ATE323702T1 - Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität - Google Patents
Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivitätInfo
- Publication number
- ATE323702T1 ATE323702T1 AT03766443T AT03766443T ATE323702T1 AT E323702 T1 ATE323702 T1 AT E323702T1 AT 03766443 T AT03766443 T AT 03766443T AT 03766443 T AT03766443 T AT 03766443T AT E323702 T1 ATE323702 T1 AT E323702T1
- Authority
- AT
- Austria
- Prior art keywords
- tie2
- tek
- pyrimidines
- activity
- condensed pyridines
- Prior art date
Links
- 102100022014 Angiopoietin-1 receptor Human genes 0.000 title 2
- 101000753291 Homo sapiens Angiopoietin-1 receptor Proteins 0.000 title 2
- RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0218168A GB0218168D0 (en) | 2002-08-06 | 2002-08-06 | Compounds |
| GB0312356A GB0312356D0 (en) | 2003-05-30 | 2003-05-30 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE323702T1 true ATE323702T1 (de) | 2006-05-15 |
Family
ID=31497259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03766443T ATE323702T1 (de) | 2002-08-06 | 2003-08-01 | Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7427616B2 (de) |
| EP (1) | EP1537112B1 (de) |
| JP (1) | JP2005538118A (de) |
| KR (1) | KR20050067383A (de) |
| AR (1) | AR041189A1 (de) |
| AT (1) | ATE323702T1 (de) |
| AU (1) | AU2003246972A1 (de) |
| BR (1) | BR0313078A (de) |
| CA (1) | CA2494421A1 (de) |
| DE (1) | DE60304718T2 (de) |
| IL (1) | IL166521A0 (de) |
| MX (1) | MXPA05001389A (de) |
| NO (1) | NO20050418L (de) |
| TW (1) | TW200407116A (de) |
| WO (1) | WO2004013141A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0230089D0 (en) * | 2002-12-24 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
| CA2546192C (en) | 2003-11-17 | 2010-04-06 | Pfizer Products Inc. | Pyrrolopyrimidine compounds useful in treatment of cancer |
| TWI332003B (en) | 2004-01-30 | 2010-10-21 | Lilly Co Eli | Kinase inhibitors |
| GB0402518D0 (en) * | 2004-02-05 | 2004-03-10 | Astrazeneca Ab | Therapeutic agents |
| CA2551909C (en) * | 2004-02-12 | 2011-10-11 | Transtech Pharma, Inc. | Substituted azole derivatives, compositions, and methods of use |
| CA2565037A1 (en) * | 2004-04-28 | 2005-11-10 | Cv Therapeutics, Inc. | Purine derivatives as a1 adenosine receptor antagonists |
| JP4842929B2 (ja) * | 2004-05-27 | 2011-12-21 | ファイザー・プロダクツ・インク | 癌治療に有用なピロロピリミジン誘導体 |
| KR20070034049A (ko) | 2004-06-09 | 2007-03-27 | 글락소 그룹 리미티드 | 피롤로피리딘 유도체 |
| WO2006019965A2 (en) * | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| JP2008508358A (ja) * | 2004-08-02 | 2008-03-21 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | アリール−アミノ置換ピロロピリミジンマルチキナーゼ阻害化合物 |
| CA2575466A1 (en) | 2004-08-13 | 2006-02-23 | Genentech, Inc. | Thiazole based inhibitors of atp-utilizing enzymes |
| EP1858877B1 (de) | 2005-01-14 | 2014-03-12 | Gilead Connecticut, Inc. | 1,3-substituierte diaryl-harnstoffe als modulatoren von kinase-aktivität |
| EA200870117A1 (ru) * | 2005-12-23 | 2008-12-30 | Смитклайн Бичам Корпорейшн | Азаиндоловые ингибиторы аурора-киназ |
| WO2007124181A2 (en) | 2006-04-21 | 2007-11-01 | Amgen Inc. | Thieno-[2,3-d]pyrimidine and thieno-pyridazine compounds and methods of use |
| WO2008057280A1 (en) | 2006-10-27 | 2008-05-15 | Amgen Inc. | Multi-cyclic compounds and methods of use |
| EP2247596A2 (de) | 2008-01-11 | 2010-11-10 | Natco Pharma Limited | Neuartige pyrazol-[3,4-d-]pyrimidin-derivate als wirkstoffe gegen krebs |
| EP2307456B1 (de) | 2008-06-27 | 2014-10-15 | Amgen Inc. | Die inhibierung von ang-2 zur behandlung multipler sklerose |
| JP2011529061A (ja) | 2008-07-22 | 2011-12-01 | バイオクライスト ファーマシューティカルズ, インコーポレイテッド | 合成中間体およびプロセス |
| TWI720517B (zh) | 2009-01-15 | 2021-03-01 | 美商英塞特公司 | 製造jak抑制劑之方法及相關中間化合物 |
| WO2011018894A1 (en) * | 2009-08-10 | 2011-02-17 | Raqualia Pharma Inc. | Pyrrolopyrimidine derivatives as potassium channel modulators |
| SG183304A1 (en) | 2010-02-17 | 2012-09-27 | Takeda Pharmaceutical | Heterocyclic compound |
| US8859768B2 (en) * | 2010-08-11 | 2014-10-14 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| JP5902172B2 (ja) | 2010-09-08 | 2016-04-13 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 広範囲のインフルエンザ抗ウイルス薬としての新規ピペラジン類似体 |
| BR112013007651A2 (pt) | 2010-09-28 | 2019-09-24 | Bristol-Myers Squibb Company | análogos de piperazina com grupos heteroarila substituídos como antivirais de influenza de amplo espectro |
| JP6218848B2 (ja) * | 2012-11-20 | 2017-10-25 | プロキナーゼ ゲゼルシャフト ミット ベシュレンクテル ハフツング | プロテインキナーゼ阻害剤としてのチオエーテル誘導体 |
| EP2733146A1 (de) * | 2012-11-20 | 2014-05-21 | KTB Tumorforschungsgesellschaft mbH | Thioetherderivate als Proteinkinase-Inhibitoren |
| ES2651367T3 (es) | 2013-07-15 | 2018-01-25 | Basf Se | Compuestos plaguicidas |
| US9758492B2 (en) * | 2013-08-27 | 2017-09-12 | Bristol-Myers Squibb Company | IDO inhibitors |
| US10189853B2 (en) | 2014-12-17 | 2019-01-29 | Duquesne University Of The Holy Spirit | Conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as anti-tumor agents |
| EP3632908A1 (de) | 2018-10-02 | 2020-04-08 | Inventiva | Inhibitoren der yap / taz-tead-interaktion und ihre verwendung bei der behandlung von krebs |
| CN120040470A (zh) * | 2018-11-20 | 2025-05-27 | 乔治敦大学 | 用于治疗神经退行性、肌退行性和溶酶体贮积病症的组合物和方法 |
| EP4553080A1 (de) | 2023-11-07 | 2025-05-14 | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. | Nucleosidderivate als antivirale mittel gegen coronaviren |
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| DD287503A5 (de) | 1988-06-13 | 1991-02-28 | Karl-Marx-Universitaet Leipzig,De | Verfahren zur herstellung von 4-amino-2-mercapto-thieno-/2,3-d/pyrimidinen bzw. 4-amino-2-alkylthio-thieno/2,3-d/-pyrimidinen |
| DE4008726A1 (de) | 1990-03-19 | 1991-09-26 | Basf Ag | Thieno(2,3-d)pyrimidinderivate |
| US5958930A (en) | 1991-04-08 | 1999-09-28 | Duquesne University Of The Holy Ghost | Pyrrolo pyrimidine and furo pyrimidine derivatives |
| US6756388B1 (en) | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| US5589482A (en) | 1994-12-14 | 1996-12-31 | Pfizer Inc. | Benzo-thiophene estrogen agonists to treat prostatic hyperplasia |
| AU6966696A (en) | 1995-10-05 | 1997-04-28 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| AU3176297A (en) | 1996-06-25 | 1998-01-14 | Novartis Ag | Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof |
| WO1998007835A2 (en) | 1996-08-21 | 1998-02-26 | Sugen, Inc. | Crystal structures of a protein tyrosine kinase |
| TR199902301T2 (xx) | 1997-03-19 | 1999-12-21 | Basf Aktiengesellschaft | Pirilo $2,3D]pirimidinler ve onlar�n kullan�m�. |
| EP1028964A1 (de) | 1997-11-11 | 2000-08-23 | Pfizer Products Inc. | Thienopyrimidin- und thienopyridin-derivate als antikrebsmittel |
| EP1077971A1 (de) | 1998-05-14 | 2001-02-28 | G.D. SEARLE & CO. | Substituierte 1,5-diarylpyrazole als p38 kinase inhibitoren |
| AU4231299A (en) | 1998-06-04 | 1999-12-20 | Abbott Laboratories | Cell adhesion-inhibiting antinflammatory compounds |
| SE9802729D0 (sv) | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
| ES2253930T3 (es) | 1998-09-18 | 2006-06-01 | ABBOTT GMBH & CO. KG | 4-aminopirrolopirimidinas como inhibidores de quinasa. |
| ID29028A (id) | 1998-09-18 | 2001-07-26 | Basf Ag | Pirolopirimidina sebagai penghambat protein kinase |
| UA71945C2 (en) | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| CA2367143A1 (en) | 1999-04-02 | 2000-10-12 | Euro-Celtique S.A. | Purine derivatives having phosphodiesterase iv inhibition activity |
| EP1175419B1 (de) | 1999-04-02 | 2003-05-28 | Bristol-Myers Squibb Pharma Company | Arylsulfonyle als faktor xa inhibitoren |
| US6930101B1 (en) | 1999-05-17 | 2005-08-16 | The Regents Of The University Of California | Thiazolopyrimidines useful as TNFα inhibitors |
| WO2000075145A1 (en) | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| CZ2002959A3 (cs) | 1999-09-17 | 2002-07-17 | Millennium Pharmaceuticals, Inc. | Inhibitory faktoru Xa |
| MXPA02002938A (es) | 1999-09-17 | 2004-12-06 | Abbott Gmbh & Co Kg | Inhibidores de cinasa como agentes agentes terapeuticos. |
| US6921763B2 (en) | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| JP2003509428A (ja) | 1999-09-17 | 2003-03-11 | アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー | 治療薬としてのピラゾロピリミジン |
| SE9903544D0 (sv) | 1999-10-01 | 1999-10-01 | Astra Pharma Prod | Novel compounds |
| AU1529901A (en) | 1999-11-22 | 2001-06-04 | Smithkline Beecham Plc | Compounds |
| DE60031886T2 (de) | 1999-12-17 | 2007-09-06 | Ariad Pharmaceuticals, Inc., Cambridge | Purinderivate |
| JP2003531111A (ja) | 1999-12-17 | 2003-10-21 | アライアッド・ファーマシューティカルズ・インコーポレーテッド | プロトンポンプインヒビター |
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| IL150594A0 (en) | 2000-01-07 | 2003-02-12 | Ustav Ex Botan Adademie Ved Ce | Purine derivatives, process for their preparation and use |
| GB2359081A (en) | 2000-02-11 | 2001-08-15 | Astrazeneca Uk Ltd | Pharmaceutically active thiazolopyrimidines |
| MXPA02009543A (es) | 2000-03-29 | 2005-08-26 | Abbott Gmbh & Co Kg | Metodo para identificar inhibidores de tie-2. |
| AU2000240570A1 (en) | 2000-03-29 | 2001-10-08 | Knoll Gesellschaft Mit Beschraenkter Haftung | Pyrrolopyrimidines as tyrosine kinase inhibitors |
| AU2001273040A1 (en) | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
| JP2002105081A (ja) | 2000-07-28 | 2002-04-10 | Nikken Chem Co Ltd | 新規チオフェンニ環化合物 |
| AU2001288735A1 (en) | 2000-09-08 | 2002-03-22 | Glaxo Group Limited | Crystallized cytoplasmic tie2 receptor tyrosine kinase domain and method of determining and designing modulators of the same |
| AU2002217832A1 (en) | 2000-11-15 | 2002-05-27 | Rutgers, The State University Of New Jersey | Black tea extract for prevention of disease |
| JP2004517080A (ja) | 2000-11-29 | 2004-06-10 | グラクソ グループ リミテッド | Tie−2および/またはvegfr−2の阻害剤として有用なベンゾイミダゾール誘導体 |
| MXPA03008560A (es) | 2001-03-22 | 2004-06-30 | Abbot Gmbh & Co Kg | Pirazolopirimidinas como agentes terapeuticos. |
| SE0101322D0 (sv) | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Novel compounds |
| EP1383771A1 (de) | 2001-04-20 | 2004-01-28 | Vertex Pharmaceuticals Incorporated | 9-deazaguaninderivate als gsk-3 inhibitoren |
| WO2003000194A2 (en) | 2001-06-21 | 2003-01-03 | Pfizer Inc. | Thienopyridine and thienopyrimidine anticancer agents |
| WO2003000187A2 (en) | 2001-06-21 | 2003-01-03 | Ariad Pharmaceuticals, Inc. | Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof |
| GB0118479D0 (en) | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
| AU2002333524A1 (en) | 2001-09-11 | 2003-03-24 | Glaxosmithkline K.K. | Furo-and thienopyrimidine derivatives as angiogenesis inhibitors |
| ATE404550T1 (de) | 2001-09-21 | 2008-08-15 | Smithkline Beecham Corp | Chemische verbindungen |
| BR0213562A (pt) | 2001-10-26 | 2004-08-31 | Aventis Pharma Inc | Benzimidazóis e análogos e seu uso como inibidores de cinases de proteìna |
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| ES2314224T3 (es) | 2002-03-07 | 2009-03-16 | F. Hoffmann-La Roche Ag | Inhibidores pirimidina y piridina biciclicos de p38 quinasa. |
-
2003
- 2003-08-01 DE DE60304718T patent/DE60304718T2/de not_active Expired - Fee Related
- 2003-08-01 US US10/523,401 patent/US7427616B2/en not_active Expired - Fee Related
- 2003-08-01 EP EP03766443A patent/EP1537112B1/de not_active Expired - Lifetime
- 2003-08-01 MX MXPA05001389A patent/MXPA05001389A/es unknown
- 2003-08-01 JP JP2004525533A patent/JP2005538118A/ja active Pending
- 2003-08-01 WO PCT/GB2003/003275 patent/WO2004013141A1/en not_active Ceased
- 2003-08-01 CA CA002494421A patent/CA2494421A1/en not_active Abandoned
- 2003-08-01 BR BR0313078-9A patent/BR0313078A/pt not_active Application Discontinuation
- 2003-08-01 AT AT03766443T patent/ATE323702T1/de not_active IP Right Cessation
- 2003-08-01 AU AU2003246972A patent/AU2003246972A1/en not_active Abandoned
- 2003-08-01 KR KR1020057002193A patent/KR20050067383A/ko not_active Withdrawn
- 2003-08-06 AR ARP030102827A patent/AR041189A1/es not_active Application Discontinuation
- 2003-08-06 TW TW092121536A patent/TW200407116A/zh unknown
-
2005
- 2005-01-25 NO NO20050418A patent/NO20050418L/no not_active Application Discontinuation
- 2005-01-26 IL IL16652105A patent/IL166521A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05001389A (es) | 2005-04-28 |
| NO20050418L (no) | 2005-04-28 |
| WO2004013141A1 (en) | 2004-02-12 |
| US7427616B2 (en) | 2008-09-23 |
| KR20050067383A (ko) | 2005-07-01 |
| EP1537112B1 (de) | 2006-04-19 |
| DE60304718D1 (de) | 2006-05-24 |
| CA2494421A1 (en) | 2004-02-12 |
| EP1537112A1 (de) | 2005-06-08 |
| AR041189A1 (es) | 2005-05-04 |
| US20050256140A1 (en) | 2005-11-17 |
| TW200407116A (en) | 2004-05-16 |
| DE60304718T2 (de) | 2007-04-26 |
| BR0313078A (pt) | 2005-07-12 |
| JP2005538118A (ja) | 2005-12-15 |
| IL166521A0 (en) | 2006-01-15 |
| AU2003246972A1 (en) | 2004-02-23 |
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