ATE274504T1 - Verfahren zur herstellung von einem kristallepoxid - Google Patents
Verfahren zur herstellung von einem kristallepoxidInfo
- Publication number
- ATE274504T1 ATE274504T1 AT01310368T AT01310368T ATE274504T1 AT E274504 T1 ATE274504 T1 AT E274504T1 AT 01310368 T AT01310368 T AT 01310368T AT 01310368 T AT01310368 T AT 01310368T AT E274504 T1 ATE274504 T1 AT E274504T1
- Authority
- AT
- Austria
- Prior art keywords
- epoxide compound
- epoxy
- producing
- phenylbutane
- butoxycarbonylamino
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000004593 Epoxy Substances 0.000 title 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- NVPOUMXZERMIJK-STQMWFEESA-N tert-butyl n-[(1s)-1-[(2r)-oxiran-2-yl]-2-phenylethyl]carbamate Chemical compound C([C@H](NC(=O)OC(C)(C)C)[C@H]1OC1)C1=CC=CC=C1 NVPOUMXZERMIJK-STQMWFEESA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/36—Use of additives, e.g. for stabilisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000377804 | 2000-12-12 | ||
| JP2001051108 | 2001-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274504T1 true ATE274504T1 (de) | 2004-09-15 |
Family
ID=26605686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01310368T ATE274504T1 (de) | 2000-12-12 | 2001-12-12 | Verfahren zur herstellung von einem kristallepoxid |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6764545B2 (de) |
| EP (1) | EP1215209B1 (de) |
| KR (1) | KR20020046948A (de) |
| AT (1) | ATE274504T1 (de) |
| CA (1) | CA2364838A1 (de) |
| DE (1) | DE60105113T2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4818124B2 (ja) | 2003-12-23 | 2011-11-16 | テイボテク・フアーマシユーチカルズ・リミテツド | （３Ｒ，３ａＳ，６ａＲ）−ヘキサヒドロフロ〔２，３−ｂ〕フラン−３−イル（１Ｓ，１Ｒ）−３−〔〔（４−アミノフェニル）スルホニル〕（イソブチル）アミノ〕−１−ベンジル−２−ヒドロキシプロピルカルバマートの製造方法 |
| PT1725566E (pt) | 2003-12-23 | 2009-09-16 | Tibotec Pharm Ltd | Processo para a preparação de (1s,2r)-3-[[(4-aminofenil) sulfonil](isobutil)amino]-1-benzil-2-hidroxipropilcarbamato de (3r,3as,6ar)-hexa-hidrofuro[2,3-b]furan-3-ilo |
| WO2006126255A1 (ja) | 2005-05-24 | 2006-11-30 | Daito Chemix Corporation | Ｎ－（２－ブロモエチル）カルバミン酸ｔｅｒｔ－ブチルの製造方法 |
| US7582468B2 (en) * | 2005-05-25 | 2009-09-01 | Bristol-Myers Squibb Company | Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof |
| JP2007112723A (ja) * | 2005-10-18 | 2007-05-10 | Ajinomoto Co Inc | アミノクロロヒドリン硫酸塩の製造方法 |
| CN102432621B (zh) | 2006-11-09 | 2016-02-17 | 爱尔兰詹森科学公司 | 六氢呋喃并[2,3-b]呋喃-3-醇的制备方法 |
| WO2008132154A1 (en) | 2007-04-27 | 2008-11-06 | Tibotec Pharmaceuticals Ltd. | Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives |
| MX2009013499A (es) * | 2007-06-22 | 2010-01-18 | Bristol Myers Squibb Co | Composiciones comprimidas que contienen atazanavir. |
| CN101778624A (zh) * | 2007-06-22 | 2010-07-14 | 百时美施贵宝公司 | 含有阿扎那韦的压片组合物 |
| DE602008005316D1 (de) * | 2007-06-22 | 2011-04-14 | Bristol Myers Squibb Co | Tablettierte atazanavirhaltige zusammensetzungen |
| JP2010530892A (ja) * | 2007-06-22 | 2010-09-16 | ブリストル−マイヤーズ スクイブ カンパニー | アタザナビルを含む錠剤組成物 |
| US20110178305A1 (en) * | 2008-05-08 | 2011-07-21 | Ranbaxy Laboratories Limited | Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof |
| KR100970596B1 (ko) * | 2008-06-24 | 2010-07-16 | 대한주택공사 | 선상이동이 가능한 도어벽체 구조 |
| TWI482775B (zh) | 2008-09-01 | 2015-05-01 | Tibotec Pharm Ltd | 用於製備（３ｒ，３ａｓ，６ａｒ）－六氫呋喃并〔２，３－ｂ〕呋喃－３－基（１ｓ，２ｒ）－３－〔〔（４－胺基苯基）磺醯基〕（異丁基）胺基〕－１－苯甲基－２－羥基丙基胺基甲酸酯之方法 |
| US8921415B2 (en) | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
| EP2528923B1 (de) | 2010-01-28 | 2014-07-30 | Mapi Pharma Limited | Verfahren zur herstellung von darunavir und darunavir-zwischenprodukten |
| CN103044361B (zh) * | 2012-12-30 | 2014-08-06 | 江苏八巨药业有限公司 | 一种（2r,3s）-环氧化氨基苯丁烷的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH515925A (de) * | 1968-11-21 | 1971-11-30 | Ciba Geigy Ag | Verfahren zur Herstellung neuer B-Methylglycidyl-isocyanurate und ihre Verwendung zur Herstellung härtbarer Massen |
| US3676433A (en) * | 1970-09-15 | 1972-07-11 | Upjohn Co | Improved process for the 5{60 ,6{60 -epoxidation of {66 {11 -double bonds |
| US5166371A (en) * | 1989-07-31 | 1992-11-24 | Arco Chemical Technology, L.P. | Asymmetric epoxidation using a chiral hydroperoxide |
| US5559256A (en) | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
| US5481011A (en) | 1994-12-13 | 1996-01-02 | Bristol-Myers Squibb Company | Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters |
| DE69616446T2 (de) | 1995-02-03 | 2002-05-16 | Kaneka Corp., Osaka | Verfahren zur herstellung von alpha-haloketonen, alpha-halohydrinen und epoxiden |
| US6376685B1 (en) | 1998-01-28 | 2002-04-23 | Nippon Kayaku Kabushiki Kaisha | Process for producing optically active threo-3-amino-1,2-epoxy compounds |
| AU2322600A (en) | 1999-01-29 | 2000-08-18 | Kaneka Corporation | Processes for the preparation of (threo)-1,2-epoxy-3-amino-4-phenylbutane derivatives |
| KR100708221B1 (ko) | 1999-08-31 | 2007-04-17 | 아지노모토 가부시키가이샤 | 에폭사이드 결정의 제조방법 |
-
2001
- 2001-12-11 US US10/011,304 patent/US6764545B2/en not_active Expired - Fee Related
- 2001-12-11 KR KR1020010078050A patent/KR20020046948A/ko not_active Abandoned
- 2001-12-12 EP EP01310368A patent/EP1215209B1/de not_active Expired - Lifetime
- 2001-12-12 DE DE60105113T patent/DE60105113T2/de not_active Expired - Fee Related
- 2001-12-12 CA CA002364838A patent/CA2364838A1/en not_active Abandoned
- 2001-12-12 AT AT01310368T patent/ATE274504T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2364838A1 (en) | 2002-06-12 |
| KR20020046948A (ko) | 2002-06-21 |
| EP1215209B1 (de) | 2004-08-25 |
| US6764545B2 (en) | 2004-07-20 |
| US20020087014A1 (en) | 2002-07-04 |
| DE60105113D1 (de) | 2004-09-30 |
| DE60105113T2 (de) | 2005-08-18 |
| EP1215209A1 (de) | 2002-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |