Novel compounds
SE0101082D0 (sv) 2001-03-27 2001-03-27 Astrazeneca Ab Novel use
SE0101322D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab Novel compounds
SE0102716D0 (sv) * 2001-08-14 2001-08-14 Astrazeneca Ab Novel compounds
DE60304718T2 (de) 2002-08-06 2007-04-26 Astrazeneca Ab Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität
GB0221828D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0221829D0 (en) * 2002-09-20 2002-10-30 Astrazeneca Ab Novel compound
GB0328243D0 (en) * 2003-12-05 2004-01-07 Astrazeneca Ab Methods
AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) * 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
TW200820973A (en) 2006-09-29 2008-05-16 Astrazeneca Ab Novel compounds 480
EP2069365A4 (de) * 2006-09-29 2011-11-02 Astrazeneca Ab Neue 5,7, 7-disubstituierte [1, 3]thiazolo [4, 5-d]pyrimidin-2 (3h)-amin-derivate und ihre verwendung in der therapie
EP2432776B1 (de) * 2009-05-21 2019-09-11 Universite Laval Methyl-sulfanyl-pyrimidine als entzündungshemmende mittel, schmerzmittel und antiepileptika

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Also Published As

Publication number Publication date
EP1257556A1 (de) 2002-11-20
JP2003522192A (ja) 2003-07-22
US20030032642A1 (en) 2003-02-13
DE60103856D1 (de) 2004-07-22
AU2001234273A1 (en) 2001-08-20
US6958343B2 (en) 2005-10-25
DE60103856T2 (de) 2005-07-14
GB2359081A (en) 2001-08-15
WO2001058907A1 (en) 2001-08-16
EP1257556B1 (de) 2004-06-16
GB0003025D0 (en) 2000-03-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties