ATE278672T1 - Verfahren zur herstellung von (s)-n-tertbutyl-1,2,3,4- tetrahydroisochinolin-3-carboxamid - Google Patents
Verfahren zur herstellung von (s)-n-tertbutyl-1,2,3,4- tetrahydroisochinolin-3-carboxamidInfo
- Publication number
- ATE278672T1 ATE278672T1 AT00811108T AT00811108T ATE278672T1 AT E278672 T1 ATE278672 T1 AT E278672T1 AT 00811108 T AT00811108 T AT 00811108T AT 00811108 T AT00811108 T AT 00811108T AT E278672 T1 ATE278672 T1 AT E278672T1
- Authority
- AT
- Austria
- Prior art keywords
- tertbutyl
- carboxamide
- tetrahydroisocinoline
- producing
- tetrahydroisoquinoline
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- DMJXRYSGXCLCFP-LBPRGKRZSA-N (3s)-n-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide Chemical compound C1=CC=C2CN[C@H](C(=O)NC(C)(C)C)CC2=C1 DMJXRYSGXCLCFP-LBPRGKRZSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI002457A IT1313682B1 (it) | 1999-11-25 | 1999-11-25 | Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE278672T1 true ATE278672T1 (de) | 2004-10-15 |
Family
ID=11384015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00811108T ATE278672T1 (de) | 1999-11-25 | 2000-11-22 | Verfahren zur herstellung von (s)-n-tertbutyl-1,2,3,4- tetrahydroisochinolin-3-carboxamid |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6433177B1 (de) |
| EP (1) | EP1104755B1 (de) |
| JP (1) | JP2001163860A (de) |
| KR (1) | KR20010051886A (de) |
| AT (1) | ATE278672T1 (de) |
| DE (1) | DE60014556T2 (de) |
| ES (1) | ES2228442T3 (de) |
| HU (1) | HUP0004717A2 (de) |
| IT (1) | IT1313682B1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1300115C (zh) * | 2004-03-26 | 2007-02-14 | 厦门大学 | 一种合成1，2，3，4－四氢异喹啉衍生物的方法 |
| AR058400A1 (es) * | 2005-12-22 | 2008-01-30 | Schering Corp | Derivados de oxazoloisoquinolina como antagonistas del receptor de trombina |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8927913D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
| JP3204368B2 (ja) * | 1995-06-30 | 2001-09-04 | 味の素株式会社 | 光学活性アミド類の製法 |
| ES2135171T5 (es) * | 1995-06-30 | 2006-03-16 | Ajinomoto Co., Inc. | Procedimiento para producir amidas opticamente activas. |
| US5587481A (en) * | 1996-02-20 | 1996-12-24 | The Monsanto Company | Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide |
| JPH10291979A (ja) | 1997-04-21 | 1998-11-04 | Ichikawa Gosei Kagaku Kk | １，２，３，４−テトラヒドロイソキノリン−３−カルボン酸ターシャリーブチルアミドの製造方法 |
| IT1301825B1 (it) * | 1998-06-26 | 2000-07-07 | Archimica Spa | Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide. |
-
1999
- 1999-11-25 IT IT1999MI002457A patent/IT1313682B1/it active
-
2000
- 2000-01-06 US US09/478,657 patent/US6433177B1/en not_active Expired - Fee Related
- 2000-11-22 ES ES00811108T patent/ES2228442T3/es not_active Expired - Lifetime
- 2000-11-22 AT AT00811108T patent/ATE278672T1/de not_active IP Right Cessation
- 2000-11-22 DE DE60014556T patent/DE60014556T2/de not_active Expired - Fee Related
- 2000-11-22 EP EP00811108A patent/EP1104755B1/de not_active Expired - Lifetime
- 2000-11-23 KR KR1020000069801A patent/KR20010051886A/ko not_active Abandoned
- 2000-11-24 JP JP2000357141A patent/JP2001163860A/ja active Pending
- 2000-11-24 HU HU0004717A patent/HUP0004717A2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI992457A0 (it) | 1999-11-25 |
| DE60014556D1 (de) | 2004-11-11 |
| ITMI992457A1 (it) | 2001-05-25 |
| EP1104755A1 (de) | 2001-06-06 |
| JP2001163860A (ja) | 2001-06-19 |
| KR20010051886A (ko) | 2001-06-25 |
| EP1104755B1 (de) | 2004-10-06 |
| IT1313682B1 (it) | 2002-09-09 |
| DE60014556T2 (de) | 2005-02-03 |
| US6433177B1 (en) | 2002-08-13 |
| ES2228442T3 (es) | 2005-04-16 |
| HUP0004717A2 (hu) | 2002-11-28 |
| HU0004717D0 (de) | 2001-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |