ATE271545T1 - Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten - Google Patents

Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten

Info

Publication number: ATE271545T1
Authority: AT; Austria
Prior art keywords: fluorophenyl; cyclopropyl; quinolylacrylonitriles; producing; intermediate products
Prior art date: 2000-01-24

Application number

AT01901537T

Other languages

English (en)

Inventor

Katsumasa Harada

Shigeyoshi Nishino

Naoko Okada

Hidetaka Shima

Takashi Harada

Original Assignee

Nissan Chemical Ind Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-24

Filing date

2001-01-24

Publication date

2004-08-15

2001-01-24 Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd

2004-08-15 Application granted granted Critical

2004-08-15 Publication of ATE271545T1 publication Critical patent/ATE271545T1/de

Links

239000013067 intermediate product Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
238000006243 chemical reaction Methods 0.000 abstract 2
JAHBIRPTCXOGLB-UHFFFAOYSA-N 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde Chemical compound C1=CC(F)=CC=C1C1=C(C=O)C(C2CC2)=NC2=CC=CC=C12 JAHBIRPTCXOGLB-UHFFFAOYSA-N 0.000 abstract 1
230000018044 dehydration Effects 0.000 abstract 1
238000006297 dehydration reaction Methods 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Quinoline Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT01901537T 2000-01-24 2001-01-24 Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten ATE271545T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000014864A JP4496586B2 (ja)	2000-01-24	2000-01-24	キノリルアクリロニトリルの製造法及びその中間体
PCT/JP2001/000451 WO2001053264A1 (en)	2000-01-24	2001-01-24	Process for preparing quinolylacrylonitrile and intermediates therefor

Publications (1)

Publication Number	Publication Date
ATE271545T1 true ATE271545T1 (de)	2004-08-15

Family

ID=18542251

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01901537T ATE271545T1 (de)	2000-01-24	2001-01-24	Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten

Country Status (25)

Country	Link
US (1)	US6541636B2 (de)
EP (1)	EP1251123B1 (de)
JP (1)	JP4496586B2 (de)
KR (1)	KR100578776B1 (de)
CN (1)	CN1179946C (de)
AT (1)	ATE271545T1 (de)
AU (1)	AU777959B2 (de)
CA (1)	CA2398113C (de)
CZ (1)	CZ301252B6 (de)
DE (1)	DE60104394T2 (de)
DK (1)	DK1251123T3 (de)
ES (1)	ES2220705T3 (de)
HU (1)	HU230001B1 (de)
IL (2)	IL150881A0 (de)
MX (1)	MXPA02007182A (de)
NO (1)	NO323397B1 (de)
NZ (1)	NZ520415A (de)
PT (1)	PT1251123E (de)
RU (1)	RU2260000C2 (de)
SI (1)	SI1251123T1 (de)
SK (1)	SK286905B6 (de)
TR (1)	TR200401864T4 (de)
UA (1)	UA72025C2 (de)
WO (1)	WO2001053264A1 (de)
ZA (1)	ZA200205849B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7223428B2 (en) *	1998-01-09	2007-05-29	Mars Incorporated	Method of embossing chocolate products
JP2002155056A (ja) *	2000-11-17	2002-05-28	Ube Ind Ltd	キノリルアクリロニトリル誘導体の製法
US20050182125A1 (en) *	2003-05-16	2005-08-18	Ambit Biosciences Corporation	Pyrrole compounds and uses thereof
WO2004110998A1 (en) *	2003-05-16	2004-12-23	Ambit Biosciences Corporation	Pyrrole compounds and uses thereof
US20040248972A1 (en) *	2003-05-16	2004-12-09	Ambit Biosciences Corporation	Compounds and uses thereof
CA2542182A1 (en) *	2003-10-09	2005-04-28	Ecole Polytechnique Federale De Lausanne	Method for identification of suitable fragmentation sites in a reporter protein
BRPI0719449A2 (pt)	2006-12-21	2017-06-20	Syngenta Participations Ag	molécula de ácido nucléico isolada, sintética ou recombinante, polipeptídeo isolado, planta ou parte de planta, eículo de clonagem que compreende um ácido nucléico, cassete de expressão que compreende uma molécula de ácido nucléico e método para hidrolisar um polissacarídeo, oligossacarídeo ou amido
CN102106941B (zh) *	2011-01-30	2012-05-30	广西柳州今传古草生物科技有限公司	治疗痔疮的中药制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2569746B2 (ja) *	1987-08-20	1997-01-08	日産化学工業株式会社	キノリン系メバロノラクトン類
US5008270A (en) *	1989-10-31	1991-04-16	Biocryst, Inc.	2-amino-7-(heterocyclomethyl)-3H,5H-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same
AU654264B2 (en) *	1989-10-31	1994-11-03	Biocryst Pharmaceuticals, Inc.	Inhibitors of purine nucleoside phosphorylase
US5286721A (en) *	1990-10-15	1994-02-15	Fujisawa Pharmaceutical Co., Ltd.	1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
JP3130342B2 (ja) *	1991-10-04	2001-01-31	日産化学工業株式会社	動脈硬化性血管内膜肥厚抑制薬
US5710164A (en) *	1995-06-06	1998-01-20	American Home Products Corporation	Diheterocyclic styryl nitriles
US6335449B1 (en) *	1998-07-23	2002-01-01	Nissan Chemical Industries, Ltd.	Process for the preparation of quinoline derivative and intermediate therefor

2000
- 2000-01-24 JP JP2000014864A patent/JP4496586B2/ja not_active Expired - Fee Related
2001
- 2001-01-24 DE DE60104394T patent/DE60104394T2/de not_active Expired - Lifetime
- 2001-01-24 CZ CZ20022546A patent/CZ301252B6/cs not_active IP Right Cessation
- 2001-01-24 PT PT01901537T patent/PT1251123E/pt unknown
- 2001-01-24 SI SI200130159T patent/SI1251123T1/xx unknown
- 2001-01-24 EP EP01901537A patent/EP1251123B1/de not_active Expired - Lifetime
- 2001-01-24 DK DK01901537T patent/DK1251123T3/da active
- 2001-01-24 TR TR2004/01864T patent/TR200401864T4/xx unknown
- 2001-01-24 WO PCT/JP2001/000451 patent/WO2001053264A1/ja not_active Ceased
- 2001-01-24 RU RU2002122754/04A patent/RU2260000C2/ru not_active IP Right Cessation
- 2001-01-24 US US10/181,973 patent/US6541636B2/en not_active Expired - Lifetime
- 2001-01-24 NZ NZ520415A patent/NZ520415A/en not_active IP Right Cessation
- 2001-01-24 CA CA002398113A patent/CA2398113C/en not_active Expired - Fee Related
- 2001-01-24 ES ES01901537T patent/ES2220705T3/es not_active Expired - Lifetime
- 2001-01-24 AT AT01901537T patent/ATE271545T1/de active
- 2001-01-24 IL IL15088101A patent/IL150881A0/xx unknown
- 2001-01-24 AU AU27099/01A patent/AU777959B2/en not_active Ceased
- 2001-01-24 HU HU0204145A patent/HU230001B1/hu not_active IP Right Cessation
- 2001-01-24 SK SK1081-2002A patent/SK286905B6/sk not_active IP Right Cessation
- 2001-01-24 KR KR1020027009501A patent/KR100578776B1/ko not_active Expired - Fee Related
- 2001-01-24 UA UA2002086974A patent/UA72025C2/uk unknown
- 2001-01-24 CN CNB018070639A patent/CN1179946C/zh not_active Expired - Fee Related
- 2001-01-24 MX MXPA02007182A patent/MXPA02007182A/es active IP Right Grant
2002
- 2002-07-22 ZA ZA200205849A patent/ZA200205849B/en unknown
- 2002-07-23 IL IL150881A patent/IL150881A/en not_active IP Right Cessation
- 2002-07-23 NO NO20023505A patent/NO323397B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA200205849B (en)	2003-10-22
DE60104394D1 (de)	2004-08-26
RU2002122754A (ru)	2004-01-10
SI1251123T1 (en)	2004-10-31
HUP0204145A3 (en)	2005-05-30
HUP0204145A2 (hu)	2003-03-28
KR100578776B1 (ko)	2006-05-12
NO323397B1 (no)	2007-04-23
EP1251123A1 (de)	2002-10-23
ES2220705T3 (es)	2004-12-16
NO20023505D0 (no)	2002-07-23
PT1251123E (pt)	2004-11-30
EP1251123A4 (de)	2003-02-05
RU2260000C2 (ru)	2005-09-10
WO2001053264A1 (en)	2001-07-26
JP2001199962A (ja)	2001-07-24
IL150881A0 (en)	2003-02-12
CZ301252B6 (cs)	2009-12-23
NZ520415A (en)	2003-09-26
CA2398113A1 (en)	2001-07-26
KR20020084099A (ko)	2002-11-04
EP1251123B1 (de)	2004-07-21
SK10812002A3 (sk)	2003-03-04
MXPA02007182A (es)	2003-11-25
JP4496586B2 (ja)	2010-07-07
CN1179946C (zh)	2004-12-15
TR200401864T4 (tr)	2004-08-23
CN1419543A (zh)	2003-05-21
US6541636B2 (en)	2003-04-01
IL150881A (en)	2008-07-08
UA72025C2 (uk)	2005-01-17
DK1251123T3 (da)	2004-11-22
HU230001B1 (en)	2015-04-28
SK286905B6 (sk)	2009-07-06
AU2709901A (en)	2001-07-31
NO20023505L (no)	2002-09-05
AU777959B2 (en)	2004-11-04
US20030013885A1 (en)	2003-01-16
DE60104394T2 (de)	2005-08-18
CA2398113C (en)	2010-01-05

Legal Events

Date

Code

Title

Description

2005-02-15

UEP

Publication of translation of european patent specification

Ref document number: 1251123

Country of ref document: EP

Publication	Publication Date	Title
DE60311599D1 (de)	2007-03-22	Verfahren zur herstellung von duloxetin und deren verwendeten zwischenprodukten
ATE393137T1 (de)	2008-05-15	Verfahren zur herstellung von carbonsäuren und deren derivaten
DE69801764D1 (de)	2001-10-25	Verfahren zur herstellung von citalopram
DE60104394D1 (de)	2004-08-26	Verfahren zur herstellung von quinolylacrylonitrilen and deren zwischenprodukten
ATE356815T1 (de)	2007-04-15	Herstellung von perylen-3,4-dicarbonsäure- anhydriden
ATE444747T1 (de)	2009-10-15	Verfahren zur herstellung von expoxybutanol- zwischenprodukten
MXPA03005429A (es)	2004-05-04	Procedimiento para preparacion de imidazotriazinonas sustituidas con sulfonamida.
ATE276998T1 (de)	2004-10-15	Verfahren zur herstellung von (nitroxymethyl)phenylestern von salicylsäurederivaten
ATE549379T1 (de)	2012-03-15	Verfahren zur herstellung von perylen-3,4:9,10- tetracarbonsäurediimiden und perylen-3,4:9,10- tetracarbonsäuredianhydrid sowie von naphthalin-1,8-dicarbonsäureimiden
DE69808288D1 (de)	2002-10-31	Verfahren zur herstellung von 1,3-dicarbonylverbindungen
ES2169483T3 (es)	2002-07-01	Proceso de preparacion de esteres de acido cinamico.
DE69816080D1 (de)	2003-08-07	Verfahren zur herstellung von chinolinderivaten
ATE269906T1 (de)	2004-07-15	Verbesserungen bezogen auf die herstellung von lactamverbindungen
EP1247807A4 (de)	2003-02-12	Verfahren zur herstellung von tetrahydropyranyl-4-sulfonat und eines 4-aminotetrahydropyranderivates
EA200201233A1 (ru)	2003-04-24	Способ получения бифенильных соединений
EP1067107A4 (de)	2005-05-11	Verfahren zur herstellung von ketoisophoronderivaten and geräte dafür
DE60014103D1 (de)	2004-10-28	Verfahren zur herstellung von debromohymenialdisin und deren analogen
ATE301637T1 (de)	2005-08-15	Verfahren zur herstellung von n-geschützten azetidin-2-carbonsäuren
DE69733716D1 (de)	2005-08-18	Verfahren zur herstellung von imidazolderivaten
ATE288439T1 (de)	2005-02-15	Verfahren zur herstellung von formylphenylboronsäuren
ATE319785T1 (de)	2006-03-15	Verfahren zur herstellung von farbmitteln
DE69024114D1 (de)	1996-01-25	Verfahren zur Herstellung von Penemen
DE69608698D1 (de)	2000-07-06	Verfahren zur herstellung von optisch aktiven carbonsäuren
DE69910978D1 (de)	2003-10-09	Ein verfahren zur herstellung von cyclopropancarbonsäuren
ATE193520T1 (de)	2000-06-15	Verfahren zur herstellung von aminoalkynen