ATE275153T1 - Antibiotika produzierende mikrobe - Google Patents

Antibiotika produzierende mikrobe

Info

Publication number: ATE275153T1
Authority: AT; Austria
Prior art keywords: producing microbe; antibiotic producing; microbe; cyclosporin; antibiotic
Prior art date: 1996-06-05

Application number

AT97923272T

Other languages

English (en)

Inventor

Enrico Casareto

Massimo Leoni

Enrico Ronzio

Ambrogio Magni

Original Assignee

Poli Ind Chimica Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-05

Filing date

1997-06-05

Publication date

2004-09-15

1997-06-05 Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa

2004-09-15 Application granted granted Critical

2004-09-15 Publication of ATE275153T1 publication Critical patent/ATE275153T1/de

Links

230000003115 biocidal effect Effects 0.000 title 1
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 3
229930105110 Cyclosporin A Natural products 0.000 abstract 3
108010036949 Cyclosporine Proteins 0.000 abstract 3
229960001265 ciclosporin Drugs 0.000 abstract 3
229930182912 cyclosporin Natural products 0.000 abstract 3
238000012258 culturing Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Compounds Of Unknown Constitution (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT97923272T 1996-06-05 1997-06-05 Antibiotika produzierende mikrobe ATE275153T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/658,653 US5747330A (en)	1996-06-05	1996-06-05	Antibiotic producing microbe
PCT/IB1997/000654 WO1997046580A1 (en)	1996-06-05	1997-06-05	Antibiotic producing microbe

Publications (1)

Publication Number	Publication Date
ATE275153T1 true ATE275153T1 (de)	2004-09-15

Family

ID=24642117

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97923272T ATE275153T1 (de)	1996-06-05	1997-06-05	Antibiotika produzierende mikrobe

Country Status (8)

Country	Link
US (2)	US5747330A (de)
EP (1)	EP0906336B1 (de)
AT (1)	ATE275153T1 (de)
AU (1)	AU2912297A (de)
CA (1)	CA2257254C (de)
DE (1)	DE69730497D1 (de)
ES (1)	ES2227693T3 (de)
WO (2)	WO1997046575A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6176701B1 (en) *	1997-10-01	2001-01-23	Barnett Joel Robinson	Method for improving fuel efficiency in combustion chambers
US20030220234A1 (en) *	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
EP0991660B8 (de)	1997-10-08	2006-04-05	Isotechnika,Inc.	DEUTERIERtE und undeuterierte CYCLOSPORIN-ANALOGA UND IHRE VERWENDUNG ALS IMMUNMODULIERENDE AGENtIEN
EP1154759B1 (de)	1998-12-30	2008-08-13	Dexcel Ltd.	Dispergierbares konzentrat zur verabreichung von cyclosporin
US7732404B2 (en) *	1999-12-30	2010-06-08	Dexcel Ltd	Pro-nanodispersion for the delivery of cyclosporin
AU2000235743A1 (en)	2000-02-29	2001-09-12	Biocon India Limited	Manufacture and purification of cyclosporin a
US6547900B2 (en)	2001-01-24	2003-04-15	Breed Automotive Technology, Inc.	Method of stabilizing the density of gas generant pellets containing nitroguanidine
US7141648B2 (en)	2001-10-19	2006-11-28	Isotechnika Inc.	Synthesis of cyclosporin analogs
EP1603512A2 (de)	2003-03-17	2005-12-14	Albany Molecular Research, Inc.	Neue cyclosporine
US7378391B2 (en)	2004-09-29	2008-05-27	Amr Technology, Inc.	Cyclosporin alkyne analogues and their pharmaceutical uses
WO2006041631A2 (en)	2004-10-06	2006-04-20	Amr Technology, Inc.	Novel cyclosporin alkynes and their utility as pharmaceutical agents
KR101072121B1 (ko)	2008-02-19	2011-10-10	(주)차바이오앤디오스텍	톨리포클라디움 니베움에서 사이클로스포린 대량 생산 방법
EP2151450A1 (de)	2008-07-29	2010-02-10	Sandoz AG	Verfahren zur Aufarbeitung von mikrobiologisch hergestellten zyklischen Oligopeptiden
US10945443B2 (en)	2017-09-29	2021-03-16	Valent Biosciences Llc	Tolypocladium album strain
CN115125148A (zh) *	2021-03-24	2022-09-30	宁夏泰胜生物科技有限公司	一种利用雪白白疆菌发酵生产环孢菌素的培养基和培养方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4117118A (en) *	1976-04-09	1978-09-26	Sandoz Ltd.	Organic compounds
CH633826A5 (en) *	1977-04-06	1982-12-31	Sandoz Ag	Process for the preparation of a novel antibiotic
DE2819094A1 (de) *	1977-05-10	1978-11-23	Sandoz Ag	Cyclosporin-derivate, ihre verwendung und herstellung
US4215199A (en) *	1978-06-05	1980-07-29	Sandoz Ltd.	Antibiotic production
SE448386B (sv) *	1978-10-18	1987-02-16	Sandoz Ag	Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
DE3260468D1 (en) *	1981-01-09	1984-09-06	Sandoz Ag	Novel cyclosporins
JPS5877894A (ja) *	1981-11-05	1983-05-11	Mitsui Toatsu Chem Inc	蛋白質の除去方法
CH667274A5 (de) *	1984-03-23	1988-09-30	Sandoz Ag	Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE3888357T2 (de) *	1987-06-22	1994-09-15	Merck & Co Inc	Cyclosporin-Derivate, die eine modifizierte Aminosäure auf Stellung 8 tragen.
HU201577B (en) *	1988-12-20	1990-11-28	Gyogyszerkutato Intezet	Process for producing cyclosporin antibiotics
JPH02216453A (ja) *	1989-02-17	1990-08-29	Sekisui Chem Co Ltd	シクロスポリンの測定法
DE69222150T2 (de) *	1991-01-25	1998-01-15	Fujisawa Pharmaceutical Co	Prozess zur produktion von cyclosporin-a und/oder c
DE59106428D1 (de) *	1991-04-06	1995-10-12	Dresden Arzneimittel	Verfahren zur fermentativen Herstellung und Isolierung von Cyclosporin A sowie neue Cyclosporin- bildende Stämme.
HU213553B (en) *	1992-05-25	1997-07-28	Biogal Gyogyszergyar	Process for isolating of cyclosporin-a
FI92334C (fi) *	1992-12-30	1994-10-25	Leiras Oy	Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
FR2723846B1 (fr) *	1994-08-24	1997-06-13	Hi Pharmtech	Forme pharmaceutique solide pour l'administration d'une substance active liquide liposoluble
KR100304324B1 (ko) *	1994-10-13	2001-11-22	김용규	사이클로스포린a의제조방법
KR0126610B1 (ko) *	1994-10-18	1997-12-29	김충환	고생산 세포융합변이균주에 의한 사이클로스포린 a의 제조방법

1996
- 1996-06-05 US US08/658,653 patent/US5747330A/en not_active Expired - Lifetime
1997
- 1997-03-05 US US08/810,077 patent/US5801020A/en not_active Expired - Lifetime
- 1997-06-05 DE DE69730497T patent/DE69730497D1/de not_active Expired - Lifetime
- 1997-06-05 WO PCT/IB1997/000914 patent/WO1997046575A1/en not_active Ceased
- 1997-06-05 EP EP97923272A patent/EP0906336B1/de not_active Expired - Lifetime
- 1997-06-05 CA CA002257254A patent/CA2257254C/en not_active Expired - Fee Related
- 1997-06-05 AU AU29122/97A patent/AU2912297A/en not_active Abandoned
- 1997-06-05 WO PCT/IB1997/000654 patent/WO1997046580A1/en not_active Ceased
- 1997-06-05 ES ES97923272T patent/ES2227693T3/es not_active Expired - Lifetime
- 1997-06-05 AT AT97923272T patent/ATE275153T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
US5801020A (en)	1998-09-01
ES2227693T3 (es)	2005-04-01
EP0906336A1 (de)	1999-04-07
EP0906336B1 (de)	2004-09-01
US5747330A (en)	1998-05-05
CA2257254C (en)	2002-08-13
WO1997046580A1 (en)	1997-12-11
WO1997046575A1 (en)	1997-12-11
CA2257254A1 (en)	1997-12-11
AU2912297A (en)	1998-01-05
DE69730497D1 (de)	2004-10-07

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Legal Events

Date	Code	Title	Description
2005-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties