|
GB0404124D0
(en)
|
2004-02-25 |
2004-03-31 |
Univ Ulster |
Antagonists of GIP
|
|
US20050272652A1
(en)
*
|
1999-03-29 |
2005-12-08 |
Gault Victor A |
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
|
|
US6921748B1
(en)
*
|
1999-03-29 |
2005-07-26 |
Uutech Limited |
Analogs of gastric inhibitory polypeptide and their use for treatment of diabetes
|
|
DE19940130A1
(de)
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
|
US6660731B2
(en)
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
WO2002022605A1
(en)
|
2000-09-15 |
2002-03-21 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US20030130199A1
(en)
|
2001-06-27 |
2003-07-10 |
Von Hoersten Stephan |
Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
US6844316B2
(en)
|
2001-09-06 |
2005-01-18 |
Probiodrug Ag |
Inhibitors of dipeptidyl peptidase I
|
|
GB0205693D0
(en)
*
|
2002-03-09 |
2002-04-24 |
Astrazeneca Ab |
Chemical compounds
|
|
US20030232761A1
(en)
*
|
2002-03-28 |
2003-12-18 |
Hinke Simon A. |
Novel analogues of glucose-dependent insulinotropic polypeptide
|
|
WO2003103697A2
(en)
*
|
2002-06-11 |
2003-12-18 |
Cell Therapeutics Scandinavia Ab |
Use of compounds having gip activity for the treatment of disorders associated with abnormal loss of cells and/or for the treatment of obesity
|
|
BR0311843A
(pt)
*
|
2002-06-15 |
2005-03-15 |
Enteromed Inc |
Métodos para prevenir, inibir, tratar ou reduzir esteatose hepática não- alcoólica em um animal e para prevenir o desenvolvimento e/ou a reversão do processo de nafld em um animal
|
|
US7601718B2
(en)
|
2003-02-06 |
2009-10-13 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of protein kinases
|
|
WO2004098591A2
(en)
|
2003-05-05 |
2004-11-18 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
|
|
EP1961416B1
(de)
|
2003-05-05 |
2013-01-23 |
Probiodrug AG |
Verwendung von Hemmern von Glutaminylcyclase zur Behandlung von Rheumatoider Arthritis, Psoriasis oder Atherosklerose
|
|
BRPI0415409A
(pt)
|
2003-10-15 |
2006-12-05 |
Probiodrug Ag |
uso de efetuadores de ciclases de glutaminila e glutamato
|
|
US7595294B2
(en)
*
|
2004-10-08 |
2009-09-29 |
Transition Therapeutics, Inc. |
Vasoactive intestinal polypeptide pharmaceuticals
|
|
AU2005298689A1
(en)
|
2004-10-25 |
2006-05-04 |
Cytos Biotechnology Ag |
Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof
|
|
AU2006204334B2
(en)
|
2005-01-10 |
2012-02-23 |
Cortendo Ab (Publ) |
Methods and compositions for treating diabetes, metabolic syndrome and other conditions
|
|
KR20070115947A
(ko)
|
2005-02-11 |
2007-12-06 |
아밀린 파마슈티칼스, 인크. |
선택가능한 특성들을 가지는 gip 유사체 및 하이브리드폴리펩타이드
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
CA2623412A1
(en)
*
|
2005-09-08 |
2007-03-15 |
Uutech Limited |
Analogs of gastric inhibitory polypeptide as a treatment for age related decreased pancreatic beta cell function
|
|
CA2622069A1
(en)
*
|
2005-09-08 |
2007-03-15 |
Uutech Limited |
Treatment of diabetes related obesity
|
|
MX2008005814A
(es)
|
2005-11-03 |
2008-10-15 |
Vertex Pharma |
Aminopirimidinas utiles como inhibidores de cinasa.
|
|
CA2913805A1
(en)
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
AU2007303219A1
(en)
|
2006-10-02 |
2008-04-10 |
Cortendo Ab (Publ) |
Ketoconazole enantiomer in humans
|
|
CA2668429A1
(en)
|
2006-11-02 |
2008-05-15 |
Vertex Pharmaceuticals Incorporated |
Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
|
|
EP1935420A1
(de)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-Butyramid Derivate als selektive 11Beta-HSD1 Inhibitoren
|
|
RU2477286C2
(ru)
|
2007-01-05 |
2013-03-10 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
АНАЛОГИ ГЛЮКАГОНА, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ РАСТВОРИМОСТЬЮ В БУФЕРАХ С ФИЗИОЛОГИЧЕСКИМ ЗНАЧЕНИЕМ pH
|
|
CA2677932A1
(en)
|
2007-02-15 |
2008-08-21 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
|
EP2134709A1
(de)
|
2007-03-09 |
2009-12-23 |
Vertex Pharmaceuticals, Inc. |
Aminopyridine als proteinkinasehemmer
|
|
EP2137183B1
(de)
*
|
2007-03-09 |
2011-09-28 |
Vertex Pharmaceuticals Incorporated |
Als inhibitoren von proteinkinasen geeignete aminopyrimidine
|
|
NZ580343A
(en)
|
2007-04-13 |
2012-03-30 |
Vertex Pharma |
Aminopyrimidines useful as kinase inhibitors
|
|
JP5389785B2
(ja)
|
2007-05-02 |
2014-01-15 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼ阻害剤として有用なチアゾールおよびピラゾール
|
|
NZ582879A
(en)
|
2007-07-31 |
2012-03-30 |
Vertex Pharma |
Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
|
|
MX2010004298A
(es)
|
2007-10-30 |
2010-05-03 |
Univ Indiana Res & Tech Corp |
Compuestos que exhiben actividad antagonista de glucagon y agonista de glp-1.
|
|
ES2509883T3
(es)
|
2007-10-30 |
2014-10-20 |
Indiana University Research And Technology Corporation |
Antagonistas de glucagón
|
|
EP2249853A4
(de)
|
2008-01-30 |
2012-12-26 |
Univ Indiana Res & Tech Corp |
Peptid-prodrugs auf esterbasis
|
|
EP2110374A1
(de)
|
2008-04-18 |
2009-10-21 |
Merck Sante |
Benzofuran, Benzothiophen, Benzothiazolderivate als FXR-Modulatoren
|
|
AR072160A1
(es)
|
2008-06-17 |
2010-08-11 |
Univ Indiana Res & Tech Corp |
Co-agonistas del receptor de glucagon/glp-1
|
|
CN102105159B
(zh)
|
2008-06-17 |
2015-07-08 |
印第安纳大学研究及科技有限公司 |
基于gip的混合激动剂用于治疗代谢紊乱和肥胖症
|
|
US8450270B2
(en)
|
2008-06-17 |
2013-05-28 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers
|
|
US9187426B2
(en)
|
2008-06-27 |
2015-11-17 |
Novartis Ag |
Organic compounds
|
|
WO2010016940A2
(en)
*
|
2008-08-07 |
2010-02-11 |
Ipsen Pharma S.A.S. |
Analogues of glucose-dependent insulinotropic polypeptide
|
|
WO2010016936A1
(en)
*
|
2008-08-07 |
2010-02-11 |
Ipsen Pharma S.A.S. |
Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide
|
|
KR20110043687A
(ko)
|
2008-08-07 |
2011-04-27 |
입센 파마 에스.에이.에스 |
포도당 의존적인 인슐린 분비 자극성 폴리펩타이드의 절단형 유사체
|
|
ES2574835T3
(es)
*
|
2008-08-07 |
2016-06-22 |
Ipsen Pharma S.A.S. |
Análogos del polipéptido insulinotrópico dependiente de glucosa
|
|
AU2009280021B2
(en)
*
|
2008-08-07 |
2012-10-04 |
Ipsen Pharma S.A.S. |
Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
|
|
EP2358200A4
(de)
|
2008-11-17 |
2012-05-16 |
Merck Sharp & Dohme |
Substituierte bizyklische amine für die behandlung von diabetes
|
|
PE20120332A1
(es)
*
|
2008-12-19 |
2012-04-14 |
Univ Indiana Res & Tech Corp |
Profarmacos de peptido de la superfamilia de glucagon basado en amida
|
|
WO2010080605A1
(en)
*
|
2008-12-19 |
2010-07-15 |
Indiana University Research And Technology Corporation |
Dipeptide linked medicinal agents
|
|
JP5789515B2
(ja)
|
2008-12-19 |
2015-10-07 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
インスリン類似体
|
|
AU2009335715B2
(en)
|
2008-12-19 |
2016-09-15 |
Indiana University Research And Technology Corporation |
Amide-based insulin prodrugs
|
|
CN102388052A
(zh)
|
2009-04-01 |
2012-03-21 |
诺瓦提斯公司 |
调节硬脂酰基-CoA去饱和酶的螺环衍生物
|
|
EP2443146B1
(de)
|
2009-06-16 |
2016-10-05 |
Indiana University Research And Technology Corporation |
Gip-rezeptor-aktive glucagon-verbindungen
|
|
CA2768577A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
|
WO2011014680A2
(en)
*
|
2009-07-31 |
2011-02-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Gastric inhibitory peptide variants and their uses
|
|
BR112012007509A2
(pt)
|
2009-10-01 |
2016-11-22 |
Novartis Ag |
derivados pirazóis que modulam estearoil-coa dessaturase
|
|
WO2011058193A1
(en)
|
2009-11-16 |
2011-05-19 |
Mellitech |
[1,5]-diazocin derivatives
|
|
US8703701B2
(en)
|
2009-12-18 |
2014-04-22 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
|
CN102791701B
(zh)
|
2009-12-30 |
2014-02-12 |
深圳信立泰药业股份有限公司 |
作为二肽基肽酶iv(dpp-iv)抑制剂的3-(3-氨基哌啶-1-基)-5-氧代-1,2,4-三嗪衍生物
|
|
KR20120123443A
(ko)
|
2010-01-27 |
2012-11-08 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
대사 장애 및 비만 치료용 글루카곤 길항제-gip 항진제 콘쥬게이트
|
|
MX2012013001A
(es)
|
2010-05-13 |
2013-02-26 |
Univ Indiana Res & Tech Corp |
Peptidos de la superfamilia de glucagon que presentan actividad del receptor nuclear de hormonas.
|
|
JP6050746B2
(ja)
|
2010-05-13 |
2016-12-21 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
Gタンパク質共役受容体活性を示すグルカゴンスーパーファミリーのペプチド
|
|
JP5969469B2
(ja)
|
2010-06-16 |
2016-08-17 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
インスリン受容体に対して高い活性を示す単鎖インスリンアゴニスト
|
|
EP2588126A4
(de)
|
2010-06-24 |
2015-07-08 |
Univ Indiana Res & Tech Corp |
Amidbasierte glucagon-superfamilien-peptid-prodrugs
|
|
EP2585102B1
(de)
|
2010-06-24 |
2015-05-06 |
Indiana University Research and Technology Corporation |
Auf amid basierende insulin-prodrugs
|
|
US9023986B2
(en)
|
2010-10-25 |
2015-05-05 |
Hoffmann-La Roche Inc. |
Glucose-dependent insulinotropic peptide analogs
|
|
US8507428B2
(en)
|
2010-12-22 |
2013-08-13 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting GIP receptor activity
|
|
US20140377171A1
(en)
*
|
2011-06-10 |
2014-12-25 |
Jean Claude Reubi |
Imaging and Treatment of Neuroendocrine Tumors with Glucose - Dependent Insulinotropic Polypeptide or Analogues or Antagonists Thereof
|
|
KR20140043793A
(ko)
|
2011-06-22 |
2014-04-10 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
글루카곤/glp-1 수용체 공동-작용물질
|
|
RS56173B1
(sr)
|
2011-06-22 |
2017-11-30 |
Univ Indiana Res & Tech Corp |
Koagonisti receptora za glukagon/glp-1 receptora
|
|
JP6324315B2
(ja)
|
2011-11-17 |
2018-05-16 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
グルココルチコイド受容体の活性を示すグルカゴンスーパーファミリーのペプチド
|
|
BR112014015156A2
(pt)
|
2011-12-20 |
2020-10-27 |
Indiana University Research And Technology Corporation |
análogos de insulina à base de ctp, seus métodos de produção e uso no tratamento de hiperglicemia, bem como sequência de ácido nucleico e célula hospedeira
|
|
JP2015519309A
(ja)
|
2012-04-16 |
2015-07-09 |
カネック ファーマ インコーポレイテッド |
Ptp−1bインヒビター前駆体としての縮合芳香族ホスホナート誘導体
|
|
CN104583232B
(zh)
|
2012-06-21 |
2018-04-13 |
印第安纳大学研究及科技有限公司 |
展现gip受体活性的胰高血糖素类似物
|
|
FR2994848B1
(fr)
|
2012-08-30 |
2014-08-22 |
Univ Paris Curie |
Traitement de l'arthrose par les hormones incretines ou leurs analogues
|
|
EP3395358B1
(de)
|
2012-09-26 |
2019-11-06 |
Indiana University Research and Technology Corporation |
Insulinanalogdimere
|
|
JP6538645B2
(ja)
|
2013-03-14 |
2019-07-03 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
インスリン‐インクレチン複合物
|
|
ES2685987T3
(es)
|
2014-09-05 |
2018-10-15 |
University Of Copenhagen |
Análogos de péptidos gip
|
|
CN108271356A
(zh)
|
2014-09-24 |
2018-07-10 |
印第安纳大学研究及科技有限公司 |
肠降血糖素-胰岛素缀合物
|
|
JP6701208B2
(ja)
|
2014-09-24 |
2020-05-27 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
脂質化アミド系インスリンプロドラッグ
|
|
KR102620911B1
(ko)
|
2014-10-29 |
2024-01-05 |
질랜드 파마 에이/에스 |
Gip 효능제 화합물 및 방법
|
|
UA127495C2
(uk)
|
2015-12-23 |
2023-09-13 |
Амджен Інк. |
Виділений антигензв'язуючий білок, який специфічно зв'язується з поліпептидом рецептора шлункового інгібіторного пептиду (gipr) людини, та фармацевтична композиція, яка його містить
|
|
IL313587A
(en)
|
2017-01-17 |
2024-08-01 |
Amgen Inc |
Method of treating or ameliorating metabolic disorders using glp-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (gipr)
|
|
KR102743887B1
(ko)
|
2017-05-31 |
2024-12-19 |
유니버시티 오브 코펜하겐 |
장기-작용성 gip 펩타이드 유사체
|
|
EA201992502A1
(ru)
|
2017-06-20 |
2020-04-22 |
Эмджен Инк. |
Способ лечения или уменьшения интенсивности метаболических нарушений с применением белков, связывающих рецептор гастроингибиторного пептида (gipr), в комбинации с агонистами glp-1
|
|
EP3642238A1
(de)
|
2017-06-21 |
2020-04-29 |
Amgen Inc. |
Verfahren zur behandlung oder linderung von stoffwechselstörungen unter verwendung von antagonistischen bindungsproteinen für rezeptoragonistfusionsproteine des gastrischen inhibitorpeptidrezeptors (gipr)/glp-1
|
|
US11633459B2
(en)
*
|
2018-05-04 |
2023-04-25 |
Novo Nordisk A/S |
GIP derivatives and uses thereof
|
|
WO2020074958A1
(en)
|
2018-10-12 |
2020-04-16 |
Strongbridge Dublin Limited |
Levoketoconazole for treatment of congenital adrenal hyperplasia and primary aldosteronism
|
|
SG11202105586YA
(en)
|
2018-12-03 |
2021-06-29 |
Antag Therapeutics Aps |
Modified gip peptide analogues
|
|
WO2024123812A1
(en)
*
|
2022-12-05 |
2024-06-13 |
Shattuck Labs, Inc. |
Fusion proteins for the treatment of cardiometabolic diseases
|