ATE274504T1 - Verfahren zur herstellung von einem kristallepoxid - Google Patents
Verfahren zur herstellung von einem kristallepoxidInfo
- Publication number
- ATE274504T1 ATE274504T1 AT01310368T AT01310368T ATE274504T1 AT E274504 T1 ATE274504 T1 AT E274504T1 AT 01310368 T AT01310368 T AT 01310368T AT 01310368 T AT01310368 T AT 01310368T AT E274504 T1 ATE274504 T1 AT E274504T1
- Authority
- AT
- Austria
- Prior art keywords
- epoxide compound
- epoxy
- producing
- phenylbutane
- butoxycarbonylamino
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000004593 Epoxy Substances 0.000 title 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- NVPOUMXZERMIJK-STQMWFEESA-N tert-butyl n-[(1s)-1-[(2r)-oxiran-2-yl]-2-phenylethyl]carbamate Chemical compound C([C@H](NC(=O)OC(C)(C)C)[C@H]1OC1)C1=CC=CC=C1 NVPOUMXZERMIJK-STQMWFEESA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/36—Use of additives, e.g. for stabilisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000377804 | 2000-12-12 | ||
| JP2001051108 | 2001-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274504T1 true ATE274504T1 (de) | 2004-09-15 |
Family
ID=26605686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01310368T ATE274504T1 (de) | 2000-12-12 | 2001-12-12 | Verfahren zur herstellung von einem kristallepoxid |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6764545B2 (de) |
| EP (1) | EP1215209B1 (de) |
| KR (1) | KR20020046948A (de) |
| AT (1) | ATE274504T1 (de) |
| CA (1) | CA2364838A1 (de) |
| DE (1) | DE60105113T2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS51073B (sr) | 2003-12-23 | 2010-10-31 | Tibotec Pharmaceuticals Ltd. | Proces za pripremanje (3r,3as,6ar)-heksahidrofuro│2,3-b│ furan-3-il (1s,2r)-3-││(4-aminofenil) sulfonil│(izobutil) amino │-1-benzil-2-hidroksipropilkarbamata |
| DE602004021640D1 (de) | 2003-12-23 | 2009-07-30 | Tibotec Pharm Ltd | Verfahren zur herstellung von (1s,2r)-3-ää(4-aminophenyl)sulfonylü(isobutyl)aminoü-1-benzyl-2-hydroxypropylcarbamidsäure-(3r,3as,6ar)-hexahydrofuroä2,3-büfuran-3-ylester |
| WO2006126255A1 (ja) | 2005-05-24 | 2006-11-30 | Daito Chemix Corporation | Ｎ－（２－ブロモエチル）カルバミン酸ｔｅｒｔ－ブチルの製造方法 |
| US7582468B2 (en) * | 2005-05-25 | 2009-09-01 | Bristol-Myers Squibb Company | Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof |
| JP2007112723A (ja) * | 2005-10-18 | 2007-05-10 | Ajinomoto Co Inc | アミノクロロヒドリン硫酸塩の製造方法 |
| ES2359949T3 (es) | 2006-11-09 | 2011-05-30 | Tibotec Pharmaceuticals | Métodos para preparar hexhidrofuro(2,3-b)furan-3-ol. |
| BRPI0810609A2 (pt) | 2007-04-27 | 2014-10-21 | Tibotec Pharm Ltd | Métodos para a preparação de derivados de n-isobutil-n-(2-hidróxi-a-amino-4-fenilbutil)-p-nitrobe nzenossulfonilamida |
| SI2170292T1 (sl) * | 2007-06-22 | 2014-05-30 | Bristol-Myers Squibb Holdings Ireland | Tabletirani sestavki, ki vsebujejo atazanavir |
| JP2010530892A (ja) * | 2007-06-22 | 2010-09-16 | ブリストル−マイヤーズ スクイブ カンパニー | アタザナビルを含む錠剤組成物 |
| JP2010530889A (ja) * | 2007-06-22 | 2010-09-16 | ブリストル−マイヤーズ スクイブ カンパニー | アタザナビルを含む錠剤組成物 |
| ES2359770T3 (es) * | 2007-06-22 | 2011-05-26 | Bristol-Myers Squibb Company | Composiciones en comprimidos que contienen atazanavir. |
| WO2009136365A1 (en) * | 2008-05-08 | 2009-11-12 | Ranbaxy Laboratories Limited | Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof |
| KR100970596B1 (ko) * | 2008-06-24 | 2010-07-16 | 대한주택공사 | 선상이동이 가능한 도어벽체 구조 |
| AR073248A1 (es) | 2008-09-01 | 2010-10-20 | Tibotec Pharm Ltd | Proceso para la preparacion de (1s, 2r)-3- ((4-aminofenil) sulfonil) ( isobutil) amino)-1- bencil-2- hidroxipropilcarbamato de (3r, 3as,6ar)- hexahidrofuro-(2,3-b) furan-3- ilo (darunavir) y compuestos intermediarios utiles en dicho proceso. |
| US8921415B2 (en) | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
| EP2528923B1 (de) | 2010-01-28 | 2014-07-30 | Mapi Pharma Limited | Verfahren zur herstellung von darunavir und darunavir-zwischenprodukten |
| CN103044361B (zh) * | 2012-12-30 | 2014-08-06 | 江苏八巨药业有限公司 | 一种（2r,3s）-环氧化氨基苯丁烷的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH515925A (de) * | 1968-11-21 | 1971-11-30 | Ciba Geigy Ag | Verfahren zur Herstellung neuer B-Methylglycidyl-isocyanurate und ihre Verwendung zur Herstellung härtbarer Massen |
| US3676433A (en) * | 1970-09-15 | 1972-07-11 | Upjohn Co | Improved process for the 5{60 ,6{60 -epoxidation of {66 {11 -double bonds |
| US5166371A (en) * | 1989-07-31 | 1992-11-24 | Arco Chemical Technology, L.P. | Asymmetric epoxidation using a chiral hydroperoxide |
| US5559256A (en) | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
| US5481011A (en) | 1994-12-13 | 1996-01-02 | Bristol-Myers Squibb Company | Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters |
| KR100411856B1 (ko) * | 1995-02-03 | 2004-05-20 | 카네카 코포레이션 | α-할로케톤,α-할로히드린및에폭사이드의제조법 |
| JP4250335B2 (ja) | 1998-01-28 | 2009-04-08 | 日本化薬株式会社 | 光学活性スレオ−３−アミノ−１，２−エポキシ体の製造法 |
| EP1067125B1 (de) | 1999-01-29 | 2006-07-26 | Kaneka Corporation | VERFAHREN ZUR HERSTELLUNG VON threo-1,2-EPOXY-3-AMINO-4-PHENYLBUTAN-DERIVATEN |
| KR100708221B1 (ko) | 1999-08-31 | 2007-04-17 | 아지노모토 가부시키가이샤 | 에폭사이드 결정의 제조방법 |
-
2001
- 2001-12-11 KR KR1020010078050A patent/KR20020046948A/ko not_active Abandoned
- 2001-12-11 US US10/011,304 patent/US6764545B2/en not_active Expired - Fee Related
- 2001-12-12 EP EP01310368A patent/EP1215209B1/de not_active Expired - Lifetime
- 2001-12-12 CA CA002364838A patent/CA2364838A1/en not_active Abandoned
- 2001-12-12 AT AT01310368T patent/ATE274504T1/de not_active IP Right Cessation
- 2001-12-12 DE DE60105113T patent/DE60105113T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1215209A1 (de) | 2002-06-19 |
| EP1215209B1 (de) | 2004-08-25 |
| US6764545B2 (en) | 2004-07-20 |
| US20020087014A1 (en) | 2002-07-04 |
| DE60105113D1 (de) | 2004-09-30 |
| DE60105113T2 (de) | 2005-08-18 |
| KR20020046948A (ko) | 2002-06-21 |
| CA2364838A1 (en) | 2002-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60105113D1 (de) | Verfahren zur Herstellung von einem Kristallepoxid | |
| ATE506356T1 (de) | Verfahren zur herstellung von 3-halo-4,5-dihydro- 1h-pyrazolen | |
| ATE329891T1 (de) | Kristallisierung von materialien aus wässerigen lösungen | |
| EP1277752A4 (de) | Verfahren zur herstellung von optisch-aktiven sulfoxid-derivaten | |
| ATE170513T1 (de) | Diastereomeres salz von optisch aktiver chinolinmevalonsäure | |
| IS2737B (is) | Fyrirkomulag til þess að rétta af fisk | |
| DK0617018T3 (da) | Beta-Lactamer, fremgangsmåde til fremstilling af taxaner og sidekæde-bærende taxaner | |
| DE602004004095D1 (de) | Tiegel für eine vorrichtung zur herstellung eines kristallinen blockes, und verfahren zu seiner herstellung | |
| ATE157647T1 (de) | Verfahren zur herstellung von alpha- ketoamidderivaten | |
| DE69513657D1 (de) | Verfahren zur Herstellung von 1-substituierten 2-Cyanoimidazolen | |
| ATE375338T1 (de) | Verfahren zur aufreinigung von lanzoprazol | |
| BR9913720A (pt) | Processo de purificação por cristalização ourecristalização de ácidos carboxìlicos | |
| ATE461170T1 (de) | Verfahren zur herstellung von bicalutamid und verfahren zur aufreinigung von zwischenprodukten dafür | |
| ATE496907T1 (de) | Verfahren zur herstellung von cilostazol | |
| DK0782996T3 (da) | Fremgangsmåde til fremstilling af N-biphenylmethylthiadiazolinderivat eller salt deraf og mellemprodukt til fremstilling af | |
| DE60116796D1 (de) | Prozess zur herstellung von r(+)alpha-liponsäure | |
| ATE321033T1 (de) | Verfahren zur herstellung von substituierten alkylaminen oder salzen davon | |
| ATE157971T1 (de) | Verfahren zur herstellung von aminotriazin- derivaten | |
| ATE390400T1 (de) | Verfahren zur herstellung von alpha'-chlorketonen | |
| DE60040592D1 (de) | Verfahren zur herstellung von alpha-aminoketonen | |
| DE60039533D1 (de) | Verbessertes verfahren zur herstellung von 2s,3s-n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamid hydrochlorid und anderen derivaten von 2-hydroxy-1,3-diamin | |
| ATE360006T1 (de) | Verfahren zur racematspaltung von nefopam | |
| DE60019723D1 (de) | Eine methode zur herstellung von verbindungen der formel 1 und derivaten | |
| ATE318264T1 (de) | Laktonisierungsverfahren bei der herstellung von statinen | |
| EP1489066A4 (de) | Verfahren zur herstellung von optisch aktiver carbonsäure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |